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The map label for this gene is citN [H]

Identifier: 170750444

GI number: 170750444

Start: 4294435

End: 4295751

Strand: Reverse

Name: citN [H]

Synonym: Mrad2831_4049

Alternate gene names: 170750444

Gene position: 4295751-4294435 (Counterclockwise)

Preceding gene: 170750446

Following gene: 170750443

Centisome position: 70.68

GC content: 70.99

Gene sequence:

>1317_bases
ATGCTGGCCCTGCTCGGCCTGTGCACGATCGCGCTGCTGCTCGCCGTCATCCTGACCAAGCGGATGTCGCCCCTCGTGGC
GCTGATCGTCATCCCGGTCGCGGCCGCCCTGATCGGCGGGTTCGGCTTCGAGACCGGCAAGTTCGTCCTCGCGGGCCTGC
AGAGCCTCGCGGGCGTCGTCGGCATGTTCGTGTTCGCGATCCTGTTCTTCGGCATCGTCAGCGATGCCGGGATGCTCGAC
CCGATCATCGACCGGATCCTCGCCCGGGTCGGCACCCGCCCCACCCGGATCGTGCCCGGCACCACCCTGCTGGCGCTGCT
GATCCACCTCGACGGGTCGGGTGCGGTGACGTTCCTGATCACCATCCCGGCGATGCTGCCGCTCTACGACCGCGTCGGCA
TCGACCGGCGCATCCTGGCCTGCGCCGCCTCGATGGCGGCCGGCGTGAACTTCCTGCCCTGGACCGGGCCGATGATCCGC
GCCTCCGCCGCCCTGAAGCTGCCGATCCCCGAGATCTTCTCGCCCCTCGTGCCGGTTCAGGCGGTCGGCCTCGTCTTCAT
CTTCGCCGTCTCGTACTGGCTCGGCCTTCGGGAGGAGCGCCGTCTGGCCCACGTCCCCGGCGCCGCGGGGGCCGCCCCCG
GCCCGGCCGCGACCGCCCGGATCCTGAGCGACGCGGAGCGGACCCTGCGCCGCCCCGACCGCTTCTGGATCAACCTCGTC
CTCACGGCGGCGGTCCTGGGGACGATGGTCTTCCTGGCCGAGAAGGTGCCGCCGGCGCTGATGTTCATGCTCGGCACGGC
GCTCGCGCTGGTCATCAACTACCCGCAGGTCGACGCCCAGCGGCAGCGGATCGACGCGCACGCCAGGGCCGCGATCCTGA
TGGCCTCGATCCTCCTCGCCGCCGGCGTGTTCACCGGGATCATGCAGGGCACCGGCATGCTCAGGGCCATGGCCCAGACG
GCCGTCACCTTCGTGCCGCCGGAGATGGGGCGCCACATCCCGTTCGCGCTCGGCCTCGTGTCGATGCCCCTGTCGATGCT
GTTCGACCCGGACTCGTTCTACTTCGGCGTCCTGCCGGTGGTGGCGGAGGTGGCCCACCAACTCGGCGTCCCGCCGGTGC
AGGTCGCCCAGGGGGCGCTGCTCGGCCAGATGACGACGGGCTTCCCCGTCAGCCCGCTGACGCCCGCGACCTTCCTGGTC
TGCGGCCTGACCGGGATCGACCTCGCCGACCACCAGAAGTTCACCTTCCCGTTCCTGCTGGCGGCCTCGGTGGTGATGAC
CCTCACCTGCGTCGTCCTCGGGGTCTTCCCCCTCTGA

Upstream 100 bases:

>100_bases
GCGATCCGATCTTTTCAATTGTGTCATGAAGTGTTCCGCCGTCTCCTGACCCGATACAGGCGCGGATTCGAACCGCGCCG
GCGCCCAACGGGAGGAACGG

Downstream 100 bases:

>100_bases
TCCCTCTGACAGCGGAGAGCGCGCCATGAGAATCGTCCGCCTCGGTGCCGGCGCGGGCTATGCCGGGGACCGCATCGAGC
CCGCCGTCGAGCTCGCGGAG

Product: CitMHS family citrate/H+ symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MLALLGLCTIALLLAVILTKRMSPLVALIVIPVAAALIGGFGFETGKFVLAGLQSLAGVVGMFVFAILFFGIVSDAGMLD
PIIDRILARVGTRPTRIVPGTTLLALLIHLDGSGAVTFLITIPAMLPLYDRVGIDRRILACAASMAAGVNFLPWTGPMIR
ASAALKLPIPEIFSPLVPVQAVGLVFIFAVSYWLGLREERRLAHVPGAAGAAPGPAATARILSDAERTLRRPDRFWINLV
LTAAVLGTMVFLAEKVPPALMFMLGTALALVINYPQVDAQRQRIDAHARAAILMASILLAAGVFTGIMQGTGMLRAMAQT
AVTFVPPEMGRHIPFALGLVSMPLSMLFDPDSFYFGVLPVVAEVAHQLGVPPVQVAQGALLGQMTTGFPVSPLTPATFLV
CGLTGIDLADHQKFTFPFLLAASVVMTLTCVVLGVFPL

Sequences:

>Translated_438_residues
MLALLGLCTIALLLAVILTKRMSPLVALIVIPVAAALIGGFGFETGKFVLAGLQSLAGVVGMFVFAILFFGIVSDAGMLD
PIIDRILARVGTRPTRIVPGTTLLALLIHLDGSGAVTFLITIPAMLPLYDRVGIDRRILACAASMAAGVNFLPWTGPMIR
ASAALKLPIPEIFSPLVPVQAVGLVFIFAVSYWLGLREERRLAHVPGAAGAAPGPAATARILSDAERTLRRPDRFWINLV
LTAAVLGTMVFLAEKVPPALMFMLGTALALVINYPQVDAQRQRIDAHARAAILMASILLAAGVFTGIMQGTGMLRAMAQT
AVTFVPPEMGRHIPFALGLVSMPLSMLFDPDSFYFGVLPVVAEVAHQLGVPPVQVAQGALLGQMTTGFPVSPLTPATFLV
CGLTGIDLADHQKFTFPFLLAASVVMTLTCVVLGVFPL
>Mature_438_residues
MLALLGLCTIALLLAVILTKRMSPLVALIVIPVAAALIGGFGFETGKFVLAGLQSLAGVVGMFVFAILFFGIVSDAGMLD
PIIDRILARVGTRPTRIVPGTTLLALLIHLDGSGAVTFLITIPAMLPLYDRVGIDRRILACAASMAAGVNFLPWTGPMIR
ASAALKLPIPEIFSPLVPVQAVGLVFIFAVSYWLGLREERRLAHVPGAAGAAPGPAATARILSDAERTLRRPDRFWINLV
LTAAVLGTMVFLAEKVPPALMFMLGTALALVINYPQVDAQRQRIDAHARAAILMASILLAAGVFTGIMQGTGMLRAMAQT
AVTFVPPEMGRHIPFALGLVSMPLSMLFDPDSFYFGVLPVVAEVAHQLGVPPVQVAQGALLGQMTTGFPVSPLTPATFLV
CGLTGIDLADHQKFTFPFLLAASVVMTLTCVVLGVFPL

Specific function: Transports the free citrate anion. Probably cotransports citrate and at least three or four protons. The citrate uptake is inhibited by the presence of magnesium ions [H]

COG id: COG2851

COG function: function code C; H+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014738
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 46205; Mature: 46205

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALLGLCTIALLLAVILTKRMSPLVALIVIPVAAALIGGFGFETGKFVLAGLQSLAGVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GMFVFAILFFGIVSDAGMLDPIIDRILARVGTRPTRIVPGTTLLALLIHLDGSGAVTFLI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCEEHEE
TIPAMLPLYDRVGIDRRILACAASMAAGVNFLPWTGPMIRASAALKLPIPEIFSPLVPVQ
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEECCCHHHHCCCCHHH
AVGLVFIFAVSYWLGLREERRLAHVPGAAGAAPGPAATARILSDAERTLRRPDRFWINLV
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
LTAAVLGTMVFLAEKVPPALMFMLGTALALVINYPQVDAQRQRIDAHARAAILMASILLA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGVFTGIMQGTGMLRAMAQTAVTFVPPEMGRHIPFALGLVSMPLSMLFDPDSFYFGVLPV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
VAEVAHQLGVPPVQVAQGALLGQMTTGFPVSPLTPATFLVCGLTGIDLADHQKFTFPFLL
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHH
AASVVMTLTCVVLGVFPL
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLALLGLCTIALLLAVILTKRMSPLVALIVIPVAAALIGGFGFETGKFVLAGLQSLAGVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GMFVFAILFFGIVSDAGMLDPIIDRILARVGTRPTRIVPGTTLLALLIHLDGSGAVTFLI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCEEHEE
TIPAMLPLYDRVGIDRRILACAASMAAGVNFLPWTGPMIRASAALKLPIPEIFSPLVPVQ
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEECCCHHHHCCCCHHH
AVGLVFIFAVSYWLGLREERRLAHVPGAAGAAPGPAATARILSDAERTLRRPDRFWINLV
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
LTAAVLGTMVFLAEKVPPALMFMLGTALALVINYPQVDAQRQRIDAHARAAILMASILLA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGVFTGIMQGTGMLRAMAQTAVTFVPPEMGRHIPFALGLVSMPLSMLFDPDSFYFGVLPV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
VAEVAHQLGVPPVQVAQGALLGQMTTGFPVSPLTPATFLVCGLTGIDLADHQKFTFPFLL
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHH
AASVVMTLTCVVLGVFPL
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377; 7704256; 8892821 [H]