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The map label for this gene is era [H]

Identifier: 170749854

GI number: 170749854

Start: 3668970

End: 3669968

Strand: Reverse

Name: era [H]

Synonym: Mrad2831_3454

Alternate gene names: 170749854

Gene position: 3669968-3668970 (Counterclockwise)

Preceding gene: 170749855

Following gene: 170749853

Centisome position: 60.38

GC content: 71.97

Gene sequence:

>999_bases
ATGAGCGCGCACGAGCAGGACGATCACGACGAGCGGGACGGGCCCGACAGCGCGCCGGCCCGGGAGCCCGCGCGCGACCC
GTCCACCCTTCCCGGCACGCCCGCCGACGCGCGGGCCGGCTTCGTGGCGCTGATCGGCGTGCCGAATGCCGGCAAGTCGA
CCCTGCTCAACAACCTCGTCGGCACCAAGGTCTCGATCGTCTCGCGCAAGGTGCAGACGACCCGGGCCCTGGTGCGGGGC
ATCCTCATCGAGGGGTCGGCCCAGGTCGTCCTGGTCGACACCCCCGGCATCTTCGCGCCCAAGCGCCGCCTCGACCGCGC
GATGGTGCACTCGGCCTGGAGCGGCGCCGCCGACGCCGACGCCGTCTGCCTGCTGGTCGACGCGCGCAAGGGCGTCGACG
CGGAGGTGGAGGCGGTGCTCGGCCGGCTCGGCGAGGTGAAGCGCGAGAAGCTGCTGATCCTCAACAAGATCGACCTGATC
CCGCGCGAGCGGCTCCTCGATCTCGCCGCGAAGCTCAACGCCGCCGCGCCCTTCGCCGAGACCTTCATGATCTCGGCGCT
GAACGGCGACGGCGTCGCCGACCTGCGCCGGGCGCTGGCCGCCCGCATGCCGCCGGGGCCCTGGCTCTATCCGGAGGATC
AGGTCTCGGACGCGCCCCTGCGCATGCTCGCCGCCGAGATCACCCGCGAGAAGATCTACGACCGGCTGCACGAGGAGCTG
CCCTACCGCTCCACGGTGGAGACCGACCAGTGGCAGATCCGGCCCGACGGCTCCGTGCGGATCGAGCAGACGATCTTCGT
CGAGCGGGAGAGCCAGCGCTCGATCGTGCTCGGCAAGGGCGGCCAGACCATCCGGTCGATCGGGCAGGCGGCCCGGATCG
AGATCGCCGAGGCGGCCGACGCCAAGGTCCACCTGTTCCTGCACGTGAAGGTGCGGGAGAACTGGGCCGACGATCCGGCC
CGCTACCGCGAGATGGGCCTGGAATTCCCGCGGGGCTGA

Upstream 100 bases:

>100_bases
ACGGCACGTCGAAGCGGATCGCCGAGCAGGCCGCCGCCCGGGCGCTGATGGAGCGGGAGGGAATCGGGGCCTCCGCGGAT
GCGGAGCCGACGGAGACAGC

Downstream 100 bases:

>100_bases
CGCGCCGGGTCGCGCGCGGGAGGCTGGGCTTCCCGGCGGGTTCCGGTATAAACGCGGTGTTCCCCCCGGATGAACCGAGT
CGGGCGCGGGTTTACCCCGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSAHEQDDHDERDGPDSAPAREPARDPSTLPGTPADARAGFVALIGVPNAGKSTLLNNLVGTKVSIVSRKVQTTRALVRG
ILIEGSAQVVLVDTPGIFAPKRRLDRAMVHSAWSGAADADAVCLLVDARKGVDAEVEAVLGRLGEVKREKLLILNKIDLI
PRERLLDLAAKLNAAAPFAETFMISALNGDGVADLRRALAARMPPGPWLYPEDQVSDAPLRMLAAEITREKIYDRLHEEL
PYRSTVETDQWQIRPDGSVRIEQTIFVERESQRSIVLGKGGQTIRSIGQAARIEIAEAADAKVHLFLHVKVRENWADDPA
RYREMGLEFPRG

