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The map label for this gene is ttuB [H]

Identifier: 170750534

GI number: 170750534

Start: 4399859

End: 4401184

Strand: Reverse

Name: ttuB [H]

Synonym: Mrad2831_4141

Alternate gene names: 170750534

Gene position: 4401184-4399859 (Counterclockwise)

Preceding gene: 170750537

Following gene: 170750533

Centisome position: 72.41

GC content: 69.0

Gene sequence:

>1326_bases
ATGGCGCAAGGGCAGCAGTCCCGAGCTCCGGCCCACGCGGTCGACGAGCGGAACCTTCATCGCAAGATGATGCGGCGGAT
CCTGCCGTTCCTCTTCGTGTGCTACGTGGTCAGCTACCTGGACCGCGTGAATGTCGGCTTCGCCGCGCTCACGATGAACG
CGCATATCGGGCTCACCGCGACGTCGTTCGGCATCGGCGCCGGGCTGTTCTTCCTCGGCTATTTCCTCGCCGAGATCCCC
AGCAACCTGATCATGATGCGTGTCGGGGCCCGGCTCTGGATCGCCCGGATCATGATCACCTGGGGCCTCGTCTCGGCGGC
GACGGCCTTCGTGACCGGGCCGATCCAGTTCGGCATCGCCCGGTTCCTCCTCGGCCTCGGCGAGGCCGGGTTCGTGCCGG
GCGTCTTCCTCTACCTGAGTTTCTGGTTCCCCTCCGCCGTGCGCGCGCGGGCCACCTCTCTCTTCCTGCTCGGTATCCCG
GTCGCCAACATCGTCGGCTCGCCGATCTCCGGCGCGCTGGTGCAGATCGAAGGCTTCGGCCTCGTGGGATGGCAGTGGCT
CCTCATCCTCGAAGCCCTGCCGGCGGTGATCCTCGGCATCGTCTGCCTCTTCGTCCTCACCGACCGGCCGGAGAAGGCGC
AGTGGCTCACGCCCGCGGAGCGTGACGTCCTCGTCGCCACGCTCGCGGCGGAGAAGGCGGCCATCGAGAAGAAGCATCCC
ATGACCCTGGCGCAGGCCCTGCGGAACTGGCGGGTGCTGACGCTGGCGGCGATCAATTTCTGCGCGATCATCGGCTCCCT
CGGCGTTGGCCTGTGGCTGCCGCAGATGATCAAGCAGCTCGGGCTCGCGAGCTCGGTGGTCGGGGTCGTCGCCGCCATTC
CCTATGTCTGCGGCGCGGTGGCGATGGTGGTGTGGGGCCGCGTCTCCGACCGGGGCGGTGACCGCACCATCTATCCGGCC
CTGTCCCTGGCTCTCGGTGCCGTCGGCCTGACCGCGAGCACCCTGACCCCGACACCGGGCCTGACCATCGTGGCGCTCTG
CGTCGCGGTGATGGGCATCAACTCGTACACGGCGACCTTCTGGGCCGTGCCCTCGGGCTTCCTCACCGGTCGCGCCGCGG
CGGGCGGGATCGCGATGATCGTCTCGATCGGCAATCTCGGCGGCTTCGCCGGCCCGTACCTGATCGGCGTGATGCGCGAA
CTGTCCGGGGGATTCACCGCGCCGCTGCTGGCGGTCGGCGGGATCCTGCTCCTCGGCGCCCTGATGATGCTGGCCCTGGG
GCGGCAGATCCGGCGGGACACAATCGCCGTCGCGGTCCCGGCGTGA

Upstream 100 bases:

>100_bases
CCGTGACGGGCCGCTTCCACGACATCGTTGACAACCGCCGCCGCGTGATGGATTAAAAACGAAACGCCGTTTCAAAACTG
GCGATTCGGGAGTGGACGTC

Downstream 100 bases:

>100_bases
CCGCCATGATCCCGCCTCTCCCCTCCGGCCCGACGGTGACCTCGCTGACCGCGGCCTTCTGCGCCGAGCTGCGCGCGCGG
GGCTTCGCGGGCGACCTGAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MAQGQQSRAPAHAVDERNLHRKMMRRILPFLFVCYVVSYLDRVNVGFAALTMNAHIGLTATSFGIGAGLFFLGYFLAEIP
SNLIMMRVGARLWIARIMITWGLVSAATAFVTGPIQFGIARFLLGLGEAGFVPGVFLYLSFWFPSAVRARATSLFLLGIP
VANIVGSPISGALVQIEGFGLVGWQWLLILEALPAVILGIVCLFVLTDRPEKAQWLTPAERDVLVATLAAEKAAIEKKHP
MTLAQALRNWRVLTLAAINFCAIIGSLGVGLWLPQMIKQLGLASSVVGVVAAIPYVCGAVAMVVWGRVSDRGGDRTIYPA
LSLALGAVGLTASTLTPTPGLTIVALCVAVMGINSYTATFWAVPSGFLTGRAAAGGIAMIVSIGNLGGFAGPYLIGVMRE
LSGGFTAPLLAVGGILLLGALMMLALGRQIRRDTIAVAVPA

Sequences:

>Translated_441_residues
MAQGQQSRAPAHAVDERNLHRKMMRRILPFLFVCYVVSYLDRVNVGFAALTMNAHIGLTATSFGIGAGLFFLGYFLAEIP
SNLIMMRVGARLWIARIMITWGLVSAATAFVTGPIQFGIARFLLGLGEAGFVPGVFLYLSFWFPSAVRARATSLFLLGIP
VANIVGSPISGALVQIEGFGLVGWQWLLILEALPAVILGIVCLFVLTDRPEKAQWLTPAERDVLVATLAAEKAAIEKKHP
MTLAQALRNWRVLTLAAINFCAIIGSLGVGLWLPQMIKQLGLASSVVGVVAAIPYVCGAVAMVVWGRVSDRGGDRTIYPA
LSLALGAVGLTASTLTPTPGLTIVALCVAVMGINSYTATFWAVPSGFLTGRAAAGGIAMIVSIGNLGGFAGPYLIGVMRE
LSGGFTAPLLAVGGILLLGALMMLALGRQIRRDTIAVAVPA
>Mature_440_residues
AQGQQSRAPAHAVDERNLHRKMMRRILPFLFVCYVVSYLDRVNVGFAALTMNAHIGLTATSFGIGAGLFFLGYFLAEIPS
NLIMMRVGARLWIARIMITWGLVSAATAFVTGPIQFGIARFLLGLGEAGFVPGVFLYLSFWFPSAVRARATSLFLLGIPV
ANIVGSPISGALVQIEGFGLVGWQWLLILEALPAVILGIVCLFVLTDRPEKAQWLTPAERDVLVATLAAEKAAIEKKHPM
TLAQALRNWRVLTLAAINFCAIIGSLGVGLWLPQMIKQLGLASSVVGVVAAIPYVCGAVAMVVWGRVSDRGGDRTIYPAL
SLALGAVGLTASTLTPTPGLTIVALCVAVMGINSYTATFWAVPSGFLTGRAAAGGIAMIVSIGNLGGFAGPYLIGVMREL
SGGFTAPLLAVGGILLLGALMMLALGRQIRRDTIAVAVPA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=422, Percent_Identity=36.9668246445498, Blast_Score=248, Evalue=8e-67,
Organism=Escherichia coli, GI2367379, Length=444, Percent_Identity=25.9009009009009, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789152, Length=445, Percent_Identity=24.0449438202247, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082320, Length=437, Percent_Identity=23.3409610983982, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789515, Length=448, Percent_Identity=24.1071428571429, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786229, Length=461, Percent_Identity=25.8134490238612, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=261, Percent_Identity=25.6704980842912, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI32565914, Length=261, Percent_Identity=25.6704980842912, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193205400, Length=356, Percent_Identity=24.1573033707865, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=298, Percent_Identity=24.1610738255034, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321698, Length=387, Percent_Identity=22.9974160206718, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=158, Percent_Identity=27.8481012658228, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319876, Length=208, Percent_Identity=25.9615384615385, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46489; Mature: 46358

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQGQQSRAPAHAVDERNLHRKMMRRILPFLFVCYVVSYLDRVNVGFAALTMNAHIGLTA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEE
TSFGIGAGLFFLGYFLAEIPSNLIMMRVGARLWIARIMITWGLVSAATAFVTGPIQFGIA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RFLLGLGEAGFVPGVFLYLSFWFPSAVRARATSLFLLGIPVANIVGSPISGALVQIEGFG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCEEEEECCC
LVGWQWLLILEALPAVILGIVCLFVLTDRPEKAQWLTPAERDVLVATLAAEKAAIEKKHP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
MTLAQALRNWRVLTLAAINFCAIIGSLGVGLWLPQMIKQLGLASSVVGVVAAIPYVCGAV
HHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
AMVVWGRVSDRGGDRTIYPALSLALGAVGLTASTLTPTPGLTIVALCVAVMGINSYTATF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHE
WAVPSGFLTGRAAAGGIAMIVSIGNLGGFAGPYLIGVMRELSGGFTAPLLAVGGILLLGA
EECCCCHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LMMLALGRQIRRDTIAVAVPA
HHHHHHHHHHHHCEEEEEECC
>Mature Secondary Structure 
AQGQQSRAPAHAVDERNLHRKMMRRILPFLFVCYVVSYLDRVNVGFAALTMNAHIGLTA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEE
TSFGIGAGLFFLGYFLAEIPSNLIMMRVGARLWIARIMITWGLVSAATAFVTGPIQFGIA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RFLLGLGEAGFVPGVFLYLSFWFPSAVRARATSLFLLGIPVANIVGSPISGALVQIEGFG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCEEEEECCC
LVGWQWLLILEALPAVILGIVCLFVLTDRPEKAQWLTPAERDVLVATLAAEKAAIEKKHP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
MTLAQALRNWRVLTLAAINFCAIIGSLGVGLWLPQMIKQLGLASSVVGVVAAIPYVCGAV
HHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
AMVVWGRVSDRGGDRTIYPALSLALGAVGLTASTLTPTPGLTIVALCVAVMGINSYTATF
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHE
WAVPSGFLTGRAAAGGIAMIVSIGNLGGFAGPYLIGVMRELSGGFTAPLLAVGGILLLGA
EECCCCHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LMMLALGRQIRRDTIAVAVPA
HHHHHHHHHHHHCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]