Click here to switch to the map view.

The map label for this gene is sigK [H]

Identifier: 170750409

GI number: 170750409

Start: 4258880

End: 4259431

Strand: Reverse

Name: sigK [H]

Synonym: Mrad2831_4014

Alternate gene names: 170750409

Gene position: 4259431-4258880 (Counterclockwise)

Preceding gene: 170750411

Following gene: 170750408

Centisome position: 70.08

GC content: 66.3

Gene sequence:

>552_bases
TTGGCCGACGACGCCACGCTGCGCCGACTGCTCGCTGGTATCGCCCGGGGAGAGGCAAATCGGCTGGCCGAACTCTACGA
TCTCACGAGCCCGAAACTTTACGGCCTGATCCTGCGTATCCAGCGTGACCGTGGCTTGGCCGAGGACGTGCTTCAGGACG
TCTACATGCGCATCTGGCAGGCCGCGGGCAGCTACAAGCCCGAGGCCGGGCCGCCGCTGCCGTGGCTCTGCACCGTCGCC
CGCAATCGCGCCATCGACAGCGTACGGCGGAAGGTCGAGCATCAGGGCCCGGAATTGGATACCGGCGAGGATTGGGTGGC
GCGGCTGATCGATCCGCACGATGGGGCGGCAGATTTCATGGACCGGAGCGCCCTCCTGGCCTGCCTCGGCCGTCTCGACC
CCAAGCACCGGGACTGCGTCGTGCTGGCCTATTGCGAAGGGCAATCTCGGGAGGATTTGGCGCGGCACTTCGACCGGCCG
GTCAACACCATCAAGACTTGGCTGCACCGGTCACTCGCAGGCCTCAAGTCCTGCCTGGAGGCTGTCTCGTGA

Upstream 100 bases:

>100_bases
TATCGCGCGTGAGGGATCGTCACGGCTAGGCAGTTTGGGTTAAAGCAGCATCCGGTTGGGCGTCCGATAGAAGGCGCCTG
GGAGTTTGTAGGGAGCCAAC

Downstream 100 bases:

>100_bases
GCGGCAGCGGCCAGCCCGGCATGGACCCGACGTCCGAGCATGACATGCGCGCGGCCGAGTACGCCCTCGGGACACTCGAC
GCGCGGGAGCGGGCGGCGCT

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MADDATLRRLLAGIARGEANRLAELYDLTSPKLYGLILRIQRDRGLAEDVLQDVYMRIWQAAGSYKPEAGPPLPWLCTVA
RNRAIDSVRRKVEHQGPELDTGEDWVARLIDPHDGAADFMDRSALLACLGRLDPKHRDCVVLAYCEGQSREDLARHFDRP
VNTIKTWLHRSLAGLKSCLEAVS

Sequences:

>Translated_183_residues
MADDATLRRLLAGIARGEANRLAELYDLTSPKLYGLILRIQRDRGLAEDVLQDVYMRIWQAAGSYKPEAGPPLPWLCTVA
RNRAIDSVRRKVEHQGPELDTGEDWVARLIDPHDGAADFMDRSALLACLGRLDPKHRDCVVLAYCEGQSREDLARHFDRP
VNTIKTWLHRSLAGLKSCLEAVS
>Mature_182_residues
ADDATLRRLLAGIARGEANRLAELYDLTSPKLYGLILRIQRDRGLAEDVLQDVYMRIWQAAGSYKPEAGPPLPWLCTVAR
NRAIDSVRRKVEHQGPELDTGEDWVARLIDPHDGAADFMDRSALLACLGRLDPKHRDCVVLAYCEGQSREDLARHFDRPV
NTIKTWLHRSLAGLKSCLEAVS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 20559; Mature: 20428

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDATLRRLLAGIARGEANRLAELYDLTSPKLYGLILRIQRDRGLAEDVLQDVYMRIWQ
CCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAGSYKPEAGPPLPWLCTVARNRAIDSVRRKVEHQGPELDTGEDWVARLIDPHDGAADFM
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHH
DRSALLACLGRLDPKHRDCVVLAYCEGQSREDLARHFDRPVNTIKTWLHRSLAGLKSCLE
HHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AVS
HHC
>Mature Secondary Structure 
ADDATLRRLLAGIARGEANRLAELYDLTSPKLYGLILRIQRDRGLAEDVLQDVYMRIWQ
CCHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAGSYKPEAGPPLPWLCTVARNRAIDSVRRKVEHQGPELDTGEDWVARLIDPHDGAADFM
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHH
DRSALLACLGRLDPKHRDCVVLAYCEGQSREDLARHFDRPVNTIKTWLHRSLAGLKSCLE
HHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AVS
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA