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The map label for this gene is yheS [H]

Identifier: 170750472

GI number: 170750472

Start: 4331255

End: 4332877

Strand: Direct

Name: yheS [H]

Synonym: Mrad2831_4079

Alternate gene names: 170750472

Gene position: 4331255-4332877 (Clockwise)

Preceding gene: 170750470

Following gene: 170750473

Centisome position: 71.26

GC content: 69.62

Gene sequence:

>1623_bases
ATGATACGCCTGGACAAGATCACCAAGCAGAACGGGCGGCAGCTCGTCTTCATCGAGGCCTCGGCCGCCCTGCAGCGGGG
CGAGAAGGTCGGCCTGGTCGGCCCGAACGGGGCCGGCAAGACCACCCTGTTCCGGATGATCATCGGCCAGGAGCAGCCCG
ACGAGGGGCAGGTCGCCGCCGACCGGGGCATCACCATCGGCTATTTCAGCCAGGATGTCGGCGAGATGTCGGGGCGCAGC
GTCGTCACCGAGGTGATGGACGGCGCCGGCCCGGTGAGCGCGGTGGCGGCCGAGCTCGCCGAGCTCGGCGCGGCGCTCGC
CGACCCGGACCGCGCCGACGAGATGGACGCCCTGGTCGAGCGCTACGGCGAGGTCCAGGCGCGGTTCGAGGAGCTCGACG
GCTACGCCCTGGAGGGCCGGGCCCGCGAGGTGCTCGACGGGCTGAGCTTCAGCCAGGAGATGATGGACGGCGACGTCGGC
GCCCTCTCGGGCGGCTGGAAGATGCGCGTCGCCCTCGCCCGCATCCTGCTGATGCGCCCGGACGTGATGCTCCTCGACGA
GCCGTCGAACCACCTCGACATCGAGAGCCTGATCTGGCTCGAATCGTTCCTGAAGGGCTACGACGGCGCCCTGCTGATGA
CCTCGCACGACCGCGAGTTCATGAACCGCATCGTCACCAAGATCATCGAGATCGACGCCGGCGCGCTCACCACCTACTCG
GGCGACTACGCCTTCTACGAGGGCCAGCGGAAGCTCAACGAGGCGCAGGCCCAGGCGCAGTACGAGCGCCAGCAGGCCAT
GCTGGCGAAGGAGATCGCCTTCATCGAGCGGTTCAAGGCCCGGGCCTCCCACGCCGCCCAGGTGCAGAGCCGGGTGAAGA
AGCTCGACAAGATCGAGCGGGTCGAGCCGCCCCGGCGGCGGCAATCGGTGGCGTTCGAGTTCCAGCCGGCGCCGCGCTCG
GGCGACGACGTCGTGATGCTCAAGGGCGTGAACAAGCGCTACGGCAGCCGCACGATCTACGAGGGGCTCGACTTCTCGGT
GCGGCGCAAGGAGCGCTGGTGCGTGATGGGCATCAACGGCGCCGGCAAGTCGACGCTGCTGAAGCTCGTCACCGGCACCA
CCGCGCCCGACGACGGCTCGGTCACGGTCGGCGGCAGCGTGAAGCTCGGCTACTTCGCCCAGCACGCCATGGACCTGCTC
GAGGGCGACCGCACCGTGTTCCAGACCCTGGAGGATGCCTTCCCGCAGGCCGGCCAGGGGTCCCTGCGGGCGCTGGCCGG
CTGCTTCGGCTTCTCGGGCGACGACGTCGAGAAGCGCTGCCGGGTGCTCTCGGGCGGCGAGAAGGCCCGGCTGGTCATGG
CGCTGATGCTCTACGACCCGCCGAACTTCCTGGTGCTCGACGAGCCGACCAACCACCTCGACATGGGCACCAAGGAGATG
CTGATCGAGGCGCTGGCCAACTACGAGGGGACGATGCTGTTCGTGTCCCACGACCGGCACTTCCTGGCCGCGCTGTCGAA
CCGGGTGCTGGAGGTGACCCCGGAGGGCATCCACCAGTACGGCGGCGGCTACACCGAGTACGTGGCCCGCACCGGCCAGG
AGGCGCCCGGCCTGCGCAGCTGA

Upstream 100 bases:

>100_bases
CGCCGGACGCAAGCGTTATCCCGCACTGCGGCACCCCGCCTTTGCGCCGCGTCGGCCGATGCCGTAAGCGGCCGGGATAC
TCCCGGACAGCGCCCGCCCC

Downstream 100 bases:

>100_bases
GGGGCCACGCCGTCGTCGCGAGCGCAGCGAGGCGCCCCAGGGCAGCGCGACCTCGATCAGCGTGGCGCGGCTGGACGGCG
TCGCTCCGCTCGCGGGGACG

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MIRLDKITKQNGRQLVFIEASAALQRGEKVGLVGPNGAGKTTLFRMIIGQEQPDEGQVAADRGITIGYFSQDVGEMSGRS
VVTEVMDGAGPVSAVAAELAELGAALADPDRADEMDALVERYGEVQARFEELDGYALEGRAREVLDGLSFSQEMMDGDVG
ALSGGWKMRVALARILLMRPDVMLLDEPSNHLDIESLIWLESFLKGYDGALLMTSHDREFMNRIVTKIIEIDAGALTTYS
GDYAFYEGQRKLNEAQAQAQYERQQAMLAKEIAFIERFKARASHAAQVQSRVKKLDKIERVEPPRRRQSVAFEFQPAPRS
GDDVVMLKGVNKRYGSRTIYEGLDFSVRRKERWCVMGINGAGKSTLLKLVTGTTAPDDGSVTVGGSVKLGYFAQHAMDLL
EGDRTVFQTLEDAFPQAGQGSLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMALMLYDPPNFLVLDEPTNHLDMGTKEM
LIEALANYEGTMLFVSHDRHFLAALSNRVLEVTPEGIHQYGGGYTEYVARTGQEAPGLRS

Sequences:

>Translated_540_residues
MIRLDKITKQNGRQLVFIEASAALQRGEKVGLVGPNGAGKTTLFRMIIGQEQPDEGQVAADRGITIGYFSQDVGEMSGRS
VVTEVMDGAGPVSAVAAELAELGAALADPDRADEMDALVERYGEVQARFEELDGYALEGRAREVLDGLSFSQEMMDGDVG
ALSGGWKMRVALARILLMRPDVMLLDEPSNHLDIESLIWLESFLKGYDGALLMTSHDREFMNRIVTKIIEIDAGALTTYS
GDYAFYEGQRKLNEAQAQAQYERQQAMLAKEIAFIERFKARASHAAQVQSRVKKLDKIERVEPPRRRQSVAFEFQPAPRS
GDDVVMLKGVNKRYGSRTIYEGLDFSVRRKERWCVMGINGAGKSTLLKLVTGTTAPDDGSVTVGGSVKLGYFAQHAMDLL
EGDRTVFQTLEDAFPQAGQGSLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMALMLYDPPNFLVLDEPTNHLDMGTKEM
LIEALANYEGTMLFVSHDRHFLAALSNRVLEVTPEGIHQYGGGYTEYVARTGQEAPGLRS
>Mature_540_residues
MIRLDKITKQNGRQLVFIEASAALQRGEKVGLVGPNGAGKTTLFRMIIGQEQPDEGQVAADRGITIGYFSQDVGEMSGRS
VVTEVMDGAGPVSAVAAELAELGAALADPDRADEMDALVERYGEVQARFEELDGYALEGRAREVLDGLSFSQEMMDGDVG
ALSGGWKMRVALARILLMRPDVMLLDEPSNHLDIESLIWLESFLKGYDGALLMTSHDREFMNRIVTKIIEIDAGALTTYS
GDYAFYEGQRKLNEAQAQAQYERQQAMLAKEIAFIERFKARASHAAQVQSRVKKLDKIERVEPPRRRQSVAFEFQPAPRS
GDDVVMLKGVNKRYGSRTIYEGLDFSVRRKERWCVMGINGAGKSTLLKLVTGTTAPDDGSVTVGGSVKLGYFAQHAMDLL
EGDRTVFQTLEDAFPQAGQGSLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMALMLYDPPNFLVLDEPTNHLDMGTKEM
LIEALANYEGTMLFVSHDRHFLAALSNRVLEVTPEGIHQYGGGYTEYVARTGQEAPGLRS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=530, Percent_Identity=33.5849056603774, Blast_Score=290, Evalue=3e-78,
Organism=Homo sapiens, GI27881506, Length=539, Percent_Identity=32.6530612244898, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI10947137, Length=539, Percent_Identity=32.6530612244898, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI10947135, Length=538, Percent_Identity=31.9702602230483, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI69354671, Length=538, Percent_Identity=31.9702602230483, Blast_Score=221, Evalue=1e-57,
Organism=Escherichia coli, GI1789751, Length=527, Percent_Identity=37.3814041745731, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1787041, Length=537, Percent_Identity=34.6368715083799, Blast_Score=330, Evalue=2e-91,
Organism=Escherichia coli, GI2367384, Length=507, Percent_Identity=33.9250493096647, Blast_Score=284, Evalue=8e-78,
Organism=Escherichia coli, GI1787182, Length=530, Percent_Identity=33.7735849056604, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87081782, Length=541, Percent_Identity=24.9537892791128, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788165, Length=203, Percent_Identity=29.064039408867, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787758, Length=212, Percent_Identity=25.9433962264151, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788897, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789873, Length=230, Percent_Identity=26.9565217391304, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787164, Length=197, Percent_Identity=30.9644670050761, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=533, Percent_Identity=33.9587242026266, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17555318, Length=523, Percent_Identity=33.2695984703633, Blast_Score=274, Evalue=9e-74,
Organism=Caenorhabditis elegans, GI17559834, Length=535, Percent_Identity=30.2803738317757, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI71983516, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71983510, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI115534520, Length=210, Percent_Identity=27.6190476190476, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=204, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=538, Percent_Identity=31.7843866171004, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6321121, Length=548, Percent_Identity=29.5620437956204, Blast_Score=263, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6325030, Length=266, Percent_Identity=31.203007518797, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=414, Percent_Identity=26.8115942028986, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6323278, Length=442, Percent_Identity=26.4705882352941, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24666836, Length=530, Percent_Identity=33.2075471698113, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24642252, Length=515, Percent_Identity=32.621359223301, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI18859989, Length=515, Percent_Identity=32.621359223301, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI24641342, Length=538, Percent_Identity=28.6245353159851, Blast_Score=241, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59347; Mature: 59347

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLDKITKQNGRQLVFIEASAALQRGEKVGLVGPNGAGKTTLFRMIIGQEQPDEGQVAA
CCCCCCCCCCCCCEEEEEECHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEC
DRGITIGYFSQDVGEMSGRSVVTEVMDGAGPVSAVAAELAELGAALADPDRADEMDALVE
CCCCEEEECCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RYGEVQARFEELDGYALEGRAREVLDGLSFSQEMMDGDVGALSGGWKMRVALARILLMRP
HHHHHHHHHHHCCCEEECCHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
DVMLLDEPSNHLDIESLIWLESFLKGYDGALLMTSHDREFMNRIVTKIIEIDAGALTTYS
CEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEC
GDYAFYEGQRKLNEAQAQAQYERQQAMLAKEIAFIERFKARASHAAQVQSRVKKLDKIER
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEPPRRRQSVAFEFQPAPRSGDDVVMLKGVNKRYGSRTIYEGLDFSVRRKERWCVMGING
CCCCHHHCCEEEEECCCCCCCCCEEEEECCCCCCCCCHHHCCCCCEEECCCCEEEEEECC
AGKSTLLKLVTGTTAPDDGSVTVGGSVKLGYFAQHAMDLLEGDRTVFQTLEDAFPQAGQG
CCHHHHHHHHCCCCCCCCCCEEECCCEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
SLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMALMLYDPPNFLVLDEPTNHLDMGTKEM
HHHHHHHHHCCCCCCHHHHHHHHCCCCHHHEEEEEEEECCCCEEEECCCCCCCCCCHHHH
LIEALANYEGTMLFVSHDRHFLAALSNRVLEVTPEGIHQYGGGYTEYVARTGQEAPGLRS
HHHHHHCCCCEEEEEECCCHHHHHHHCCEEEECCHHHHHHCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIRLDKITKQNGRQLVFIEASAALQRGEKVGLVGPNGAGKTTLFRMIIGQEQPDEGQVAA
CCCCCCCCCCCCCEEEEEECHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEC
DRGITIGYFSQDVGEMSGRSVVTEVMDGAGPVSAVAAELAELGAALADPDRADEMDALVE
CCCCEEEECCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RYGEVQARFEELDGYALEGRAREVLDGLSFSQEMMDGDVGALSGGWKMRVALARILLMRP
HHHHHHHHHHHCCCEEECCHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
DVMLLDEPSNHLDIESLIWLESFLKGYDGALLMTSHDREFMNRIVTKIIEIDAGALTTYS
CEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEC
GDYAFYEGQRKLNEAQAQAQYERQQAMLAKEIAFIERFKARASHAAQVQSRVKKLDKIER
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEPPRRRQSVAFEFQPAPRSGDDVVMLKGVNKRYGSRTIYEGLDFSVRRKERWCVMGING
CCCCHHHCCEEEEECCCCCCCCCEEEEECCCCCCCCCHHHCCCCCEEECCCCEEEEEECC
AGKSTLLKLVTGTTAPDDGSVTVGGSVKLGYFAQHAMDLLEGDRTVFQTLEDAFPQAGQG
CCHHHHHHHHCCCCCCCCCCEEECCCEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
SLRALAGCFGFSGDDVEKRCRVLSGGEKARLVMALMLYDPPNFLVLDEPTNHLDMGTKEM
HHHHHHHHHCCCCCCHHHHHHHHCCCCHHHEEEEEEEECCCCEEEECCCCCCCCCCHHHH
LIEALANYEGTMLFVSHDRHFLAALSNRVLEVTPEGIHQYGGGYTEYVARTGQEAPGLRS
HHHHHHCCCCEEEEEECCCHHHHHHHCCEEEECCHHHHHHCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]