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The map label for this gene is glmU [H]

Identifier: 170751001

GI number: 170751001

Start: 4907826

End: 4908374

Strand: Direct

Name: glmU [H]

Synonym: Mrad2831_4612

Alternate gene names: 170751001

Gene position: 4907826-4908374 (Clockwise)

Preceding gene: 170750996

Following gene: 170751002

Centisome position: 80.75

GC content: 68.31

Gene sequence:

>549_bases
ATGCCGATTACCGATGCGGATATTGGGTCAGATGTGGGTATCTTCTACCCGGATCTAGTCAATATTTATGGATGTCGAAT
CGAAAGCGGTTCGCGCATCGGCCCCTTCGTCGAGATCCAGCGCGGCAGCCGGATCGGCCCGCGCTGCAAGATCTCCTCGC
ACAGCTTCATCTGCGCGGGCGTCTCGATCGGGGCCGAGGTGTTCGTCGGCCACGGCGTGGTCTTCACCAACGAGCTGTAT
CCGGAAGCCACCAACGCGGACGGCAGCCTGAAGCGGGACGGCGAGTGGGAGCTCGTCGAGACCGTGGTCGAGGCCCGCGC
CTCCATCGGCTCCAACGCCACCATCGTGGCGGGGATCACCATCGGCGAGGGCGCCCTGGTCGGCGCCGGTGCCGTCGTCA
CCCGGGACGTCCCGGCCTTCGCCATCGTCGCCGGATGCCCCGCGCGGGTCGTCGGCGACACGCGCACCAAGCGCGCCGAG
AGCGCCGCGCGCGCCCGTTCCGTCCAGTCGCCGCGGCCCGAGCCGGCCGAGCCTCTGCAGGTTGCTTGA

Upstream 100 bases:

>100_bases
GCCTTTCGACGGACGAACCGCATCGAAAGCCTGGGTTCCCGGCCGTCCGTAGCTCTGTGCAGTTTTGACGCACAGAAGTT
GTGCGGAAGGAGCGGCGGTT

Downstream 100 bases:

>100_bases
GGGGAATGCAGTCATGATCTCGATCGGTATCGTCGGCTACGGCTACTGGGGGCCGAACCTCGCCCGGTGCACCTCGGAGA
GCGAGCGCTGCCAGCTGGTG

Product: hexapaptide repeat-containing transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MPITDADIGSDVGIFYPDLVNIYGCRIESGSRIGPFVEIQRGSRIGPRCKISSHSFICAGVSIGAEVFVGHGVVFTNELY
PEATNADGSLKRDGEWELVETVVEARASIGSNATIVAGITIGEGALVGAGAVVTRDVPAFAIVAGCPARVVGDTRTKRAE
SAARARSVQSPRPEPAEPLQVA

Sequences:

>Translated_182_residues
MPITDADIGSDVGIFYPDLVNIYGCRIESGSRIGPFVEIQRGSRIGPRCKISSHSFICAGVSIGAEVFVGHGVVFTNELY
PEATNADGSLKRDGEWELVETVVEARASIGSNATIVAGITIGEGALVGAGAVVTRDVPAFAIVAGCPARVVGDTRTKRAE
SAARARSVQSPRPEPAEPLQVA
>Mature_181_residues
PITDADIGSDVGIFYPDLVNIYGCRIESGSRIGPFVEIQRGSRIGPRCKISSHSFICAGVSIGAEVFVGHGVVFTNELYP
EATNADGSLKRDGEWELVETVVEARASIGSNATIVAGITIGEGALVGAGAVVTRDVPAFAIVAGCPARVVGDTRTKRAES
AARARSVQSPRPEPAEPLQVA

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 18937; Mature: 18805

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITDADIGSDVGIFYPDLVNIYGCRIESGSRIGPFVEIQRGSRIGPRCKISSHSFICAG
CCCCCCCCCCCCCEECCCHHCEEEEEECCCCCCCCEEEECCCCCCCCEEEECCCCEEEEE
VSIGAEVFVGHGVVFTNELYPEATNADGSLKRDGEWELVETVVEARASIGSNATIVAGIT
CCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEE
IGEGALVGAGAVVTRDVPAFAIVAGCPARVVGDTRTKRAESAARARSVQSPRPEPAEPLQ
ECCCCEECCCEEEECCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCC
VA
CC
>Mature Secondary Structure 
PITDADIGSDVGIFYPDLVNIYGCRIESGSRIGPFVEIQRGSRIGPRCKISSHSFICAG
CCCCCCCCCCCCEECCCHHCEEEEEECCCCCCCCEEEECCCCCCCCEEEECCCCEEEEE
VSIGAEVFVGHGVVFTNELYPEATNADGSLKRDGEWELVETVVEARASIGSNATIVAGIT
CCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEE
IGEGALVGAGAVVTRDVPAFAIVAGCPARVVGDTRTKRAESAARARSVQSPRPEPAEPLQ
ECCCCEECCCEEEECCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCC
VA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA