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The map label for this gene is panC [H]

Identifier: 170750478

GI number: 170750478

Start: 4336990

End: 4337838

Strand: Direct

Name: panC [H]

Synonym: Mrad2831_4085

Alternate gene names: 170750478

Gene position: 4336990-4337838 (Clockwise)

Preceding gene: 170750477

Following gene: 170750479

Centisome position: 71.36

GC content: 75.38

Gene sequence:

>849_bases
GTGTCCGAGTCGACCTTCCAGTCCTTCCGCGACCTCACCGCCCTGCGCGGATGCGTGGCGGCGTGGCGCGCGGCGGGCGA
GCGCGTCGTCCTGATCCCCACCATGGGGGCCCTGCACGACGGGCACCTCGCCCTCGTGGCCGAGGCGCGGCGGATCGGCC
GCCGGACCGTCGCCAGCATCTTCGTCAATCCGACCCAGTTCGGCCCGAACGAGGATTTCGCCCGCTACCCCCGCGACCTC
GACGCGGACCTGGCCCTGCTGGCGCGAGCCGGCGCGGACGCCGCCTGGACGCCCAGCGTCGAGACCATGTACCCGCCCGG
CTTCGCCACCCGGATCGAGGTCGCCGGCCTGACCGACGGCCTGTGCGGGCCGTTCCGGCCCGGCCACTTCGCCGGCGTCG
CCACGGTGGTGACCAAGCTCCTCAACCAGGTCCGGCCGGACGTCGCCCTGTTCGGCGAGAAGGACTTCCAGCAGCTCCGC
GTGCTCCAGCAGGTGGCGGCGGATCTCGACCTCCCGGTGGAGATCCGCGGCGTGCCGACCGTGCGCGAGCCCGACGGCCT
CGCGCTGTCGTCGCGCAACCGCTACCTCTCGGCCGAGGAGCGGGCCGTCGCCCCGAAGCTCCACGCCGTCCTGGCCGAGA
TCGCCTCCGCGTCCCGCAGCGGCACCCCCGTGGCCGGCCGGATCGCCGCCGGGCGGGCGGCGCTGGAGGCGGCGGGGTTC
CGCGTCCAGTACCTCGCGGTCTGCGACGCCCGGACCCTGGTCCCGGTGGAGCGGGTCGACGGCCCGGCCCGCGTGATCGC
CGCGGCCTTCCTGGGCCGGACCCGGCTGATCGACAATCGCGCCGTCTAG

Upstream 100 bases:

>100_bases
TGACGCCGACCGGGACCGCGCGGACCGTGACCGGACTGCCGGATTCCACCGCTCCCCATCATGCTCTAGACCGGCCCCAC
CCTCCCCCGGAGCCCGTGCC

Downstream 100 bases:

>100_bases
GCCGGCGCCGGTCCGGCCGCCGGCGGTCGTGGCCGCCGGGCCACGATGCGCGGATTTCCGGCTTTGACTGCGCCAAGTGA
TTGGCGCCGCCCGGCCGACC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSESTFQSFRDLTALRGCVAAWRAAGERVVLIPTMGALHDGHLALVAEARRIGRRTVASIFVNPTQFGPNEDFARYPRDL
DADLALLARAGADAAWTPSVETMYPPGFATRIEVAGLTDGLCGPFRPGHFAGVATVVTKLLNQVRPDVALFGEKDFQQLR
VLQQVAADLDLPVEIRGVPTVREPDGLALSSRNRYLSAEERAVAPKLHAVLAEIASASRSGTPVAGRIAAGRAALEAAGF
RVQYLAVCDARTLVPVERVDGPARVIAAAFLGRTRLIDNRAV

Sequences:

>Translated_282_residues
MSESTFQSFRDLTALRGCVAAWRAAGERVVLIPTMGALHDGHLALVAEARRIGRRTVASIFVNPTQFGPNEDFARYPRDL
DADLALLARAGADAAWTPSVETMYPPGFATRIEVAGLTDGLCGPFRPGHFAGVATVVTKLLNQVRPDVALFGEKDFQQLR
VLQQVAADLDLPVEIRGVPTVREPDGLALSSRNRYLSAEERAVAPKLHAVLAEIASASRSGTPVAGRIAAGRAALEAAGF
RVQYLAVCDARTLVPVERVDGPARVIAAAFLGRTRLIDNRAV
>Mature_281_residues
SESTFQSFRDLTALRGCVAAWRAAGERVVLIPTMGALHDGHLALVAEARRIGRRTVASIFVNPTQFGPNEDFARYPRDLD
ADLALLARAGADAAWTPSVETMYPPGFATRIEVAGLTDGLCGPFRPGHFAGVATVVTKLLNQVRPDVALFGEKDFQQLRV
LQQVAADLDLPVEIRGVPTVREPDGLALSSRNRYLSAEERAVAPKLHAVLAEIASASRSGTPVAGRIAAGRAALEAAGFR
VQYLAVCDARTLVPVERVDGPARVIAAAFLGRTRLIDNRAV

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=275, Percent_Identity=47.6363636363636, Blast_Score=238, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6322046, Length=301, Percent_Identity=35.5481727574751, Blast_Score=176, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 30173; Mature: 30042

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESTFQSFRDLTALRGCVAAWRAAGERVVLIPTMGALHDGHLALVAEARRIGRRTVASI
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
FVNPTQFGPNEDFARYPRDLDADLALLARAGADAAWTPSVETMYPPGFATRIEVAGLTDG
EECCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
LCGPFRPGHFAGVATVVTKLLNQVRPDVALFGEKDFQQLRVLQQVAADLDLPVEIRGVPT
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCC
VREPDGLALSSRNRYLSAEERAVAPKLHAVLAEIASASRSGTPVAGRIAAGRAALEAAGF
CCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
RVQYLAVCDARTLVPVERVDGPARVIAAAFLGRTRLIDNRAV
EEEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SESTFQSFRDLTALRGCVAAWRAAGERVVLIPTMGALHDGHLALVAEARRIGRRTVASI
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
FVNPTQFGPNEDFARYPRDLDADLALLARAGADAAWTPSVETMYPPGFATRIEVAGLTDG
EECCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
LCGPFRPGHFAGVATVVTKLLNQVRPDVALFGEKDFQQLRVLQQVAADLDLPVEIRGVPT
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCC
VREPDGLALSSRNRYLSAEERAVAPKLHAVLAEIASASRSGTPVAGRIAAGRAALEAAGF
CCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
RVQYLAVCDARTLVPVERVDGPARVIAAAFLGRTRLIDNRAV
EEEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA