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The map label for this gene is yxnA [H]

Identifier: 170749954

GI number: 170749954

Start: 3773568

End: 3774578

Strand: Direct

Name: yxnA [H]

Synonym: Mrad2831_3554

Alternate gene names: 170749954

Gene position: 3773568-3774578 (Clockwise)

Preceding gene: 170749952

Following gene: 170749959

Centisome position: 62.09

GC content: 73.29

Gene sequence:

>1011_bases
ATGGTCACGGGTGCGAGCGCCGGCGTCGGCCGCGCTGTCGCCCACGAGTTCGCCCGGCACGGGTGGAACGTGGGGCTGAT
CGCGCGCGGCGAGGCGGGGCTGCGGGGCACGATCCGCGACGTCGAGCGGGCCGGAGGCCGGGCCCTGGCCTTCGCGGCCG
ACGTCGCCGACGCGGAGGCTGTCGCCCAGGCGGCCGACGAGCTGGCCGAGGCGTTCGGCGGCATCGACGTCTGGGTCAAC
AACGCGATGGTGACGGTCTACGCGCCCGTTCAGGAGACGAGCCCGGAGGAGTTCCACCGCGCCACCGCGGTGACCTATCT
CGGCCAGGTGCACGGCACGCTGGCGGCGCTCCGCCACATGGTGCCGCGCGACCGGGGCACGATCGTGCATGTCGGCTCGG
CGCTCGCCTACCGGTCGATCCCGCTCCAGGCGAGCTACTGCGCCGCGAAGGCCGCCGTGCGGGGCTTCGTCGATTCCCTG
CGCAGCGAGCTGCTGCACGACCGCAGCCGGGTACGCCTGACGATGGTGCAGCTTCCGGCCGTGAACACGCCGCAGTTCGA
CTGGGCCCGCTCGCGGCTGCCGCGCAAGCTTGAGCCGGTGCCGCCGATCTACCAGCCCGAGGCCATCGCCCGGCACGTCT
TCCGAGCGGCACACGACGCGCCGCGGGAAATGTGGATCGGGGCCTCGGCCTGGAAGGCGATCATCGGGAACATGCTGATT
CCGGGCTGGATCGACGGCTACCTCGCCCGGCACGGCTATCGCGGGGAGATGACCGGCGTGCAGGCACAGAAGAACCGCCC
CGACAACCTCTACGACCCGGTGGACACCGATCCCGGCGCCCACGGCCGCTTCGACGCCCGTGCGACCGGCGACGTCGCGG
CGGTCGATCCCCGCTGGCTCAAGTTCGGGCTCGCGGCCGCGCTCGGTGTCGTCGCCGGCACGATGCTGTTCGCCACCGAG
GCGCACGGACGTGCGGATGCCCGCGCCGACCGCCGGCTGGGCCGACGCTAG

Upstream 100 bases:

>100_bases
ATCCCGTGACCGCGGAAAGAACGGCCGCCTCGGGCGTTGGCGCTGGACTTCACGCGCAGCTGGGAACCCGATGTCGAGCC
GGAACGGACGCAGCACGGTC

Downstream 100 bases:

>100_bases
GACTCGGGCCTTCGCGGGGCCCGTCGCGCCGCCGCGAAGGCCTCGCCCACGGGGCCGCGTCGCGCCCCCTGGGCGCGGGG
GCCTCTGGGAGGATCCGGTG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MVTGASAGVGRAVAHEFARHGWNVGLIARGEAGLRGTIRDVERAGGRALAFAADVADAEAVAQAADELAEAFGGIDVWVN
NAMVTVYAPVQETSPEEFHRATAVTYLGQVHGTLAALRHMVPRDRGTIVHVGSALAYRSIPLQASYCAAKAAVRGFVDSL
RSELLHDRSRVRLTMVQLPAVNTPQFDWARSRLPRKLEPVPPIYQPEAIARHVFRAAHDAPREMWIGASAWKAIIGNMLI
PGWIDGYLARHGYRGEMTGVQAQKNRPDNLYDPVDTDPGAHGRFDARATGDVAAVDPRWLKFGLAAALGVVAGTMLFATE
AHGRADARADRRLGRR

Sequences:

>Translated_336_residues
MVTGASAGVGRAVAHEFARHGWNVGLIARGEAGLRGTIRDVERAGGRALAFAADVADAEAVAQAADELAEAFGGIDVWVN
NAMVTVYAPVQETSPEEFHRATAVTYLGQVHGTLAALRHMVPRDRGTIVHVGSALAYRSIPLQASYCAAKAAVRGFVDSL
RSELLHDRSRVRLTMVQLPAVNTPQFDWARSRLPRKLEPVPPIYQPEAIARHVFRAAHDAPREMWIGASAWKAIIGNMLI
PGWIDGYLARHGYRGEMTGVQAQKNRPDNLYDPVDTDPGAHGRFDARATGDVAAVDPRWLKFGLAAALGVVAGTMLFATE
AHGRADARADRRLGRR
>Mature_336_residues
MVTGASAGVGRAVAHEFARHGWNVGLIARGEAGLRGTIRDVERAGGRALAFAADVADAEAVAQAADELAEAFGGIDVWVN
NAMVTVYAPVQETSPEEFHRATAVTYLGQVHGTLAALRHMVPRDRGTIVHVGSALAYRSIPLQASYCAAKAAVRGFVDSL
RSELLHDRSRVRLTMVQLPAVNTPQFDWARSRLPRKLEPVPPIYQPEAIARHVFRAAHDAPREMWIGASAWKAIIGNMLI
PGWIDGYLARHGYRGEMTGVQAQKNRPDNLYDPVDTDPGAHGRFDARATGDVAAVDPRWLKFGLAAALGVVAGTMLFATE
AHGRADARADRRLGRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=167, Percent_Identity=34.7305389221557, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI20149619, Length=183, Percent_Identity=28.9617486338798, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI31543615, Length=207, Percent_Identity=31.4009661835749, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4503817, Length=239, Percent_Identity=25.9414225941423, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI40254992, Length=202, Percent_Identity=30.6930693069307, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI210032110, Length=164, Percent_Identity=31.0975609756098, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI40807363, Length=217, Percent_Identity=25.8064516129032, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI142976729, Length=200, Percent_Identity=29, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI310128830, Length=255, Percent_Identity=25.8823529411765, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI310115468, Length=255, Percent_Identity=25.8823529411765, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI157739938, Length=277, Percent_Identity=24.187725631769, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI32455239, Length=243, Percent_Identity=26.7489711934156, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI5031765, Length=243, Percent_Identity=26.7489711934156, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI38348362, Length=179, Percent_Identity=31.8435754189944, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4557649, Length=199, Percent_Identity=28.1407035175879, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4504505, Length=259, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI38424085, Length=179, Percent_Identity=31.8435754189944, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=192, Percent_Identity=27.6041666666667, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=26.9076305220884, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786701, Length=258, Percent_Identity=27.1317829457364, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787335, Length=164, Percent_Identity=31.7073170731707, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082100, Length=202, Percent_Identity=30.6930693069307, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=194, Percent_Identity=29.8969072164948, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=228, Percent_Identity=28.0701754385965, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193203115, Length=228, Percent_Identity=28.0701754385965, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17567345, Length=164, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=215, Percent_Identity=26.5116279069767, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17508895, Length=248, Percent_Identity=25.8064516129032, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71997402, Length=167, Percent_Identity=29.940119760479, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=175, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=127, Percent_Identity=29.9212598425197, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=31.1557788944724, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356301, Length=260, Percent_Identity=28.0769230769231, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24640492, Length=203, Percent_Identity=25.615763546798, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=182, Percent_Identity=30.2197802197802, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281364892, Length=222, Percent_Identity=27.4774774774775, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581726, Length=201, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221510726, Length=201, Percent_Identity=29.3532338308458, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=165, Percent_Identity=32.1212121212121, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI23397609, Length=165, Percent_Identity=34.5454545454545, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24649181, Length=215, Percent_Identity=24.6511627906977, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355631, Length=177, Percent_Identity=26.5536723163842, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24644339, Length=174, Percent_Identity=28.1609195402299, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=169, Percent_Identity=31.9526627218935, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36301; Mature: 36301

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTGASAGVGRAVAHEFARHGWNVGLIARGEAGLRGTIRDVERAGGRALAFAADVADAEA
CCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHH
VAQAADELAEAFGGIDVWVNNAMVTVYAPVQETSPEEFHRATAVTYLGQVHGTLAALRHM
HHHHHHHHHHHHCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VPRDRGTIVHVGSALAYRSIPLQASYCAAKAAVRGFVDSLRSELLHDRSRVRLTMVQLPA
CCCCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEEECCC
VNTPQFDWARSRLPRKLEPVPPIYQPEAIARHVFRAAHDAPREMWIGASAWKAIIGNMLI
CCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHCCCCC
PGWIDGYLARHGYRGEMTGVQAQKNRPDNLYDPVDTDPGAHGRFDARATGDVAAVDPRWL
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHH
KFGLAAALGVVAGTMLFATEAHGRADARADRRLGRR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MVTGASAGVGRAVAHEFARHGWNVGLIARGEAGLRGTIRDVERAGGRALAFAADVADAEA
CCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHH
VAQAADELAEAFGGIDVWVNNAMVTVYAPVQETSPEEFHRATAVTYLGQVHGTLAALRHM
HHHHHHHHHHHHCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VPRDRGTIVHVGSALAYRSIPLQASYCAAKAAVRGFVDSLRSELLHDRSRVRLTMVQLPA
CCCCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEEECCC
VNTPQFDWARSRLPRKLEPVPPIYQPEAIARHVFRAAHDAPREMWIGASAWKAIIGNMLI
CCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHCCCCC
PGWIDGYLARHGYRGEMTGVQAQKNRPDNLYDPVDTDPGAHGRFDARATGDVAAVDPRWL
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHH
KFGLAAALGVVAGTMLFATEAHGRADARADRRLGRR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]