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The map label for this gene is qseD [H]

Identifier: 170750684

GI number: 170750684

Start: 4545626

End: 4546477

Strand: Direct

Name: qseD [H]

Synonym: Mrad2831_4294

Alternate gene names: 170750684

Gene position: 4545626-4546477 (Clockwise)

Preceding gene: 170750683

Following gene: 170750685

Centisome position: 74.79

GC content: 76.17

Gene sequence:

>852_bases
ATGGAGCTGAAATGGCTCGAGGACTTCCTGAGCCTCGCGCGCACCGGCAGCTTCTCGCGCTCGGCGGTCGAGCGCCACGT
CACCCAGCCGGCCTTCGGCCGCCGCATCCGGGCGCTGGAGGGCTGGCTCGGCGTCGCGCTGGTCGACCGCAGCACCTACC
CGACCGCGCTGACGCCGGAGGGCCGACTGTTCCTGGAGACCGCCGAGGAGACCGTGCGGCGGCTCCACGGCAGCCGCGAC
GCGCTCCGGGACCGGATCCGGCCGCCGCCCCGGACCGTGTCGGTGGCGGCGCTCCACACCCTGGCGCTGACCGTCTTCCC
GCGCTGGTTCCGGGACGTCGAGGCCCGCACCGGGCCGCTCGGCAGCCGGCTGCTGCCCGATGATTTCCACGCCTGCGTGC
AGGCCCTGGCCGAGGGCGGCTACGACCTGCTGCTGACCTACCACCATCCGCTGGTGCCGATCCCCCTGGACCCGGCCGCC
TTCCCGCACCTCGCCATCGGCCGGGACAGCCTCGTGCCGGTGCACCGGCCGGGGCCGGCCGCGGACCGGCCCGGGCTCGG
CTATCCCCGGGACTCGTTCCTGGGCCGGGTCGCGGCGCTGGCCGGTGACGGGGCGGCGGCCGCCCACGTCAACGAGAACG
CCATGGCGGAGGCCCTGAAGTTCATGGTTCTTGAAGGCCACGGCCGCGCCTGGCTGCCCGAGAGCCTCGTCGCCCGCGAA
CTCGCCGACGGCAGCCTCGTGGCGGCCGGGCCGGGCACACCGTTGGAGATCCGGCTCTACCGCCGGGCCGGCCGCGGCGG
CGCGGTCGAGGCGGTCTGGGCCGCGGCCGCCGCCCTGGCGGCCGAACCCTAG

Upstream 100 bases:

>100_bases
CGGCGCGCGGGCCGTGACGGTGCGGCGGGTCGACTACGCCTTCGCGGCCGAGAACCCGCTGGCGGAGCGGCTGCTGGCGC
GGCTCTGAGACCGCCGCGCG

Downstream 100 bases:

>100_bases
GAACCGCCGCACGCCCCGGTGCCGGATCGGCATGGCCGGTGCCGACACGGCATTGGATTCCCGCCCCGCCGCGGCCCATC
AGGGCGTCGCGACGGTCGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MELKWLEDFLSLARTGSFSRSAVERHVTQPAFGRRIRALEGWLGVALVDRSTYPTALTPEGRLFLETAEETVRRLHGSRD
ALRDRIRPPPRTVSVAALHTLALTVFPRWFRDVEARTGPLGSRLLPDDFHACVQALAEGGYDLLLTYHHPLVPIPLDPAA
FPHLAIGRDSLVPVHRPGPAADRPGLGYPRDSFLGRVAALAGDGAAAAHVNENAMAEALKFMVLEGHGRAWLPESLVARE
LADGSLVAAGPGTPLEIRLYRRAGRGGAVEAVWAAAAALAAEP

Sequences:

>Translated_283_residues
MELKWLEDFLSLARTGSFSRSAVERHVTQPAFGRRIRALEGWLGVALVDRSTYPTALTPEGRLFLETAEETVRRLHGSRD
ALRDRIRPPPRTVSVAALHTLALTVFPRWFRDVEARTGPLGSRLLPDDFHACVQALAEGGYDLLLTYHHPLVPIPLDPAA
FPHLAIGRDSLVPVHRPGPAADRPGLGYPRDSFLGRVAALAGDGAAAAHVNENAMAEALKFMVLEGHGRAWLPESLVARE
LADGSLVAAGPGTPLEIRLYRRAGRGGAVEAVWAAAAALAAEP
>Mature_283_residues
MELKWLEDFLSLARTGSFSRSAVERHVTQPAFGRRIRALEGWLGVALVDRSTYPTALTPEGRLFLETAEETVRRLHGSRD
ALRDRIRPPPRTVSVAALHTLALTVFPRWFRDVEARTGPLGSRLLPDDFHACVQALAEGGYDLLLTYHHPLVPIPLDPAA
FPHLAIGRDSLVPVHRPGPAADRPGLGYPRDSFLGRVAALAGDGAAAAHVNENAMAEALKFMVLEGHGRAWLPESLVARE
LADGSLVAAGPGTPLEIRLYRRAGRGGAVEAVWAAAAALAAEP

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=294, Percent_Identity=30.952380952381, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30533; Mature: 30533

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKWLEDFLSLARTGSFSRSAVERHVTQPAFGRRIRALEGWLGVALVDRSTYPTALTPE
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCCEECCC
GRLFLETAEETVRRLHGSRDALRDRIRPPPRTVSVAALHTLALTVFPRWFRDVEARTGPL
CCEEEHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSRLLPDDFHACVQALAEGGYDLLLTYHHPLVPIPLDPAAFPHLAIGRDSLVPVHRPGPA
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCCCCEECCCCCCCCCCCCCCC
ADRPGLGYPRDSFLGRVAALAGDGAAAAHVNENAMAEALKFMVLEGHGRAWLPESLVARE
CCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LADGSLVAAGPGTPLEIRLYRRAGRGGAVEAVWAAAAALAAEP
HCCCCEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELKWLEDFLSLARTGSFSRSAVERHVTQPAFGRRIRALEGWLGVALVDRSTYPTALTPE
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCCEECCC
GRLFLETAEETVRRLHGSRDALRDRIRPPPRTVSVAALHTLALTVFPRWFRDVEARTGPL
CCEEEHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSRLLPDDFHACVQALAEGGYDLLLTYHHPLVPIPLDPAAFPHLAIGRDSLVPVHRPGPA
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCCCCEECCCCCCCCCCCCCCC
ADRPGLGYPRDSFLGRVAALAGDGAAAAHVNENAMAEALKFMVLEGHGRAWLPESLVARE
CCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LADGSLVAAGPGTPLEIRLYRRAGRGGAVEAVWAAAAALAAEP
HCCCCEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]