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The map label for this gene is livH [C]

Identifier: 170750812

GI number: 170750812

Start: 4701231

End: 4702064

Strand: Direct

Name: livH [C]

Synonym: Mrad2831_4423

Alternate gene names: 170750812

Gene position: 4701231-4702064 (Clockwise)

Preceding gene: 170750811

Following gene: 170750813

Centisome position: 77.35

GC content: 70.14

Gene sequence:

>834_bases
ATGCTGCTCACCCTCGACATCCTGACCACGGCGGCGATCCTGTTCATCGTCTCGATCGGCCTCCTGGCGATCTTCGGCGT
GCTCAAGATCATCAACTTCGCCCACGGGGCGTGGCTGACGGTCGGCGCCTACTGCGCGGTGGTGACCGCCAAGCTCGGGC
TCAATCCATGGGCGGCGCTGCCGCTGGCCTTCGCGGTCGGCGCGGCGCTCGGCGGGCTGGCCGAGCACTTCATCATCCGC
CCGCTCTACCGGCGGCCCCTCGACGCGATCCTCGCGACCTGGGGGCTCGGCATCGTGGTCGGGCAGCTCATCACCCTGGC
CTTCGGCCGGGACGTCCAGCTCACCCCGAACCTCTACGCCGGCACCGTCGAGATCCTCGGCGTCGACTACTCCGCCTACC
GCCTCGTCGCCCTCGGCATCGCGCTCGCGATCGGCACGCTGTTCGCGCTCACCATCGAGCGCACCCGGCTCGGCCTCTCG
GCCCGGGCGGTGATCATGAACGAGACCCTGGCGCGCAGCCTCGGCATCGACACGGGGCGCGTGCGCCTCGTCGTGTTCAT
GCTCGGCGCCGGCTTCGCGGGGCTCGCGGGCGTCCTGCTGACGCCGCTCACCAGCGTCGACCCGAACATGGGCGTCTCCT
GGCTGATCGGCGCCTTCATGCTGGTGATGGTCGCCGACGCCTCGTACCTGGCGCTCGCGGCGGCCTGCCTCGTCTTCGGG
GCCGCGCAGGTTCTGATCAGCACCTTCGTGAGTCCGATCCTGGGCAGCATCGCCGTCGCCGTGCTCGCCGCCCTCGTGCT
GCGGATCAGCCCGAAAGGTTTCTCCCGTGCTTGA

Upstream 100 bases:

>100_bases
GTGTCCGCCGGAGATCCGTGATCACCGTAGCCTCCGCGGGGCAGGGGGCGCGTCGTCACCCGCCGCGTCCTCTGCCGTTC
CCGCGTACCCGGAAACCCCG

Downstream 100 bases:

>100_bases
GACCCTTCCCGTCGCCGAGCGCGCCGCCGCGGCGCCCCGCGGACGCCGCCTGTCCCGCGCCGCGCCCTTCGTGGTCGCGG
CCCTCGCGGCGCTGGCCCTC

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: Urea ABC Transporter Permease Protein UrtB; Branched-Chain Amino Acid ABC Transporter Permease Protein; ABC Transporter Permease Protein; Amino Acid Or Sugar ABC Transport System Permease Protein; ABC Transporter Permease; Branched Chain Amino Acid ABC Transporter Permease; Urea ABC Transporter Permease UrtB; Branched-Chain Amino Acid ABC Transporter Permease; Branched-Chain Amino Acid Transport System Permease Protein; Urea Or Short-Chain Amide ABC Transporter Permease Protein; ABC-Type Urea Transport System Permease Protein I; ABC-Transporter; ABC Transporter; Urea ABC Transporter Permease; ABC-Type Transport System Permease Protein; ABC Transporter Membrane Spanning Protein; Urea/Short-Chain Amide Transport System Permease Protein; Urea/Short-Chain Amide ABC Transporter Permease Protein; Urea Or Short-Chain Amide ABC Transporter; Amide-Urea Transporter Permease Protein; Transmembrane Component Of ABC Transporter; Amino Acid/Sugar ABC Transporter Permease Protein; Branched Chain Inner Membrane Permease Of ABC Transporter; Urea ABC Transporter Permease UrtA; ABC Transporter Inner-Membrane Translocator; ABC Transport System Permease Protein; Branched-Chain/Neutral Amino Acids ABC Transporter Permease; Permease Component Of ABC Transporter Protein; ABC Branched Amino Acid Transporter Permease Component; Branched-Chain Amino Acid Transport System Permease; Amino Acid ABC Transporter Permease; ABC Transporter Subunit; Permease Component Of ABC Transporter; Branched Chain Amino Acid ABC Transporter

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MLLTLDILTTAAILFIVSIGLLAIFGVLKIINFAHGAWLTVGAYCAVVTAKLGLNPWAALPLAFAVGAALGGLAEHFIIR
PLYRRPLDAILATWGLGIVVGQLITLAFGRDVQLTPNLYAGTVEILGVDYSAYRLVALGIALAIGTLFALTIERTRLGLS
ARAVIMNETLARSLGIDTGRVRLVVFMLGAGFAGLAGVLLTPLTSVDPNMGVSWLIGAFMLVMVADASYLALAAACLVFG
AAQVLISTFVSPILGSIAVAVLAALVLRISPKGFSRA

Sequences:

>Translated_277_residues
MLLTLDILTTAAILFIVSIGLLAIFGVLKIINFAHGAWLTVGAYCAVVTAKLGLNPWAALPLAFAVGAALGGLAEHFIIR
PLYRRPLDAILATWGLGIVVGQLITLAFGRDVQLTPNLYAGTVEILGVDYSAYRLVALGIALAIGTLFALTIERTRLGLS
ARAVIMNETLARSLGIDTGRVRLVVFMLGAGFAGLAGVLLTPLTSVDPNMGVSWLIGAFMLVMVADASYLALAAACLVFG
AAQVLISTFVSPILGSIAVAVLAALVLRISPKGFSRA
>Mature_277_residues
MLLTLDILTTAAILFIVSIGLLAIFGVLKIINFAHGAWLTVGAYCAVVTAKLGLNPWAALPLAFAVGAALGGLAEHFIIR
PLYRRPLDAILATWGLGIVVGQLITLAFGRDVQLTPNLYAGTVEILGVDYSAYRLVALGIALAIGTLFALTIERTRLGLS
ARAVIMNETLARSLGIDTGRVRLVVFMLGAGFAGLAGVLLTPLTSVDPNMGVSWLIGAFMLVMVADASYLALAAACLVFG
AAQVLISTFVSPILGSIAVAVLAALVLRISPKGFSRA

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 28802; Mature: 28802

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTLDILTTAAILFIVSIGLLAIFGVLKIINFAHGAWLTVGAYCAVVTAKLGLNPWAAL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHH
PLAFAVGAALGGLAEHFIIRPLYRRPLDAILATWGLGIVVGQLITLAFGRDVQLTPNLYA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHH
GTVEILGVDYSAYRLVALGIALAIGTLFALTIERTRLGLSARAVIMNETLARSLGIDTGR
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCH
VRLVVFMLGAGFAGLAGVLLTPLTSVDPNMGVSWLIGAFMLVMVADASYLALAAACLVFG
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
AAQVLISTFVSPILGSIAVAVLAALVLRISPKGFSRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLLTLDILTTAAILFIVSIGLLAIFGVLKIINFAHGAWLTVGAYCAVVTAKLGLNPWAAL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHH
PLAFAVGAALGGLAEHFIIRPLYRRPLDAILATWGLGIVVGQLITLAFGRDVQLTPNLYA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHH
GTVEILGVDYSAYRLVALGIALAIGTLFALTIERTRLGLSARAVIMNETLARSLGIDTGR
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCH
VRLVVFMLGAGFAGLAGVLLTPLTSVDPNMGVSWLIGAFMLVMVADASYLALAAACLVFG
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
AAQVLISTFVSPILGSIAVAVLAALVLRISPKGFSRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA