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The map label for this gene is cusB [H]

Identifier: 170750210

GI number: 170750210

Start: 4054874

End: 4056370

Strand: Direct

Name: cusB [H]

Synonym: Mrad2831_3812

Alternate gene names: 170750210

Gene position: 4054874-4056370 (Clockwise)

Preceding gene: 170750209

Following gene: 170750211

Centisome position: 66.72

GC content: 75.95

Gene sequence:

>1497_bases
GTGAGCCGCACCGCCTGGTTCGCCGGGGCCCTCGCCGCGCTCGCGGCGGGGGGTATCGGCTACGGCGCGGGGCACGGGGG
CGACCCCGTGCCGGCGCTGGTCGCGGCCGCCCGGACGCGGTTCGCCGCGTGGCGGCCGAGCGGTCCGGCCCCGTCCGTCC
CGGCCCCGTCCGTCCCGGCGCCGAATGCGGCGGCGACCGGCCCGGTGGTCTACTACCGGGATCCGGACGGGAAGCCGGTC
TACTCGCTGGCGCCGATGATGACCGCGGACGGGCGCGAGTTCCGGCCGGTGCGCGCCAGCGAGGACGTCCGCTTCGATCT
CCCGGACGACGTTCCCGGCCCCGACACGGCCGGCGCGGAGGCCGCCGGCCACCGGCCCGATTCCGGCACGCGCGCGATCC
TCTACTACCGCAACCCGATGGGCCTGCCGGACACGTCGCCGGTGCCGAAGAAGGACTCGATGGGGATGGACTACATCCCC
GTCTACGCCGACGCGGAGGCGGGCGGCCCGGTCGTGACGGTCCCGGCCGGCCGGATCCAGCGCACCGGCGTGCGGATCGC
GACCGCCGAGCGGCGGGTGGTGGCGCAGCCGGTGCGCGTGCCCGGCACGCTGGCCCTCGACGAGCGCCGCGTCACCGTCG
TGGCGACGCGCTCCGACGCCTATGTCGACCGGGTCGAGAGCGTCACGACCGGGGACCGGGTCCGCCGCGGCCAGCCCCTG
GTCCACGTCTACTCGCCGGAGATCAACGCGGCCGCGGCCCAGCTCATCGCCAATCCCGGCTTCGACGGCGCTCGCCGGCG
GCTGCAGAACCTCAACGTCTCCGCGGACGTCATCGACGCGATGGAGCGCACCCGCACGGTGCCGATGGCCATCACGTGGT
CCTCGCCCCGGGACGGCATCGTCCTGCAGCGGAACGCCGTGGAGGGCATGAAGGCCGCGGCCGGCGACACCCTGTTCCGC
ATCGCCGACATCGCGGTGCTGTGGGTACTGGCCGACGTGCCCGAGCGCGACCTCGCGGGGATCCGCGTCGGCCAAGTCGC
GACCGTGCGCCCGCGCTCCGCGCCGGGCCGGACCGTCACCGGCCGGGTGGCGGTGATCTACCCGCAGGTGAATCCCGAGA
CCCGCGCCACCCGGGTGCGGATCGAGCTGCCGAATCCGGACGGCACGCTCCTGCCGGACATGTACGCCGACGTCGCGATC
GCGACGGGGAGCGCCGAGCCGGTGGTGGCGGTCCCGGACGACGCCGTCCTCGACACCGGCACGCGCCAGGTCGTGCTGCT
CGAGCGCGGCGAGGGCCGCTTCGAGCCGCGGGCCGTGACCCTCGGCGCGCGGGGCGAGGGCTTCACCGAGATCCGCGCCG
GCCTCGCGGCCGGCGACCGGGTGGTCACGGCGGCGAACTTCCTGATCGACGCCGAGAGCAACCTGAAGGCGGCACTTCAG
AGCCTCGCCCCGCCGCGGGACGACCGGCAGGCCGCCCGTGCGGGAGATGCCCCGTGA

Upstream 100 bases:

>100_bases
CCAAGCTCTCGATGCAGGGCCGCTGGCGCCTGTCGCTCGCCGCGAAGGTCCAGGGTGAGACCGGCACGGTCGACGACCAG
CTGATCGTCCAGGCCGCCAA

Downstream 100 bases:

>100_bases
TCGCCCGCCTCATAGACTGGTCGGCCCGCAACCTGGTCCTGGTGCTGGTCGGGACAGCGCTGGCGGTCGGCGCCGGCCTC
GTGGCCCTCCGGACGCTGCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MSRTAWFAGALAALAAGGIGYGAGHGGDPVPALVAAARTRFAAWRPSGPAPSVPAPSVPAPNAAATGPVVYYRDPDGKPV
YSLAPMMTADGREFRPVRASEDVRFDLPDDVPGPDTAGAEAAGHRPDSGTRAILYYRNPMGLPDTSPVPKKDSMGMDYIP
VYADAEAGGPVVTVPAGRIQRTGVRIATAERRVVAQPVRVPGTLALDERRVTVVATRSDAYVDRVESVTTGDRVRRGQPL
VHVYSPEINAAAAQLIANPGFDGARRRLQNLNVSADVIDAMERTRTVPMAITWSSPRDGIVLQRNAVEGMKAAAGDTLFR
IADIAVLWVLADVPERDLAGIRVGQVATVRPRSAPGRTVTGRVAVIYPQVNPETRATRVRIELPNPDGTLLPDMYADVAI
ATGSAEPVVAVPDDAVLDTGTRQVVLLERGEGRFEPRAVTLGARGEGFTEIRAGLAAGDRVVTAANFLIDAESNLKAALQ
SLAPPRDDRQAARAGDAP

Sequences:

>Translated_498_residues
MSRTAWFAGALAALAAGGIGYGAGHGGDPVPALVAAARTRFAAWRPSGPAPSVPAPSVPAPNAAATGPVVYYRDPDGKPV
YSLAPMMTADGREFRPVRASEDVRFDLPDDVPGPDTAGAEAAGHRPDSGTRAILYYRNPMGLPDTSPVPKKDSMGMDYIP
VYADAEAGGPVVTVPAGRIQRTGVRIATAERRVVAQPVRVPGTLALDERRVTVVATRSDAYVDRVESVTTGDRVRRGQPL
VHVYSPEINAAAAQLIANPGFDGARRRLQNLNVSADVIDAMERTRTVPMAITWSSPRDGIVLQRNAVEGMKAAAGDTLFR
IADIAVLWVLADVPERDLAGIRVGQVATVRPRSAPGRTVTGRVAVIYPQVNPETRATRVRIELPNPDGTLLPDMYADVAI
ATGSAEPVVAVPDDAVLDTGTRQVVLLERGEGRFEPRAVTLGARGEGFTEIRAGLAAGDRVVTAANFLIDAESNLKAALQ
SLAPPRDDRQAARAGDAP
>Mature_497_residues
SRTAWFAGALAALAAGGIGYGAGHGGDPVPALVAAARTRFAAWRPSGPAPSVPAPSVPAPNAAATGPVVYYRDPDGKPVY
SLAPMMTADGREFRPVRASEDVRFDLPDDVPGPDTAGAEAAGHRPDSGTRAILYYRNPMGLPDTSPVPKKDSMGMDYIPV
YADAEAGGPVVTVPAGRIQRTGVRIATAERRVVAQPVRVPGTLALDERRVTVVATRSDAYVDRVESVTTGDRVRRGQPLV
HVYSPEINAAAAQLIANPGFDGARRRLQNLNVSADVIDAMERTRTVPMAITWSSPRDGIVLQRNAVEGMKAAAGDTLFRI
ADIAVLWVLADVPERDLAGIRVGQVATVRPRSAPGRTVTGRVAVIYPQVNPETRATRVRIELPNPDGTLLPDMYADVAIA
TGSAEPVVAVPDDAVLDTGTRQVVLLERGEGRFEPRAVTLGARGEGFTEIRAGLAAGDRVVTAANFLIDAESNLKAALQS
LAPPRDDRQAARAGDAP

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=375, Percent_Identity=29.6, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081796, Length=178, Percent_Identity=32.5842696629214, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52431; Mature: 52300

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTAWFAGALAALAAGGIGYGAGHGGDPVPALVAAARTRFAAWRPSGPAPSVPAPSVPA
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCC
PNAAATGPVVYYRDPDGKPVYSLAPMMTADGREFRPVRASEDVRFDLPDDVPGPDTAGAE
CCCCCCCCEEEEECCCCCEEEEECCEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
AAGHRPDSGTRAILYYRNPMGLPDTSPVPKKDSMGMDYIPVYADAEAGGPVVTVPAGRIQ
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCEE
RTGVRIATAERRVVAQPVRVPGTLALDERRVTVVATRSDAYVDRVESVTTGDRVRRGQPL
ECCEEEEECCCHHEECCCCCCCEEEECCCEEEEEEECCCHHHHHHHHCCCCCHHHCCCCE
VHVYSPEINAAAAQLIANPGFDGARRRLQNLNVSADVIDAMERTRTVPMAITWSSPRDGI
EEEECCCCCHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCE
VLQRNAVEGMKAAAGDTLFRIADIAVLWVLADVPERDLAGIRVGQVATVRPRSAPGRTVT
EEECCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEEECCCCCCCCEEE
GRVAVIYPQVNPETRATRVRIELPNPDGTLLPDMYADVAIATGSAEPVVAVPDDAVLDTG
CEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHCCEEEECCCCCCEEECCCCCEECCC
TRQVVLLERGEGRFEPRAVTLGARGEGFTEIRAGLAAGDRVVTAANFLIDAESNLKAALQ
CCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHH
SLAPPRDDRQAARAGDAP
HHCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
SRTAWFAGALAALAAGGIGYGAGHGGDPVPALVAAARTRFAAWRPSGPAPSVPAPSVPA
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCC
PNAAATGPVVYYRDPDGKPVYSLAPMMTADGREFRPVRASEDVRFDLPDDVPGPDTAGAE
CCCCCCCCEEEEECCCCCEEEEECCEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
AAGHRPDSGTRAILYYRNPMGLPDTSPVPKKDSMGMDYIPVYADAEAGGPVVTVPAGRIQ
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCEE
RTGVRIATAERRVVAQPVRVPGTLALDERRVTVVATRSDAYVDRVESVTTGDRVRRGQPL
ECCEEEEECCCHHEECCCCCCCEEEECCCEEEEEEECCCHHHHHHHHCCCCCHHHCCCCE
VHVYSPEINAAAAQLIANPGFDGARRRLQNLNVSADVIDAMERTRTVPMAITWSSPRDGI
EEEECCCCCHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCE
VLQRNAVEGMKAAAGDTLFRIADIAVLWVLADVPERDLAGIRVGQVATVRPRSAPGRTVT
EEECCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEEECCCCCCCCEEE
GRVAVIYPQVNPETRATRVRIELPNPDGTLLPDMYADVAIATGSAEPVVAVPDDAVLDTG
CEEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHCCEEEECCCCCCEEECCCCCEECCC
TRQVVLLERGEGRFEPRAVTLGARGEGFTEIRAGLAAGDRVVTAANFLIDAESNLKAALQ
CCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHH
SLAPPRDDRQAARAGDAP
HHCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]