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The map label for this gene is corA [H]

Identifier: 170750221

GI number: 170750221

Start: 4066621

End: 4067625

Strand: Direct

Name: corA [H]

Synonym: Mrad2831_3823

Alternate gene names: 170750221

Gene position: 4066621-4067625 (Clockwise)

Preceding gene: 170750220

Following gene: 170750222

Centisome position: 66.91

GC content: 65.87

Gene sequence:

>1005_bases
GTGATCTTCATCCACCAGCCCGCCGTCGGCGCCGGAGCCACGCTGCTTGAGCGCCGCGTCATCGATCTCCAGGACACGAT
CCCCGAGGACACGGTCTGGCTCGACCTGATCCGCCCGAGCCGCGAGGAGGAACTGAAGGTCGAGTCGTTCGCGGGCATCG
AGGTGCCGACCCGCGAGGAGATGAAGGACATCGAGCCCTCGGAGCTGCTCTACGTCGAGGACGGCGCCCGCTACATGACC
GGCCGGGTGCTCTCGAAGGTCAGCGACGCCGAGGAGCCGGGGCTGGCCGGCATCACCTTCATCCTGCGCGGCAACCGGCT
GGTGACCGTGCGCCACGAGGAGCCGCAGGCCTTCCGCATGTACACGCAGCGCGCCGGGCGCTCGATGGGCAACGGCGGCG
CGTCGACGCCCTCGGGCGAGTCGATCCTGGCCGGGCTGATCGAGGCGGTGATCGACCGGGCCGCCGACGTGCTGCAGCTC
CAGGGCGAGCGCATCGACCGCCTGTCGGGCAAGATCTTCGAAGTGCAGGAGGACCCCTCCGCGCGCAACACAGCGCTGCA
GGACACGTTGCGCGCCCTCGGCCGGCACGGCGATCTCATCTCCAAGCAGCGGGAAAGTCTCGTCTCCATGGAGCGGATCC
TGCTCTCGCTGTCGGCGACCTACCGGACCAACAAGGCCCCGCGCGACCTGCGCGAGGATGTGCGCTCGACCCTGCGGGAT
CTCCAGTCCCTGGAGGAGCACGCGACCTTCCTGTCGACGAAGATCCAGTTCCTGCTCGACGCGACCCTCGGGCTCGTCAA
CCTCGAGCAGAACAACATCATCAAGCTGTTCTCGGTCATGGCCGTCGTCTTCATGCCGCCGACCCTGATCGCGTCGATCT
ACGGCATGAATTTTAAGTCCATACCGGAACTAGATTTCGCATTCGGATACCCGATGGCGCTGATCATGATGGTCGTGGCC
GCCGTATTCCCCTACTTCTTCTTCCGCTGGAAGAAGTGGCTCTGA

Upstream 100 bases:

>100_bases
GCGCCACATCCGCGGCACAGCTTGCATCGGCCACCGTGGTGCCGGATGCGGGCTGCGGCCCCGCGCTGTCCCGTGACCGA
CCCGCATCCGAGACCCGTAC

Downstream 100 bases:

>100_bases
CAACAAATGCTGGTCTAGAGCCGATAGAATTTTAAGACCTCTGCGGGAGCATGGTGGGGCCTGAAGGCGCGGCGCGGCCG
CGAGGACGGAATCTCCCATG

Product: Mg2 transporter protein CorA family protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIFIHQPAVGAGATLLERRVIDLQDTIPEDTVWLDLIRPSREEELKVESFAGIEVPTREEMKDIEPSELLYVEDGARYMT
GRVLSKVSDAEEPGLAGITFILRGNRLVTVRHEEPQAFRMYTQRAGRSMGNGGASTPSGESILAGLIEAVIDRAADVLQL
QGERIDRLSGKIFEVQEDPSARNTALQDTLRALGRHGDLISKQRESLVSMERILLSLSATYRTNKAPRDLREDVRSTLRD
LQSLEEHATFLSTKIQFLLDATLGLVNLEQNNIIKLFSVMAVVFMPPTLIASIYGMNFKSIPELDFAFGYPMALIMMVVA
AVFPYFFFRWKKWL

Sequences:

>Translated_334_residues
MIFIHQPAVGAGATLLERRVIDLQDTIPEDTVWLDLIRPSREEELKVESFAGIEVPTREEMKDIEPSELLYVEDGARYMT
GRVLSKVSDAEEPGLAGITFILRGNRLVTVRHEEPQAFRMYTQRAGRSMGNGGASTPSGESILAGLIEAVIDRAADVLQL
QGERIDRLSGKIFEVQEDPSARNTALQDTLRALGRHGDLISKQRESLVSMERILLSLSATYRTNKAPRDLREDVRSTLRD
LQSLEEHATFLSTKIQFLLDATLGLVNLEQNNIIKLFSVMAVVFMPPTLIASIYGMNFKSIPELDFAFGYPMALIMMVVA
AVFPYFFFRWKKWL
>Mature_334_residues
MIFIHQPAVGAGATLLERRVIDLQDTIPEDTVWLDLIRPSREEELKVESFAGIEVPTREEMKDIEPSELLYVEDGARYMT
GRVLSKVSDAEEPGLAGITFILRGNRLVTVRHEEPQAFRMYTQRAGRSMGNGGASTPSGESILAGLIEAVIDRAADVLQL
QGERIDRLSGKIFEVQEDPSARNTALQDTLRALGRHGDLISKQRESLVSMERILLSLSATYRTNKAPRDLREDVRSTLRD
LQSLEEHATFLSTKIQFLLDATLGLVNLEQNNIIKLFSVMAVVFMPPTLIASIYGMNFKSIPELDFAFGYPMALIMMVVA
AVFPYFFFRWKKWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=307, Percent_Identity=37.1335504885993, Blast_Score=187, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37581; Mature: 37581

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFIHQPAVGAGATLLERRVIDLQDTIPEDTVWLDLIRPSREEELKVESFAGIEVPTREE
CEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHH
MKDIEPSELLYVEDGARYMTGRVLSKVSDAEEPGLAGITFILRGNRLVTVRHEEPQAFRM
HHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCCHHHHH
YTQRAGRSMGNGGASTPSGESILAGLIEAVIDRAADVLQLQGERIDRLSGKIFEVQEDPS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
ARNTALQDTLRALGRHGDLISKQRESLVSMERILLSLSATYRTNKAPRDLREDVRSTLRD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LQSLEEHATFLSTKIQFLLDATLGLVNLEQNNIIKLFSVMAVVFMPPTLIASIYGMNFKS
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCC
IPELDFAFGYPMALIMMVVAAVFPYFFFRWKKWL
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFIHQPAVGAGATLLERRVIDLQDTIPEDTVWLDLIRPSREEELKVESFAGIEVPTREE
CEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHH
MKDIEPSELLYVEDGARYMTGRVLSKVSDAEEPGLAGITFILRGNRLVTVRHEEPQAFRM
HHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCCHHHHH
YTQRAGRSMGNGGASTPSGESILAGLIEAVIDRAADVLQLQGERIDRLSGKIFEVQEDPS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
ARNTALQDTLRALGRHGDLISKQRESLVSMERILLSLSATYRTNKAPRDLREDVRSTLRD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LQSLEEHATFLSTKIQFLLDATLGLVNLEQNNIIKLFSVMAVVFMPPTLIASIYGMNFKS
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCC
IPELDFAFGYPMALIMMVVAAVFPYFFFRWKKWL
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]