Click here to switch to the map view.

The map label for this gene is mcpA [H]

Identifier: 170750454

GI number: 170750454

Start: 4305641

End: 4307332

Strand: Reverse

Name: mcpA [H]

Synonym: Mrad2831_4059

Alternate gene names: 170750454

Gene position: 4307332-4305641 (Counterclockwise)

Preceding gene: 170750455

Following gene: 170750452

Centisome position: 70.87

GC content: 73.88

Gene sequence:

>1692_bases
ATGCGCCTTCACCTGACAGTCAAAGCGTCGCTCCTCGCCGCCTTCGGCCTCCTCGCGCTCCTGTGCGCCGGCCAGGCCGT
TCTCACGACCCTCACGCTCTCCGGGATCCGGGCCAACGTCACGGGCGTCGCCACGAACTGGCTCCCCTCCGTCGTGGCGA
TCACCAACATCCGCGCCGCGGCCTCGGATGTGCGCATCAAGCAGTTGCGCACGCTGACCCTGTCCGGCAGTCCCGAGACG
CGGGCCGACAACGCGCGGCAGACCGACCAGGCCGTCGCGGCGCTCGCCGCCGCCCGGAAGGCCTACGAGCCGCTGATCTC
GTCGGACGCGGAGCGGGCCCTCTACGACGCCTTCGGCGCCACCTGGGAGCGCTACCAGACCGTCGGCCGCGAGGCGGCGC
GCCTGGCGGAGGCGGGCCAGGGTGCCGACGGCATCCGGCTCATGGCCGACCCGGCCAACATCGATCTCTACAACGAGGCC
CGCGACACGCTGGCCAAGGACGTCGCCCTGAACGAGCGCGGCGCGCACGCGGACGCCGAGAGCGCCATGGCGGCGACGGA
TTTCGCGACCCTGACGGCCTATCTCTCCGCCGCGCTGAGCGTGCTGGCGGCCTGCGGCGCCACCGCGTTCGTGCTGCTGC
GCGTGTCCCGCCCGATCCAGGCGATGACGGGCGCGATGACCGTCCTGGCCGCGGGCGACACGGGGGGCGAGGTGCCCCAC
CGCGCGCGCCGCGACGAGGTCGGCGCGATGGCGGCGGCCGTTCAGGTGTTCAAGGACAACCTGATCCGCACCCGCCGTCT
GGAGGACGAGACCGCGCAGGCGCGCCTGGCCGCCGAGGAGCAGCGCAAGGCCGGCATGCGGCAGATGGCCGACGACTTCG
AGGCCGCGGTCGGCGGGATCATCGGCACGGTGTCGTCCTCCGCGACCGAGCTGCAGGCGACCGCGCAGGCGATGACCGCC
ACCGCCACCGAGACCGCCAGCCAGTCGACGACCGTGGCGGCGGCGGCCGAGGAAGCCGCCTCCAACGTCAGCACGGTCGC
GGCGGCGGCCGAGGAGCTCGGCTCGTCGGTGCAGGAGATCGGCCGGCAGGTGCAGGGCTCGGCCAGCCTCGCGCACCTCG
CGGTGAGCGAGGCCGATCAGACCGGTCTCCGCGTGCAGGAACTCAGCGCCGCCGTCACCCGCATCGGCGACGTGGTCGGG
CTGATCTCGAACATCGCCGGCCAGACCAACCTGCTGGCGCTCAACGCCACCATCGAGGCGGCCCGGGCCGGGGCCGCCGG
CAAGGGCTTCGCGGTGGTGGCCTCCGAGGTCAAGGCGCTGGCCGAGCAGACCGCCAGGGCGACGCACGAGATCTCCGGCC
AGATCGCGCAGATCCAGGCCTCGACCGGGCAGGCGGTCACGTCGATCGCCGGCATCACCGGCCGGATCCGCGAGATCAGC
GGCGTGGCGACCTCGATCGCCGCCGCGGTCGAGCAGCAGGGTGCGGCGACCCAGGAGATCGTCCGCAACGTGGCGCAGGC
CTCGACCGGCACCAGCGAGGTGACGGGCAACATGGCCGGGGTGGCGCAGGCGTCGGAGGAGACGGGGGCCGCGGCCGGCC
AGGTCCTCGACGCGGCCTCGGAGCTGTCGCGGCAATCCGAGCATCTCGGCGCCGAGGTCGGCCGCTTCCTCGCGACCGTC
CGCGCCGCCTGA

Upstream 100 bases:

>100_bases
GGTCCAGGCTCACCCCTTCGTGCCCGTGCGGCCGCCCGACCGTCTGCGCTCCGGCAGGCGCCGTCGCGGACGTGCGGAAT
GCCTCGTCCAGGACCGGATC

Downstream 100 bases:

>100_bases
GCGCGTCAGGGCCGGGTGCGCGACGGCGCATCCGGACCCGCCGACGGGGCGGCCGGGGCCGCGAGCTTCAGCGCGTGGTC
CCGGATGTCGGGGGGCCACG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MRLHLTVKASLLAAFGLLALLCAGQAVLTTLTLSGIRANVTGVATNWLPSVVAITNIRAAASDVRIKQLRTLTLSGSPET
RADNARQTDQAVAALAAARKAYEPLISSDAERALYDAFGATWERYQTVGREAARLAEAGQGADGIRLMADPANIDLYNEA
RDTLAKDVALNERGAHADAESAMAATDFATLTAYLSAALSVLAACGATAFVLLRVSRPIQAMTGAMTVLAAGDTGGEVPH
RARRDEVGAMAAAVQVFKDNLIRTRRLEDETAQARLAAEEQRKAGMRQMADDFEAAVGGIIGTVSSSATELQATAQAMTA
TATETASQSTTVAAAAEEAASNVSTVAAAAEELGSSVQEIGRQVQGSASLAHLAVSEADQTGLRVQELSAAVTRIGDVVG
LISNIAGQTNLLALNATIEAARAGAAGKGFAVVASEVKALAEQTARATHEISGQIAQIQASTGQAVTSIAGITGRIREIS
GVATSIAAAVEQQGAATQEIVRNVAQASTGTSEVTGNMAGVAQASEETGAAAGQVLDAASELSRQSEHLGAEVGRFLATV
RAA

Sequences:

>Translated_563_residues
MRLHLTVKASLLAAFGLLALLCAGQAVLTTLTLSGIRANVTGVATNWLPSVVAITNIRAAASDVRIKQLRTLTLSGSPET
RADNARQTDQAVAALAAARKAYEPLISSDAERALYDAFGATWERYQTVGREAARLAEAGQGADGIRLMADPANIDLYNEA
RDTLAKDVALNERGAHADAESAMAATDFATLTAYLSAALSVLAACGATAFVLLRVSRPIQAMTGAMTVLAAGDTGGEVPH
RARRDEVGAMAAAVQVFKDNLIRTRRLEDETAQARLAAEEQRKAGMRQMADDFEAAVGGIIGTVSSSATELQATAQAMTA
TATETASQSTTVAAAAEEAASNVSTVAAAAEELGSSVQEIGRQVQGSASLAHLAVSEADQTGLRVQELSAAVTRIGDVVG
LISNIAGQTNLLALNATIEAARAGAAGKGFAVVASEVKALAEQTARATHEISGQIAQIQASTGQAVTSIAGITGRIREIS
GVATSIAAAVEQQGAATQEIVRNVAQASTGTSEVTGNMAGVAQASEETGAAAGQVLDAASELSRQSEHLGAEVGRFLATV
RAA
>Mature_563_residues
MRLHLTVKASLLAAFGLLALLCAGQAVLTTLTLSGIRANVTGVATNWLPSVVAITNIRAAASDVRIKQLRTLTLSGSPET
RADNARQTDQAVAALAAARKAYEPLISSDAERALYDAFGATWERYQTVGREAARLAEAGQGADGIRLMADPANIDLYNEA
RDTLAKDVALNERGAHADAESAMAATDFATLTAYLSAALSVLAACGATAFVLLRVSRPIQAMTGAMTVLAAGDTGGEVPH
RARRDEVGAMAAAVQVFKDNLIRTRRLEDETAQARLAAEEQRKAGMRQMADDFEAAVGGIIGTVSSSATELQATAQAMTA
TATETASQSTTVAAAAEEAASNVSTVAAAAEELGSSVQEIGRQVQGSASLAHLAVSEADQTGLRVQELSAAVTRIGDVVG
LISNIAGQTNLLALNATIEAARAGAAGKGFAVVASEVKALAEQTARATHEISGQIAQIQASTGQAVTSIAGITGRIREIS
GVATSIAAAVEQQGAATQEIVRNVAQASTGTSEVTGNMAGVAQASEETGAAAGQVLDAASELSRQSEHLGAEVGRFLATV
RAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=269, Percent_Identity=31.5985130111524, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI2367378, Length=267, Percent_Identity=31.0861423220974, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787690, Length=405, Percent_Identity=27.1604938271605, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788195, Length=261, Percent_Identity=30.6513409961686, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789453, Length=270, Percent_Identity=29.2592592592593, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57457; Mature: 57457

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLHLTVKASLLAAFGLLALLCAGQAVLTTLTLSGIRANVTGVATNWLPSVVAITNIRAA
CEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
ASDVRIKQLRTLTLSGSPETRADNARQTDQAVAALAAARKAYEPLISSDAERALYDAFGA
HHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
TWERYQTVGREAARLAEAGQGADGIRLMADPANIDLYNEARDTLAKDVALNERGAHADAE
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
SAMAATDFATLTAYLSAALSVLAACGATAFVLLRVSRPIQAMTGAMTVLAAGDTGGEVPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCCCCCC
RARRDEVGAMAAAVQVFKDNLIRTRRLEDETAQARLAAEEQRKAGMRQMADDFEAAVGGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGTVSSSATELQATAQAMTATATETASQSTTVAAAAEEAASNVSTVAAAAEELGSSVQEI
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRQVQGSASLAHLAVSEADQTGLRVQELSAAVTRIGDVVGLISNIAGQTNLLALNATIEA
HHHHCCCHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
ARAGAAGKGFAVVASEVKALAEQTARATHEISGQIAQIQASTGQAVTSIAGITGRIREIS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHH
GVATSIAAAVEQQGAATQEIVRNVAQASTGTSEVTGNMAGVAQASEETGAAAGQVLDAAS
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHHH
ELSRQSEHLGAEVGRFLATVRAA
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLHLTVKASLLAAFGLLALLCAGQAVLTTLTLSGIRANVTGVATNWLPSVVAITNIRAA
CEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
ASDVRIKQLRTLTLSGSPETRADNARQTDQAVAALAAARKAYEPLISSDAERALYDAFGA
HHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
TWERYQTVGREAARLAEAGQGADGIRLMADPANIDLYNEARDTLAKDVALNERGAHADAE
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
SAMAATDFATLTAYLSAALSVLAACGATAFVLLRVSRPIQAMTGAMTVLAAGDTGGEVPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEECCCCCCCCC
RARRDEVGAMAAAVQVFKDNLIRTRRLEDETAQARLAAEEQRKAGMRQMADDFEAAVGGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGTVSSSATELQATAQAMTATATETASQSTTVAAAAEEAASNVSTVAAAAEELGSSVQEI
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRQVQGSASLAHLAVSEADQTGLRVQELSAAVTRIGDVVGLISNIAGQTNLLALNATIEA
HHHHCCCHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
ARAGAAGKGFAVVASEVKALAEQTARATHEISGQIAQIQASTGQAVTSIAGITGRIREIS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHH
GVATSIAAAVEQQGAATQEIVRNVAQASTGTSEVTGNMAGVAQASEETGAAAGQVLDAAS
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHHH
ELSRQSEHLGAEVGRFLATVRAA
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]