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The map label for this gene is lig [H]

Identifier: 170750091

GI number: 170750091

Start: 3931140

End: 3932195

Strand: Reverse

Name: lig [H]

Synonym: Mrad2831_3692

Alternate gene names: 170750091

Gene position: 3932195-3931140 (Counterclockwise)

Preceding gene: 170750094

Following gene: 170750090

Centisome position: 64.7

GC content: 72.63

Gene sequence:

>1056_bases
ATGCCGATACGCGCCAGCGATCTCCTCACCCTGACCCGCGAGGGTCTCTACTGCCCCCTCGGGCGCTTCCACGTCGATCC
GACCTGGCCGGTGGAGCGCGCGCTCATCACCCACGGGCACGCCGACCACGCCCGCGCGGGCCACGGCCACGTGCTGGCGA
CGCCCGAGACCCTGCGGATCATGGCGGTGCGCTACGGCGCGGATTTCTGCCGCCAGCGGCAGGAGGCGCCGCTCGGGGCG
GCGCTCCGCGTCGGCGACGTCACCGTGCGCTTCGCCCCGGCCGGCCACGTGCTCGGCTCGGCGCAGATCGCCATCGAGCG
GGACGGCGTCCGCGTCGTGGTCTCGGGCGACTACAAGCGCGCGCCGGACCCGACCTGCCTGCCGTTCGAGGTCGTGCCCT
GCGACGTGTTCATCACCGAGGCGACCTTCGGCCTGCCGGTCTTCACCCACCCCGACACGCGGGGCGAGGTCCGCAAGCTC
CTCGAATCGGTCAGACTGTTCCCGGAGCGCGCCCACATCGTGGGGGCCTACGCGCTCGGCAAGGCGCAGCGGGTGATGGC
GCTCCTGCGCGAGGAGGGCTGGGACCGCCCGATCCACCTGCACGGCGCCATGGAGAAGCTCACCACGCTGTACAAGGAGG
AAGGCGTGCCGCTGGGCGACACGCCCAAGGTCGTGGCCGCCGAGCGCAAGGACCTGCACGGGGCGATCGTTCTCTGCCCG
CCCTCGTCGATCCAGGACCTGTGGTCCCGCAAATTCCCCGACCCGGTGACCTGCTTCGCCTCGGGCTGGATGCGGGTGCG
CGCCCGCGCCCGCCAGAAGGGCGTCGAGCTGCCGCTGGTGATCTCCGACCATTCCGACTGGCCTGACCTGTGCCGCACCA
TCCGCGACACCGGCGCCGGGGAGGTCTGGGTGACGCACGGGCAGGAGGACGCGCTGGTCCACTGGTGCGGGACGCAGGGC
ATCCGGGCGAAGCCGCTCCACCTGCTCGGCTACGGCGATGACGGCGAGGTCGAGGGGACCTCGGAGGCGAGCTCTGAGGC
GGAGGCGGCCGCGTGA

Upstream 100 bases:

>100_bases
AGGAGGTCGCCGGAACTGAGCTGCGAGGCCATGCGTCTGCCGGTTCGGGGGCGCCTATATACCGGGGCCACCGGCGGACT
CCACCGGCAGCACGGACCCG

Downstream 100 bases:

>100_bases
ACGAGTTCGCCCATCTCCTCGACCGCCTCGCCTACGAGCCGCGCCGCAACGCGAAGCTGCGCATGCTCCAGGACTACTTC
GCGCGCACGCCCGACCCCGA

Product: putative mRNA 3-end processing factor

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPIRASDLLTLTREGLYCPLGRFHVDPTWPVERALITHGHADHARAGHGHVLATPETLRIMAVRYGADFCRQRQEAPLGA
ALRVGDVTVRFAPAGHVLGSAQIAIERDGVRVVVSGDYKRAPDPTCLPFEVVPCDVFITEATFGLPVFTHPDTRGEVRKL
LESVRLFPERAHIVGAYALGKAQRVMALLREEGWDRPIHLHGAMEKLTTLYKEEGVPLGDTPKVVAAERKDLHGAIVLCP
PSSIQDLWSRKFPDPVTCFASGWMRVRARARQKGVELPLVISDHSDWPDLCRTIRDTGAGEVWVTHGQEDALVHWCGTQG
IRAKPLHLLGYGDDGEVEGTSEASSEAEAAA

Sequences:

>Translated_351_residues
MPIRASDLLTLTREGLYCPLGRFHVDPTWPVERALITHGHADHARAGHGHVLATPETLRIMAVRYGADFCRQRQEAPLGA
ALRVGDVTVRFAPAGHVLGSAQIAIERDGVRVVVSGDYKRAPDPTCLPFEVVPCDVFITEATFGLPVFTHPDTRGEVRKL
LESVRLFPERAHIVGAYALGKAQRVMALLREEGWDRPIHLHGAMEKLTTLYKEEGVPLGDTPKVVAAERKDLHGAIVLCP
PSSIQDLWSRKFPDPVTCFASGWMRVRARARQKGVELPLVISDHSDWPDLCRTIRDTGAGEVWVTHGQEDALVHWCGTQG
IRAKPLHLLGYGDDGEVEGTSEASSEAEAAA
>Mature_350_residues
PIRASDLLTLTREGLYCPLGRFHVDPTWPVERALITHGHADHARAGHGHVLATPETLRIMAVRYGADFCRQRQEAPLGAA
LRVGDVTVRFAPAGHVLGSAQIAIERDGVRVVVSGDYKRAPDPTCLPFEVVPCDVFITEATFGLPVFTHPDTRGEVRKLL
ESVRLFPERAHIVGAYALGKAQRVMALLREEGWDRPIHLHGAMEKLTTLYKEEGVPLGDTPKVVAAERKDLHGAIVLCPP
SSIQDLWSRKFPDPVTCFASGWMRVRARARQKGVELPLVISDHSDWPDLCRTIRDTGAGEVWVTHGQEDALVHWCGTQGI
RAKPLHLLGYGDDGEVEGTSEASSEAEAAA

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 38490; Mature: 38359

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRASDLLTLTREGLYCPLGRFHVDPTWPVERALITHGHADHARAGHGHVLATPETLRI
CCCCCHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCEEE
MAVRYGADFCRQRQEAPLGAALRVGDVTVRFAPAGHVLGSAQIAIERDGVRVVVSGDYKR
EEEECCHHHHHHHHCCCCCCEEEECCEEEEEECCCCEECCEEEEEEECCEEEEEECCCCC
APDPTCLPFEVVPCDVFITEATFGLPVFTHPDTRGEVRKLLESVRLFPERAHIVGAYALG
CCCCCCCEEEEEEEEEEEEEEECCCEEEECCCCHHHHHHHHHHHHCCCCHHHEEEHHHHH
KAQRVMALLREEGWDRPIHLHGAMEKLTTLYKEEGVPLGDTPKVVAAERKDLHGAIVLCP
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEC
PSSIQDLWSRKFPDPVTCFASGWMRVRARARQKGVELPLVISDHSDWPDLCRTIRDTGAG
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCC
EVWVTHGQEDALVHWCGTQGIRAKPLHLLGYGDDGEVEGTSEASSEAEAAA
EEEEEECCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
PIRASDLLTLTREGLYCPLGRFHVDPTWPVERALITHGHADHARAGHGHVLATPETLRI
CCCCHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCEEE
MAVRYGADFCRQRQEAPLGAALRVGDVTVRFAPAGHVLGSAQIAIERDGVRVVVSGDYKR
EEEECCHHHHHHHHCCCCCCEEEECCEEEEEECCCCEECCEEEEEEECCEEEEEECCCCC
APDPTCLPFEVVPCDVFITEATFGLPVFTHPDTRGEVRKLLESVRLFPERAHIVGAYALG
CCCCCCCEEEEEEEEEEEEEEECCCEEEECCCCHHHHHHHHHHHHCCCCHHHEEEHHHHH
KAQRVMALLREEGWDRPIHLHGAMEKLTTLYKEEGVPLGDTPKVVAAERKDLHGAIVLCP
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEC
PSSIQDLWSRKFPDPVTCFASGWMRVRARARQKGVELPLVISDHSDWPDLCRTIRDTGAG
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCC
EVWVTHGQEDALVHWCGTQGIRAKPLHLLGYGDDGEVEGTSEASSEAEAAA
EEEEEECCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA