Click here to switch to the map view.

The map label for this gene is apaH [H]

Identifier: 170749900

GI number: 170749900

Start: 3716459

End: 3717133

Strand: Direct

Name: apaH [H]

Synonym: Mrad2831_3500

Alternate gene names: 170749900

Gene position: 3716459-3717133 (Clockwise)

Preceding gene: 170749899

Following gene: 170749909

Centisome position: 61.15

GC content: 73.48

Gene sequence:

>675_bases
ATGGATTCGGGCCCCCTCACCTACGCGATCGGCGACGTCCACGGCTGCGCCGCCCTGCTCGACGCGCTGCTGGAGCGGAT
CGCCGGCCATGCCGGCGACCGCCCCCACCGGCTGGTCTTCCTCGGGGACTACATCGACCGCGGTCCGGACAGCGCCGCGG
TGCTCCGCACCGTGAGCCGCCTGAACTGGGCCGAGCCCGAGCGCGTCGTCTGCCTGATGGGCAATCACGAGCGGATGCTG
CTCGACGCGCTCCAGACGGGAAGCGCGGCCGCGCACTGGATGTACAACGGCGGCGAGGCGACGCTCGACGCGTTCGGCGC
GCGGGACCCCGCCGGCCTTCCCCGGGACACCCTCGACTGGATCGAGGCGCTCCCGACGCTGCACGGTGACGGCGCCCACT
GGTACGTGCATGCCGGCCTGCGGCCCGGCGCGGACGCCCGCGATTCGGACGCGCACGATCGCCTGTGGATCCGCGACCCG
TTTCTCGAGGGCGACCACGATTTCGGACGGCACGTGGTCCACGGCCACACGCCGCAACGGAGCGGGCGCCCGGAGGTGCG
CCGGTTCCGTACCAACCTCGACACCGCGGCCGTCTACGGCGGCGCGCTCACCGCCGGGATCTTCTCGGACGCGCAGGGAC
CGGCCCTGGACTTCCTGCAGGTGCGGGCGGGCTGA

Upstream 100 bases:

>100_bases
GGGCAAGTCGGACCTGATCGCGGAGATGCGCGCCCTCGCGGCGTAGCGCGCCCACCCGGGTGGCCTTGCGGAGCGCGACG
CCGCGGTGGACGATGGCGCG

Downstream 100 bases:

>100_bases
GGCTCGGACGCACCGCCGCGGCGGCCGGCGCGACGCCTCCGGCTTCGTCGAGGCCCGGGACTGATCTCAGGCCGCGCGTC
GCGCAGGCACCAGTGCGCAG

Product: metallophosphoesterase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MDSGPLTYAIGDVHGCAALLDALLERIAGHAGDRPHRLVFLGDYIDRGPDSAAVLRTVSRLNWAEPERVVCLMGNHERML
LDALQTGSAAAHWMYNGGEATLDAFGARDPAGLPRDTLDWIEALPTLHGDGAHWYVHAGLRPGADARDSDAHDRLWIRDP
FLEGDHDFGRHVVHGHTPQRSGRPEVRRFRTNLDTAAVYGGALTAGIFSDAQGPALDFLQVRAG

Sequences:

>Translated_224_residues
MDSGPLTYAIGDVHGCAALLDALLERIAGHAGDRPHRLVFLGDYIDRGPDSAAVLRTVSRLNWAEPERVVCLMGNHERML
LDALQTGSAAAHWMYNGGEATLDAFGARDPAGLPRDTLDWIEALPTLHGDGAHWYVHAGLRPGADARDSDAHDRLWIRDP
FLEGDHDFGRHVVHGHTPQRSGRPEVRRFRTNLDTAAVYGGALTAGIFSDAQGPALDFLQVRAG
>Mature_224_residues
MDSGPLTYAIGDVHGCAALLDALLERIAGHAGDRPHRLVFLGDYIDRGPDSAAVLRTVSRLNWAEPERVVCLMGNHERML
LDALQTGSAAAHWMYNGGEATLDAFGARDPAGLPRDTLDWIEALPTLHGDGAHWYVHAGLRPGADARDSDAHDRLWIRDP
FLEGDHDFGRHVVHGHTPQRSGRPEVRRFRTNLDTAAVYGGALTAGIFSDAQGPALDFLQVRAG

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI87081988, Length=206, Percent_Identity=31.5533980582524, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 24337; Mature: 24337

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSGPLTYAIGDVHGCAALLDALLERIAGHAGDRPHRLVFLGDYIDRGPDSAAVLRTVSR
CCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHCCCCCHHHHHHHHHH
LNWAEPERVVCLMGNHERMLLDALQTGSAAAHWMYNGGEATLDAFGARDPAGLPRDTLDW
CCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCCCCCHHHHHH
IEALPTLHGDGAHWYVHAGLRPGADARDSDAHDRLWIRDPFLEGDHDFGRHVVHGHTPQR
HHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEECCCCCCC
SGRPEVRRFRTNLDTAAVYGGALTAGIFSDAQGPALDFLQVRAG
CCCHHHHHHHHCCCHHHHHCCHHHHHHHCCCCCCCEEEEEEECC
>Mature Secondary Structure
MDSGPLTYAIGDVHGCAALLDALLERIAGHAGDRPHRLVFLGDYIDRGPDSAAVLRTVSR
CCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHCCCCCHHHHHHHHHH
LNWAEPERVVCLMGNHERMLLDALQTGSAAAHWMYNGGEATLDAFGARDPAGLPRDTLDW
CCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCCCCCHHHHHH
IEALPTLHGDGAHWYVHAGLRPGADARDSDAHDRLWIRDPFLEGDHDFGRHVVHGHTPQR
HHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEECCCCCCC
SGRPEVRRFRTNLDTAAVYGGALTAGIFSDAQGPALDFLQVRAG
CCCHHHHHHHHCCCHHHHHCCHHHHHHHCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA