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The map label for this gene is 170749861

Identifier: 170749861

GI number: 170749861

Start: 3675503

End: 3676405

Strand: Direct

Name: 170749861

Synonym: Mrad2831_3461

Alternate gene names: NA

Gene position: 3675503-3676405 (Clockwise)

Preceding gene: 170749860

Following gene: 170749862

Centisome position: 60.47

GC content: 73.75

Gene sequence:

>903_bases
ATGCTGGTGAGGCGCCACCCGGGGCTCGCCGCCGCGGCCGTGGCCGCGGTTCTGGCCCTCGCACCGGGCGCGGTCCCGGC
CCGGGCCCAGGATGCCTGCCCGGGCCTGTTCGCCGACGGGCGGACGCCGGTCCTCACGAACCCGAAGCTCGCCGTCCGCG
CGGTCCCGCTGTGCTTCGAGGCCTTCGCGGTCCTGCATTCCGGCGTGACGCGCACGCCGCTCTACGCCGCCGAGCACCTC
ACGCGCGCCAGCGTCGCGGCCGCCCGGGCGGTGGCCCGCGACGACGCCTTCCACGAGGAAACCCGGCTGCCGGAGGATCA
GCGCGCCTCGCTGGAGGATTACGTCCGCAGCGGGTTCGACCGGGGCCATCTCGCCCCGGCCGGGGACATGCCGACCCTCA
GTTCCCAGGCCGAGTCGTTCAGCCTCGCCAACATCGTGCCGCAGAACCGCGTCCTGAACCGCGGGCTCTGGGCGGATATC
GAGGAGAGCACCCGGCGCCTGGCCACCCGCCGCGGCGCGCTCTTCGTCGTCACCGGGGTGATCTTCGCGGGCGACGCGGT
GCAGCAGATCAAGGGCGGCGTGCTAGTCCCGACGCAGCTGTTCAAGGCCGTGTACGACCCGTCCCGCGGCGAGGCGGGCG
CCTACCTCGCGCGGAACGACGATTCGAAGGACTGGCGCGCCCTGTCGATCGAGGATCTCCAGCGGGAATCCGGCATCGAC
GTCTTCCCCGGCCTGCCGCCCGCGGCGCGGGCGACCGCGATGAGCCTGCCGGACCCCCATGCCTCCGCCCGCGCGGACGA
GCGCCGGCCCCGCCACGAGCAGACGTGGCAGGAATGGCTCGAGCGCGAACTCACCCGTGCCCTGCGCAAGCTCGTCCGCG
ACTTCCTGCGCACGTTCTTCTGA

Upstream 100 bases:

>100_bases
GCGGCCCGGACCGCGACGCCCGCCCCTTCGGCAACAGCCTCGGCCGGCCCTGCGCGTGGCGGGACCGCCCGACCCCGGAG
GGCGTGCGCCGGGTCCGCGT

Downstream 100 bases:

>100_bases
GAGGACCCGATGCCCGAGGACAAGCGACGCGCCCGGCGCAAGGGCGAGAGCCCGGATGACAAGAGCGGGCGTGACGAGAG
CCCGGCCATCGCGGGCTTCG

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLVRRHPGLAAAAVAAVLALAPGAVPARAQDACPGLFADGRTPVLTNPKLAVRAVPLCFEAFAVLHSGVTRTPLYAAEHL
TRASVAAARAVARDDAFHEETRLPEDQRASLEDYVRSGFDRGHLAPAGDMPTLSSQAESFSLANIVPQNRVLNRGLWADI
EESTRRLATRRGALFVVTGVIFAGDAVQQIKGGVLVPTQLFKAVYDPSRGEAGAYLARNDDSKDWRALSIEDLQRESGID
VFPGLPPAARATAMSLPDPHASARADERRPRHEQTWQEWLERELTRALRKLVRDFLRTFF

Sequences:

>Translated_300_residues
MLVRRHPGLAAAAVAAVLALAPGAVPARAQDACPGLFADGRTPVLTNPKLAVRAVPLCFEAFAVLHSGVTRTPLYAAEHL
TRASVAAARAVARDDAFHEETRLPEDQRASLEDYVRSGFDRGHLAPAGDMPTLSSQAESFSLANIVPQNRVLNRGLWADI
EESTRRLATRRGALFVVTGVIFAGDAVQQIKGGVLVPTQLFKAVYDPSRGEAGAYLARNDDSKDWRALSIEDLQRESGID
VFPGLPPAARATAMSLPDPHASARADERRPRHEQTWQEWLERELTRALRKLVRDFLRTFF
>Mature_300_residues
MLVRRHPGLAAAAVAAVLALAPGAVPARAQDACPGLFADGRTPVLTNPKLAVRAVPLCFEAFAVLHSGVTRTPLYAAEHL
TRASVAAARAVARDDAFHEETRLPEDQRASLEDYVRSGFDRGHLAPAGDMPTLSSQAESFSLANIVPQNRVLNRGLWADI
EESTRRLATRRGALFVVTGVIFAGDAVQQIKGGVLVPTQLFKAVYDPSRGEAGAYLARNDDSKDWRALSIEDLQRESGID
VFPGLPPAARATAMSLPDPHASARADERRPRHEQTWQEWLERELTRALRKLVRDFLRTFF

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI224451073, Length=210, Percent_Identity=30.952380952381, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI224451075, Length=171, Percent_Identity=33.9181286549708, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI53759134, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17505967, Length=212, Percent_Identity=30.6603773584906, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322253, Length=219, Percent_Identity=30.1369863013699, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581065, Length=209, Percent_Identity=30.1435406698565, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI20129899, Length=148, Percent_Identity=33.1081081081081, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: 3.1.30.-

Molecular weight: Translated: 32773; Mature: 32773

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVRRHPGLAAAAVAAVLALAPGAVPARAQDACPGLFADGRTPVLTNPKLAVRAVPLCFE
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AFAVLHSGVTRTPLYAAEHLTRASVAAARAVARDDAFHEETRLPEDQRASLEDYVRSGFD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
RGHLAPAGDMPTLSSQAESFSLANIVPQNRVLNRGLWADIEESTRRLATRRGALFVVTGV
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHH
IFAGDAVQQIKGGVLVPTQLFKAVYDPSRGEAGAYLARNDDSKDWRALSIEDLQRESGID
HHHHHHHHHHCCCEECHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECHHHHHHHCCCC
VFPGLPPAARATAMSLPDPHASARADERRPRHEQTWQEWLERELTRALRKLVRDFLRTFF
CCCCCCCHHHHHHCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLVRRHPGLAAAAVAAVLALAPGAVPARAQDACPGLFADGRTPVLTNPKLAVRAVPLCFE
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AFAVLHSGVTRTPLYAAEHLTRASVAAARAVARDDAFHEETRLPEDQRASLEDYVRSGFD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
RGHLAPAGDMPTLSSQAESFSLANIVPQNRVLNRGLWADIEESTRRLATRRGALFVVTGV
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHH
IFAGDAVQQIKGGVLVPTQLFKAVYDPSRGEAGAYLARNDDSKDWRALSIEDLQRESGID
HHHHHHHHHHCCCEECHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECHHHHHHHCCCC
VFPGLPPAARATAMSLPDPHASARADERRPRHEQTWQEWLERELTRALRKLVRDFLRTFF
CCCCCCCHHHHHHCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]