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The map label for this gene is glmM

Identifier: 170750726

GI number: 170750726

Start: 4594470

End: 4595813

Strand: Direct

Name: glmM

Synonym: Mrad2831_4337

Alternate gene names: 170750726

Gene position: 4594470-4595813 (Clockwise)

Preceding gene: 170750725

Following gene: 170750728

Centisome position: 75.59

GC content: 70.61

Gene sequence:

>1344_bases
ATGGTGCGCAAGTATTTCGGAACTGACGGCATCCGGGGCCGGGCCAACGGCGTGATCACGCCGGAACTCGCCCTCAAGGT
CGGTCAGGCCGCCGGCCTCGTGTTCCAGCGCGGCGACCACCGCCACCGGGTGGTGATCGGCAAGGACACCCGCCTCTCCG
GCTACATGATCGAGACCGCGCTCGTCGCCGGCTTCACCTCGGTCGGCATGGACGTGCTGCTGCTCGGGCCGGTGCCGACG
CCGGCCGTGGCGATGCTGACCCGCTCCATGCGGGCCGATCTCGGCGTGATGATCTCGGCCTCGCACAACCCGTTCGAGGA
CAACGGCATCAAGCTGTTCGGGCCCGACGGCTTCAAGCTGAACGACGCGATCGAGCACGAGATCGAGGGGCTGATCGACG
CCGACATGCACAAGCGTCTCTCCGGCTCGAACGACCTCGGCCGGGCCAAGCGCATCGAGAGCGTGCACGCCCGCTACATC
GAGTTCGCCAAGCGCACGCTGCCGCGGCAGGTGACCCTGGACGGGCTGCGGGTCGTGGTCGACTGCGCCAACGGCGCGGC
CTACCGGGTCGCCCCCGAGACCCTGTGGGAACTCGGCGCCGAGGTGATCGCCATCGGGACCGAGCCGGACGGGTTCAACA
TCAACCGGGATGTCGGCTCGACCGCGCCCGCGGCCCTGATCGACATGGTGCGCGAGCGCCGGGCCGATATCGGCATCGCG
CTGGACGGCGACGCCGACCGGGTGCTGATCGTGGACGAGAAGGGCCAGGTGGTCGACGGCGACCAGCTCATGGCCGTCGT
GGCGCGCTCCTGGAAGGAGGACGAGCGCCTGACGCAGCCGGGCGTGGTGGCGACGATCATGTCGAATCTCGGCCTGGAGC
GCTTCCTCGGCGGCCTCGGCCTGAGCCTGGCCCGCACGGCGGTGGGGGACCGCTACGTCCTGGAGCACATGCGGGCGCAC
GGCTACAATCTCGGCGGCGAGCAGTCCGGCCACATCATCATGTCGGACTACACGACCACCGGCGACGGCCTCGTGGCCGC
CCTGCAGCTCCTGAGCGTGGTGCAGCGGCAGAACCGGCCCGTGAGCGAGGTCTGCCACTGCTTCGACCCGCTGCCGCAGA
TCCTCAAGAACGTCCGCTACCGGAGCGGCGAGCCCCTGCGCGAGGACAGCGTGGTCAGCGCCATCGAGCACGCCCGCGAG
CGGCTCGGCAATGCCGGCCGCCTCGTGATCCGCCCGTCGGGCACCGAGCCGGTGATCCGCGTCATGGCCGAGGGCGACGA
CCGCGGCCTCGTCAACGCGGTGGTCGACGAGGTGGTCGACGCCGTCACCCGCGCGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGGGAGCACCCCGTTGACTCTGCCGGCCGCTGAGCCGCCGGCGGGCGCGATAACCTGCTAAGCTGTGCCCGGTCCGCGA
GACCGGGCGCCGGAGACGTG

Downstream 100 bases:

>100_bases
GGCCGGAGCCTCGGAGCGGCCCGGCCCGCAATCCCGGCTCCGCCCCCGGGGGGCCGGGCGCGCCGCATCGGGGCGGGATC
GGTCCAGGTCAACCTAGGTC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MVRKYFGTDGIRGRANGVITPELALKVGQAAGLVFQRGDHRHRVVIGKDTRLSGYMIETALVAGFTSVGMDVLLLGPVPT
PAVAMLTRSMRADLGVMISASHNPFEDNGIKLFGPDGFKLNDAIEHEIEGLIDADMHKRLSGSNDLGRAKRIESVHARYI
EFAKRTLPRQVTLDGLRVVVDCANGAAYRVAPETLWELGAEVIAIGTEPDGFNINRDVGSTAPAALIDMVRERRADIGIA
LDGDADRVLIVDEKGQVVDGDQLMAVVARSWKEDERLTQPGVVATIMSNLGLERFLGGLGLSLARTAVGDRYVLEHMRAH
GYNLGGEQSGHIIMSDYTTTGDGLVAALQLLSVVQRQNRPVSEVCHCFDPLPQILKNVRYRSGEPLREDSVVSAIEHARE
RLGNAGRLVIRPSGTEPVIRVMAEGDDRGLVNAVVDEVVDAVTRAAA

Sequences:

>Translated_447_residues
MVRKYFGTDGIRGRANGVITPELALKVGQAAGLVFQRGDHRHRVVIGKDTRLSGYMIETALVAGFTSVGMDVLLLGPVPT
PAVAMLTRSMRADLGVMISASHNPFEDNGIKLFGPDGFKLNDAIEHEIEGLIDADMHKRLSGSNDLGRAKRIESVHARYI
EFAKRTLPRQVTLDGLRVVVDCANGAAYRVAPETLWELGAEVIAIGTEPDGFNINRDVGSTAPAALIDMVRERRADIGIA
LDGDADRVLIVDEKGQVVDGDQLMAVVARSWKEDERLTQPGVVATIMSNLGLERFLGGLGLSLARTAVGDRYVLEHMRAH
GYNLGGEQSGHIIMSDYTTTGDGLVAALQLLSVVQRQNRPVSEVCHCFDPLPQILKNVRYRSGEPLREDSVVSAIEHARE
RLGNAGRLVIRPSGTEPVIRVMAEGDDRGLVNAVVDEVVDAVTRAAA
>Mature_447_residues
MVRKYFGTDGIRGRANGVITPELALKVGQAAGLVFQRGDHRHRVVIGKDTRLSGYMIETALVAGFTSVGMDVLLLGPVPT
PAVAMLTRSMRADLGVMISASHNPFEDNGIKLFGPDGFKLNDAIEHEIEGLIDADMHKRLSGSNDLGRAKRIESVHARYI
EFAKRTLPRQVTLDGLRVVVDCANGAAYRVAPETLWELGAEVIAIGTEPDGFNINRDVGSTAPAALIDMVRERRADIGIA
LDGDADRVLIVDEKGQVVDGDQLMAVVARSWKEDERLTQPGVVATIMSNLGLERFLGGLGLSLARTAVGDRYVLEHMRAH
GYNLGGEQSGHIIMSDYTTTGDGLVAALQLLSVVQRQNRPVSEVCHCFDPLPQILKNVRYRSGEPLREDSVVSAIEHARE
RLGNAGRLVIRPSGTEPVIRVMAEGDDRGLVNAVVDEVVDAVTRAAA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=52.5842696629213, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1788361, Length=457, Percent_Identity=26.6958424507659, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_METRJ (B1M3G3)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001756986.1
- ProteinModelPortal:   B1M3G3
- SMR:   B1M3G3
- GeneID:   6140396
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_4337
- HOGENOM:   HBG644964
- OMA:   WIFPKIS
- ProtClustDB:   PRK14315
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48317; Mature: 48317

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 101-101

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKYFGTDGIRGRANGVITPELALKVGQAAGLVFQRGDHRHRVVIGKDTRLSGYMIETA
CCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCHHHHHH
LVAGFTSVGMDVLLLGPVPTPAVAMLTRSMRADLGVMISASHNPFEDNGIKLFGPDGFKL
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCC
NDAIEHEIEGLIDADMHKRLSGSNDLGRAKRIESVHARYIEFAKRTLPRQVTLDGLRVVV
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEE
DCANGAAYRVAPETLWELGAEVIAIGTEPDGFNINRDVGSTAPAALIDMVRERRADIGIA
ECCCCCEEEECHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEE
LDGDADRVLIVDEKGQVVDGDQLMAVVARSWKEDERLTQPGVVATIMSNLGLERFLGGLG
ECCCCCEEEEECCCCCEECHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHCCHHHHHHHHH
LSLARTAVGDRYVLEHMRAHGYNLGGEQSGHIIMSDYTTTGDGLVAALQLLSVVQRQNRP
HHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCC
VSEVCHCFDPLPQILKNVRYRSGEPLREDSVVSAIEHARERLGNAGRLVIRPSGTEPVIR
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEE
VMAEGDDRGLVNAVVDEVVDAVTRAAA
EEECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRKYFGTDGIRGRANGVITPELALKVGQAAGLVFQRGDHRHRVVIGKDTRLSGYMIETA
CCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCHHHHHH
LVAGFTSVGMDVLLLGPVPTPAVAMLTRSMRADLGVMISASHNPFEDNGIKLFGPDGFKL
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCC
NDAIEHEIEGLIDADMHKRLSGSNDLGRAKRIESVHARYIEFAKRTLPRQVTLDGLRVVV
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEE
DCANGAAYRVAPETLWELGAEVIAIGTEPDGFNINRDVGSTAPAALIDMVRERRADIGIA
ECCCCCEEEECHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEE
LDGDADRVLIVDEKGQVVDGDQLMAVVARSWKEDERLTQPGVVATIMSNLGLERFLGGLG
ECCCCCEEEEECCCCCEECHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHCCHHHHHHHHH
LSLARTAVGDRYVLEHMRAHGYNLGGEQSGHIIMSDYTTTGDGLVAALQLLSVVQRQNRP
HHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCC
VSEVCHCFDPLPQILKNVRYRSGEPLREDSVVSAIEHARERLGNAGRLVIRPSGTEPVIR
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEE
VMAEGDDRGLVNAVVDEVVDAVTRAAA
EEECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA