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The map label for this gene is bphG [H]

Identifier: 170750276

GI number: 170750276

Start: 4127185

End: 4128510

Strand: Direct

Name: bphG [H]

Synonym: Mrad2831_3879

Alternate gene names: 170750276

Gene position: 4127185-4128510 (Clockwise)

Preceding gene: 170750275

Following gene: 170750277

Centisome position: 67.91

GC content: 77.22

Gene sequence:

>1326_bases
GTGACTCCCGAACCCGCCGGCATCGTCGTGGTCGGGGCCTCCCTCGCCGGCCTGCGCGGTGCCGAGGCGCTGCGGCGGGG
CGGCTACGACGGGCCGCTCACCCTGGTCGGCGCCGAGCCGTACCGCCCCTACGACCGCCCGCCCCTGTCGAAGCACGTGC
TCGCCGGGGAGCTCGCCGCCGACGCGACCCGGCTGCCGGAACTGGCCGAGCTCCGCGCCCGCTGGCGTCTCGGGAGCCCG
GCCGTCGCCCTCGACCGGGCGGCCCGCACGCTCCGGCTCGCCGACGGGTCGACGCTCGCCTACGAGTCCCTGCTCATCGC
CACCGGCGCCGAGGCCCGGCCCTGGCCGGCCGAGACCGGTGGCGGGCTCGCCGGCATCTTCACCCTGCGCGGGCGCGACG
ACGCGGCCGCCCTGCGGGACGCCCTGGTGGCGCGCCCGCGGCAGGTGCTGATCGTGGGCGGCGGCCTGATCGGCTGCGAG
GCGGCCTCCTGCCTGCGCGATCTGGGCCTGCCCGTGACCCTGGTCGACCCGAACGCCGCGCCCCTGGCCCGGGGTCTCGG
GACCTTCGTCGGCAGCGTGATCGCCGAGTGCCTGCGCGCGTCCGGCGCCACGTTCCGCCCCGGCGCGACGGTGCGGGCGT
TCGAGGGCGACGCGTCCGGGCACGTCGCCCGGGCCCGCCTGGCGGACGGCAGCACCATCGAGACCAACCTGGTCATCGTC
GCCCTGGGGGCGACCCGGGCGACGGGCTGGCTGCGGGGTGCGGGCCTGCGCGCGGATGCCGGCGGGGTGACCTGCGACGC
GGCCTGCCGGGTCCTCGACGCCGACAGGGTGCCCTGCCCGGACATCTACGCCGCGGGCGACGTCGCCCGGTGGCCGATCC
CCCTCTACGGCAACCGCCTGATCGCCGTGGAGCACTGGGGCAACGCCGTCGAGCAGGCCGCGCACGCGGCGCGCAACATG
CTGGCCGACCCCGGCGACCAGCGCCCCTACGGTCACCTTCCGGCCTTCTGGTCGAGCCAGTTCGGGATCAACATCAAGCT
GGTCGGCCTCCCCGACGGGGCCGATTCCGTGGCGGTGGTGCAGGGTTCGCGGGCCTCCCGGCGCTTCCTCGCCGTATACG
GCCGCGCCGGGCGCAGCATCGCGGCCGTCTCGTTCGATCAGGCCCGCTGGCTGCCGGCCTACGCGGAGGCGATCACGGCC
GGCGATCCGTTCCCGCCGATCACCGACGCCACCGACCGGCCGCGCGTCGAGATGGCGGTCCCGGGCTTCCCGCCGCCGCA
CCGAGCCGCCGAGGCGCGGCCTTCCGCCGAGACCGTCCATGTCTGA

Upstream 100 bases:

>100_bases
CGCCGCCGGCCGAGCGGCGCGGCGCCATCGAGCGGGCGCTGCAGGCCTGCCCGGTCCGCGCCATCAGCCTCCAGGCCGGC
CCGGACGACGGGGGCGCGCC

Downstream 100 bases:

>100_bases
CGACGCGCTGTTCGCCGCCGTGATGGATCCGGCCAACCGGGCCGACCCGTACCCGCTCTATCGACGGATGCGGCAGCAGC
CGGTCTCGCGCCAGCGCGAC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTPEPAGIVVVGASLAGLRGAEALRRGGYDGPLTLVGAEPYRPYDRPPLSKHVLAGELAADATRLPELAELRARWRLGSP
AVALDRAARTLRLADGSTLAYESLLIATGAEARPWPAETGGGLAGIFTLRGRDDAAALRDALVARPRQVLIVGGGLIGCE
AASCLRDLGLPVTLVDPNAAPLARGLGTFVGSVIAECLRASGATFRPGATVRAFEGDASGHVARARLADGSTIETNLVIV
ALGATRATGWLRGAGLRADAGGVTCDAACRVLDADRVPCPDIYAAGDVARWPIPLYGNRLIAVEHWGNAVEQAAHAARNM
LADPGDQRPYGHLPAFWSSQFGINIKLVGLPDGADSVAVVQGSRASRRFLAVYGRAGRSIAAVSFDQARWLPAYAEAITA
GDPFPPITDATDRPRVEMAVPGFPPPHRAAEARPSAETVHV

Sequences:

>Translated_441_residues
MTPEPAGIVVVGASLAGLRGAEALRRGGYDGPLTLVGAEPYRPYDRPPLSKHVLAGELAADATRLPELAELRARWRLGSP
AVALDRAARTLRLADGSTLAYESLLIATGAEARPWPAETGGGLAGIFTLRGRDDAAALRDALVARPRQVLIVGGGLIGCE
AASCLRDLGLPVTLVDPNAAPLARGLGTFVGSVIAECLRASGATFRPGATVRAFEGDASGHVARARLADGSTIETNLVIV
ALGATRATGWLRGAGLRADAGGVTCDAACRVLDADRVPCPDIYAAGDVARWPIPLYGNRLIAVEHWGNAVEQAAHAARNM
LADPGDQRPYGHLPAFWSSQFGINIKLVGLPDGADSVAVVQGSRASRRFLAVYGRAGRSIAAVSFDQARWLPAYAEAITA
GDPFPPITDATDRPRVEMAVPGFPPPHRAAEARPSAETVHV
>Mature_440_residues
TPEPAGIVVVGASLAGLRGAEALRRGGYDGPLTLVGAEPYRPYDRPPLSKHVLAGELAADATRLPELAELRARWRLGSPA
VALDRAARTLRLADGSTLAYESLLIATGAEARPWPAETGGGLAGIFTLRGRDDAAALRDALVARPRQVLIVGGGLIGCEA
ASCLRDLGLPVTLVDPNAAPLARGLGTFVGSVIAECLRASGATFRPGATVRAFEGDASGHVARARLADGSTIETNLVIVA
LGATRATGWLRGAGLRADAGGVTCDAACRVLDADRVPCPDIYAAGDVARWPIPLYGNRLIAVEHWGNAVEQAAHAARNML
ADPGDQRPYGHLPAFWSSQFGINIKLVGLPDGADSVAVVQGSRASRRFLAVYGRAGRSIAAVSFDQARWLPAYAEAITAG
DPFPPITDATDRPRVEMAVPGFPPPHRAAEARPSAETVHV

Specific function: Part of the electron transfer component of biphenyl dioxygenase, transfers electrons from ferredoxin (BphF) to NADH [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=405, Percent_Identity=28.1481481481481, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI226437568, Length=405, Percent_Identity=28.1481481481481, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI65787454, Length=405, Percent_Identity=28.1481481481481, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI22202629, Length=339, Percent_Identity=27.7286135693215, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4757732, Length=339, Percent_Identity=27.7286135693215, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1788892, Length=399, Percent_Identity=31.5789473684211, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789065, Length=290, Percent_Identity=32.4137931034483, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789765, Length=299, Percent_Identity=27.0903010033445, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=399, Percent_Identity=25.8145363408521, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24639257, Length=401, Percent_Identity=25.9351620947631, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281359715, Length=401, Percent_Identity=25.9351620947631, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281359713, Length=401, Percent_Identity=25.9351620947631, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24639250, Length=401, Percent_Identity=25.9351620947631, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI18543267, Length=401, Percent_Identity=25.9351620947631, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24639252, Length=401, Percent_Identity=25.9351620947631, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24585130, Length=397, Percent_Identity=27.2040302267003, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28573993, Length=374, Percent_Identity=25.9358288770053, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24581020, Length=374, Percent_Identity=25.9358288770053, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.3 [H]

Molecular weight: Translated: 45911; Mature: 45779

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEPAGIVVVGASLAGLRGAEALRRGGYDGPLTLVGAEPYRPYDRPPLSKHVLAGELAA
CCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
DATRLPELAELRARWRLGSPAVALDRAARTLRLADGSTLAYESLLIATGAEARPWPAETG
HHHCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCEEHHHEEEEECCCCCCCCCCCCC
GGLAGIFTLRGRDDAAALRDALVARPRQVLIVGGGLIGCEAASCLRDLGLPVTLVDPNAA
CCEEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHCCCCEEEECCCCH
PLARGLGTFVGSVIAECLRASGATFRPGATVRAFEGDASGHVARARLADGSTIETNLVIV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEECEEEEE
ALGATRATGWLRGAGLRADAGGVTCDAACRVLDADRVPCPDIYAAGDVARWPIPLYGNRL
EECCCCCCCHHCCCCCCCCCCCCCHHHHHHEECCCCCCCCCCEECCCCCCCCCCCCCCEE
IAVEHWGNAVEQAAHAARNMLADPGDQRPYGHLPAFWSSQFGINIKLVGLPDGADSVAVV
EEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEE
QGSRASRRFLAVYGRAGRSIAAVSFDQARWLPAYAEAITAGDPFPPITDATDRPRVEMAV
ECCCCCCEEEEEECCCCCEEEEEECCCHHCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
PGFPPPHRAAEARPSAETVHV
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPEPAGIVVVGASLAGLRGAEALRRGGYDGPLTLVGAEPYRPYDRPPLSKHVLAGELAA
CCCCCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
DATRLPELAELRARWRLGSPAVALDRAARTLRLADGSTLAYESLLIATGAEARPWPAETG
HHHCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCEEHHHEEEEECCCCCCCCCCCCC
GGLAGIFTLRGRDDAAALRDALVARPRQVLIVGGGLIGCEAASCLRDLGLPVTLVDPNAA
CCEEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHCCCCEEEECCCCH
PLARGLGTFVGSVIAECLRASGATFRPGATVRAFEGDASGHVARARLADGSTIETNLVIV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEEECEEEEE
ALGATRATGWLRGAGLRADAGGVTCDAACRVLDADRVPCPDIYAAGDVARWPIPLYGNRL
EECCCCCCCHHCCCCCCCCCCCCCHHHHHHEECCCCCCCCCCEECCCCCCCCCCCCCCEE
IAVEHWGNAVEQAAHAARNMLADPGDQRPYGHLPAFWSSQFGINIKLVGLPDGADSVAVV
EEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEE
QGSRASRRFLAVYGRAGRSIAAVSFDQARWLPAYAEAITAGDPFPPITDATDRPRVEMAV
ECCCCCCEEEEEECCCCCEEEEEECCCHHCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
PGFPPPHRAAEARPSAETVHV
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1569021 [H]