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The map label for this gene is yciR [C]

Identifier: 170750828

GI number: 170750828

Start: 4720856

End: 4722829

Strand: Reverse

Name: yciR [C]

Synonym: Mrad2831_4439

Alternate gene names: 170750828

Gene position: 4722829-4720856 (Counterclockwise)

Preceding gene: 170750835

Following gene: 170750823

Centisome position: 77.71

GC content: 70.97

Gene sequence:

>1974_bases
ATGAACCGTCCTAGACATCTGCTCTCGTTACTGATCGCGTCGTTGACCGCATCCGCCCGCGGCCTGACCGCCACGCGTCA
GCTCGCGGAGCTGCAGAAGCAGGTCCCGAGCCTCTACGGCCTGCTCTCGGTCAATGCCGGCGCCCTCGCCGTGACGCATT
ACGGTCTGGCGCCCGCTTTCCTGACGCTCGGCATCCCGGCCGTCGTGATCTCGCTGTGCGTGGTGCGGGCGGCGCACTGG
CTGCGGCTGCGGCCCGAGACGTTCGGCGAAGCGCGGGCGTCCCGTCACCTGCGGCTGACCACGGTGCTCACGGCCTTCTT
CTCGGTCGCCTTCGTGATCTGGGCGATGGTCCTGAACCGGTACGGCGGCCCCTACGAGCAGGGCCACGTGGCGATCTTCG
TGGCCGTCACGGTGATCGCCTGCATCTTCTGCCTGACGCACCTGCCGGTCGCGGCCTTCCTGGTGACCGGCATCGTCATG
AGCGTGTTCCTGTTCTGCTGCGTGACCAGCGGGAACGACGTCTTCCTGGCCATCGCCGCCAACACGGCCTTCGTCACGGC
GGTGATGGTCCGCATCCTCAACACCAACTACCGGGCCTTCGTCGACCTCGTCGCGTCCCAGGCCGTGGCGAGCCGGCTCT
CGGAGGAGAACGCGCGCCTCGCCCAGACGGACAGCCTGACCGGCCTGCCCAACCGGCGCTACTTCTTCCAGAAGCTCGAC
GAGGCGATCCGGTCGTCCGCGGGAACGGAGACACCCTTCGCCCTGGCGATCTTCGACCTCGACCGCTTCAAGCCGATCAA
CGACACCTACGGGCACAATGTCGGCGACCGGGTCCTGGCGGAGGCCGGCCGGCGCCTCGCGGGCTTCGCGGGCGCCGACG
CGGTGGTGACGCGGCTGGGGGGCGACGAGTTCGGCGTGCTGCTGCGCGCGCCGGATTCGGCCGCGGCGGCGCTCGCCTTC
TGCGACGGCGTCTGCACGGCGCTGCAGCAGCCGATCCAGATCGGCGACATCCGGGTCGTCACGGGCTGCTCGGGCGGGCT
CGCCCTGCCCTGCCGGATCTCGCACGACGCCGACGCCCTGTTCGACCGCGCCGACTACGCGCTCTACCACTCCAAGGAGC
AGCGCCGCGGCGCGACGACCCTGTTCTCGCAGGAGCACAAGGACGCGATCCGCGCCGAGCAGGCGGTGGAGACGGCCCTG
CGGACGGCGGATCTCGCCGCCGAGATGGTGCTGCACTACCAGCCGGTCCTCGACCTCGAGACGGGCCGGACCGCCTTCGT
GGAGGGTCTGGCGCGCTGGACGAGCCCGACGCTGGGCCGCGTCGCGCCGGACCGGTTCATCGCGGCCGCCGAGCGCTGCG
GCATGATCCACACGGTGACGCTCCTGCTCCTGCGCAAGGCGCTCGCCGACGGCGCGCGGCTGCCGCCCGGGACCGGCCTG
TCCTTCAACCTCTCCGCCCACGACCTCGCCTCGCCGGAGACCGTCCTGGCGATCCTGGCGGCGGTACGGGGCAGCGGCCT
CGACCCGCGCCGCCTGACGCTCGAACTGACCGAGACCGCCCTGATGCGCGACTTCGATCACGCCAAGGCGGCCATCACCA
CCCTGCGCAGCCTCGGCATCAAGATCGCCCTGGACGATTTCGGGACCGGCTATTCCAGCCTGGGCTACGTCCACCGCCTG
CCCCTGGACAAGATCAAGATCGACCGCGGCTTCATGGCCGACATCGACACGGACCGGGGCTGCAGCCTCGTCTCCGCGAT
CCTGGACCTGTGCCGCAACCTCGGCCTCGACGGGATCGTCGAGGGAATCGAGACGCAGGCCCAGCTGGACGTGGCGCGGC
GGCACGGCAGCCGCTACGCCCAGGGCTACCACATCGGCCGCCCGATGCCCCTCGGCGACCTGCTGGAGCGGCTGGAGCGC
GAGGGCGCGGCGGAAGCAGAGGCAGAGGCCGGCACGGTGCGCCGGAGGGCCTGA

Upstream 100 bases:

>100_bases
CGCGGCCAGGCCCCGGACGACTATTTTCCTCTTTCGTCGCTTAAATGTCTCCTTAATCAATCAAAAATAGTAATAGGAAA
ATAGCGCAGCCACAGCTCCG

Downstream 100 bases:

>100_bases
GGCGGCCCCGGCGCGCGGCGGAGCCGCGCCCTCAGGCGCGCCGGAGGTTCCAGAGGATCGGGAAGCCCGGGAGGCGGCCC
GTCAGGTCGCGCCGGTAGGA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MNRPRHLLSLLIASLTASARGLTATRQLAELQKQVPSLYGLLSVNAGALAVTHYGLAPAFLTLGIPAVVISLCVVRAAHW
LRLRPETFGEARASRHLRLTTVLTAFFSVAFVIWAMVLNRYGGPYEQGHVAIFVAVTVIACIFCLTHLPVAAFLVTGIVM
SVFLFCCVTSGNDVFLAIAANTAFVTAVMVRILNTNYRAFVDLVASQAVASRLSEENARLAQTDSLTGLPNRRYFFQKLD
EAIRSSAGTETPFALAIFDLDRFKPINDTYGHNVGDRVLAEAGRRLAGFAGADAVVTRLGGDEFGVLLRAPDSAAAALAF
CDGVCTALQQPIQIGDIRVVTGCSGGLALPCRISHDADALFDRADYALYHSKEQRRGATTLFSQEHKDAIRAEQAVETAL
RTADLAAEMVLHYQPVLDLETGRTAFVEGLARWTSPTLGRVAPDRFIAAAERCGMIHTVTLLLLRKALADGARLPPGTGL
SFNLSAHDLASPETVLAILAAVRGSGLDPRRLTLELTETALMRDFDHAKAAITTLRSLGIKIALDDFGTGYSSLGYVHRL
PLDKIKIDRGFMADIDTDRGCSLVSAILDLCRNLGLDGIVEGIETQAQLDVARRHGSRYAQGYHIGRPMPLGDLLERLER
EGAAEAEAEAGTVRRRA

Sequences:

>Translated_657_residues
MNRPRHLLSLLIASLTASARGLTATRQLAELQKQVPSLYGLLSVNAGALAVTHYGLAPAFLTLGIPAVVISLCVVRAAHW
LRLRPETFGEARASRHLRLTTVLTAFFSVAFVIWAMVLNRYGGPYEQGHVAIFVAVTVIACIFCLTHLPVAAFLVTGIVM
SVFLFCCVTSGNDVFLAIAANTAFVTAVMVRILNTNYRAFVDLVASQAVASRLSEENARLAQTDSLTGLPNRRYFFQKLD
EAIRSSAGTETPFALAIFDLDRFKPINDTYGHNVGDRVLAEAGRRLAGFAGADAVVTRLGGDEFGVLLRAPDSAAAALAF
CDGVCTALQQPIQIGDIRVVTGCSGGLALPCRISHDADALFDRADYALYHSKEQRRGATTLFSQEHKDAIRAEQAVETAL
RTADLAAEMVLHYQPVLDLETGRTAFVEGLARWTSPTLGRVAPDRFIAAAERCGMIHTVTLLLLRKALADGARLPPGTGL
SFNLSAHDLASPETVLAILAAVRGSGLDPRRLTLELTETALMRDFDHAKAAITTLRSLGIKIALDDFGTGYSSLGYVHRL
PLDKIKIDRGFMADIDTDRGCSLVSAILDLCRNLGLDGIVEGIETQAQLDVARRHGSRYAQGYHIGRPMPLGDLLERLER
EGAAEAEAEAGTVRRRA
>Mature_657_residues
MNRPRHLLSLLIASLTASARGLTATRQLAELQKQVPSLYGLLSVNAGALAVTHYGLAPAFLTLGIPAVVISLCVVRAAHW
LRLRPETFGEARASRHLRLTTVLTAFFSVAFVIWAMVLNRYGGPYEQGHVAIFVAVTVIACIFCLTHLPVAAFLVTGIVM
SVFLFCCVTSGNDVFLAIAANTAFVTAVMVRILNTNYRAFVDLVASQAVASRLSEENARLAQTDSLTGLPNRRYFFQKLD
EAIRSSAGTETPFALAIFDLDRFKPINDTYGHNVGDRVLAEAGRRLAGFAGADAVVTRLGGDEFGVLLRAPDSAAAALAF
CDGVCTALQQPIQIGDIRVVTGCSGGLALPCRISHDADALFDRADYALYHSKEQRRGATTLFSQEHKDAIRAEQAVETAL
RTADLAAEMVLHYQPVLDLETGRTAFVEGLARWTSPTLGRVAPDRFIAAAERCGMIHTVTLLLLRKALADGARLPPGTGL
SFNLSAHDLASPETVLAILAAVRGSGLDPRRLTLELTETALMRDFDHAKAAITTLRSLGIKIALDDFGTGYSSLGYVHRL
PLDKIKIDRGFMADIDTDRGCSLVSAILDLCRNLGLDGIVEGIETQAQLDVARRHGSRYAQGYHIGRPMPLGDLLERLER
EGAAEAEAEAGTVRRRA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=426, Percent_Identity=34.7417840375587, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI87081921, Length=445, Percent_Identity=29.2134831460674, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI226510982, Length=445, Percent_Identity=27.4157303370787, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87081743, Length=257, Percent_Identity=33.0739299610895, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI87081845, Length=245, Percent_Identity=35.5102040816327, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=32.2314049586777, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788502, Length=233, Percent_Identity=35.1931330472103, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786507, Length=254, Percent_Identity=33.4645669291339, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1787055, Length=242, Percent_Identity=33.4710743801653, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI87082096, Length=526, Percent_Identity=25.4752851711027, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081980, Length=233, Percent_Identity=33.0472103004292, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1788381, Length=336, Percent_Identity=28.8690476190476, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788849, Length=276, Percent_Identity=26.8115942028986, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=37.8698224852071, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87081977, Length=177, Percent_Identity=33.8983050847458, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787262, Length=175, Percent_Identity=30.8571428571429, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=32.9479768786127, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786584, Length=252, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787816, Length=173, Percent_Identity=28.9017341040462, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=187, Percent_Identity=30.4812834224599, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=29.6969696969697, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87082007, Length=88, Percent_Identity=40.9090909090909, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787410, Length=218, Percent_Identity=23.394495412844, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 70844; Mature: 70844

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPRHLLSLLIASLTASARGLTATRQLAELQKQVPSLYGLLSVNAGALAVTHYGLAPAF
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
LTLGIPAVVISLCVVRAAHWLRLRPETFGEARASRHLRLTTVLTAFFSVAFVIWAMVLNR
HHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YGGPYEQGHVAIFVAVTVIACIFCLTHLPVAAFLVTGIVMSVFLFCCVTSGNDVFLAIAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NTAFVTAVMVRILNTNYRAFVDLVASQAVASRLSEENARLAQTDSLTGLPNRRYFFQKLD
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHH
EAIRSSAGTETPFALAIFDLDRFKPINDTYGHNVGDRVLAEAGRRLAGFAGADAVVTRLG
HHHHHCCCCCCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHCHHHHCCCCHHHHHHHCC
GDEFGVLLRAPDSAAAALAFCDGVCTALQQPIQIGDIRVVTGCSGGLALPCRISHDADAL
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEECCEEEEEECCCCEEEEEEECCCHHHH
FDRADYALYHSKEQRRGATTLFSQEHKDAIRAEQAVETALRTADLAAEMVLHYQPVLDLE
HHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
TGRTAFVEGLARWTSPTLGRVAPDRFIAAAERCGMIHTVTLLLLRKALADGARLPPGTGL
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
SFNLSAHDLASPETVLAILAAVRGSGLDPRRLTLELTETALMRDFDHAKAAITTLRSLGI
EEECCHHHCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
KIALDDFGTGYSSLGYVHRLPLDKIKIDRGFMADIDTDRGCSLVSAILDLCRNLGLDGIV
EEEEECCCCCHHHCCHHHCCCHHHEEECCCCEECCCCCCCHHHHHHHHHHHHHCCHHHHH
EGIETQAQLDVARRHGSRYAQGYHIGRPMPLGDLLERLEREGAAEAEAEAGTVRRRA
HHHHHHHHHHHHHHCCCHHHCCEECCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MNRPRHLLSLLIASLTASARGLTATRQLAELQKQVPSLYGLLSVNAGALAVTHYGLAPAF
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
LTLGIPAVVISLCVVRAAHWLRLRPETFGEARASRHLRLTTVLTAFFSVAFVIWAMVLNR
HHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YGGPYEQGHVAIFVAVTVIACIFCLTHLPVAAFLVTGIVMSVFLFCCVTSGNDVFLAIAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NTAFVTAVMVRILNTNYRAFVDLVASQAVASRLSEENARLAQTDSLTGLPNRRYFFQKLD
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHH
EAIRSSAGTETPFALAIFDLDRFKPINDTYGHNVGDRVLAEAGRRLAGFAGADAVVTRLG
HHHHHCCCCCCCEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHCHHHHCCCCHHHHHHHCC
GDEFGVLLRAPDSAAAALAFCDGVCTALQQPIQIGDIRVVTGCSGGLALPCRISHDADAL
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEECCEEEEEECCCCEEEEEEECCCHHHH
FDRADYALYHSKEQRRGATTLFSQEHKDAIRAEQAVETALRTADLAAEMVLHYQPVLDLE
HHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
TGRTAFVEGLARWTSPTLGRVAPDRFIAAAERCGMIHTVTLLLLRKALADGARLPPGTGL
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
SFNLSAHDLASPETVLAILAAVRGSGLDPRRLTLELTETALMRDFDHAKAAITTLRSLGI
EEECCHHHCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
KIALDDFGTGYSSLGYVHRLPLDKIKIDRGFMADIDTDRGCSLVSAILDLCRNLGLDGIV
EEEEECCCCCHHHCCHHHCCCHHHEEECCCCEECCCCCCCHHHHHHHHHHHHHCCHHHHH
EGIETQAQLDVARRHGSRYAQGYHIGRPMPLGDLLERLEREGAAEAEAEAGTVRRRA
HHHHHHHHHHHHHHCCCHHHCCEECCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]