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The map label for this gene is yfnA [H]

Identifier: 170750076

GI number: 170750076

Start: 3910743

End: 3912191

Strand: Direct

Name: yfnA [H]

Synonym: Mrad2831_3677

Alternate gene names: 170750076

Gene position: 3910743-3912191 (Clockwise)

Preceding gene: 170750075

Following gene: 170750078

Centisome position: 64.34

GC content: 67.43

Gene sequence:

>1449_bases
ATGGATTCGTCGGGCCTGATGGGGCGGAAGTCGGTCGACGACATCGTCGAGAGCGGCGAGGGCGAGCAGCAACTCTCGAA
GTCGCTCGGCGCCCTCTCGATCACCGCGATGGGTATCGGGGCGATCATCGGCGCCGGCATCTTCGTCCTCACCGGCACCG
CCGCGGCCCAGTATGCCGGGCCGGGGATCATGCTGTCCTTCGTGCTCGGCGGCATCGCCTGCGCCTTCGTCGGCCTCTGC
TACTCCGAGATGGCCGCGCTGATCCCGGTCGCCGGCTCGAGCTACACCTACACCTACGCGACGCTCGGCGAGTTCTTCGC
GTGGCTGATCGGCTGGGACCTGATCCTCGAATACGCCATGGGCGCCGCCACCGTGGCGGTCGGCTGGTCGGGCTACATGA
CCAGCATCCTCAAGAGTGTCGGCATCGTGATCCCCGCGCAGTTCGCCAACGCGCCAGGCACGCCGATCGAGGGCGGCGGG
ACCGCCCTGTTCAACCTGCCGGCCGTGCTGATCGTGGCGCTGATCACGATCCTGCTGATGCGGGGCACGAAGGAATCGGC
GCGCTTCAACAACGTCATGGTCGCGGTGAAACTCACCGTCGTGATCGCCTTCATCGTTCTCGGCTGGAGCCATGTGAACG
CCGCGAACTGGAGCCCGCTGATCCCCGAGAACGACGGGACCTTCGGACATTTCGGCACCAGTGGCGTCCTGCGCGGCGCG
GGCGTGGTGTTCTTCGCGTTCATCGGCTTCGACGCGGTCTCGACCGCCGCCCAGGAGGCGCGCAGACCCCAGAAGGACAT
GCCGATCGGCATCCTGGGCTCGCTGGCGGTCTGCACGATCCTGTACGTGCTCGTCGCCGCCGTGCTCACCGGGCTCGTGC
CCTACAAGGAGCTGAACGTCCCGGACCCGATCGCCAAGGGCGTCGACGTGATCGGCATCGGCTGGTTCGCCCTCCTGATC
AAGCTCGGGGCGCTGACCGGGCTGACCACGGTGATCCTCGTCCTGCTCTACGGCCAGAGCCGGATCTTCTTCACCATGGC
CCAGGACGGCCTGCTGCCGAAGATGTTCTCCCACGTCCACCCGACCTACCAGACGCCGTATCGCAGCCAGGCGCTCATCG
GGGCCGCGGTCGCCGTGGTGGCGGCCCTGGTGCCGATCCACATCCTCGGCGAGATGGTCAGCATCGGCACGCTCGCCGCC
TTCATCCTCGTCTGCGGCTCAGTGCTCTACCTGCGGCGCGCCGAGCGCCACATGAAGCGGCCGTTCCGGGCGCCCGCCGT
GCCGGTCGTGCCGATCCTGGGCATCCTGTCCTGCCTGCTCCTGATGATCGGCCTGCCCCTCGACACGTGGCTGCGGCTGG
TGATCTGGATGGCGATCGGCCTCGTCGTGTACTTCTTCTACGGCCGCAAGCACTCTGTCCTGCGCCGCAAGGAGGGGAAT
CTGGCCTAG

Upstream 100 bases:

>100_bases
GGTCGATTCGCCGCTACAACTCTGGAAGCGCGGCAGAAACGGCGCCGCCTCCGGCCGTGTCGACGCGCGCTGAATCTCCC
CGACTTGGAAGGATGGTGCC

Downstream 100 bases:

