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The map label for this gene is mnmG

Identifier: 170750484

GI number: 170750484

Start: 4342814

End: 4344715

Strand: Direct

Name: mnmG

Synonym: Mrad2831_4091

Alternate gene names: 170750484

Gene position: 4342814-4344715 (Clockwise)

Preceding gene: 170750482

Following gene: 170750485

Centisome position: 71.45

GC content: 74.66

Gene sequence:

>1902_bases
ATGCTCACCACCTCCTCCGCACGGTTCGACGTCGCGGTCGTCGGCGGCGGCCATGCCGGCGTCGAGGCCGCCGCCGCCGC
CGCGCGCTGCGGCGCGCGCACCGCGCTGGTCACCCACGATCCCGCGACGATCGGCGCGATGTCCTGCAACCCGGCGATCG
GCGGCCTCGGCAAGGGCCACCTCGTCCGCGAGGTCGATGCCCTGGACGGGCTGATGGGCCGAGTCGCCGACGCGGCCGGC
ATCCAGTTCCGCCTGCTCAACCGCCGCAAGGGACCGGCGGTGCGCGGTCCGCGCACCCAGGCCGACCGCAAGCTCTACGC
GGCCGCCATGCAGACCGCCGTGGCCGAGACCGCCGGCCTCACCGTGGTCGCGGGCGCGTGCGAGGATCTGGCCTTCGACG
CTGAGGGCCGCCTCTGCGGCCTCGTCCTGGCGGACGGGCGGACCCTCGCCTGCGGCGCGGTGGTGCTGACCACCGGCACC
TTCCTGCGCGGCCTGATCCATATCGGCGAGCGGCAGATCCCGGCGGGCCGCGTCGGCGAGGCGCCGGCGGTCGGGCTGGC
CCAGACCCTCGAACGCCTCGGCCTCCGCCTCGGGCGCCTGAAGACCGGCACGCCCCCGCGCCTCGACGGGCGGACCATCG
ACTGGTCCGGCCTGGAGATGCAGGAGGCCGACGCCGAGCCGGTGCCGTTCTCGACGCTGACCGAGCGGATCACCAACCCG
CAGATCCGCTGCGGCATCACCCGGACCACTCGGGCCGTCCACGACCTGATCCGCGCCAACCTGCACCGCTCGCCGATGTA
TTCCGGCGGCATCGCCAGCCGGGGCCCGCGCTACTGCCCGTCGATCGAGGACAAGGTGGTGCGCTTCGGCGACCGGGAGG
GCCACCAGATTTTCCTGGAACCTGAAGGGCTCGACGATCCCACCATCTACCCGAACGGCATCTCGACGGCGCTGCCGGAG
GCGGTGCAACGCGACCTCGTGCGGCTGATCCCGGGCCTGGAGCGGGTCGAGATCCTGCGGCCGGGCTACGCCATCGAGTA
CGACTACGTCGATCCCCGGGAGCTCGATCTCGGCCTCCAGGTGAAGCGCCTGCCGGGCCTGTTCCTGGCCGGCCAGATCA
ACGGGACCACGGGCTACGAGGAGGCCGCCGGCCAGGGCCTGGTGGCCGGCCTCAACGCCGCCCGGCACGCGGGCGGCCTC
GGCATCGCGGGCTTCGACCGGGCCGAGTCGTATCTCGGCGTGATGATCGACGACCTCGTGACCCAGGGGGTCAGCGAGCC
GTACCGGATGTTCACCTCGCGCTCGGAGTACCGGCTGTCCCTGCGGGTCGACAACGCCGACGCCCGGCTGACGCCGCGCG
GGATCGCGCTCGGCTGCGTCGGGGGACACCGGGCGGCCCAGTTCGCGGCCGGGCAGGCGGCGCTCGGCGCGGCCCGCGCC
CGCCTCGACGCGGTGAGCCTGACGCCCAGCCAGGCCGCGCCCCACGGGATCAGCCTCAACCGCGACGGCATCCGCCGCAC
CGGCTTCCAGCTGCTCGCGTACCCGGAGATCGGATGGGCGGACTTGGCGGCGGTGTGGCCGGACCTGGCGGAGGTCCCCC
CGCGGATCGCCGACCGGATGAAGACCGACGCGACCTACGCGGTCTACCTCGACCGCCAGAACGCCGACATCGCGGCCTTC
CGCCGGGACGAGGCGGTGCGCCTGCCGCCGGGGCTCGACTACGCGGCGATCAGCGGCCTCTCGAACGAGATGCGGGTGAA
GCTCGAGACCGTGCGCCCCGGGACCCTGGGGCAGGCGGCCCGGATCGAGGGCGTCACCCCGGCGGCCCTCACCCTCCTGG
CCGCCCACGCAAGGCGCGGCGCGCGCGCGCCGTCGGCCCCCGCGGACCGGCACCCGGCATGA

Upstream 100 bases:

>100_bases
TCCCGGCAGATCCGCCGGTCCCCGCGCGCGCGGGCCGTGCACGGCGCGCGCGCCGCCCGCACCCGCGGCGGAATATCTGC
GAAAGGCTGCTCGGTACCCG

Downstream 100 bases:

>100_bases
GCGACCCGGATCGCGCCCGTGTCCTGGCGGCGGCCGGTGTTTCACGTGAAACAGCGGAGCGGCTCGACCTCTACGTGGCG
CAGCTGCGACGCTGGCAGCC

Product: tRNA uridine 5-carboxymethylaminomethyl modification protein GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MLTTSSARFDVAVVGGGHAGVEAAAAAARCGARTALVTHDPATIGAMSCNPAIGGLGKGHLVREVDALDGLMGRVADAAG
IQFRLLNRRKGPAVRGPRTQADRKLYAAAMQTAVAETAGLTVVAGACEDLAFDAEGRLCGLVLADGRTLACGAVVLTTGT
FLRGLIHIGERQIPAGRVGEAPAVGLAQTLERLGLRLGRLKTGTPPRLDGRTIDWSGLEMQEADAEPVPFSTLTERITNP
QIRCGITRTTRAVHDLIRANLHRSPMYSGGIASRGPRYCPSIEDKVVRFGDREGHQIFLEPEGLDDPTIYPNGISTALPE
AVQRDLVRLIPGLERVEILRPGYAIEYDYVDPRELDLGLQVKRLPGLFLAGQINGTTGYEEAAGQGLVAGLNAARHAGGL
GIAGFDRAESYLGVMIDDLVTQGVSEPYRMFTSRSEYRLSLRVDNADARLTPRGIALGCVGGHRAAQFAAGQAALGAARA
RLDAVSLTPSQAAPHGISLNRDGIRRTGFQLLAYPEIGWADLAAVWPDLAEVPPRIADRMKTDATYAVYLDRQNADIAAF
RRDEAVRLPPGLDYAAISGLSNEMRVKLETVRPGTLGQAARIEGVTPAALTLLAAHARRGARAPSAPADRHPA

Sequences:

>Translated_633_residues
MLTTSSARFDVAVVGGGHAGVEAAAAAARCGARTALVTHDPATIGAMSCNPAIGGLGKGHLVREVDALDGLMGRVADAAG
IQFRLLNRRKGPAVRGPRTQADRKLYAAAMQTAVAETAGLTVVAGACEDLAFDAEGRLCGLVLADGRTLACGAVVLTTGT
FLRGLIHIGERQIPAGRVGEAPAVGLAQTLERLGLRLGRLKTGTPPRLDGRTIDWSGLEMQEADAEPVPFSTLTERITNP
QIRCGITRTTRAVHDLIRANLHRSPMYSGGIASRGPRYCPSIEDKVVRFGDREGHQIFLEPEGLDDPTIYPNGISTALPE
AVQRDLVRLIPGLERVEILRPGYAIEYDYVDPRELDLGLQVKRLPGLFLAGQINGTTGYEEAAGQGLVAGLNAARHAGGL
GIAGFDRAESYLGVMIDDLVTQGVSEPYRMFTSRSEYRLSLRVDNADARLTPRGIALGCVGGHRAAQFAAGQAALGAARA
RLDAVSLTPSQAAPHGISLNRDGIRRTGFQLLAYPEIGWADLAAVWPDLAEVPPRIADRMKTDATYAVYLDRQNADIAAF
RRDEAVRLPPGLDYAAISGLSNEMRVKLETVRPGTLGQAARIEGVTPAALTLLAAHARRGARAPSAPADRHPA
>Mature_633_residues
MLTTSSARFDVAVVGGGHAGVEAAAAAARCGARTALVTHDPATIGAMSCNPAIGGLGKGHLVREVDALDGLMGRVADAAG
IQFRLLNRRKGPAVRGPRTQADRKLYAAAMQTAVAETAGLTVVAGACEDLAFDAEGRLCGLVLADGRTLACGAVVLTTGT
FLRGLIHIGERQIPAGRVGEAPAVGLAQTLERLGLRLGRLKTGTPPRLDGRTIDWSGLEMQEADAEPVPFSTLTERITNP
QIRCGITRTTRAVHDLIRANLHRSPMYSGGIASRGPRYCPSIEDKVVRFGDREGHQIFLEPEGLDDPTIYPNGISTALPE
AVQRDLVRLIPGLERVEILRPGYAIEYDYVDPRELDLGLQVKRLPGLFLAGQINGTTGYEEAAGQGLVAGLNAARHAGGL
GIAGFDRAESYLGVMIDDLVTQGVSEPYRMFTSRSEYRLSLRVDNADARLTPRGIALGCVGGHRAAQFAAGQAALGAARA
RLDAVSLTPSQAAPHGISLNRDGIRRTGFQLLAYPEIGWADLAAVWPDLAEVPPRIADRMKTDATYAVYLDRQNADIAAF
RRDEAVRLPPGLDYAAISGLSNEMRVKLETVRPGTLGQAARIEGVTPAALTLLAAHARRGARAPSAPADRHPA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=641, Percent_Identity=46.9578783151326, Blast_Score=534, Evalue=1e-151,
Organism=Homo sapiens, GI19882217, Length=666, Percent_Identity=45.1951951951952, Blast_Score=520, Evalue=1e-147,
Organism=Homo sapiens, GI183227703, Length=681, Percent_Identity=44.640234948605, Blast_Score=514, Evalue=1e-146,
Organism=Escherichia coli, GI2367273, Length=620, Percent_Identity=51.6129032258064, Blast_Score=577, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17534255, Length=619, Percent_Identity=42.3263327948304, Blast_Score=479, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6321202, Length=640, Percent_Identity=45.9375, Blast_Score=553, Evalue=1e-158,
Organism=Drosophila melanogaster, GI24658174, Length=633, Percent_Identity=46.6034755134281, Blast_Score=533, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_METRJ (B1M186)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001756744.1
- ProteinModelPortal:   B1M186
- SMR:   B1M186
- GeneID:   6140149
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_4091
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 67001; Mature: 67001

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTSSARFDVAVVGGGHAGVEAAAAAARCGARTALVTHDPATIGAMSCNPAIGGLGKGH
CCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCC
LVREVDALDGLMGRVADAAGIQFRLLNRRKGPAVRGPRTQADRKLYAAAMQTAVAETAGL
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TVVAGACEDLAFDAEGRLCGLVLADGRTLACGAVVLTTGTFLRGLIHIGERQIPAGRVGE
EEEECCHHHCEECCCCCEEEEEEECCCEEECCCCEEHHHHHHHHHHHHCCCCCCCCCCCC
APAVGLAQTLERLGLRLGRLKTGTPPRLDGRTIDWSGLEMQEADAEPVPFSTLTERITNP
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCHHCCCCCCCCHHHHHHHHCCC
QIRCGITRTTRAVHDLIRANLHRSPMYSGGIASRGPRYCPSIEDKVVRFGDREGHQIFLE
CEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEC
PEGLDDPTIYPNGISTALPEAVQRDLVRLIPGLERVEILRPGYAIEYDYVDPRELDLGLQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHEECCCCEEEECCCCCCCCCCCEE
VKRLPGLFLAGQINGTTGYEEAAGQGLVAGLNAARHAGGLGIAGFDRAESYLGVMIDDLV
EECCCCEEEEEEECCCCCCHHHCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
TQGVSEPYRMFTSRSEYRLSLRVDNADARLTPRGIALGCVGGHRAAQFAAGQAALGAARA
HHCCCHHHHHHCCCCCEEEEEEEECCCCEECCCCEEEEECCCCHHHHHHCCHHHHHHHHH
RLDAVSLTPSQAAPHGISLNRDGIRRTGFQLLAYPEIGWADLAAVWPDLAEVPPRIADRM
HHEEEECCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCHHHHHHHCCCHHHCCHHHHHHH
KTDATYAVYLDRQNADIAAFRRDEAVRLPPGLDYAAISGLSNEMRVKLETVRPGTLGQAA
CCCCEEEEEEECCCCCEEEEECCCCEECCCCCCHHHHHCCCCCEEEEEEEECCCCCCCHH
RIEGVTPAALTLLAAHARRGARAPSAPADRHPA
EECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTTSSARFDVAVVGGGHAGVEAAAAAARCGARTALVTHDPATIGAMSCNPAIGGLGKGH
CCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCC
LVREVDALDGLMGRVADAAGIQFRLLNRRKGPAVRGPRTQADRKLYAAAMQTAVAETAGL
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TVVAGACEDLAFDAEGRLCGLVLADGRTLACGAVVLTTGTFLRGLIHIGERQIPAGRVGE
EEEECCHHHCEECCCCCEEEEEEECCCEEECCCCEEHHHHHHHHHHHHCCCCCCCCCCCC
APAVGLAQTLERLGLRLGRLKTGTPPRLDGRTIDWSGLEMQEADAEPVPFSTLTERITNP
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCHHCCCCCCCCHHHHHHHHCCC
QIRCGITRTTRAVHDLIRANLHRSPMYSGGIASRGPRYCPSIEDKVVRFGDREGHQIFLE
CEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEC
PEGLDDPTIYPNGISTALPEAVQRDLVRLIPGLERVEILRPGYAIEYDYVDPRELDLGLQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHEECCCCEEEECCCCCCCCCCCEE
VKRLPGLFLAGQINGTTGYEEAAGQGLVAGLNAARHAGGLGIAGFDRAESYLGVMIDDLV
EECCCCEEEEEEECCCCCCHHHCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
TQGVSEPYRMFTSRSEYRLSLRVDNADARLTPRGIALGCVGGHRAAQFAAGQAALGAARA
HHCCCHHHHHHCCCCCEEEEEEEECCCCEECCCCEEEEECCCCHHHHHHCCHHHHHHHHH
RLDAVSLTPSQAAPHGISLNRDGIRRTGFQLLAYPEIGWADLAAVWPDLAEVPPRIADRM
HHEEEECCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCHHHHHHHCCCHHHCCHHHHHHH
KTDATYAVYLDRQNADIAAFRRDEAVRLPPGLDYAAISGLSNEMRVKLETVRPGTLGQAA
CCCCEEEEEEECCCCCEEEEECCCCEECCCCCCHHHHHCCCCCEEEEEEEECCCCCCCHH
RIEGVTPAALTLLAAHARRGARAPSAPADRHPA
EECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA