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The map label for this gene is regB [H]

Identifier: 170750753

GI number: 170750753

Start: 4626437

End: 4627828

Strand: Reverse

Name: regB [H]

Synonym: Mrad2831_4364

Alternate gene names: 170750753

Gene position: 4627828-4626437 (Counterclockwise)

Preceding gene: 170750765

Following gene: 170750752

Centisome position: 76.14

GC content: 73.13

Gene sequence:

>1392_bases
ATGCCCGATACCGATCTCAGCGGCCTCGGTCGCGACGCGCGACACCTGCGGCTCGACACCTTCGTCCGCCTGCGCTGGCT
CGCCATCACGGGCCAGAGCGCGGCGGTCGTCGGGGCGCAGTTCGGCCTCGGCCTGCCGCTGCCCTTCGGCTGGTGCTTCC
TGGTGATCGCCACCTCGTCCTGGCTGAACCTCGCCCTGCGGATCCGCTTCCCGGCGAGCTACCGGCTCAGCGACGATTCC
GCGGCGCTGCTCCTCGCCTTCGACATCGTGCAGCTCGCGGCCCTGCTGTTCCTCACGGGCGGGCTCCAGAACCCGTTCTC
GCTGCTGTTCCTCGCCCCCGTGCTGATCTCCGCCACCGCCCTGCCGCCCGAGCGGACGCTGGCGCTCGGCCTCCTGGCGG
TGGGCCTCGCGACCCTGCTCGCGCTGGTGCACCGGCCCCTGCCCTGGTTCGCGGACGGTCGGATCGAGCTGCCGTTCCTG
TACGTCTCCGGCGTCTGGACCGCGATCCTGCTCGGCACCGCCTTCACGGGCGTCTACGCGTGGCGGGTGGCCGAGGAGAC
CCGGCTCCTCGCCCAGGCGCTCGCCGCCACCGAGCTGGTGCTCGCCCGCGAGCAGCACCTGTCGCAGCTCGACGGGCTCG
CGGCCGCGGCTGCCCACGAATTGGGCACACCGCTGGGCACGATCATGGTTGTGACCAAGGAGCTGATCCGCCAGCTCGGC
CCCACCGCCTCACCGGCGGTGGCGGAGGATCTCAACCTGCTGCGCGAGCAGGTCGACCGCTGCCGCGGCATCCTCGGCAA
GCTGACCTCCCTCGACGGGGACGGGGCGGGGGCCGGCTTCCTGGAGACGGTGACGTTCAGCCACCTCGTGGAGGAGCTGG
TGGCGCCGCAGCGGGCACTCGGCGCCGCCCTCGCCGTCACCAGCACCGGCGAGGGGCCGGAGCCCGCCTGCCGGCGCAAC
CCGGGCGTCATGTTCGGGCTCGCCAACATCCTCGACAACGCCGTCGACTTCGCCGAGGCCGGCGTCACCGTGGAGGGGCG
CTGGACCCCCGACCGCGTCTGGATCGAGATCCGCGACGACGGGCCGGGCTTCTCCAGCGAGGTGCTGCTGCGGGCGGGCG
AGCCCTACGTCACCACCCGCAGCCACGACCGGCCGCAATCCGGCGGGACCGTGGGGGCCGGGCTCGGCCTCGGGCTGTTC
ATCGCCAAGACCCTGATCGAGCGCTCGGGGGCGCAGCTCGCCCTCATGAACGTCGCGGCGCCGGACGCCCACGGGGCGAT
CGTGCGCGTCTCCTGGGCCCGCCACATCTTCGAGCGCGGCGCCGCGCCGCGACATTCTCCGGAACTCAGTATCCGCGCCC
CCCTGCCACCGCGCGACGCCGTACCTATATGA

Upstream 100 bases:

>100_bases
TCCGGGTCGGCATGCCGGGATTCCCAGCACCGCGTCGTGCGAAGGGAGTCCGCGGGACGCCGCTCCGGCGGCGCCCGTCC
GGCGACGCACGATACAGTCT

Downstream 100 bases:

>100_bases
AGGACAGACCAAGAACCCGACGACGTAAACCCGAAAGGAGTGCCGGATGCTCACGCAGCCCGGGACCTCGGCGGCGACAG
ACCCCGCCGTGATCAACGAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MPDTDLSGLGRDARHLRLDTFVRLRWLAITGQSAAVVGAQFGLGLPLPFGWCFLVIATSSWLNLALRIRFPASYRLSDDS
AALLLAFDIVQLAALLFLTGGLQNPFSLLFLAPVLISATALPPERTLALGLLAVGLATLLALVHRPLPWFADGRIELPFL
YVSGVWTAILLGTAFTGVYAWRVAEETRLLAQALAATELVLAREQHLSQLDGLAAAAAHELGTPLGTIMVVTKELIRQLG
PTASPAVAEDLNLLREQVDRCRGILGKLTSLDGDGAGAGFLETVTFSHLVEELVAPQRALGAALAVTSTGEGPEPACRRN
PGVMFGLANILDNAVDFAEAGVTVEGRWTPDRVWIEIRDDGPGFSSEVLLRAGEPYVTTRSHDRPQSGGTVGAGLGLGLF
IAKTLIERSGAQLALMNVAAPDAHGAIVRVSWARHIFERGAAPRHSPELSIRAPLPPRDAVPI

Sequences:

>Translated_463_residues
MPDTDLSGLGRDARHLRLDTFVRLRWLAITGQSAAVVGAQFGLGLPLPFGWCFLVIATSSWLNLALRIRFPASYRLSDDS
AALLLAFDIVQLAALLFLTGGLQNPFSLLFLAPVLISATALPPERTLALGLLAVGLATLLALVHRPLPWFADGRIELPFL
YVSGVWTAILLGTAFTGVYAWRVAEETRLLAQALAATELVLAREQHLSQLDGLAAAAAHELGTPLGTIMVVTKELIRQLG
PTASPAVAEDLNLLREQVDRCRGILGKLTSLDGDGAGAGFLETVTFSHLVEELVAPQRALGAALAVTSTGEGPEPACRRN
PGVMFGLANILDNAVDFAEAGVTVEGRWTPDRVWIEIRDDGPGFSSEVLLRAGEPYVTTRSHDRPQSGGTVGAGLGLGLF
IAKTLIERSGAQLALMNVAAPDAHGAIVRVSWARHIFERGAAPRHSPELSIRAPLPPRDAVPI
>Mature_462_residues
PDTDLSGLGRDARHLRLDTFVRLRWLAITGQSAAVVGAQFGLGLPLPFGWCFLVIATSSWLNLALRIRFPASYRLSDDSA
ALLLAFDIVQLAALLFLTGGLQNPFSLLFLAPVLISATALPPERTLALGLLAVGLATLLALVHRPLPWFADGRIELPFLY
VSGVWTAILLGTAFTGVYAWRVAEETRLLAQALAATELVLAREQHLSQLDGLAAAAAHELGTPLGTIMVVTKELIRQLGP
TASPAVAEDLNLLREQVDRCRGILGKLTSLDGDGAGAGFLETVTFSHLVEELVAPQRALGAALAVTSTGEGPEPACRRNP
GVMFGLANILDNAVDFAEAGVTVEGRWTPDRVWIEIRDDGPGFSSEVLLRAGEPYVTTRSHDRPQSGGTVGAGLGLGLFI
AKTLIERSGAQLALMNVAAPDAHGAIVRVSWARHIFERGAAPRHSPELSIRAPLPPRDAVPI

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49248; Mature: 49116

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTDLSGLGRDARHLRLDTFVRLRWLAITGQSAAVVGAQFGLGLPLPFGWCFLVIATSS
CCCCCCCCCCCCHHHHHHHHHEEEEEEEEECCCCEEEEHHCCCCCCCHHHHHHHHHHHHH
WLNLALRIRFPASYRLSDDSAALLLAFDIVQLAALLFLTGGLQNPFSLLFLAPVLISATA
HHEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
LPPERTLALGLLAVGLATLLALVHRPLPWFADGRIELPFLYVSGVWTAILLGTAFTGVYA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHH
WRVAEETRLLAQALAATELVLAREQHLSQLDGLAAAAAHELGTPLGTIMVVTKELIRQLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
PTASPAVAEDLNLLREQVDRCRGILGKLTSLDGDGAGAGFLETVTFSHLVEELVAPQRAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
GAALAVTSTGEGPEPACRRNPGVMFGLANILDNAVDFAEAGVTVEGRWTPDRVWIEIRDD
HHEEEEECCCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECC
GPGFSSEVLLRAGEPYVTTRSHDRPQSGGTVGAGLGLGLFIAKTLIERSGAQLALMNVAA
CCCCCCHHHEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
PDAHGAIVRVSWARHIFERGAAPRHSPELSIRAPLPPRDAVPI
CCCCCCEEEEHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
PDTDLSGLGRDARHLRLDTFVRLRWLAITGQSAAVVGAQFGLGLPLPFGWCFLVIATSS
CCCCCCCCCCCHHHHHHHHHEEEEEEEEECCCCEEEEHHCCCCCCCHHHHHHHHHHHHH
WLNLALRIRFPASYRLSDDSAALLLAFDIVQLAALLFLTGGLQNPFSLLFLAPVLISATA
HHEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
LPPERTLALGLLAVGLATLLALVHRPLPWFADGRIELPFLYVSGVWTAILLGTAFTGVYA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHH
WRVAEETRLLAQALAATELVLAREQHLSQLDGLAAAAAHELGTPLGTIMVVTKELIRQLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
PTASPAVAEDLNLLREQVDRCRGILGKLTSLDGDGAGAGFLETVTFSHLVEELVAPQRAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
GAALAVTSTGEGPEPACRRNPGVMFGLANILDNAVDFAEAGVTVEGRWTPDRVWIEIRDD
HHEEEEECCCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECC
GPGFSSEVLLRAGEPYVTTRSHDRPQSGGTVGAGLGLGLFIAKTLIERSGAQLALMNVAA
CCCCCCHHHEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
PDAHGAIVRVSWARHIFERGAAPRHSPELSIRAPLPPRDAVPI
CCCCCCEEEEHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]