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The map label for this gene is cobS [H]

Identifier: 170750097

GI number: 170750097

Start: 3935942

End: 3936925

Strand: Direct

Name: cobS [H]

Synonym: Mrad2831_3698

Alternate gene names: 170750097

Gene position: 3935942-3936925 (Clockwise)

Preceding gene: 170750096

Following gene: 170750098

Centisome position: 64.76

GC content: 66.97

Gene sequence:

>984_bases
ATGCTCTCTGACGCTACGCCCGCCGCGCTGCCCGATCGCACCGTCTCCGTCCGCGATGTCTTCGGCATCGACCTCGACCT
CAAGGTCCCGGCCTTCGCCGAGCCCGAGGAGCACGTGCCGGATGTCGACCCGGACTACATCTTCGACCGGGAGACGACGC
TGGCGATCCTGGCCGGCTTCGCCCGCAACCGTCGCGTGATGGTCACCGGCTATCACGGCACCGGCAAGTCGACCCACATC
GAGCAGGTGGCCGCCCGGCTGAACTGGCCGTGCATCCGGATCAACCTCGACAGCCACGTCTCGCGCATCGACCTCGTCGG
CAAGGACGCCATCGTCCTGCAGGACGGCAAGCAGGTCACCGCCTTCCAGGACGGCATCCTGCCCTGGGCGCTGCAGAACA
ACGTCGCCCTCGTGTTCGACGAGTACGATGCCGGCCGCCCGGACGTGATGTTCGTGATCCAGCGCGTGCTGGAACTCTCG
GGCCGGCTGACGCTGCTCGATCAGAAGCGCGTGATCCGCCCGCACCCGGCCTTCCGGCTGTTCGCCACCGCCAACACGGT
GGGCCTGGGCGACACGTCGGGCCTCTATCACGGCACGCAGCAGATCAACCAGGGCCAGATGGACCGCTGGTCGATCGTCA
CCACGCTCAACTACCTGCCGCACGACCGCGAGGTCGACATCGTGCTCTCGAAGGCGACCCATTACCGGGGCGACCAGGGC
CGCGACATCGTCAACCGGATGGTGCGCGTGGCGGACCTGACCCGCAACGCCTTCATGAACGGCGACCTCTCGACCGTCAT
GAGCCCGCGCACGGTGATCACCTGGGCCGAGAACGCCGACATCTTCAAGGATATCGGCTTCGCGTTCCGGGTGACCTTCC
TCAACAAGTGCGACGAGCTGGAGCGGACGCTGGTGGCCGAGTTCTACCAGCGCGCCTTCGGCAAGGAGCTGCCCGAGAGC
GCGGTGAACGTCGCGCTGAGCTGA

Upstream 100 bases:

>100_bases
AAGGATGGCTCCGCCCCGCCGCGGAGGCCCGGCTCGACGTTCTTCCGCGCGGATGCTTCACTGTTTGGGAGTGGAGCGCC
CGCGCCTCACGAGGTTCCGA

Downstream 100 bases:

>100_bases
CCCGCATGGAGGACGCGATGGCGCATCCGGCCCCCGCGCGCGAGGACGCCCCGGCGACTGCGCATGCCCGGGGACGGACG
CGCCACGCGGACGATCTCTA

Product: cobalt chelatase, pCobS small subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLSDATPAALPDRTVSVRDVFGIDLDLKVPAFAEPEEHVPDVDPDYIFDRETTLAILAGFARNRRVMVTGYHGTGKSTHI
EQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLQDGKQVTAFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELS
GRLTLLDQKRVIRPHPAFRLFATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKATHYRGDQG
RDIVNRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFKDIGFAFRVTFLNKCDELERTLVAEFYQRAFGKELPES
AVNVALS

Sequences:

>Translated_327_residues
MLSDATPAALPDRTVSVRDVFGIDLDLKVPAFAEPEEHVPDVDPDYIFDRETTLAILAGFARNRRVMVTGYHGTGKSTHI
EQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLQDGKQVTAFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELS
GRLTLLDQKRVIRPHPAFRLFATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKATHYRGDQG
RDIVNRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFKDIGFAFRVTFLNKCDELERTLVAEFYQRAFGKELPES
AVNVALS
>Mature_327_residues
MLSDATPAALPDRTVSVRDVFGIDLDLKVPAFAEPEEHVPDVDPDYIFDRETTLAILAGFARNRRVMVTGYHGTGKSTHI
EQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLQDGKQVTAFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELS
GRLTLLDQKRVIRPHPAFRLFATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKATHYRGDQG
RDIVNRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFKDIGFAFRVTFLNKCDELERTLVAEFYQRAFGKELPES
AVNVALS

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=242, Percent_Identity=23.5537190082645, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076562, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076560, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36669; Mature: 36669

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDATPAALPDRTVSVRDVFGIDLDLKVPAFAEPEEHVPDVDPDYIFDRETTLAILAGF
CCCCCCCCCCCCCCEEEEEEEECEEEECCCCCCCCHHCCCCCCCCEEECCCHHHHHHHHH
ARNRRVMVTGYHGTGKSTHIEQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLQDGKQVT
HCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCEEE
AFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELSGRLTLLDQKRVIRPHPAFRL
EHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEE
FATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKATHYRGDQG
EEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEHHCCCCCCCEEEEEECCCCCCCCCC
RDIVNRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFKDIGFAFRVTFLNKCDEL
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCHHHHHCCHHEEHHHHHHHHHH
ERTLVAEFYQRAFGKELPESAVNVALS
HHHHHHHHHHHHHCCCCCHHHHHEECC
>Mature Secondary Structure
MLSDATPAALPDRTVSVRDVFGIDLDLKVPAFAEPEEHVPDVDPDYIFDRETTLAILAGF
CCCCCCCCCCCCCCEEEEEEEECEEEECCCCCCCCHHCCCCCCCCEEECCCHHHHHHHHH
ARNRRVMVTGYHGTGKSTHIEQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLQDGKQVT
HCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCEEE
AFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELSGRLTLLDQKRVIRPHPAFRL
EHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEE
FATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKATHYRGDQG
EEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEHHCCCCCCCEEEEEECCCCCCCCCC
RDIVNRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFKDIGFAFRVTFLNKCDEL
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCHHHHHCCHHEEHHHHHHHHHH
ERTLVAEFYQRAFGKELPESAVNVALS
HHHHHHHHHHHHHCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]