>100_bases
CGCCGCCTCACACGGTGAGGCTCGCGCCGCGCCGCAGGTGCTCGTCGAGGCGCGGCATGATCTCGACGAAGTTGCAGGGC
CGGTGCCGGTAGTCGAGCTG

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MDSSGLMGRKSVDDIVESGEGEQQLSKSLGALSITAMGIGAIIGAGIFVLTGTAAAQYAGPGIMLSFVLGGIACAFVGLC
YSEMAALIPVAGSSYTYTYATLGEFFAWLIGWDLILEYAMGAATVAVGWSGYMTSILKSVGIVIPAQFANAPGTPIEGGG
TALFNLPAVLIVALITILLMRGTKESARFNNVMVAVKLTVVIAFIVLGWSHVNAANWSPLIPENDGTFGHFGTSGVLRGA
GVVFFAFIGFDAVSTAAQEARRPQKDMPIGILGSLAVCTILYVLVAAVLTGLVPYKELNVPDPIAKGVDVIGIGWFALLI
KLGALTGLTTVILVLLYGQSRIFFTMAQDGLLPKMFSHVHPTYQTPYRSQALIGAAVAVVAALVPIHILGEMVSIGTLAA
FILVCGSVLYLRRAERHMKRPFRAPAVPVVPILGILSCLLLMIGLPLDTWLRLVIWMAIGLVVYFFYGRKHSVLRRKEGN
LA

Sequences:

>Translated_482_residues
MDSSGLMGRKSVDDIVESGEGEQQLSKSLGALSITAMGIGAIIGAGIFVLTGTAAAQYAGPGIMLSFVLGGIACAFVGLC
YSEMAALIPVAGSSYTYTYATLGEFFAWLIGWDLILEYAMGAATVAVGWSGYMTSILKSVGIVIPAQFANAPGTPIEGGG
TALFNLPAVLIVALITILLMRGTKESARFNNVMVAVKLTVVIAFIVLGWSHVNAANWSPLIPENDGTFGHFGTSGVLRGA
GVVFFAFIGFDAVSTAAQEARRPQKDMPIGILGSLAVCTILYVLVAAVLTGLVPYKELNVPDPIAKGVDVIGIGWFALLI
KLGALTGLTTVILVLLYGQSRIFFTMAQDGLLPKMFSHVHPTYQTPYRSQALIGAAVAVVAALVPIHILGEMVSIGTLAA
FILVCGSVLYLRRAERHMKRPFRAPAVPVVPILGILSCLLLMIGLPLDTWLRLVIWMAIGLVVYFFYGRKHSVLRRKEGN
LA
>Mature_482_residues
MDSSGLMGRKSVDDIVESGEGEQQLSKSLGALSITAMGIGAIIGAGIFVLTGTAAAQYAGPGIMLSFVLGGIACAFVGLC
YSEMAALIPVAGSSYTYTYATLGEFFAWLIGWDLILEYAMGAATVAVGWSGYMTSILKSVGIVIPAQFANAPGTPIEGGG
TALFNLPAVLIVALITILLMRGTKESARFNNVMVAVKLTVVIAFIVLGWSHVNAANWSPLIPENDGTFGHFGTSGVLRGA
GVVFFAFIGFDAVSTAAQEARRPQKDMPIGILGSLAVCTILYVLVAAVLTGLVPYKELNVPDPIAKGVDVIGIGWFALLI
KLGALTGLTTVILVLLYGQSRIFFTMAQDGLLPKMFSHVHPTYQTPYRSQALIGAAVAVVAALVPIHILGEMVSIGTLAA
FILVCGSVLYLRRAERHMKRPFRAPAVPVVPILGILSCLLLMIGLPLDTWLRLVIWMAIGLVVYFFYGRKHSVLRRKEGN
LA

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=415, Percent_Identity=36.3855421686747, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI258614003, Length=415, Percent_Identity=36.3855421686747, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI258645169, Length=415, Percent_Identity=36.6265060240964, Blast_Score=233, Evalue=4e-61,
Organism=Homo sapiens, GI4507047, Length=419, Percent_Identity=35.0835322195704, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI181337167, Length=414, Percent_Identity=34.7826086956522, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI110347453, Length=400, Percent_Identity=34.25, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI114326544, Length=423, Percent_Identity=33.806146572104, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI114326550, Length=423, Percent_Identity=33.806146572104, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI115648063, Length=494, Percent_Identity=23.6842105263158, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI115648022, Length=494, Percent_Identity=23.6842105263158, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI186910308, Length=487, Percent_Identity=24.8459958932238, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI186910306, Length=487, Percent_Identity=24.8459958932238, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI186910304, Length=487, Percent_Identity=24.8459958932238, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI71979932, Length=477, Percent_Identity=24.3186582809224, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI187423910, Length=488, Percent_Identity=22.7459016393443, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI7657591, Length=488, Percent_Identity=22.7459016393443, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI33286428, Length=423, Percent_Identity=24.5862884160757, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI9790235, Length=322, Percent_Identity=23.9130434782609, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082250, Length=471, Percent_Identity=27.3885350318471, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87081708, Length=473, Percent_Identity=23.8900634249471, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788480, Length=470, Percent_Identity=26.1702127659574, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081869, Length=479, Percent_Identity=21.5031315240083, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786302, Length=437, Percent_Identity=24.7139588100687, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87082023, Length=464, Percent_Identity=23.2758620689655, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87081915, Length=428, Percent_Identity=26.1682242990654, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790653, Length=502, Percent_Identity=24.5019920318725, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789017, Length=424, Percent_Identity=25, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786694, Length=474, Percent_Identity=25.3164556962025, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786789, Length=488, Percent_Identity=24.7950819672131, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367353, Length=483, Percent_Identity=24.223602484472, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786602, Length=483, Percent_Identity=21.9461697722567, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI48994972, Length=485, Percent_Identity=22.680412371134, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790575, Length=335, Percent_Identity=22.6865671641791, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=399, Percent_Identity=36.5914786967419, Blast_Score=249, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17531343, Length=393, Percent_Identity=35.3689567430025, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17533459, Length=399, Percent_Identity=32.0802005012531, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17568033, Length=486, Percent_Identity=24.0740740740741, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540018, Length=232, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566699, Length=316, Percent_Identity=23.1012658227848, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982612, Length=456, Percent_Identity=22.5877192982456, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982608, Length=456, Percent_Identity=22.5877192982456, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=37.6777251184834, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=37.6777251184834, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24667468, Length=429, Percent_Identity=37.0629370629371, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24668806, Length=435, Percent_Identity=34.9425287356322, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI21356285, Length=435, Percent_Identity=34.9425287356322, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24668802, Length=435, Percent_Identity=34.9425287356322, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI281366235, Length=417, Percent_Identity=33.5731414868106, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI116007820, Length=417, Percent_Identity=33.5731414868106, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI161077963, Length=414, Percent_Identity=35.2657004830918, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI116007818, Length=414, Percent_Identity=33.8164251207729, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI85725152, Length=414, Percent_Identity=33.8164251207729, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI21357367, Length=436, Percent_Identity=24.5412844036697, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI221331183, Length=448, Percent_Identity=23.4375, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17647653, Length=448, Percent_Identity=23.4375, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24664379, Length=448, Percent_Identity=23.4375, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550968, Length=475, Percent_Identity=24, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921172, Length=475, Percent_Identity=24, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24651635, Length=449, Percent_Identity=23.6080178173719, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24651633, Length=449, Percent_Identity=23.6080178173719, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50984; Mature: 50984

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSGLMGRKSVDDIVESGEGEQQLSKSLGALSITAMGIGAIIGAGIFVLTGTAAAQYAG
CCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
PGIMLSFVLGGIACAFVGLCYSEMAALIPVAGSSYTYTYATLGEFFAWLIGWDLILEYAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
GAATVAVGWSGYMTSILKSVGIVIPAQFANAPGTPIEGGGTALFNLPAVLIVALITILLM
HHHHHHHCHHHHHHHHHHHCCCEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RGTKESARFNNVMVAVKLTVVIAFIVLGWSHVNAANWSPLIPENDGTFGHFGTSGVLRGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
GVVFFAFIGFDAVSTAAQEARRPQKDMPIGILGSLAVCTILYVLVAAVLTGLVPYKELNV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCC
PDPIAKGVDVIGIGWFALLIKLGALTGLTTVILVLLYGQSRIFFTMAQDGLLPKMFSHVH
CCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCC
PTYQTPYRSQALIGAAVAVVAALVPIHILGEMVSIGTLAAFILVCGSVLYLRRAERHMKR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFRAPAVPVVPILGILSCLLLMIGLPLDTWLRLVIWMAIGLVVYFFYGRKHSVLRRKEGN
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
LA
CC
>Mature Secondary Structure
MDSSGLMGRKSVDDIVESGEGEQQLSKSLGALSITAMGIGAIIGAGIFVLTGTAAAQYAG
CCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
PGIMLSFVLGGIACAFVGLCYSEMAALIPVAGSSYTYTYATLGEFFAWLIGWDLILEYAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
GAATVAVGWSGYMTSILKSVGIVIPAQFANAPGTPIEGGGTALFNLPAVLIVALITILLM
HHHHHHHCHHHHHHHHHHHCCCEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RGTKESARFNNVMVAVKLTVVIAFIVLGWSHVNAANWSPLIPENDGTFGHFGTSGVLRGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
GVVFFAFIGFDAVSTAAQEARRPQKDMPIGILGSLAVCTILYVLVAAVLTGLVPYKELNV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCC
PDPIAKGVDVIGIGWFALLIKLGALTGLTTVILVLLYGQSRIFFTMAQDGLLPKMFSHVH
CCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCC
PTYQTPYRSQALIGAAVAVVAALVPIHILGEMVSIGTLAAFILVCGSVLYLRRAERHMKR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFRAPAVPVVPILGILSCLLLMIGLPLDTWLRLVIWMAIGLVVYFFYGRKHSVLRRKEGN
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
LA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]