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The map label for this gene is sugE [H]

Identifier: 170750223

GI number: 170750223

Start: 4069412

End: 4069732

Strand: Reverse

Name: sugE [H]

Synonym: Mrad2831_3825

Alternate gene names: 170750223

Gene position: 4069732-4069412 (Counterclockwise)

Preceding gene: 170750224

Following gene: 170750217

Centisome position: 66.96

GC content: 70.4

Gene sequence:

>321_bases
ATGGCCTGGATCTATCTCGTCATCGCGGGCCTGCTGGAGGTCGTCTGGGCCTTCGCGATGAAGCAGTCGGACGGCTTCAC
GCGCGTCTGGCCGACCGCCATCATGGCCGTATCGATGGCCGGCAGCGTCGGCTTCCTGGCGCTGGCCATGCGCACGCTGC
CGCTGGGAACCGCCTACACGGTCTGGACCGGCATCGGCGCGGTCGGCGCCTTCCTGGTCGGCATTGCCGTCCTCGGGGAG
CAGGCGAGCGCCGGCCGCATCCTCGCCGCCGGCCTGATCGGCTCCGGGCTCGTCCTGATGAAGCTGTCGAGCCCCGGCTG
A

Upstream 100 bases:

>100_bases
TTGGCCGATCATCGCTAGCTGACCCGCCGCGAGGCCACGTCCTCCCCCCGTCGCGCGGGGCACAAGTCCGGGACGGCCCG
GCCCTTTCCGGAGGGCCGCC

Downstream 100 bases:

>100_bases
GCGTCAGGCGGCGCGCACCGTGTGCAGGAAGGCGTCGATCTCCCGGCGCAGCTCGGCGGCTTCCTCCGAGAGGCTCGACG
CCGAGGCCAGCATCCGCGTG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MAWIYLVIAGLLEVVWAFAMKQSDGFTRVWPTAIMAVSMAGSVGFLALAMRTLPLGTAYTVWTGIGAVGAFLVGIAVLGE
QASAGRILAAGLIGSGLVLMKLSSPG

Sequences:

>Translated_106_residues
MAWIYLVIAGLLEVVWAFAMKQSDGFTRVWPTAIMAVSMAGSVGFLALAMRTLPLGTAYTVWTGIGAVGAFLVGIAVLGE
QASAGRILAAGLIGSGLVLMKLSSPG
>Mature_105_residues
AWIYLVIAGLLEVVWAFAMKQSDGFTRVWPTAIMAVSMAGSVGFLALAMRTLPLGTAYTVWTGIGAVGAFLVGIAVLGEQ
ASAGRILAAGLIGSGLVLMKLSSPG

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=53.8461538461538, Blast_Score=103, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10858; Mature: 10727

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIYLVIAGLLEVVWAFAMKQSDGFTRVWPTAIMAVSMAGSVGFLALAMRTLPLGTAYT
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHH
VWTGIGAVGAFLVGIAVLGEQASAGRILAAGLIGSGLVLMKLSSPG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCCEEEEEECCCC
>Mature Secondary Structure 
AWIYLVIAGLLEVVWAFAMKQSDGFTRVWPTAIMAVSMAGSVGFLALAMRTLPLGTAYT
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHH
VWTGIGAVGAFLVGIAVLGEQASAGRILAAGLIGSGLVLMKLSSPG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]