Sequences:

>Translated_332_residues
MSAHEQDDHDERDGPDSAPAREPARDPSTLPGTPADARAGFVALIGVPNAGKSTLLNNLVGTKVSIVSRKVQTTRALVRG
ILIEGSAQVVLVDTPGIFAPKRRLDRAMVHSAWSGAADADAVCLLVDARKGVDAEVEAVLGRLGEVKREKLLILNKIDLI
PRERLLDLAAKLNAAAPFAETFMISALNGDGVADLRRALAARMPPGPWLYPEDQVSDAPLRMLAAEITREKIYDRLHEEL
PYRSTVETDQWQIRPDGSVRIEQTIFVERESQRSIVLGKGGQTIRSIGQAARIEIAEAADAKVHLFLHVKVRENWADDPA
RYREMGLEFPRG
>Mature_331_residues
SAHEQDDHDERDGPDSAPAREPARDPSTLPGTPADARAGFVALIGVPNAGKSTLLNNLVGTKVSIVSRKVQTTRALVRGI
LIEGSAQVVLVDTPGIFAPKRRLDRAMVHSAWSGAADADAVCLLVDARKGVDAEVEAVLGRLGEVKREKLLILNKIDLIP
RERLLDLAAKLNAAAPFAETFMISALNGDGVADLRRALAARMPPGPWLYPEDQVSDAPLRMLAAEITREKIYDRLHEELP
YRSTVETDQWQIRPDGSVRIEQTIFVERESQRSIVLGKGGQTIRSIGQAARIEIAEAADAKVHLFLHVKVRENWADDPAR
YREMGLEFPRG

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=333, Percent_Identity=30.3303303303303, Blast_Score=138, Evalue=7e-33,
Organism=Escherichia coli, GI1788919, Length=298, Percent_Identity=38.9261744966443, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI87082120, Length=176, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646434, Length=339, Percent_Identity=27.7286135693215, Blast_Score=114, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36360; Mature: 36229

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHEQDDHDERDGPDSAPAREPARDPSTLPGTPADARAGFVALIGVPNAGKSTLLNNLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
GTKVSIVSRKVQTTRALVRGILIEGSAQVVLVDTPGIFAPKRRLDRAMVHSAWSGAADAD
CCHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
AVCLLVDARKGVDAEVEAVLGRLGEVKREKLLILNKIDLIPRERLLDLAAKLNAAAPFAE
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEHHHCCCCHHHHHHHHHHHCCCCCHHH
TFMISALNGDGVADLRRALAARMPPGPWLYPEDQVSDAPLRMLAAEITREKIYDRLHEEL
HHEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
PYRSTVETDQWQIRPDGSVRIEQTIFVERESQRSIVLGKGGQTIRSIGQAARIEIAEAAD
CCCCCCCCCCEEECCCCCEEEEEEEEEEECCCCEEEEECCCHHHHHHHHHHEEEEECCCC
AKVHLFLHVKVRENWADDPARYREMGLEFPRG
CEEEEEEEEEEECCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAHEQDDHDERDGPDSAPAREPARDPSTLPGTPADARAGFVALIGVPNAGKSTLLNNLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
GTKVSIVSRKVQTTRALVRGILIEGSAQVVLVDTPGIFAPKRRLDRAMVHSAWSGAADAD
CCHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
AVCLLVDARKGVDAEVEAVLGRLGEVKREKLLILNKIDLIPRERLLDLAAKLNAAAPFAE
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEHHHCCCCHHHHHHHHHHHCCCCCHHH
TFMISALNGDGVADLRRALAARMPPGPWLYPEDQVSDAPLRMLAAEITREKIYDRLHEEL
HHEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
PYRSTVETDQWQIRPDGSVRIEQTIFVERESQRSIVLGKGGQTIRSIGQAARIEIAEAAD
CCCCCCCCCCEEECCCCCEEEEEEEEEEECCCCEEEEECCCHHHHHHHHHHEEEEECCCC
AKVHLFLHVKVRENWADDPARYREMGLEFPRG
CEEEEEEEEEEECCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA