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The map label for this gene is czcR [H]

Identifier: 170750394

GI number: 170750394

Start: 4248507

End: 4248872

Strand: Direct

Name: czcR [H]

Synonym: Mrad2831_3997

Alternate gene names: 170750394

Gene position: 4248507-4248872 (Clockwise)

Preceding gene: 170750393

Following gene: 170750395

Centisome position: 69.9

GC content: 69.95

Gene sequence:

>366_bases
ATGGCGCGCATCCTCCTGGTGGATGACGAAGAGACCGTCCGGGGCTTCCTCAAGCGGGGGCTCGAGATCGACGGGCACGC
GGTCGTCACGGCCAACGACGGCAGCGACGGACTCGACCGCCTCAACGAGGCCGACGGCGGCTTCGATCTGATGCTCACCG
ACATCCGCATGCCGCTCATGGACGGCATCGCGCTGGCCCTCGCCGCCAAGCGCGACTTCCCCGACCTGACCATCCTGCTG
ATGACCGGCTTCGCCGACCAGCGCGAGCGCGCGCGCGGGCTCGACGCCATCGTCACCGACGTGCTGACCAAGCCCTTCTC
CCTGGCGGATCTCCGCGCCACCGTGAAGCGGGCGCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
GACTTGACAGACGGGGAATTCGTCTGTGTCTGTCGGCGTTTGGGCGCGCGCGCCGTCGCGACGGGTCGCGCGCGGATTTC
GGGGACGGTTACGGGACCAC

Downstream 100 bases:

>100_bases
CCTGGGCGGGATCGGTTCGGAAGAACTTAAACATTGCTCTTAGGTTGAGCTTCACGAAAGCGTGGCACCTTCGGTCCGAC
TGGATCAGACCGAGCACGGA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MARILLVDDEETVRGFLKRGLEIDGHAVVTANDGSDGLDRLNEADGGFDLMLTDIRMPLMDGIALALAAKRDFPDLTILL
MTGFADQRERARGLDAIVTDVLTKPFSLADLRATVKRALAA

Sequences:

>Translated_121_residues
MARILLVDDEETVRGFLKRGLEIDGHAVVTANDGSDGLDRLNEADGGFDLMLTDIRMPLMDGIALALAAKRDFPDLTILL
MTGFADQRERARGLDAIVTDVLTKPFSLADLRATVKRALAA
>Mature_120_residues
ARILLVDDEETVRGFLKRGLEIDGHAVVTANDGSDGLDRLNEADGGFDLMLTDIRMPLMDGIALALAAKRDFPDLTILLM
TGFADQRERARGLDAIVTDVLTKPFSLADLRATVKRALAA

Specific function: Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt, zinc and cadmium homeostasis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=39.8305084745763, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=35.4838709677419, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=35.8974358974359, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=34.4827586206897, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13126; Mature: 12995

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARILLVDDEETVRGFLKRGLEIDGHAVVTANDGSDGLDRLNEADGGFDLMLTDIRMPLM
CCEEEEECCHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEEHHHHHHHH
DGIALALAAKRDFPDLTILLMTGFADQRERARGLDAIVTDVLTKPFSLADLRATVKRALA
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHC
A
C
>Mature Secondary Structure 
ARILLVDDEETVRGFLKRGLEIDGHAVVTANDGSDGLDRLNEADGGFDLMLTDIRMPLM
CEEEEECCHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEEHHHHHHHH
DGIALALAAKRDFPDLTILLMTGFADQRERARGLDAIVTDVLTKPFSLADLRATVKRALA
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9044283 [H]