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The map label for this gene is yciR [C]

Identifier: 170750583

GI number: 170750583

Start: 4442214

End: 4444325

Strand: Reverse

Name: yciR [C]

Synonym: Mrad2831_4193

Alternate gene names: 170750583

Gene position: 4444325-4442214 (Counterclockwise)

Preceding gene: 170750585

Following gene: 170750582

Centisome position: 73.12

GC content: 72.35

Gene sequence:

>2112_bases
ATGAACAGTGGGACGGTCGCGCTGCGGGAGAAGGCGAAGCTCCTCGACACCGTTCTCGACGCCATGGATCAGGGGCTGAT
GATGATCGACGCCGACGGCGTCGTTCAAGTCTGTAATGCCCGCGCCCTGGCGCTGCTCGACCTGCCGCTGGCCCTGATGC
GGTCCCGCCCGACCTTCGAGGCCGTCCGGCAATACCAGATCGCGCAGGGGGAGTTCGGGAAGGCGAGCGAAGCCCTGCAG
CGCTGGGTCGCCGACAGCGGCCTGGAGCGCCGCGCCCACACCTACGAGCGCGAGCGCCCCAACGGGACCGTGCTGGAGAT
CCGCACCGTGCCGCTGCCCGACGGCGGGGCGGTGCGGACCTTCACGGACATCACCGCGCGCAAGCGGGCCGAGGAGACGC
TGCAGGTCAGCGAGACGCGCCTCGCCCTGGCGCAGGACGCGGGCAGCGACGGGCTCTGGGACTGCGATCTCACGACCGGG
GAGGCGTGGTCCTCCGACCGCTGGTGGGGGGTTCTGGGCTACGAGCCCGGCGAACTGGCGAGCCACGCGCGGACGTGGCG
GGCGCTGCTCCACCCGGAGGATGCGGGCGCGGCCGAGCGGGCCCTGGTCGAGCACCTGAGCGGGCGGGCGCCGACCTACG
CGTCCGAGCATCGCATGCGCCGCAAGGACGGCTCCTGGGCCTGGATGATGACGCGCGGCAAGGTGGTGGCGCGCGCCGCC
GACGGCCGCGCGCTGCGCTTCATCGGCACCCAGATCGACATCACCGCGCGCAAGGCCGCCGAGGGGCAGGTCGCCCACAT
GGCGCGCCACGACGGCCTCACCGACCTGCCCAACCGCGCCCTGTTCTACGAGCGGCTGGAGATCCGGCTCGCCGACCTGC
ACCTGAACGGCGGCGCCTGCGCGGTGCTGTGCCTCGACCTCGACCGCTTCAAGACCGTCAACGACAGCCTCGGCCACGCG
GCCGGGGACTTCCTGCTCCGGGCGGTGGCCCATCGGATCCGCGCGGTGCTGCGGGCCGACGACATGGTGGCGCGCCTCGG
CGGCGACGAGTTCGCCGTGCTGGTGGCCGATGCGGACGACCCCGCCCGCGCGGAGACCTTGGCGGCCCGCCTGATCGCGG
CCGTCCAGGCGCCGATCCCCTTCGGCAAGCGGCGGCTGAAGGTGGGCCTGAGCGTCGGCATCGCCCAGGCGCCCAGCCAC
GGCTTCGACAGCGAGACGCTGTTCCGCCGCGCCGATCTCGCCCTCCACCGGGCGAAGACCGAAGGCCGGAACACCCACCG
GGTGTTCGAGCCCGCGATGGACGAGGCCGAGGCGGCCCGGCGCGACCTGGAGCGCGACCTGCGCCAAGCGATCGAGGGCG
ACGAGCTCATCCTGTACTATCAGCCGCAGGTGAGTACCGGCACCGGCCGGCTGCTCGGGTTCGAGGCGCTCGTGCGCTGG
GAGCATCCGACCCGCGGCCTCGTGCCGCCGAATGCCTTCATCCCCCTGGCGGAGGAGAGCGGGCTGATCCTGCCGCTGGG
CGAGTGGGTGCTCCGCGCCGCCTGCCGGGAGGCGGCCCGCTGGGCGCACCCGCTGAAGGTCGCGGTGAACCTGTCGCCGC
GCCAGTTCCAGCAGGCGGATCTGCCCGAGCGCGTCCTGGCGATCCTGACCGAGACGGGCCTGGCGCCGACGCGGCTCGAA
CTCGAGATCACCGAGACCCTGATCATCAACGACATGGCGCGGGCACTCGGCATCCTGCGCCGTCTGAAGGCTTTCGGCGT
GTCCATCGCGATGGACGATTTCGGCACCGGCTACTCGTCGCTCGCGACGCTGCAGGCCTTCCCCTTCGACAAGATCAAGA
TCGACCGGTCCTTCGTGGGCCATGTCGAGGTCAGCCCGCAGGCGGCGGTGATCGTGCGGGCGGTTCTGGGGCTCGGCCGC
AGCCTCGGGATGAGTGTCGTGGCGGAGGGCGTCGAGACGGACGCGCAGATGCGCTTCCTGGCCGCGGAAGCGTGCGACGA
GGCCCAGGGCTACCTGATCAGCAAGCCGCAGCCGATCGAGCGGTTCGCCGAGCAGATCGACGCGCCCGAAACCTTCGTGC
CGCCCGGCCGCCCCGACGCGGCCGTCGCCTGA

Upstream 100 bases:

>100_bases
AAAGAATCCGGAAAGCTCCCCGATGGTACCGTCCGCGCCGGTGGGAGCTCGCACCGTCCAGCAGAATGTTCGCTCAGGCG
GACGATTGGGATCCCCGGGT

Downstream 100 bases:

>100_bases
GGCGCGCCGCGCCGCTCCGGCGGCCGGACGACAGCCCGAACGCCCGGACGATCGTCGCGGTCGCGGCGCGGGCCCCGGCG
GCGGCCGTGCCGCCGCCTCT

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 703; Mature: 703

Protein sequence:

>703_residues
MNSGTVALREKAKLLDTVLDAMDQGLMMIDADGVVQVCNARALALLDLPLALMRSRPTFEAVRQYQIAQGEFGKASEALQ
RWVADSGLERRAHTYERERPNGTVLEIRTVPLPDGGAVRTFTDITARKRAEETLQVSETRLALAQDAGSDGLWDCDLTTG
EAWSSDRWWGVLGYEPGELASHARTWRALLHPEDAGAAERALVEHLSGRAPTYASEHRMRRKDGSWAWMMTRGKVVARAA
DGRALRFIGTQIDITARKAAEGQVAHMARHDGLTDLPNRALFYERLEIRLADLHLNGGACAVLCLDLDRFKTVNDSLGHA
AGDFLLRAVAHRIRAVLRADDMVARLGGDEFAVLVADADDPARAETLAARLIAAVQAPIPFGKRRLKVGLSVGIAQAPSH
GFDSETLFRRADLALHRAKTEGRNTHRVFEPAMDEAEAARRDLERDLRQAIEGDELILYYQPQVSTGTGRLLGFEALVRW
EHPTRGLVPPNAFIPLAEESGLILPLGEWVLRAACREAARWAHPLKVAVNLSPRQFQQADLPERVLAILTETGLAPTRLE
LEITETLIINDMARALGILRRLKAFGVSIAMDDFGTGYSSLATLQAFPFDKIKIDRSFVGHVEVSPQAAVIVRAVLGLGR
SLGMSVVAEGVETDAQMRFLAAEACDEAQGYLISKPQPIERFAEQIDAPETFVPPGRPDAAVA

Sequences:

>Translated_703_residues
MNSGTVALREKAKLLDTVLDAMDQGLMMIDADGVVQVCNARALALLDLPLALMRSRPTFEAVRQYQIAQGEFGKASEALQ
RWVADSGLERRAHTYERERPNGTVLEIRTVPLPDGGAVRTFTDITARKRAEETLQVSETRLALAQDAGSDGLWDCDLTTG
EAWSSDRWWGVLGYEPGELASHARTWRALLHPEDAGAAERALVEHLSGRAPTYASEHRMRRKDGSWAWMMTRGKVVARAA
DGRALRFIGTQIDITARKAAEGQVAHMARHDGLTDLPNRALFYERLEIRLADLHLNGGACAVLCLDLDRFKTVNDSLGHA
AGDFLLRAVAHRIRAVLRADDMVARLGGDEFAVLVADADDPARAETLAARLIAAVQAPIPFGKRRLKVGLSVGIAQAPSH
GFDSETLFRRADLALHRAKTEGRNTHRVFEPAMDEAEAARRDLERDLRQAIEGDELILYYQPQVSTGTGRLLGFEALVRW
EHPTRGLVPPNAFIPLAEESGLILPLGEWVLRAACREAARWAHPLKVAVNLSPRQFQQADLPERVLAILTETGLAPTRLE
LEITETLIINDMARALGILRRLKAFGVSIAMDDFGTGYSSLATLQAFPFDKIKIDRSFVGHVEVSPQAAVIVRAVLGLGR
SLGMSVVAEGVETDAQMRFLAAEACDEAQGYLISKPQPIERFAEQIDAPETFVPPGRPDAAVA
>Mature_703_residues
MNSGTVALREKAKLLDTVLDAMDQGLMMIDADGVVQVCNARALALLDLPLALMRSRPTFEAVRQYQIAQGEFGKASEALQ
RWVADSGLERRAHTYERERPNGTVLEIRTVPLPDGGAVRTFTDITARKRAEETLQVSETRLALAQDAGSDGLWDCDLTTG
EAWSSDRWWGVLGYEPGELASHARTWRALLHPEDAGAAERALVEHLSGRAPTYASEHRMRRKDGSWAWMMTRGKVVARAA
DGRALRFIGTQIDITARKAAEGQVAHMARHDGLTDLPNRALFYERLEIRLADLHLNGGACAVLCLDLDRFKTVNDSLGHA
AGDFLLRAVAHRIRAVLRADDMVARLGGDEFAVLVADADDPARAETLAARLIAAVQAPIPFGKRRLKVGLSVGIAQAPSH
GFDSETLFRRADLALHRAKTEGRNTHRVFEPAMDEAEAARRDLERDLRQAIEGDELILYYQPQVSTGTGRLLGFEALVRW
EHPTRGLVPPNAFIPLAEESGLILPLGEWVLRAACREAARWAHPLKVAVNLSPRQFQQADLPERVLAILTETGLAPTRLE
LEITETLIINDMARALGILRRLKAFGVSIAMDDFGTGYSSLATLQAFPFDKIKIDRSFVGHVEVSPQAAVIVRAVLGLGR
SLGMSVVAEGVETDAQMRFLAAEACDEAQGYLISKPQPIERFAEQIDAPETFVPPGRPDAAVA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=453, Percent_Identity=37.7483443708609, Blast_Score=316, Evalue=3e-87,
Organism=Escherichia coli, GI87081921, Length=476, Percent_Identity=33.6134453781513, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI226510982, Length=419, Percent_Identity=33.1742243436754, Blast_Score=215, Evalue=9e-57,
Organism=Escherichia coli, GI1786507, Length=272, Percent_Identity=35.6617647058824, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=35.4581673306773, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081845, Length=237, Percent_Identity=38.3966244725738, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=38.1742738589212, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790496, Length=253, Percent_Identity=32.4110671936759, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081743, Length=248, Percent_Identity=34.2741935483871, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788381, Length=448, Percent_Identity=28.3482142857143, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI87081980, Length=272, Percent_Identity=30.8823529411765, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1788849, Length=238, Percent_Identity=34.8739495798319, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=31.404958677686, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=34.7305389221557, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87081881, Length=226, Percent_Identity=32.7433628318584, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693134, Length=187, Percent_Identity=33.6898395721925, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081977, Length=204, Percent_Identity=28.4313725490196, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787802, Length=185, Percent_Identity=30.8108108108108, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=31.2138728323699, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=35.5421686746988, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=124, Percent_Identity=34.6774193548387, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=31.547619047619, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787410, Length=224, Percent_Identity=27.6785714285714, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=30.0613496932515, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=32.9113924050633, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 77062; Mature: 77062

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSGTVALREKAKLLDTVLDAMDQGLMMIDADGVVQVCNARALALLDLPLALMRSRPTFE
CCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCEEHHHHHHHHHCCCCCHH
AVRQYQIAQGEFGKASEALQRWVADSGLERRAHTYERERPNGTVLEIRTVPLPDGGAVRT
HHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEE
FTDITARKRAEETLQVSETRLALAQDAGSDGLWDCDLTTGEAWSSDRWWGVLGYEPGELA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCHHHH
SHARTWRALLHPEDAGAAERALVEHLSGRAPTYASEHRMRRKDGSWAWMMTRGKVVARAA
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEECCEEEEEEC
DGRALRFIGTQIDITARKAAEGQVAHMARHDGLTDLPNRALFYERLEIRLADLHLNGGAC
CCCEEEEECCEEEEEEHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHEEEEEEEEECCCEE
AVLCLDLDRFKTVNDSLGHAAGDFLLRAVAHRIRAVLRADDMVARLGGDEFAVLVADADD
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
PARAETLAARLIAAVQAPIPFGKRRLKVGLSVGIAQAPSHGFDSETLFRRADLALHRAKT
CHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECEECCCCCCCCHHHHHHHHHHHHHHHHC
EGRNTHRVFEPAMDEAEAARRDLERDLRQAIEGDELILYYQPQVSTGTGRLLGFEALVRW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEHHHHEEE
EHPTRGLVPPNAFIPLAEESGLILPLGEWVLRAACREAARWAHPLKVAVNLSPRQFQQAD
CCCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCC
LPERVLAILTETGLAPTRLELEITETLIINDMARALGILRRLKAFGVSIAMDDFGTGYSS
CHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHH
LATLQAFPFDKIKIDRSFVGHVEVSPQAAVIVRAVLGLGRSLGMSVVAEGVETDAQMRFL
HHHHHCCCCCCEEECCCEECEEEECCHHHHHHHHHHHCCHHHCHHHHHHCCCCHHHHHHH
AAEACDEAQGYLISKPQPIERFAEQIDAPETFVPPGRPDAAVA
HHHHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNSGTVALREKAKLLDTVLDAMDQGLMMIDADGVVQVCNARALALLDLPLALMRSRPTFE
CCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCEEHHHHHHHHHCCCCCHH
AVRQYQIAQGEFGKASEALQRWVADSGLERRAHTYERERPNGTVLEIRTVPLPDGGAVRT
HHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEE
FTDITARKRAEETLQVSETRLALAQDAGSDGLWDCDLTTGEAWSSDRWWGVLGYEPGELA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCHHHH
SHARTWRALLHPEDAGAAERALVEHLSGRAPTYASEHRMRRKDGSWAWMMTRGKVVARAA
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEECCEEEEEEC
DGRALRFIGTQIDITARKAAEGQVAHMARHDGLTDLPNRALFYERLEIRLADLHLNGGAC
CCCEEEEECCEEEEEEHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHEEEEEEEEECCCEE
AVLCLDLDRFKTVNDSLGHAAGDFLLRAVAHRIRAVLRADDMVARLGGDEFAVLVADADD
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
PARAETLAARLIAAVQAPIPFGKRRLKVGLSVGIAQAPSHGFDSETLFRRADLALHRAKT
CHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECEECCCCCCCCHHHHHHHHHHHHHHHHC
EGRNTHRVFEPAMDEAEAARRDLERDLRQAIEGDELILYYQPQVSTGTGRLLGFEALVRW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEHHHHEEE
EHPTRGLVPPNAFIPLAEESGLILPLGEWVLRAACREAARWAHPLKVAVNLSPRQFQQAD
CCCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCC
LPERVLAILTETGLAPTRLELEITETLIINDMARALGILRRLKAFGVSIAMDDFGTGYSS
CHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHH
LATLQAFPFDKIKIDRSFVGHVEVSPQAAVIVRAVLGLGRSLGMSVVAEGVETDAQMRFL
HHHHHCCCCCCEEECCCEECEEEECCHHHHHHHHHHHCCHHHCHHHHHHCCCCHHHHHHH
AAEACDEAQGYLISKPQPIERFAEQIDAPETFVPPGRPDAAVA
HHHHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]