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The map label for this gene is aspC [H]

Identifier: 170749874

GI number: 170749874

Start: 3686356

End: 3687537

Strand: Direct

Name: aspC [H]

Synonym: Mrad2831_3474

Alternate gene names: 170749874

Gene position: 3686356-3687537 (Clockwise)

Preceding gene: 170749873

Following gene: 170749878

Centisome position: 60.65

GC content: 70.9

Gene sequence:

>1182_bases
ATGCTGCACGTGGTCCCGGCCTTCTCGCGCATCGGCGAGGAGAACGCCTTCGCGGTTCTGGCTCGGGCCCAGGCCCTCGC
CGCCCAGGGGCGGGACGTGATCAATCTCGGCATCGGCCAGCCGGACATGCCCACGCCCGCCCACGTGGTCGAGGCGGGGA
TCAAGGCGCTGCGCGACGGCCACCACGGCTACACGCCGGCCGTCGGCATCCCGCCGCTCCGCGAGGCGGTGGCCCGCGAC
ATCCACCGCCGCCACGGCGTCGAGGTCTCGCCGGATTCCGTGATGATCGTGCCGGGCGGCAAGGTCACCATGTTCATGGC
GATCCTGATGTTCGGCGCGCCCGGGACCGAGATCCTGTATCCGGACCCCGGCTTCCCGATCTACCGCTCGATGATCGAGT
TCACCGGCGCGACGCCGGTGCCGGTGCCGATCCGCGAGGCGAACGGCTTCGCCTTCTCGGCGGCCGAGACGCTGGCGCTG
ATCACGCCGAGGACGCGGCTGCTGATCGTCAACTCGCCCGCCAACCCCACCGGCGGCGTGACGCCGAAGACCGAGATCGA
CGCCCTGGTGAAGGGCCTCGCCGAGCACCCCGACGTCGCGGTGCTGTCGGACGAAATCTACGGCACCATGACCTACGACG
GCGAGACCCACCACTCGCTGCTGACCTATCCCGAGATCCGCGACCGGCTGGTCTACCTCGACGGCGCGTCCAAGACCTAC
GCGATGACCGGCTGGCGGCTCGGCTGGTCGGTCTGGCCGAAGCCGCTCTACGACGCGGCGCGCAAGCTCGCGGTCAACGC
GCATTCCTGCGTCAACGCGGCGACCCAGTGGGCCGGCATCGCGGCGCTCGACGGCCCGCAGGATTGCGTGGCCGAGATGG
TGGCCGAGTTCGACCGGCGCCGGGCGATCGTGGTCGACGGGCTGAACGCCCTGCCGGACGTCTCCTGCATCGCGCCCAAG
GGCGCGTTCTACGCCTTCCCGAACATCGCCCGGACCGGCTGGAAGGCGAAGGCCCTGGCCTCGGCCCTCCTGGAAGAGAC
GGGCGTGGCCGTGATCGGCGGTCCGGATTTCGGCGTTCACGGCGAGGGCTACCTCCGCCTGTCCTACGCCAACTCGGCCG
AGAACATCCGGCGGGCTCTGGAGCGGATGGGCGCGTTCCTCGGCGAGCGGAAGCCGGGCTGA

Upstream 100 bases:

>100_bases
CCTTCGTGATCCTGGGCGCGATCGCCGTGGCGATGTCGTTCGGCGCGATGAAGCTCTCCGAGCGGTCCAAGCACTGAGAC
CTCACCGCCCGGAGGGCGCG

Downstream 100 bases:

>100_bases
GCGGACGCCCCGTCACCGACCTCGGCAAGGCCATCAGAACCCGTCCCGCGGTCGACGGTAACGGCGCCGCCGTCCCCGCG
AGCGCGGCGCAGCGATCCAG

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MLHVVPAFSRIGEENAFAVLARAQALAAQGRDVINLGIGQPDMPTPAHVVEAGIKALRDGHHGYTPAVGIPPLREAVARD
IHRRHGVEVSPDSVMIVPGGKVTMFMAILMFGAPGTEILYPDPGFPIYRSMIEFTGATPVPVPIREANGFAFSAAETLAL
ITPRTRLLIVNSPANPTGGVTPKTEIDALVKGLAEHPDVAVLSDEIYGTMTYDGETHHSLLTYPEIRDRLVYLDGASKTY
AMTGWRLGWSVWPKPLYDAARKLAVNAHSCVNAATQWAGIAALDGPQDCVAEMVAEFDRRRAIVVDGLNALPDVSCIAPK
GAFYAFPNIARTGWKAKALASALLEETGVAVIGGPDFGVHGEGYLRLSYANSAENIRRALERMGAFLGERKPG

Sequences:

>Translated_393_residues
MLHVVPAFSRIGEENAFAVLARAQALAAQGRDVINLGIGQPDMPTPAHVVEAGIKALRDGHHGYTPAVGIPPLREAVARD
IHRRHGVEVSPDSVMIVPGGKVTMFMAILMFGAPGTEILYPDPGFPIYRSMIEFTGATPVPVPIREANGFAFSAAETLAL
ITPRTRLLIVNSPANPTGGVTPKTEIDALVKGLAEHPDVAVLSDEIYGTMTYDGETHHSLLTYPEIRDRLVYLDGASKTY
AMTGWRLGWSVWPKPLYDAARKLAVNAHSCVNAATQWAGIAALDGPQDCVAEMVAEFDRRRAIVVDGLNALPDVSCIAPK
GAFYAFPNIARTGWKAKALASALLEETGVAVIGGPDFGVHGEGYLRLSYANSAENIRRALERMGAFLGERKPG
>Mature_393_residues
MLHVVPAFSRIGEENAFAVLARAQALAAQGRDVINLGIGQPDMPTPAHVVEAGIKALRDGHHGYTPAVGIPPLREAVARD
IHRRHGVEVSPDSVMIVPGGKVTMFMAILMFGAPGTEILYPDPGFPIYRSMIEFTGATPVPVPIREANGFAFSAAETLAL
ITPRTRLLIVNSPANPTGGVTPKTEIDALVKGLAEHPDVAVLSDEIYGTMTYDGETHHSLLTYPEIRDRLVYLDGASKTY
AMTGWRLGWSVWPKPLYDAARKLAVNAHSCVNAATQWAGIAALDGPQDCVAEMVAEFDRRRAIVVDGLNALPDVSCIAPK
GAFYAFPNIARTGWKAKALASALLEETGVAVIGGPDFGVHGEGYLRLSYANSAENIRRALERMGAFLGERKPG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=340, Percent_Identity=28.5294117647059, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI169881279, Length=340, Percent_Identity=28.5294117647059, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI56713254, Length=316, Percent_Identity=26.2658227848101, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI56713256, Length=316, Percent_Identity=26.2658227848101, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4507369, Length=225, Percent_Identity=29.3333333333333, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI169881281, Length=337, Percent_Identity=24.6290801186944, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI19263340, Length=372, Percent_Identity=26.0752688172043, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI215599424, Length=372, Percent_Identity=26.0752688172043, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=31.6804407713499, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1786816, Length=360, Percent_Identity=28.0555555555556, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=27.2020725388601, Blast_Score=131, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=288, Percent_Identity=28.125, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=288, Percent_Identity=28.125, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=26.4864864864865, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=253, Percent_Identity=27.2727272727273, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=403, Percent_Identity=24.0694789081886, Blast_Score=88, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=23.989898989899, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323118, Length=351, Percent_Identity=23.6467236467236, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573069, Length=401, Percent_Identity=25.6857855361596, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646114, Length=401, Percent_Identity=25.6857855361596, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573067, Length=401, Percent_Identity=25.6857855361596, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573065, Length=401, Percent_Identity=25.6857855361596, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641770, Length=403, Percent_Identity=26.0545905707196, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641760, Length=403, Percent_Identity=26.0545905707196, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641768, Length=403, Percent_Identity=26.0545905707196, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641766, Length=403, Percent_Identity=26.0545905707196, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641764, Length=403, Percent_Identity=26.0545905707196, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45551451, Length=403, Percent_Identity=26.0545905707196, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859735, Length=233, Percent_Identity=25.7510729613734, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42065; Mature: 42065

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHVVPAFSRIGEENAFAVLARAQALAAQGRDVINLGIGQPDMPTPAHVVEAGIKALRDG
CEEEECHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
HHGYTPAVGIPPLREAVARDIHRRHGVEVSPDSVMIVPGGKVTMFMAILMFGAPGTEILY
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHHCCCCCEEEE
PDPGFPIYRSMIEFTGATPVPVPIREANGFAFSAAETLALITPRTRLLIVNSPANPTGGV
CCCCCHHHHHHHHHCCCCCCCCEEECCCCCEEECCCEEEEECCCEEEEEEECCCCCCCCC
TPKTEIDALVKGLAEHPDVAVLSDEIYGTMTYDGETHHSLLTYPEIRDRLVYLDGASKTY
CCCHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCCCEECCCCCCCEEEEEECCCCEE
AMTGWRLGWSVWPKPLYDAARKLAVNAHSCVNAATQWAGIAALDGPQDCVAEMVAEFDRR
EEECEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHCC
RAIVVDGLNALPDVSCIAPKGAFYAFPNIARTGWKAKALASALLEETGVAVIGGPDFGVH
CEEEEECCCCCCCCEEECCCCCEEECCCHHHCCCHHHHHHHHHHHHCCEEEECCCCCCCC
GEGYLRLSYANSAENIRRALERMGAFLGERKPG
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLHVVPAFSRIGEENAFAVLARAQALAAQGRDVINLGIGQPDMPTPAHVVEAGIKALRDG
CEEEECHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
HHGYTPAVGIPPLREAVARDIHRRHGVEVSPDSVMIVPGGKVTMFMAILMFGAPGTEILY
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHHCCCCCEEEE
PDPGFPIYRSMIEFTGATPVPVPIREANGFAFSAAETLALITPRTRLLIVNSPANPTGGV
CCCCCHHHHHHHHHCCCCCCCCEEECCCCCEEECCCEEEEECCCEEEEEEECCCCCCCCC
TPKTEIDALVKGLAEHPDVAVLSDEIYGTMTYDGETHHSLLTYPEIRDRLVYLDGASKTY
CCCHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCCCEECCCCCCCEEEEEECCCCEE
AMTGWRLGWSVWPKPLYDAARKLAVNAHSCVNAATQWAGIAALDGPQDCVAEMVAEFDRR
EEECEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHCC
RAIVVDGLNALPDVSCIAPKGAFYAFPNIARTGWKAKALASALLEETGVAVIGGPDFGVH
CEEEEECCCCCCCCEEECCCCCEEECCCHHHCCCHHHHHHHHHHHHCCEEEECCCCCCCC
GEGYLRLSYANSAENIRRALERMGAFLGERKPG
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]