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The map label for this gene is bphB [H]

Identifier: 170750660

GI number: 170750660

Start: 4520899

End: 4523154

Strand: Reverse

Name: bphB [H]

Synonym: Mrad2831_4270

Alternate gene names: 170750660

Gene position: 4523154-4520899 (Counterclockwise)

Preceding gene: 170750661

Following gene: 170750659

Centisome position: 74.42

GC content: 71.85

Gene sequence:

>2256_bases
TTGAACCTTCGAAGCGGCGCGGCCCCGCGTCTCGACCTGAGCGCGTGCGATCGCGAGCCCATCCACATCGTCGGCAGCGT
CCAGCCGCACGGGTTCCTGCTCGGCCTCGAGGCCCGGTCCCTCACCATCGTCCAGGCGAGCGCCAACGCCCCCGCGGCGG
CTACGGTCGGAACCGTGCTCGACGCGGCCCTGCCCGACCTCGCGGCCGTCGTCCGCCACCATCTCACGGCGGCCGAGCCC
CAGGACGGCGCCCTCTATCTCCGGACCGTGACGCTGGAGACCGGCGGCGGCCGTCAGGCCTACGAGGTCGCGGCTCACCG
GGTCGACGATCTCGTCGTGCTGGAACTGGAGGAGATCGACGCGGCCGCGGCCGAGATCGGCGTCGACGTGCTCACCCCGC
GCCTGCGGGCCTTCGTCGAGCGCCTGCAGACCGCCCGCACCGTCGAGGACCTCTGCCGGTTCGTCGCCGAGGACATCCGC
CAGATCACCGGCCTCGACCGCGCCCTGGTCTACCGGTTCGACCGCGACTGGCACGGCACGGTGCTGGCGGAGGCCGGCAA
CGGCGTCCTGCCCTCCTACCTCGACCTGCGCTTCCCCGCCTCCGACATCCCCGTCCAGGCGCGCGAGCTCTACCGCCGGA
ACCGCCTGCGCATCATCCCCGATGCCGGCTACGTCCCCGTGCCGATCCGGCCGGCCACCACGCCCTCCGGCAAGCCGCTG
GACCTCAGCCAGTCGGTGCTGCGCTCGGTCTCGCCGGTCCATGTCGAGTACATGCGCAACATGGGCACGATGGCGTCCAT
GTCGGTGTCGATCCTCGTGGACGGCGGCCTCTGGGGCCTGATCTCCTGCCACAACCGCACGCCCAAGCGCGTGCCCCTGC
AGGCGCGCAACGCCTGCGACGTGCTCACCCAGATCTTCGCCCTGCAGCTCTCGGCCCGCGAGCGCGGCGCCCAGTCCGAG
AAGCGGCTGGCGCTCGGCGCCGTGCAGGCGCGCCTCCTGGCGTTCATGGCCGAGGAGGACAGCTTCGTCGACGGCCTGCT
CAACCACCCCGACGACGTCCTGGCCCTGGTGGACGCGACCGGCGCCGCGGTGGTGACGGCGGACCGCTGCCGGCTGCTCG
GGGCGACGCCGGCGGAGCGGGAGGTCCGCGCCCTCTACCGGTGGCTGTCCGAGCGCGACGATTCCGAGGAGGTCTTCGTC
TCCGAGGCCCTGTCGGAGGCGTTCCCGGCCGCCGCCGCCTTCGCCGAGCGGGCGAGCGGCCTCCTGGCGATCTCGGTCTC
GAAGAAGTACGCGAGCTACATCCTCTGGTTCAGGCCCGAGGTCGTGCGGACGGTGAAGTGGGGCGGCAATCCCGTGAAGG
CCGTCCGGCCCGATCCGGAGGGCGGACCGGACCGGCTGCACCCGCGCAAGTCGTTCGAGATCTGGAAGGAGACCGTGCAG
GGCCGCTCCCTGCCCTGGTCCGACCCGGAGGTGGAGGCCGCCAAGGACCTGCGCGCCTCGGTGCTCGGCATCGTGCTCCG
CCGGGCCGAGGAGCTCGCCGCCATGAGCGAGGAGCTGCAGCGCTCGAACAAGGAGCTGGAGGCGTTCTCGTACTCGGTCA
GCCACGACCTGCGCGCGCCGTTCCGCCACATCGTCGGCTACGCGAACCTGCTCAAGACCCGCGAGGGCGCCCAGCTCTCC
GACAAGGGCCGGCACTACGTGGAGACGATCATCGAGGCGGCCTTCTCGGCCGGCACCCTGGTCGACAGCCTCCTGAGCTT
CTCGCAGATGGGCCGGCACGCCCTCAACAAGGTCTGGGGCGACATGAACGCCCTGGTCGAGGAGGTCCGCCGGAAGGTCC
TGCGCGACGTCACCCCCGACCGGACCCTCCGCTGGGAGATCGCGCCGCTGGGCCGCGCCTATGCCGACCCCGTCATGCTG
CGGCTCGTCATCGAGAACCTGCTGTCGAACGCCGTGAAGTACACCCGCGGCACCCCGGAGGCGGTGATCGCGATGGGCAG
CCTCCCGCCCCGGGAGGGCGAGGCGGTCTACTTCGTGCGCGACAACGGCGCCGGGTTCGACATGGCCTACGTCGACAAGC
TGTTCGGCGTCTTCCAGCGGCTGCACCGGGTCGAGGAGTTCGAGGGCACCGGCATCGGCCTCGCCAATGTCCGGCGCATC
GTCGAGCGCCACGGCGGGCGGACCTGGGCCGAGGGCAAGCTCGGCGAGGGCGCCACCTTCTACTTCACCCTGCCCATCCG
GGAGGAGGCGCACTGA

Upstream 100 bases:

>100_bases
GCCGTCCCGACCCGTGCTTTAAGCCTATAGGAGCGGCCCGGTTCGGCTGTTAACACGCGTTAAACTCTGCGACTGACCCG
GTGAGGAGGCGAATCCCGGC

Downstream 100 bases:

>100_bases
TGGCGGGACTGAAGCCCATCCTCCTGGTCGAGGACAATCCGAACGACATCGAGCTGACGCTGGCGGCGCTCGAATCGAGC
CAGCTCGCCAACGAGATCGT

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MNLRSGAAPRLDLSACDREPIHIVGSVQPHGFLLGLEARSLTIVQASANAPAAATVGTVLDAALPDLAAVVRHHLTAAEP
QDGALYLRTVTLETGGGRQAYEVAAHRVDDLVVLELEEIDAAAAEIGVDVLTPRLRAFVERLQTARTVEDLCRFVAEDIR
QITGLDRALVYRFDRDWHGTVLAEAGNGVLPSYLDLRFPASDIPVQARELYRRNRLRIIPDAGYVPVPIRPATTPSGKPL
DLSQSVLRSVSPVHVEYMRNMGTMASMSVSILVDGGLWGLISCHNRTPKRVPLQARNACDVLTQIFALQLSARERGAQSE
KRLALGAVQARLLAFMAEEDSFVDGLLNHPDDVLALVDATGAAVVTADRCRLLGATPAEREVRALYRWLSERDDSEEVFV
SEALSEAFPAAAAFAERASGLLAISVSKKYASYILWFRPEVVRTVKWGGNPVKAVRPDPEGGPDRLHPRKSFEIWKETVQ
GRSLPWSDPEVEAAKDLRASVLGIVLRRAEELAAMSEELQRSNKELEAFSYSVSHDLRAPFRHIVGYANLLKTREGAQLS
DKGRHYVETIIEAAFSAGTLVDSLLSFSQMGRHALNKVWGDMNALVEEVRRKVLRDVTPDRTLRWEIAPLGRAYADPVML
RLVIENLLSNAVKYTRGTPEAVIAMGSLPPREGEAVYFVRDNGAGFDMAYVDKLFGVFQRLHRVEEFEGTGIGLANVRRI
VERHGGRTWAEGKLGEGATFYFTLPIREEAH

Sequences:

>Translated_751_residues
MNLRSGAAPRLDLSACDREPIHIVGSVQPHGFLLGLEARSLTIVQASANAPAAATVGTVLDAALPDLAAVVRHHLTAAEP
QDGALYLRTVTLETGGGRQAYEVAAHRVDDLVVLELEEIDAAAAEIGVDVLTPRLRAFVERLQTARTVEDLCRFVAEDIR
QITGLDRALVYRFDRDWHGTVLAEAGNGVLPSYLDLRFPASDIPVQARELYRRNRLRIIPDAGYVPVPIRPATTPSGKPL
DLSQSVLRSVSPVHVEYMRNMGTMASMSVSILVDGGLWGLISCHNRTPKRVPLQARNACDVLTQIFALQLSARERGAQSE
KRLALGAVQARLLAFMAEEDSFVDGLLNHPDDVLALVDATGAAVVTADRCRLLGATPAEREVRALYRWLSERDDSEEVFV
SEALSEAFPAAAAFAERASGLLAISVSKKYASYILWFRPEVVRTVKWGGNPVKAVRPDPEGGPDRLHPRKSFEIWKETVQ
GRSLPWSDPEVEAAKDLRASVLGIVLRRAEELAAMSEELQRSNKELEAFSYSVSHDLRAPFRHIVGYANLLKTREGAQLS
DKGRHYVETIIEAAFSAGTLVDSLLSFSQMGRHALNKVWGDMNALVEEVRRKVLRDVTPDRTLRWEIAPLGRAYADPVML
RLVIENLLSNAVKYTRGTPEAVIAMGSLPPREGEAVYFVRDNGAGFDMAYVDKLFGVFQRLHRVEEFEGTGIGLANVRRI
VERHGGRTWAEGKLGEGATFYFTLPIREEAH
>Mature_751_residues
MNLRSGAAPRLDLSACDREPIHIVGSVQPHGFLLGLEARSLTIVQASANAPAAATVGTVLDAALPDLAAVVRHHLTAAEP
QDGALYLRTVTLETGGGRQAYEVAAHRVDDLVVLELEEIDAAAAEIGVDVLTPRLRAFVERLQTARTVEDLCRFVAEDIR
QITGLDRALVYRFDRDWHGTVLAEAGNGVLPSYLDLRFPASDIPVQARELYRRNRLRIIPDAGYVPVPIRPATTPSGKPL
DLSQSVLRSVSPVHVEYMRNMGTMASMSVSILVDGGLWGLISCHNRTPKRVPLQARNACDVLTQIFALQLSARERGAQSE
KRLALGAVQARLLAFMAEEDSFVDGLLNHPDDVLALVDATGAAVVTADRCRLLGATPAEREVRALYRWLSERDDSEEVFV
SEALSEAFPAAAAFAERASGLLAISVSKKYASYILWFRPEVVRTVKWGGNPVKAVRPDPEGGPDRLHPRKSFEIWKETVQ
GRSLPWSDPEVEAAKDLRASVLGIVLRRAEELAAMSEELQRSNKELEAFSYSVSHDLRAPFRHIVGYANLLKTREGAQLS
DKGRHYVETIIEAAFSAGTLVDSLLSFSQMGRHALNKVWGDMNALVEEVRRKVLRDVTPDRTLRWEIAPLGRAYADPVML
RLVIENLLSNAVKYTRGTPEAVIAMGSLPPREGEAVYFVRDNGAGFDMAYVDKLFGVFQRLHRVEEFEGTGIGLANVRRI
VERHGGRTWAEGKLGEGATFYFTLPIREEAH

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG4251

COG function: function code T; Bacteriophytochrome (light-regulated signal transduction histidine kinase)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=31.4516129032258, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=270, Percent_Identity=25.1851851851852, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=29.9559471365639, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=284, Percent_Identity=23.5915492957746, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=27.9661016949153, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82711; Mature: 82711

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS50109 HIS_KIN ; PS00237 G_PROTEIN_RECEP_F1_1 ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRSGAAPRLDLSACDREPIHIVGSVQPHGFLLGLEARSLTIVQASANAPAAATVGTVL
CCCCCCCCCCCCHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHH
DAALPDLAAVVRHHLTAAEPQDGALYLRTVTLETGGGRQAYEVAAHRVDDLVVLELEEID
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHH
AAAAEIGVDVLTPRLRAFVERLQTARTVEDLCRFVAEDIRQITGLDRALVYRFDRDWHGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCE
VLAEAGNGVLPSYLDLRFPASDIPVQARELYRRNRLRIIPDAGYVPVPIRPATTPSGKPL
EEEECCCCCCCCHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCCCC
DLSQSVLRSVSPVHVEYMRNMGTMASMSVSILVDGGLWGLISCHNRTPKRVPLQARNACD
CHHHHHHHCCCCHHHHHHHCCCCHHHCEEEEEEECCCEEEEEECCCCCCCCCCCCCHHHH
VLTQIFALQLSARERGAQSEKRLALGAVQARLLAFMAEEDSFVDGLLNHPDDVLALVDAT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHEEEEECC
GAAVVTADRCRLLGATPAEREVRALYRWLSERDDSEEVFVSEALSEAFPAAAAFAERASG
CCEEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
LLAISVSKKYASYILWFRPEVVRTVKWGGNPVKAVRPDPEGGPDRLHPRKSFEIWKETVQ
EEEEEECHHHHHEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GRSLPWSDPEVEAAKDLRASVLGIVLRRAEELAAMSEELQRSNKELEAFSYSVSHDLRAP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FRHIVGYANLLKTREGAQLSDKGRHYVETIIEAAFSAGTLVDSLLSFSQMGRHALNKVWG
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMNALVEEVRRKVLRDVTPDRTLRWEIAPLGRAYADPVMLRLVIENLLSNAVKYTRGTPE
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AVIAMGSLPPREGEAVYFVRDNGAGFDMAYVDKLFGVFQRLHRVEEFEGTGIGLANVRRI
HEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VERHGGRTWAEGKLGEGATFYFTLPIREEAH
HHHCCCCEECCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MNLRSGAAPRLDLSACDREPIHIVGSVQPHGFLLGLEARSLTIVQASANAPAAATVGTVL
CCCCCCCCCCCCHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHH
DAALPDLAAVVRHHLTAAEPQDGALYLRTVTLETGGGRQAYEVAAHRVDDLVVLELEEID
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHH
AAAAEIGVDVLTPRLRAFVERLQTARTVEDLCRFVAEDIRQITGLDRALVYRFDRDWHGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCE
VLAEAGNGVLPSYLDLRFPASDIPVQARELYRRNRLRIIPDAGYVPVPIRPATTPSGKPL
EEEECCCCCCCCHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCCCC
DLSQSVLRSVSPVHVEYMRNMGTMASMSVSILVDGGLWGLISCHNRTPKRVPLQARNACD
CHHHHHHHCCCCHHHHHHHCCCCHHHCEEEEEEECCCEEEEEECCCCCCCCCCCCCHHHH
VLTQIFALQLSARERGAQSEKRLALGAVQARLLAFMAEEDSFVDGLLNHPDDVLALVDAT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHEEEEECC
GAAVVTADRCRLLGATPAEREVRALYRWLSERDDSEEVFVSEALSEAFPAAAAFAERASG
CCEEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
LLAISVSKKYASYILWFRPEVVRTVKWGGNPVKAVRPDPEGGPDRLHPRKSFEIWKETVQ
EEEEEECHHHHHEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GRSLPWSDPEVEAAKDLRASVLGIVLRRAEELAAMSEELQRSNKELEAFSYSVSHDLRAP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FRHIVGYANLLKTREGAQLSDKGRHYVETIIEAAFSAGTLVDSLLSFSQMGRHALNKVWG
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMNALVEEVRRKVLRDVTPDRTLRWEIAPLGRAYADPVMLRLVIENLLSNAVKYTRGTPE
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AVIAMGSLPPREGEAVYFVRDNGAGFDMAYVDKLFGVFQRLHRVEEFEGTGIGLANVRRI
HEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VERHGGRTWAEGKLGEGATFYFTLPIREEAH
HHHCCCCEECCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]