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The map label for this gene is pyrC [H]

Identifier: 170750760

GI number: 170750760

Start: 4635870

End: 4637009

Strand: Direct

Name: pyrC [H]

Synonym: Mrad2831_4371

Alternate gene names: 170750760

Gene position: 4635870-4637009 (Clockwise)

Preceding gene: 170750759

Following gene: 170750761

Centisome position: 76.28

GC content: 71.67

Gene sequence:

>1140_bases
GTGCAGCACGACCTCATCCTGAAGGGCGCGCGGGTCATCGACCCGTCGCAGAACCACGACGGGATCTGCGACGTCGCCTT
CGCGGACGGCCGCGTCTCGGGCTTCGGCCGCGACCTTCAGGCGAGCCCCGGCACGCAGGTCCGCGACATGGCCGGCGCCA
TCGTCACCCCGGGCCTGATCGACCTGCACACCCACGTCTACTGGGGCGGCACCTCGCTCGGCATCGACGCCGACGAATTC
TGCCGGACCTCGGGGGTGACCACCTCGGTCGATACCGGCAGCGCCGGCCCCGGCAACTTTGCCGGCTTCCGCAGCCACGT
GATCGAGCGGTCGCAGGCGCGGATCCTCGCCTACCTGCACGTCTCCTTCGCGGGGATCTTCGGCTTCTCGAAGACCATCA
TGGTCGGCGAGAGCGAGGATCCGCGGCTCATGGCACCGCGCGAGGCGGTCGAGGTCGCCGACGCCAACCGGGACGTGATC
GTCGGCATCAAGGTCCGGGTCGGGCGCCACGCCTCGGGCGACCAGGGCACCGCGCCGCTCGACATCGCGCTGCAGGTCGC
CGAGGAGACCGGCCTGCCGCTGATGGCCCATATCGACGAGCCGCCGCCGAGCTACGAGGCGGTGCTGGCCATGCTGCGGC
CCGGCGACGTGCTGACCCACGCGTTCCGGCCGTTCCCGAACTCCCCGATCACGGCCCAGGGCGCCGTGAAGCCGGCGCTC
CGCGAGGCGCGGGCGCGGGGCGTGATCTTCGACATCGGCCACGGCAAGGGCTCGTTCGCCTTCAAGACGGCGCGGGCCAT
GCTGGCCGGCGGCTTCCTGCCCGACACGATCTCGTCCGACGTGCACCAGCTCTGCATCGAGGGGCCGGCCTTCGACCAGG
TCACCACCATGTCGAAGATGCTCTGCCTGGGCATGAGCCTCGACGAGGTCGTCGCCGCCTCCACGGTGAACGCCGCCGTG
GCGCTGAAGCGGATGGAGTACGGGACCCTGAAGGTCGGGGCGCTCGGCGACGCCACGGTGCTGGCGGTGCGGGACGGGGA
GTTCGACTACGTCGACACCCGGGGCGAGCACATGACGGGCGACCGGCGGATCACCGCGGAGGGCGTGGTGCTGCGCGGGG
CGTGGTGGCACCCGGCCTGA

Upstream 100 bases:

>100_bases
CAGGGCGGCGCGCGGTCCCCGAGCGTGGCGGATCCCTGGGTCGCTTCGCTGCGCGCGCGATGACGGGTCGGATTCCCGCG
ACCAACATCTGGAGTCTCTC

Downstream 100 bases:

>100_bases
CCGCGCCGGGATCGCGCCCCGAGGACCTCGGTCCTATCGCATACAAAATATCGACCTTTACAGCCTCTTCGACTGACCGA
TACACTTTCCCGTGAGGGTC

Product: dihydroorotase

Products: NA

Alternate protein names: DHOase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MQHDLILKGARVIDPSQNHDGICDVAFADGRVSGFGRDLQASPGTQVRDMAGAIVTPGLIDLHTHVYWGGTSLGIDADEF
CRTSGVTTSVDTGSAGPGNFAGFRSHVIERSQARILAYLHVSFAGIFGFSKTIMVGESEDPRLMAPREAVEVADANRDVI
VGIKVRVGRHASGDQGTAPLDIALQVAEETGLPLMAHIDEPPPSYEAVLAMLRPGDVLTHAFRPFPNSPITAQGAVKPAL
REARARGVIFDIGHGKGSFAFKTARAMLAGGFLPDTISSDVHQLCIEGPAFDQVTTMSKMLCLGMSLDEVVAASTVNAAV
ALKRMEYGTLKVGALGDATVLAVRDGEFDYVDTRGEHMTGDRRITAEGVVLRGAWWHPA

Sequences:

>Translated_379_residues
MQHDLILKGARVIDPSQNHDGICDVAFADGRVSGFGRDLQASPGTQVRDMAGAIVTPGLIDLHTHVYWGGTSLGIDADEF
CRTSGVTTSVDTGSAGPGNFAGFRSHVIERSQARILAYLHVSFAGIFGFSKTIMVGESEDPRLMAPREAVEVADANRDVI
VGIKVRVGRHASGDQGTAPLDIALQVAEETGLPLMAHIDEPPPSYEAVLAMLRPGDVLTHAFRPFPNSPITAQGAVKPAL
REARARGVIFDIGHGKGSFAFKTARAMLAGGFLPDTISSDVHQLCIEGPAFDQVTTMSKMLCLGMSLDEVVAASTVNAAV
ALKRMEYGTLKVGALGDATVLAVRDGEFDYVDTRGEHMTGDRRITAEGVVLRGAWWHPA
>Mature_379_residues
MQHDLILKGARVIDPSQNHDGICDVAFADGRVSGFGRDLQASPGTQVRDMAGAIVTPGLIDLHTHVYWGGTSLGIDADEF
CRTSGVTTSVDTGSAGPGNFAGFRSHVIERSQARILAYLHVSFAGIFGFSKTIMVGESEDPRLMAPREAVEVADANRDVI
VGIKVRVGRHASGDQGTAPLDIALQVAEETGLPLMAHIDEPPPSYEAVLAMLRPGDVLTHAFRPFPNSPITAQGAVKPAL
REARARGVIFDIGHGKGSFAFKTARAMLAGGFLPDTISSDVHQLCIEGPAFDQVTTMSKMLCLGMSLDEVVAASTVNAAV
ALKRMEYGTLKVGALGDATVLAVRDGEFDYVDTRGEHMTGDRRITAEGVVLRGAWWHPA

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG3964

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Type 2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.3 [H]

Molecular weight: Translated: 40241; Mature: 40241

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHDLILKGARVIDPSQNHDGICDVAFADGRVSGFGRDLQASPGTQVRDMAGAIVTPGLI
CCCCEEECCCEEECCCCCCCCEEEEEEECCEECCCCCCCCCCCCCHHHHHCCHHCCCCEE
DLHTHVYWGGTSLGIDADEFCRTSGVTTSVDTGSAGPGNFAGFRSHVIERSQARILAYLH
EEEEEEEECCCCCCCCHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEEEE
VSFAGIFGFSKTIMVGESEDPRLMAPREAVEVADANRDVIVGIKVRVGRHASGDQGTAPL
HHHHHHHCCCEEEEEECCCCCCEECCHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCC
DIALQVAEETGLPLMAHIDEPPPSYEAVLAMLRPGDVLTHAFRPFPNSPITAQGAVKPAL
EEEEEEHHHCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHH
REARARGVIFDIGHGKGSFAFKTARAMLAGGFLPDTISSDVHQLCIEGPAFDQVTTMSKM
HHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LCLGMSLDEVVAASTVNAAVALKRMEYGTLKVGALGDATVLAVRDGEFDYVDTRGEHMTG
HHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCCCEEECCCCCCCC
DRRITAEGVVLRGAWWHPA
CEEEEECCEEEECCCCCCC
>Mature Secondary Structure
MQHDLILKGARVIDPSQNHDGICDVAFADGRVSGFGRDLQASPGTQVRDMAGAIVTPGLI
CCCCEEECCCEEECCCCCCCCEEEEEEECCEECCCCCCCCCCCCCHHHHHCCHHCCCCEE
DLHTHVYWGGTSLGIDADEFCRTSGVTTSVDTGSAGPGNFAGFRSHVIERSQARILAYLH
EEEEEEEECCCCCCCCHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEEEE
VSFAGIFGFSKTIMVGESEDPRLMAPREAVEVADANRDVIVGIKVRVGRHASGDQGTAPL
HHHHHHHCCCEEEEEECCCCCCEECCHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCC
DIALQVAEETGLPLMAHIDEPPPSYEAVLAMLRPGDVLTHAFRPFPNSPITAQGAVKPAL
EEEEEEHHHCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHH
REARARGVIFDIGHGKGSFAFKTARAMLAGGFLPDTISSDVHQLCIEGPAFDQVTTMSKM
HHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LCLGMSLDEVVAASTVNAAVALKRMEYGTLKVGALGDATVLAVRDGEFDYVDTRGEHMTG
HHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCCCEEECCCCCCCC
DRRITAEGVVLRGAWWHPA
CEEEEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA