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The map label for this gene is 170750422

Identifier: 170750422

GI number: 170750422

Start: 4270852

End: 4271385

Strand: Reverse

Name: 170750422

Synonym: Mrad2831_4027

Alternate gene names: NA

Gene position: 4271385-4270852 (Counterclockwise)

Preceding gene: 170750423

Following gene: 170750419

Centisome position: 70.28

GC content: 73.78

Gene sequence:

>534_bases
ATGCCGCTGATCGACCCCGCCCGCTCGCTCCTCCTCGTCATCGACGTTCAGACCCGGCTGATGCCGGCGATCGCCGACGG
GGCCGGGGTCATCGCCAATACGGGCCGCCTCACCGCCGCCGCGAAGCTGCTCGACGTCCCGGTCCTGGTCACCGAGCAGA
ATGCCGGGGGCCTCGGGCCGACCGTGCCGGCCCTGGCGCCCGAGCCCGGGACGGCCTTCACCAAGATGAGCTTCGGCGCG
ACCCGGACGCCCGGCTTCCTGGAACGCCTGCCCGCGGACCGCGACCTCGTGGTCAGCGGCTGCGAGGCCCATGTCTGCGT
GCTGCAGACGGTTCTCGGCCTGCGCGAGGCCGGCCGCGGGGTCGCCGTGGTGGCCGACGCCGTGGGCTCGCGGCGGGTCG
AGAACCGGGAGGCCGCGCTCGCCCGGATGGCGGCCCACGGCGCCGAGATCGTCACCGCCGAGATGGTGGTGTTCGAGTGG
CTCGGCACGGCGCGACACAGGCGGTTCCGCGACGTGGTGAGGCTCATCAAGTAG

Upstream 100 bases:

>100_bases
TGCCGGCGGGCGCGGTCCCAAGCGGGCCCGATGGGGCGAGGATGCGGCGCGGGTGGCCCGCCCGTCCCCGTCGGGACCCG
TCCGGAGGGATCACAGACCC

Downstream 100 bases:

>100_bases
GCGCCGGGGCGGCGTCCGGGTCCCGCTGCGGAGCGCGCCTCAGGGGCCGTCGAGGGCCGCGCGGGTCTGCGGGTCGGGCC
CGATATCGTCGGTGCCGGTC

Product: isochorismatase hydrolase

Products: NA

Alternate protein names: Isochorismatase Family Protein; Isochorismatase Superfamily Hydrolase; Isochorismatase Hydrolase Family Protein; Nicotinamidase-Like Amidase; Isochorismatase Family Hydrolase; Hydrolase; Amidase; Amidohydrolase; Hydrolase Isochorismatase; Amidase Related Nicotinamidase; YcaC Like Amidohydrolase; Isochorismatase Family; Nicotinamidase; YcaC-Related Amidohydrolase; Isochorismatase Domain-Containing; Isochorismatase Domain-Containing A; Isochorismatase Hydrolase Family; Hydrolase Isochorismatase Family

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MPLIDPARSLLLVIDVQTRLMPAIADGAGVIANTGRLTAAAKLLDVPVLVTEQNAGGLGPTVPALAPEPGTAFTKMSFGA
TRTPGFLERLPADRDLVVSGCEAHVCVLQTVLGLREAGRGVAVVADAVGSRRVENREAALARMAAHGAEIVTAEMVVFEW
LGTARHRRFRDVVRLIK

Sequences:

>Translated_177_residues
MPLIDPARSLLLVIDVQTRLMPAIADGAGVIANTGRLTAAAKLLDVPVLVTEQNAGGLGPTVPALAPEPGTAFTKMSFGA
TRTPGFLERLPADRDLVVSGCEAHVCVLQTVLGLREAGRGVAVVADAVGSRRVENREAALARMAAHGAEIVTAEMVVFEW
LGTARHRRFRDVVRLIK
>Mature_176_residues
PLIDPARSLLLVIDVQTRLMPAIADGAGVIANTGRLTAAAKLLDVPVLVTEQNAGGLGPTVPALAPEPGTAFTKMSFGAT
RTPGFLERLPADRDLVVSGCEAHVCVLQTVLGLREAGRGVAVVADAVGSRRVENREAALARMAAHGAEIVTAEMVVFEWL
GTARHRRFRDVVRLIK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI209969695, Length=175, Percent_Identity=37.1428571428571, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI13376007, Length=191, Percent_Identity=34.0314136125654, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI103471987, Length=182, Percent_Identity=34.0659340659341, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17540156, Length=176, Percent_Identity=37.5, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21357489, Length=179, Percent_Identity=35.195530726257, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19922924, Length=176, Percent_Identity=34.0909090909091, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 18680; Mature: 18549

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLIDPARSLLLVIDVQTRLMPAIADGAGVIANTGRLTAAAKLLDVPVLVTEQNAGGLGP
CCCCCCCCCEEEEEECHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCEEEEECCCCCCCC
TVPALAPEPGTAFTKMSFGATRTPGFLERLPADRDLVVSGCEAHVCVLQTVLGLREAGRG
CCCCCCCCCCCCEEEECCCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
VAVVADAVGSRRVENREAALARMAAHGAEIVTAEMVVFEWLGTARHRRFRDVVRLIK
EEEEEHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PLIDPARSLLLVIDVQTRLMPAIADGAGVIANTGRLTAAAKLLDVPVLVTEQNAGGLGP
CCCCCCCCEEEEEECHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCEEEEECCCCCCCC
TVPALAPEPGTAFTKMSFGATRTPGFLERLPADRDLVVSGCEAHVCVLQTVLGLREAGRG
CCCCCCCCCCCCEEEECCCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
VAVVADAVGSRRVENREAALARMAAHGAEIVTAEMVVFEWLGTARHRRFRDVVRLIK
EEEEEHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA