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The map label for this gene is cdd [H]

Identifier: 170750323

GI number: 170750323

Start: 4176530

End: 4176892

Strand: Reverse

Name: cdd [H]

Synonym: Mrad2831_3926

Alternate gene names: 170750323

Gene position: 4176892-4176530 (Counterclockwise)

Preceding gene: 170750324

Following gene: 170750322

Centisome position: 68.72

GC content: 76.58

Gene sequence:

>363_bases
GTGCGCGCGCACGCGCACGCACCCTATTCCCGCTTCCCGGTCGGGGCCGCGCTGCGCGACGAGGGCGGCGCGATCCACGC
CGGCTGCAACGTCGAGAACGCCGCCTACCCGGTCGGAACCTGCGCGGAGGCCGGGGCGATCGCCGCCATGGTGGCGGCCG
GAGGCCGGCGCATCGCGGCGATCCTGGTCTGCGGCGACGGCAACGGCCCGGTGACGCCCTGCGGCGCCTGCCGCCAGCGC
ATCCGCGAGTTCGCCGGGCCGGACACCCCGATCCACACCGCCGGTCCGGGCGGCGTCGCCCGCAGCTTCACCCTGGCGGA
GCTGCTGCCGGAATCCTTCGGCCCGGAGACGCTCGGTGAGTGA

Upstream 100 bases:

>100_bases
CGGCGGGTGCCAAAGATCGGCCATGCAGGCCGCGGATCCAGCACGGGACCCAGCAGGGGACGATGACGGGCTCGCAGCCC
TGTTCGAGGCGGCGCGCGCG

Downstream 100 bases:

>100_bases
GGCGGCCGCCCGCGACGCCCTGCGCGCCGCCGGCTTCGCGGGTCCCTACGCCTGCGCGGTGGTGACCGGCACCGGCCTCG
GCGGGATCGCGGCGGCCCTC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MRAHAHAPYSRFPVGAALRDEGGAIHAGCNVENAAYPVGTCAEAGAIAAMVAAGGRRIAAILVCGDGNGPVTPCGACRQR
IREFAGPDTPIHTAGPGGVARSFTLAELLPESFGPETLGE

Sequences:

>Translated_120_residues
MRAHAHAPYSRFPVGAALRDEGGAIHAGCNVENAAYPVGTCAEAGAIAAMVAAGGRRIAAILVCGDGNGPVTPCGACRQR
IREFAGPDTPIHTAGPGGVARSFTLAELLPESFGPETLGE
>Mature_120_residues
MRAHAHAPYSRFPVGAALRDEGGAIHAGCNVENAAYPVGTCAEAGAIAAMVAAGGRRIAAILVCGDGNGPVTPCGACRQR
IREFAGPDTPIHTAGPGGVARSFTLAELLPESFGPETLGE

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=120, Percent_Identity=47.5, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540514, Length=114, Percent_Identity=46.4912280701754, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17551074, Length=117, Percent_Identity=36.7521367521368, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323274, Length=118, Percent_Identity=39.8305084745763, Blast_Score=89, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582741, Length=118, Percent_Identity=41.5254237288136, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920920, Length=96, Percent_Identity=50, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582744, Length=94, Percent_Identity=47.8723404255319, Blast_Score=85, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 12067; Mature: 12067

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAHAHAPYSRFPVGAALRDEGGAIHAGCNVENAAYPVGTCAEAGAIAAMVAAGGRRIAA
CCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEE
ILVCGDGNGPVTPCGACRQRIREFAGPDTPIHTAGPGGVARSFTLAELLPESFGPETLGE
EEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRAHAHAPYSRFPVGAALRDEGGAIHAGCNVENAAYPVGTCAEAGAIAAMVAAGGRRIAA
CCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEE
ILVCGDGNGPVTPCGACRQRIREFAGPDTPIHTAGPGGVARSFTLAELLPESFGPETLGE
EEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]