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The map label for this gene is ptxB [H]

Identifier: 170750963

GI number: 170750963

Start: 4869058

End: 4870080

Strand: Direct

Name: ptxB [H]

Synonym: Mrad2831_4574

Alternate gene names: 170750963

Gene position: 4869058-4870080 (Clockwise)

Preceding gene: 170750962

Following gene: 170750964

Centisome position: 80.11

GC content: 68.33

Gene sequence:

>1023_bases
GTGACGATCGCCCGATACGGCGCAGCCCTGGCGCTGCTCTGCGGCTTCGGTTTCCCGTCGCCCCTCAGGGCCGACGAGTG
CCCCAACCGCGGCCAGCTCGACGACGCCTACTGCGACGCCAACAAGGACCTCGTCGCCGACGTCCCGGCCAAGACCCGCG
ACCCGAGCGTGATCGTCTTCGCCTACACGCCGGTGGAGGATCCCGCGGTCTACGAGAACTCGTTCAAGCCGTTCACGACC
TACCTGAGCCAGTGCACGGGCAAGCGCGTCGTCTACTACCCGGTCCAGTCGAACTCGGCCGAGATCGAGGCGATGCGCTC
GGGTCGGCTCACGGTGGCGGGCTTCTCGACCGGCCCGCTCGGCTTCGCGGTGAACATGGCCGGCGCGGTGCCGTTCGCCG
CCAAGGGCACCGAGAAGGGCGCCGAGGGCTACAACCTGATCGTGGTGGTGAAGGCGAGCAGCCCGTACAAGACGCTGGCC
GACCTCAAGGGCAAGCGCGTGGCCCACACGGCGCCGTCGTCGAATTCCGGCAACCTCGCGCCCAAGGCGCTGTTTCCCGA
GCAGGGGCTGAAGCCCGGCGAGGACTACAAGCTCATCTACTCGGGCGGCCACGACAAGTCGGCGCTGGGCGTCGGCACCG
GCGACTACGACGCCGCCCCGGTGGCCTCGGACGTGTTCTACCGGATGGTCGCCCGCGGCACGATCAAGGGCGACGATTAC
CGGGTGATCTACACGAGCGAGAAGTTCCCGACCTCGGGCTTCGCCTACGCCCACGATCTCAAGCCGGAACTCGCCGAGAA
GCTGAAGCAGTGCTTCTACGATTTCCGCTTCCCGCCCGACATGGTGAAGGATTTCGAGGGCGACGACCGGTTCGCGCCGA
TCACCTACCTCAAGGACTGGGCGATCGTCCGCAAGGTCGCGGAGGAATCGGGCACGCCGTACAACAAGGCCGCCTACGAG
CGCGAGGCCGCCCGCGAGGCCGAGGCCGCCCGCAAGAAGGCCGCGGGCGCGCCCAAGCCGTGA

Upstream 100 bases:

>100_bases
GTCAGCCGGCGCCTACACCTTTGCCGGCTCAAGCTCGGCCCGGACCGGGCGGGACATGACGGCGCCGGCCCGAGGCACGG
CCCCGCAGGGAGGATAGCGC

Downstream 100 bases:

>100_bases
TTCAGGCCGTGACGCAGGCCGTGACGGCGGGGAGCGCGGCGCGCGCGGTGGCGGCCGGACCTGAGGGTGATCCCCGGGCG
GAGGATCCGCGCGCGCTGGT

Product: phosphonate ABC transporter periplasmic phosphonate-binding protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTIARYGAALALLCGFGFPSPLRADECPNRGQLDDAYCDANKDLVADVPAKTRDPSVIVFAYTPVEDPAVYENSFKPFTT
YLSQCTGKRVVYYPVQSNSAEIEAMRSGRLTVAGFSTGPLGFAVNMAGAVPFAAKGTEKGAEGYNLIVVVKASSPYKTLA
DLKGKRVAHTAPSSNSGNLAPKALFPEQGLKPGEDYKLIYSGGHDKSALGVGTGDYDAAPVASDVFYRMVARGTIKGDDY
RVIYTSEKFPTSGFAYAHDLKPELAEKLKQCFYDFRFPPDMVKDFEGDDRFAPITYLKDWAIVRKVAEESGTPYNKAAYE
REAAREAEAARKKAAGAPKP

Sequences:

>Translated_340_residues
MTIARYGAALALLCGFGFPSPLRADECPNRGQLDDAYCDANKDLVADVPAKTRDPSVIVFAYTPVEDPAVYENSFKPFTT
YLSQCTGKRVVYYPVQSNSAEIEAMRSGRLTVAGFSTGPLGFAVNMAGAVPFAAKGTEKGAEGYNLIVVVKASSPYKTLA
DLKGKRVAHTAPSSNSGNLAPKALFPEQGLKPGEDYKLIYSGGHDKSALGVGTGDYDAAPVASDVFYRMVARGTIKGDDY
RVIYTSEKFPTSGFAYAHDLKPELAEKLKQCFYDFRFPPDMVKDFEGDDRFAPITYLKDWAIVRKVAEESGTPYNKAAYE
REAAREAEAARKKAAGAPKP
>Mature_339_residues
TIARYGAALALLCGFGFPSPLRADECPNRGQLDDAYCDANKDLVADVPAKTRDPSVIVFAYTPVEDPAVYENSFKPFTTY
LSQCTGKRVVYYPVQSNSAEIEAMRSGRLTVAGFSTGPLGFAVNMAGAVPFAAKGTEKGAEGYNLIVVVKASSPYKTLAD
LKGKRVAHTAPSSNSGNLAPKALFPEQGLKPGEDYKLIYSGGHDKSALGVGTGDYDAAPVASDVFYRMVARGTIKGDDYR
VIYTSEKFPTSGFAYAHDLKPELAEKLKQCFYDFRFPPDMVKDFEGDDRFAPITYLKDWAIVRKVAEESGTPYNKAAYER
EAAREAEAARKKAAGAPKP

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 36822; Mature: 36691

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIARYGAALALLCGFGFPSPLRADECPNRGQLDDAYCDANKDLVADVPAKTRDPSVIVF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCCCCCCEEEE
AYTPVEDPAVYENSFKPFTTYLSQCTGKRVVYYPVQSNSAEIEAMRSGRLTVAGFSTGPL
EECCCCCCCHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCEEEEECCCCCC
GFAVNMAGAVPFAAKGTEKGAEGYNLIVVVKASSPYKTLADLKGKRVAHTAPSSNSGNLA
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCC
PKALFPEQGLKPGEDYKLIYSGGHDKSALGVGTGDYDAAPVASDVFYRMVARGTIKGDDY
CCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCE
RVIYTSEKFPTSGFAYAHDLKPELAEKLKQCFYDFRFPPDMVKDFEGDDRFAPITYLKDW
EEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEECHHHHHHH
AIVRKVAEESGTPYNKAAYEREAAREAEAARKKAAGAPKP
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TIARYGAALALLCGFGFPSPLRADECPNRGQLDDAYCDANKDLVADVPAKTRDPSVIVF
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCCCCCCEEEE
AYTPVEDPAVYENSFKPFTTYLSQCTGKRVVYYPVQSNSAEIEAMRSGRLTVAGFSTGPL
EECCCCCCCHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCEEEEECCCCCC
GFAVNMAGAVPFAAKGTEKGAEGYNLIVVVKASSPYKTLADLKGKRVAHTAPSSNSGNLA
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCC
PKALFPEQGLKPGEDYKLIYSGGHDKSALGVGTGDYDAAPVASDVFYRMVARGTIKGDDY
CCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCE
RVIYTSEKFPTSGFAYAHDLKPELAEKLKQCFYDFRFPPDMVKDFEGDDRFAPITYLKDW
EEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEECHHHHHHH
AIVRKVAEESGTPYNKAAYEREAAREAEAARKKAAGAPKP
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]