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The map label for this gene is cheB [H]

Identifier: 170750427

GI number: 170750427

Start: 4275599

End: 4276816

Strand: Reverse

Name: cheB [H]

Synonym: Mrad2831_4032

Alternate gene names: 170750427

Gene position: 4276816-4275599 (Counterclockwise)

Preceding gene: 170750428

Following gene: 170750426

Centisome position: 70.37

GC content: 75.86

Gene sequence:

>1218_bases
ATGGCCCTGAGTCCCGCGGTCGCCCCGCTGCGCACGCCGCCAACCCAGAGCACGACCTCATCGGCCACGGCGATCCGTGT
CCTGGTGGCCGACGATTCGGCCGTGGTGCGCGGCCTCGTCGCCCGCTGGATCGGCGAGGCCGGATTCGAGCTCGTCGGCA
CGGCCTCGAACGGCCGGATCGCCCTCGAGCTGATGGCCAAGCACGACCCGGACGTGGTCCTGCTCGACATCGAGATGCCG
GAACTCGACGGCACGACCGCGCTGCCGCGCATGCTCGCCATGAGCCCGAGCGTGCAGGTCGTGATGATGTCGACGCTGAC
GACGCGCAACGCCGACATCTCGCTGAAATGCCTCGCCCTCGGCGCGGTGGACTACATCGCCAAGCCGGAGAGCAGCCGCG
GCGTCACCACCTCGGACACGTTCCGGGTCGAGCTGATCGAGCGCGTCCGCGTGTTCGGCTCCGCCCGCGCGCGGAACCGG
CGCCCGGCCGCCGCGCCCGCCGGCCACGCCCCGGGGCACCACGCCGCGCCCGCACCCGTGGCCGTGCCGGCCGCGGCGCA
TCCGGCGCCGGCCGCCGCGGCGCGCCCGGCGACCCCCTTCACCCTGCGGCCCAAGGTCCGCAACCGGACCCAGCCCCGGG
CCCTGCTGATCGGCTCGTCCACGGGCGGGCCGCGGGCCGTGGGCGAGATGCTGGAGGGCATCGGCGCGGCCGCCCTGCGG
CGCCTGCCGGTCCTGATCGTCCAGCACATGCCGCCGATCTTCACGGCGGTCTTCGCCGAGCACCTGTCCACCCGCACCGG
GCTCCCGGCGGCCGAGGGCAAGGCCGAGGAGCGGGTCGAGCCGGGCCGCATCTACGTGGCCCCGGGCGGCCGCCACATGG
GGCTGGCCGCCGGGGCCGGCGGCCCGATCATCAAGCTCACCGACGGCCCGCCGGTGAATTTCTGCCGCCCCGCGGTCGAC
GTGCTGTTCAAGGACGCGGCGGTCGTGTTCGGCGCCGCCACCGCGACGGTGATCCTCACCGGCATGGGCTCGGACGGGAC
CAACGGCGCCCGGGCGCTCACCGAGGCCGGCGGCCCGGTCCTCGCCCAGGACGAGGCCACCAGCACGGTCTGGGGCATGC
CGGGCAGCGTCGCGCGGGCCGGGCTCGCCGAGGCCGTGCTGCCGCTGCCCGAGCTCGCGACGGCGCTGCGCGCCCTGATC
ACGGGGCAGCCGGCATGA

Upstream 100 bases:

>100_bases
GCCAAGCTCGAACAGGTCGGTCTCGTCGCCGACGCGGCCTGATCGCCCGCTCCCTGACCCGCGGCCCGAGCCCCGCGACC
CTGCACCCGAGGCAATCATC

Downstream 100 bases:

>100_bases
CCGAACTCGAGTTCGAATTCCTGCGCACCTTCCTGAAGCAGCGCTCCGGCCTCGCGCTGACGCCGGAGAAGCGCTACCTC
GTGGAGAGCCGGCTGACCCC

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MALSPAVAPLRTPPTQSTTSSATAIRVLVADDSAVVRGLVARWIGEAGFELVGTASNGRIALELMAKHDPDVVLLDIEMP
ELDGTTALPRMLAMSPSVQVVMMSTLTTRNADISLKCLALGAVDYIAKPESSRGVTTSDTFRVELIERVRVFGSARARNR
RPAAAPAGHAPGHHAAPAPVAVPAAAHPAPAAAARPATPFTLRPKVRNRTQPRALLIGSSTGGPRAVGEMLEGIGAAALR
RLPVLIVQHMPPIFTAVFAEHLSTRTGLPAAEGKAEERVEPGRIYVAPGGRHMGLAAGAGGPIIKLTDGPPVNFCRPAVD
VLFKDAAVVFGAATATVILTGMGSDGTNGARALTEAGGPVLAQDEATSTVWGMPGSVARAGLAEAVLPLPELATALRALI
TGQPA

Sequences:

>Translated_405_residues
MALSPAVAPLRTPPTQSTTSSATAIRVLVADDSAVVRGLVARWIGEAGFELVGTASNGRIALELMAKHDPDVVLLDIEMP
ELDGTTALPRMLAMSPSVQVVMMSTLTTRNADISLKCLALGAVDYIAKPESSRGVTTSDTFRVELIERVRVFGSARARNR
RPAAAPAGHAPGHHAAPAPVAVPAAAHPAPAAAARPATPFTLRPKVRNRTQPRALLIGSSTGGPRAVGEMLEGIGAAALR
RLPVLIVQHMPPIFTAVFAEHLSTRTGLPAAEGKAEERVEPGRIYVAPGGRHMGLAAGAGGPIIKLTDGPPVNFCRPAVD
VLFKDAAVVFGAATATVILTGMGSDGTNGARALTEAGGPVLAQDEATSTVWGMPGSVARAGLAEAVLPLPELATALRALI
TGQPA
>Mature_404_residues
ALSPAVAPLRTPPTQSTTSSATAIRVLVADDSAVVRGLVARWIGEAGFELVGTASNGRIALELMAKHDPDVVLLDIEMPE
LDGTTALPRMLAMSPSVQVVMMSTLTTRNADISLKCLALGAVDYIAKPESSRGVTTSDTFRVELIERVRVFGSARARNRR
PAAAPAGHAPGHHAAPAPVAVPAAAHPAPAAAARPATPFTLRPKVRNRTQPRALLIGSSTGGPRAVGEMLEGIGAAALRR
LPVLIVQHMPPIFTAVFAEHLSTRTGLPAAEGKAEERVEPGRIYVAPGGRHMGLAAGAGGPIIKLTDGPPVNFCRPAVDV
LFKDAAVVFGAATATVILTGMGSDGTNGARALTEAGGPVLAQDEATSTVWGMPGSVARAGLAEAVLPLPELATALRALIT
GQPA

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=381, Percent_Identity=35.1706036745407, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=40.7407407407407, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 41540; Mature: 41408

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSPAVAPLRTPPTQSTTSSATAIRVLVADDSAVVRGLVARWIGEAGFELVGTASNGRI
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCEE
ALELMAKHDPDVVLLDIEMPELDGTTALPRMLAMSPSVQVVMMSTLTTRNADISLKCLAL
EEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEHEECCCCEEEEEEEE
GAVDYIAKPESSRGVTTSDTFRVELIERVRVFGSARARNRRPAAAPAGHAPGHHAAPAPV
EHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE
AVPAAAHPAPAAAARPATPFTLRPKVRNRTQPRALLIGSSTGGPRAVGEMLEGIGAAALR
ECCCCCCCCCCCCCCCCCCEEECCHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
RLPVLIVQHMPPIFTAVFAEHLSTRTGLPAAEGKAEERVEPGRIYVAPGGRHMGLAAGAG
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEECCCCCEEEEEECCC
GPIIKLTDGPPVNFCRPAVDVLFKDAAVVFGAATATVILTGMGSDGTNGARALTEAGGPV
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHCCCCE
LAQDEATSTVWGMPGSVARAGLAEAVLPLPELATALRALITGQPA
EECCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALSPAVAPLRTPPTQSTTSSATAIRVLVADDSAVVRGLVARWIGEAGFELVGTASNGRI
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCEE
ALELMAKHDPDVVLLDIEMPELDGTTALPRMLAMSPSVQVVMMSTLTTRNADISLKCLAL
EEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEHEECCCCEEEEEEEE
GAVDYIAKPESSRGVTTSDTFRVELIERVRVFGSARARNRRPAAAPAGHAPGHHAAPAPV
EHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE
AVPAAAHPAPAAAARPATPFTLRPKVRNRTQPRALLIGSSTGGPRAVGEMLEGIGAAALR
ECCCCCCCCCCCCCCCCCCEEECCHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
RLPVLIVQHMPPIFTAVFAEHLSTRTGLPAAEGKAEERVEPGRIYVAPGGRHMGLAAGAG
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEECCCCCEEEEEECCC
GPIIKLTDGPPVNFCRPAVDVLFKDAAVVFGAATATVILTGMGSDGTNGARALTEAGGPV
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHCCCCE
LAQDEATSTVWGMPGSVARAGLAEAVLPLPELATALRALITGQPA
EECCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA