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The map label for this gene is yyaJ [H]

Identifier: 170749930

GI number: 170749930

Start: 3745278

End: 3746687

Strand: Direct

Name: yyaJ [H]

Synonym: Mrad2831_3530

Alternate gene names: 170749930

Gene position: 3745278-3746687 (Clockwise)

Preceding gene: 170749929

Following gene: 170749931

Centisome position: 61.62

GC content: 71.84

Gene sequence:

>1410_bases
ATGGCGACGCGTACGGCGGTCCGGGCTGCCGATGAAGGTCTCGATCCCGGCGCCATCCTGGCCCGTCTCGACCGGCTTCC
GGCGACGCCGACGGTCTGGCGCCTCGTGGTGCTGCTCGGGCTCGGCTTCTTCTTCGAGCTCTACGACCTGCTCTTCACCG
GCTACGTCGCGCCGGGCCTCGTCAAGGCCGGGATCCTGACGCCGACGACCCCGGGCCTGTTCGGTGCCAGCGGCGTCGCG
AGCTTCGTCGCCGCCCTGTTCACCGGCCTATTCATCGGCACCCTCGCCTGCGGCTGGCTCGCCGACCGGTTCGGCCGGCG
GGCGATCTTCACGTGGTCGCTCTTGTCCTACACCGCCGCCAACGTGGTGATGGCCTGCCAGAGCGACGCCTTCGGCCTCA
ATCTCTGGCGCCTGATCGCCGGGATCGGCCTCGGCCTGGAGATGGTGACGATCGGCAGCTACCTCTCCGAGCTGGTGCCG
AAGGCGATCCGCGGCCGGGCCTTCGCCCTGTGCCAGGGCATCGGCTTCACCGCCGTGCCGGTCGTGGCGTTCCTGTCCTA
CCTGCTGATCCCGGCGGCGCCCCTCGGCATCGACGGGTGGCGCTGGGTCGTGCTGATCGGTGCCTCGGCGGCGATCGTGG
TCTGGTGGATGCGGGCGGGCCTGCCGGAGAGCCCGCGCTGGCTCGTCGAGCACGGCCGTCTGGCGGAGGCCGAGGCGGTC
CTGCGGCAGCTGGAGGCGCGGATCGCGGCCGAGACCGGCGGCCCGCTTCCCGCACCGGCCGCGCCGGAGCCGGTGCAGCC
GCGCGGCGCGTTCCGCGACCTCTGGGTCCAGCCCTACCGGCGCCGGGCCCTGATGATGGCGGGGTTCAACGTCTTCCAGA
CGGTGGGCTTCTACGGCTTCGCCAACTGGGTGCCGACCCTCCTGGTGGCCCAGGGCATCACGGTGACGTCGAGCCTCGCC
TACACGGCCCTGATCGCGCTCGCCGCCCCGGTCGGGCCCCTGATCGGCCTCGCCATCGCCGACCGGTTCGAGCGCAAGCA
CGTCATCGTGGCCGCCGCCCTCCTCTACATCGCCTGCGGCCTGGCCTTCGCGCAGACGCGGGACGTCGCCGTCATCGTGG
CGCTCGGCATCGGCCTGACGCTGGCCTCGAACGTGATGTCGTACAGCTTCCACGCCTATCAGGCCGAGCTGTTCCCCACG
GGCATCCGCGCCCGGGCGGTCGGCTTCGTCTATTCCTGGAGCCGCTTCTCGGCGATCTTCACCGGCTTCGTCATCGCGTT
CGTGCTGCGGGAGGCCGGGACGCCGGGCGTGTTCCTGTTCATCTCGGCGGCGATGCTGGCCGCGGGCCTGCTCGTCGGGC
TGCTGGGTCCCCGGACGCGGGACGTCGCGCTGGAGAAGATCGCGGGGTGA

Upstream 100 bases:

>100_bases
AGGGTCGCCTCCCGGCCGGCGTCGCGCCCCCTTGCGCGGCGCGCGCTTCCGCGGCACTGCGCCGGCGGGGCGCCGCGGCG
CCGAGACGAGGCTCATCGGC

Downstream 100 bases:

>100_bases
GGCGCGTGAGGAGCACGGCTCCCGGCAAGCCGAATCCGTGCTGGCCTCGGGCATGGTCGCTCAGCCGAGATCCCGGATGA
CGGTCGACGAGTTTCTCGCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MATRTAVRAADEGLDPGAILARLDRLPATPTVWRLVVLLGLGFFFELYDLLFTGYVAPGLVKAGILTPTTPGLFGASGVA
SFVAALFTGLFIGTLACGWLADRFGRRAIFTWSLLSYTAANVVMACQSDAFGLNLWRLIAGIGLGLEMVTIGSYLSELVP
KAIRGRAFALCQGIGFTAVPVVAFLSYLLIPAAPLGIDGWRWVVLIGASAAIVVWWMRAGLPESPRWLVEHGRLAEAEAV
LRQLEARIAAETGGPLPAPAAPEPVQPRGAFRDLWVQPYRRRALMMAGFNVFQTVGFYGFANWVPTLLVAQGITVTSSLA
YTALIALAAPVGPLIGLAIADRFERKHVIVAAALLYIACGLAFAQTRDVAVIVALGIGLTLASNVMSYSFHAYQAELFPT
GIRARAVGFVYSWSRFSAIFTGFVIAFVLREAGTPGVFLFISAAMLAAGLLVGLLGPRTRDVALEKIAG

Sequences:

>Translated_469_residues
MATRTAVRAADEGLDPGAILARLDRLPATPTVWRLVVLLGLGFFFELYDLLFTGYVAPGLVKAGILTPTTPGLFGASGVA
SFVAALFTGLFIGTLACGWLADRFGRRAIFTWSLLSYTAANVVMACQSDAFGLNLWRLIAGIGLGLEMVTIGSYLSELVP
KAIRGRAFALCQGIGFTAVPVVAFLSYLLIPAAPLGIDGWRWVVLIGASAAIVVWWMRAGLPESPRWLVEHGRLAEAEAV
LRQLEARIAAETGGPLPAPAAPEPVQPRGAFRDLWVQPYRRRALMMAGFNVFQTVGFYGFANWVPTLLVAQGITVTSSLA
YTALIALAAPVGPLIGLAIADRFERKHVIVAAALLYIACGLAFAQTRDVAVIVALGIGLTLASNVMSYSFHAYQAELFPT
GIRARAVGFVYSWSRFSAIFTGFVIAFVLREAGTPGVFLFISAAMLAAGLLVGLLGPRTRDVALEKIAG
>Mature_468_residues
ATRTAVRAADEGLDPGAILARLDRLPATPTVWRLVVLLGLGFFFELYDLLFTGYVAPGLVKAGILTPTTPGLFGASGVAS
FVAALFTGLFIGTLACGWLADRFGRRAIFTWSLLSYTAANVVMACQSDAFGLNLWRLIAGIGLGLEMVTIGSYLSELVPK
AIRGRAFALCQGIGFTAVPVVAFLSYLLIPAAPLGIDGWRWVVLIGASAAIVVWWMRAGLPESPRWLVEHGRLAEAEAVL
RQLEARIAAETGGPLPAPAAPEPVQPRGAFRDLWVQPYRRRALMMAGFNVFQTVGFYGFANWVPTLLVAQGITVTSSLAY
TALIALAAPVGPLIGLAIADRFERKHVIVAAALLYIACGLAFAQTRDVAVIVALGIGLTLASNVMSYSFHAYQAELFPTG
IRARAVGFVYSWSRFSAIFTGFVIAFVLREAGTPGVFLFISAAMLAAGLLVGLLGPRTRDVALEKIAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI4506999, Length=400, Percent_Identity=27, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI166064021, Length=386, Percent_Identity=27.720207253886, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI302148518, Length=359, Percent_Identity=25.3481894150418, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI24308167, Length=462, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI203098995, Length=160, Percent_Identity=31.875, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI7662270, Length=346, Percent_Identity=22.8323699421965, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI216548223, Length=320, Percent_Identity=25, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1788068, Length=467, Percent_Identity=29.9785867237687, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788074, Length=458, Percent_Identity=27.0742358078603, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87082159, Length=419, Percent_Identity=28.1622911694511, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786229, Length=458, Percent_Identity=25.1091703056769, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790463, Length=364, Percent_Identity=24.7252747252747, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789207, Length=406, Percent_Identity=25.3694581280788, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789312, Length=401, Percent_Identity=22.4438902743142, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082231, Length=223, Percent_Identity=27.3542600896861, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082404, Length=382, Percent_Identity=20.1570680628272, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321068, Length=227, Percent_Identity=25.1101321585903, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320705, Length=331, Percent_Identity=24.1691842900302, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922616, Length=355, Percent_Identity=23.943661971831, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 49909; Mature: 49778

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRTAVRAADEGLDPGAILARLDRLPATPTVWRLVVLLGLGFFFELYDLLFTGYVAPGL
CCCCHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKAGILTPTTPGLFGASGVASFVAALFTGLFIGTLACGWLADRFGRRAIFTWSLLSYTAA
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
NVVMACQSDAFGLNLWRLIAGIGLGLEMVTIGSYLSELVPKAIRGRAFALCQGIGFTAVP
HHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHH
VVAFLSYLLIPAAPLGIDGWRWVVLIGASAAIVVWWMRAGLPESPRWLVEHGRLAEAEAV
HHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHH
LRQLEARIAAETGGPLPAPAAPEPVQPRGAFRDLWVQPYRRRALMMAGFNVFQTVGFYGF
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANWVPTLLVAQGITVTSSLAYTALIALAAPVGPLIGLAIADRFERKHVIVAAALLYIACG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFAQTRDVAVIVALGIGLTLASNVMSYSFHAYQAELFPTGIRARAVGFVYSWSRFSAIF
HHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TGFVIAFVLREAGTPGVFLFISAAMLAAGLLVGLLGPRTRDVALEKIAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
ATRTAVRAADEGLDPGAILARLDRLPATPTVWRLVVLLGLGFFFELYDLLFTGYVAPGL
CCCHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKAGILTPTTPGLFGASGVASFVAALFTGLFIGTLACGWLADRFGRRAIFTWSLLSYTAA
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
NVVMACQSDAFGLNLWRLIAGIGLGLEMVTIGSYLSELVPKAIRGRAFALCQGIGFTAVP
HHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHH
VVAFLSYLLIPAAPLGIDGWRWVVLIGASAAIVVWWMRAGLPESPRWLVEHGRLAEAEAV
HHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHH
LRQLEARIAAETGGPLPAPAAPEPVQPRGAFRDLWVQPYRRRALMMAGFNVFQTVGFYGF
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANWVPTLLVAQGITVTSSLAYTALIALAAPVGPLIGLAIADRFERKHVIVAAALLYIACG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFAQTRDVAVIVALGIGLTLASNVMSYSFHAYQAELFPTGIRARAVGFVYSWSRFSAIF
HHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TGFVIAFVLREAGTPGVFLFISAAMLAAGLLVGLLGPRTRDVALEKIAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]