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The map label for this gene is cya3 [H]

Identifier: 170751087

GI number: 170751087

Start: 5003651

End: 5005627

Strand: Direct

Name: cya3 [H]

Synonym: Mrad2831_4701

Alternate gene names: 170751087

Gene position: 5003651-5005627 (Clockwise)

Preceding gene: 170751085

Following gene: 170751093

Centisome position: 82.33

GC content: 58.37

Gene sequence:

>1977_bases
TTGGACAGGCCCGTCGAGCGCCGTCTCGCGGCGATCTTGATCACGGACATCGTCGGCTACAGCCGGATGGTCTCTCATGA
TGAGGCCGGGACGCTGCGCCGCCTGCGGGCCTTGCGCCGCGAGATCATCGATCCACACATCGCTGCCGCTCGCGGCCGCA
TCGTCAAGTCCACAGGCGACGGCGTGCTGGCCGAATTCCCGAGTTCGGTCCGCGCCGTGAACTGCGCCGTCGCCATCCAG
AAGGCGGCCGCCACCTTCAATGCTGATCGCCCCGAAGCCGAAGCGATGCATATGCGTATCGGCATCAATCTCGGGGATGT
GGTGGCTGAGCCGGACGGTGATTTGTTCGGCGATGGTGTTAACGTAGCGGCGCGCCTGGAGCCGCTGGCTGAGGCCGGCG
GCCTGTGCATCTCGCGCTCGATCCACGACCAAGTGCGCGACAAACTTCCGTATCGCTTCGCGGATCACGGCAAGATAGAA
CTGAAGAACATCGCCCGCCCTATCGGTGTCTTCGCGCTCTCCGCTGAGGCCATCGCGGCCATTCCCGACCCGCCCGATGA
GGATGAACGGGATCCGGTGCTTGAGCCCAGGGCCGAGGCACATCGGCAGCGCGGGCTGCGGGCGATTGTGGCAGCCGTTC
TGATTGGCCTCGGCTTGGCGAGCGGCGCGGGTCTATGGGGCAGGGCTACGAAGACGCCAACGGCCGATCACACCTTGGCC
GTGCAGGCCGGCTTGCCGCCCAAGCCGCTACCGCCGCTCTCACTGGTGGTGTTGCCCTTCGCCAACCTCAGCAGCGACCC
GGAGCAGGAGTTCTTCGCTGACGGTCTCACCGAGGATCTAACAACCGACCTGTCCCATCTGGCCGGCAGCTTCGTCATCG
CGCGCAACACGGCTTTCACATACAAGAACAAGCCTGTCGACGTGAGGCAACTGGGTCGCGATCTGGGTGTTCGCTATGTT
CTAGAAGGCAGTGTCCGCAGAGCGAATGATAAAATCTTATTGAATGCCCAATTGATTGAAACGGAAGCAGGTTCAGCGAT
CTGGTCGGACCGGTTTGAAGGCGAGAGGAGTCGTGTCGGAGAGATACAGACAGAGTTCGTGGCCAGATTGGCTCGCTCGC
TGGATGTGCAATTGATGAGAGCGGAAAGTCTGCGCTCTCTCAGGGAAAGACCCAATAATCCTGATGCCTCCGACTTGGCG
ATGCGCGGATGGGCCGCTCTGAACAGGATTCGGACTCCTGAGAACACGAGGGATGGCATAAGTTACTTCGAGCATGCGCT
AACAATTGACAAGGATTTGCCAAGTGCACAATTGGGCTTAGCGAGAGCGCTTTCTGTTTTGGCGGGTTCTGGCTGGAGTT
CAGATCGACAAGCCGACGTTTCGCGCGCGGATGACATTGTCACTCCGTTTCTGCTTGCCAATCCGACCAATGCGTTGGCT
CACTATATCAAAGGGGGCGTCTACAGAACGCGAAAACAATTCGATCAAGCTACGGCGGAACTCGATCAGGCGATTTTTTA
CGACCCCAACTTCGCGGATGCCTATGACCAAGCCGGTTTGGTGCGCCTGCTGAACGGGCAATCGAAAGAGATCTTTCCTT
TTTCGATGAAGGCCATCAGATTGAGTCCGCAGGATCCGTATGTCGGATACTGGACCTTCCACATCTGTCATAGGCATAGT
CATCTCGCGCAGTGGCAGCAGGCCGTCGTTTGGTGCAATAAGTCTATAGCTCATACACCGTATTGGGCAGCTTATATTGA
TCTTGCGACCGCCTATGCTTGGCTCGGCAAGAAGGCGGAGGCGAGCAGAGCGGTTGCGGAGTTGCTCAAATTAATGCCAG
GATATACGGTTCAGAAGTGGGCCAACTTTGGCGTTTCTGATAATCCAGTCTTTCTAGAAGCGTACAAAGCGATGGTGCAA
GGTCTGAGGATGGCCGGCTTACCGGAGGGTATGACCGATCAGTCTGCGCGCAAATAG

Upstream 100 bases:

>100_bases
GCTCAGATTTCAACCTGCGCCACTATCAGCGGCTGACAGTAGCCGAGAGGCGTAGCCGTGATAAGATATTCATCGGAAGT
CTGAGCCGAAGGAGGCGGTT

Downstream 100 bases:

>100_bases
ATGAATTCTGAAAATCTCACAGCGAGACCGAGCATCTAGGTAAGATTCAACAGGGGCCGGAGATTTAGCTCCGGCCGGTC
TTTTTACTGCAGCGACGACG

Product: TPR repeat-containing adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 3; Adenylyl cyclase 3 [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MDRPVERRLAAILITDIVGYSRMVSHDEAGTLRRLRALRREIIDPHIAAARGRIVKSTGDGVLAEFPSSVRAVNCAVAIQ
KAAATFNADRPEAEAMHMRIGINLGDVVAEPDGDLFGDGVNVAARLEPLAEAGGLCISRSIHDQVRDKLPYRFADHGKIE
LKNIARPIGVFALSAEAIAAIPDPPDEDERDPVLEPRAEAHRQRGLRAIVAAVLIGLGLASGAGLWGRATKTPTADHTLA
VQAGLPPKPLPPLSLVVLPFANLSSDPEQEFFADGLTEDLTTDLSHLAGSFVIARNTAFTYKNKPVDVRQLGRDLGVRYV
LEGSVRRANDKILLNAQLIETEAGSAIWSDRFEGERSRVGEIQTEFVARLARSLDVQLMRAESLRSLRERPNNPDASDLA
MRGWAALNRIRTPENTRDGISYFEHALTIDKDLPSAQLGLARALSVLAGSGWSSDRQADVSRADDIVTPFLLANPTNALA
HYIKGGVYRTRKQFDQATAELDQAIFYDPNFADAYDQAGLVRLLNGQSKEIFPFSMKAIRLSPQDPYVGYWTFHICHRHS
HLAQWQQAVVWCNKSIAHTPYWAAYIDLATAYAWLGKKAEASRAVAELLKLMPGYTVQKWANFGVSDNPVFLEAYKAMVQ
GLRMAGLPEGMTDQSARK

Sequences:

>Translated_658_residues
MDRPVERRLAAILITDIVGYSRMVSHDEAGTLRRLRALRREIIDPHIAAARGRIVKSTGDGVLAEFPSSVRAVNCAVAIQ
KAAATFNADRPEAEAMHMRIGINLGDVVAEPDGDLFGDGVNVAARLEPLAEAGGLCISRSIHDQVRDKLPYRFADHGKIE
LKNIARPIGVFALSAEAIAAIPDPPDEDERDPVLEPRAEAHRQRGLRAIVAAVLIGLGLASGAGLWGRATKTPTADHTLA
VQAGLPPKPLPPLSLVVLPFANLSSDPEQEFFADGLTEDLTTDLSHLAGSFVIARNTAFTYKNKPVDVRQLGRDLGVRYV
LEGSVRRANDKILLNAQLIETEAGSAIWSDRFEGERSRVGEIQTEFVARLARSLDVQLMRAESLRSLRERPNNPDASDLA
MRGWAALNRIRTPENTRDGISYFEHALTIDKDLPSAQLGLARALSVLAGSGWSSDRQADVSRADDIVTPFLLANPTNALA
HYIKGGVYRTRKQFDQATAELDQAIFYDPNFADAYDQAGLVRLLNGQSKEIFPFSMKAIRLSPQDPYVGYWTFHICHRHS
HLAQWQQAVVWCNKSIAHTPYWAAYIDLATAYAWLGKKAEASRAVAELLKLMPGYTVQKWANFGVSDNPVFLEAYKAMVQ
GLRMAGLPEGMTDQSARK
>Mature_658_residues
MDRPVERRLAAILITDIVGYSRMVSHDEAGTLRRLRALRREIIDPHIAAARGRIVKSTGDGVLAEFPSSVRAVNCAVAIQ
KAAATFNADRPEAEAMHMRIGINLGDVVAEPDGDLFGDGVNVAARLEPLAEAGGLCISRSIHDQVRDKLPYRFADHGKIE
LKNIARPIGVFALSAEAIAAIPDPPDEDERDPVLEPRAEAHRQRGLRAIVAAVLIGLGLASGAGLWGRATKTPTADHTLA
VQAGLPPKPLPPLSLVVLPFANLSSDPEQEFFADGLTEDLTTDLSHLAGSFVIARNTAFTYKNKPVDVRQLGRDLGVRYV
LEGSVRRANDKILLNAQLIETEAGSAIWSDRFEGERSRVGEIQTEFVARLARSLDVQLMRAESLRSLRERPNNPDASDLA
MRGWAALNRIRTPENTRDGISYFEHALTIDKDLPSAQLGLARALSVLAGSGWSSDRQADVSRADDIVTPFLLANPTNALA
HYIKGGVYRTRKQFDQATAELDQAIFYDPNFADAYDQAGLVRLLNGQSKEIFPFSMKAIRLSPQDPYVGYWTFHICHRHS
HLAQWQQAVVWCNKSIAHTPYWAAYIDLATAYAWLGKKAEASRAVAELLKLMPGYTVQKWANFGVSDNPVFLEAYKAMVQ
GLRMAGLPEGMTDQSARK

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00515 TPR_1 [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 72212; Mature: 72212

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRPVERRLAAILITDIVGYSRMVSHDEAGTLRRLRALRREIIDPHIAAARGRIVKSTGD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCC
GVLAEFPSSVRAVNCAVAIQKAAATFNADRPEAEAMHMRIGINLGDVVAEPDGDLFGDGV
CHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEECCCHHHEEECCCCCCCCCCC
NVAARLEPLAEAGGLCISRSIHDQVRDKLPYRFADHGKIELKNIARPIGVFALSAEAIAA
CHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCEECCCCCEEHHHHHHHHHHEEECCCHHEE
IPDPPDEDERDPVLEPRAEAHRQRGLRAIVAAVLIGLGLASGAGLWGRATKTPTADHTLA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
VQAGLPPKPLPPLSLVVLPFANLSSDPEQEFFADGLTEDLTTDLSHLAGSFVIARNTAFT
EECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCEEEEECCEEE
YKNKPVDVRQLGRDLGVRYVLEGSVRRANDKILLNAQLIETEAGSAIWSDRFEGERSRVG
ECCCCCCHHHHHHHHCEEEEEECCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCHHHHH
EIQTEFVARLARSLDVQLMRAESLRSLRERPNNPDASDLAMRGWAALNRIRTPENTRDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
SYFEHALTIDKDLPSAQLGLARALSVLAGSGWSSDRQADVSRADDIVTPFLLANPTNALA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHCCCCHHHHH
HYIKGGVYRTRKQFDQATAELDQAIFYDPNFADAYDQAGLVRLLNGQSKEIFPFSMKAIR
HHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCHHHHHCCCCCCCCCEEEEEEE
LSPQDPYVGYWTFHICHRHSHLAQWQQAVVWCNKSIAHTPYWAAYIDLATAYAWLGKKAE
ECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHH
ASRAVAELLKLMPGYTVQKWANFGVSDNPVFLEAYKAMVQGLRMAGLPEGMTDQSARK
HHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDRPVERRLAAILITDIVGYSRMVSHDEAGTLRRLRALRREIIDPHIAAARGRIVKSTGD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCC
GVLAEFPSSVRAVNCAVAIQKAAATFNADRPEAEAMHMRIGINLGDVVAEPDGDLFGDGV
CHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEECCCHHHEEECCCCCCCCCCC
NVAARLEPLAEAGGLCISRSIHDQVRDKLPYRFADHGKIELKNIARPIGVFALSAEAIAA
CHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCEECCCCCEEHHHHHHHHHHEEECCCHHEE
IPDPPDEDERDPVLEPRAEAHRQRGLRAIVAAVLIGLGLASGAGLWGRATKTPTADHTLA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
VQAGLPPKPLPPLSLVVLPFANLSSDPEQEFFADGLTEDLTTDLSHLAGSFVIARNTAFT
EECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCEEEEECCEEE
YKNKPVDVRQLGRDLGVRYVLEGSVRRANDKILLNAQLIETEAGSAIWSDRFEGERSRVG
ECCCCCCHHHHHHHHCEEEEEECCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCHHHHH
EIQTEFVARLARSLDVQLMRAESLRSLRERPNNPDASDLAMRGWAALNRIRTPENTRDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
SYFEHALTIDKDLPSAQLGLARALSVLAGSGWSSDRQADVSRADDIVTPFLLANPTNALA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHCCCCHHHHH
HYIKGGVYRTRKQFDQATAELDQAIFYDPNFADAYDQAGLVRLLNGQSKEIFPFSMKAIR
HHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCHHHHHCCCCCCCCCEEEEEEE
LSPQDPYVGYWTFHICHRHSHLAQWQQAVVWCNKSIAHTPYWAAYIDLATAYAWLGKKAE
ECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHH
ASRAVAELLKLMPGYTVQKWANFGVSDNPVFLEAYKAMVQGLRMAGLPEGMTDQSARK
HHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10485295; 11481432 [H]