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The map label for this gene is yaeL [C]

Identifier: 170749840

GI number: 170749840

Start: 3655520

End: 3656674

Strand: Reverse

Name: yaeL [C]

Synonym: Mrad2831_3440

Alternate gene names: 170749840

Gene position: 3656674-3655520 (Counterclockwise)

Preceding gene: 170749841

Following gene: 170749839

Centisome position: 60.16

GC content: 70.13

Gene sequence:

>1155_bases
ATGGACTTCCTCAACGCGATGGGCGGGACCGCCGGCGGTTTCTTCGGTGCCGTGATCCCGTTCCTGTTCGTGCTCACCGT
CGTGGTGTTCGTGCACGAGATGGGCCACTTCCTGGTCGGGCGCTGGTGCGGGGTCGGCGTGCACGCCTTCTCGCTCGGCT
TCGGCCCCGAGCTGTTCGGCTTCAACGACCGGCGCGGCACCCGCTGGAAGGTCTGCGCGATCCCGCTCGGCGGCTACGTG
AAGTTCCACGGCGACGTGAACGGCGCCAGCATGCCGGATCCGGAGGCCGTCGCCCGGATGAGCCCGCAGGAGCGGGCGAT
CAGCTTCCCGACCCAGCCCGTGTCGAAGCGCGCCGCGATCGTCGCCGCGGGCCCGGTGGCGAACTTCATCCTGGCGATCC
TGCTCTTCGCGGGCGCCATCTGGCTCGGCGGCCGCTACGAGCTGCCCGCCCGGGTCTCGTCGGTGGAGCCGAACAGCGTC
GCCGCCCAGGCCGGCTTCCAGCCCGGCGACGTGATCACCGCCATCGACGGCGAGAAGATCGGCGACTTCAACGCCATGTA
CCGCACGGTCACCGGCAGCGCCGGGACGCCGCTGACCTTCACGGTGGAGCGCAACGACCAGCCCATCACCATCCAGGCGA
CGCCGGCGACCTTCGAGGAGAAGACGCCGTTCGGCCGCCACCGGATCGGCCGGCTCGGCATCCGCTCCCCCGCGGGCTCG
GAGGCGCGGCTCGTGCATTACGGCGCGCTCGACTCGCTCAATCTCGGCGTGAAGGAGACCTACTTCGTCGTCGAGCGCAC
CTTCTCGTATCTCGGCAAGCTCGTGACCGGCCGGGAATCCGCCGACCAGCTCTCGGGTCCGATCGGCATCGCCCGCGTCT
CCGGCGAGGTCGCCAAGACCGGCGGCGTCGGCGGTCTGGTCGGGCTGATCGCCCTGCTCTCCGTCTCGATCGGCCTGCTC
AACCTGTTCCCGGTGCCGCTGCTCGATGGCGGCCACCTGCTGTTCTACGCCTTCGAGGTGGTGCGCGGCCGCCCGCTCAG
CGAGCGGGCCCAGGAGATCGGCTTCCGCATCGGCCTCGCCCTGGTGCTGATGCTGATGCTGTTCGCCGCCTGGAACGACA
TCCTCAACCTCGGCGCCTCCTGGCGGAACACCTGA

Upstream 100 bases:

>100_bases
GAGCCGCAGGATTGCGTTGGCGGTCGGCACCGCCGATCTGCTAGACAGGGCGGATGGCCGGCCCGAGAAGCCGGCGCCGA
GACGGCCAGGAATACGGCTT

Downstream 100 bases:

>100_bases
TCCGGGGCCGGCGGGGATCCCGGGATCCCCGCCGGATCTCCACCGGAAACGCTGCCCCAATCCCGCCGCGATCTCGCCCG
GACACCGCCCGGATGACGCC

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MDFLNAMGGTAGGFFGAVIPFLFVLTVVVFVHEMGHFLVGRWCGVGVHAFSLGFGPELFGFNDRRGTRWKVCAIPLGGYV
KFHGDVNGASMPDPEAVARMSPQERAISFPTQPVSKRAAIVAAGPVANFILAILLFAGAIWLGGRYELPARVSSVEPNSV
AAQAGFQPGDVITAIDGEKIGDFNAMYRTVTGSAGTPLTFTVERNDQPITIQATPATFEEKTPFGRHRIGRLGIRSPAGS
EARLVHYGALDSLNLGVKETYFVVERTFSYLGKLVTGRESADQLSGPIGIARVSGEVAKTGGVGGLVGLIALLSVSIGLL
NLFPVPLLDGGHLLFYAFEVVRGRPLSERAQEIGFRIGLALVLMLMLFAAWNDILNLGASWRNT

Sequences:

>Translated_384_residues
MDFLNAMGGTAGGFFGAVIPFLFVLTVVVFVHEMGHFLVGRWCGVGVHAFSLGFGPELFGFNDRRGTRWKVCAIPLGGYV
KFHGDVNGASMPDPEAVARMSPQERAISFPTQPVSKRAAIVAAGPVANFILAILLFAGAIWLGGRYELPARVSSVEPNSV
AAQAGFQPGDVITAIDGEKIGDFNAMYRTVTGSAGTPLTFTVERNDQPITIQATPATFEEKTPFGRHRIGRLGIRSPAGS
EARLVHYGALDSLNLGVKETYFVVERTFSYLGKLVTGRESADQLSGPIGIARVSGEVAKTGGVGGLVGLIALLSVSIGLL
NLFPVPLLDGGHLLFYAFEVVRGRPLSERAQEIGFRIGLALVLMLMLFAAWNDILNLGASWRNT
>Mature_384_residues
MDFLNAMGGTAGGFFGAVIPFLFVLTVVVFVHEMGHFLVGRWCGVGVHAFSLGFGPELFGFNDRRGTRWKVCAIPLGGYV
KFHGDVNGASMPDPEAVARMSPQERAISFPTQPVSKRAAIVAAGPVANFILAILLFAGAIWLGGRYELPARVSSVEPNSV
AAQAGFQPGDVITAIDGEKIGDFNAMYRTVTGSAGTPLTFTVERNDQPITIQATPATFEEKTPFGRHRIGRLGIRSPAGS
EARLVHYGALDSLNLGVKETYFVVERTFSYLGKLVTGRESADQLSGPIGIARVSGEVAKTGGVGGLVGLIALLSVSIGLL
NLFPVPLLDGGHLLFYAFEVVRGRPLSERAQEIGFRIGLALVLMLMLFAAWNDILNLGASWRNT

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=230, Percent_Identity=38.2608695652174, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40953; Mature: 40953

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLNAMGGTAGGFFGAVIPFLFVLTVVVFVHEMGHFLVGRWCGVGVHAFSLGFGPELFG
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCC
FNDRRGTRWKVCAIPLGGYVKFHGDVNGASMPDPEAVARMSPQERAISFPTQPVSKRAAI
CCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHCCCHHHHCCCCCCCCCCCEEE
VAAGPVANFILAILLFAGAIWLGGRYELPARVSSVEPNSVAAQAGFQPGDVITAIDGEKI
EECCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCC
GDFNAMYRTVTGSAGTPLTFTVERNDQPITIQATPATFEEKTPFGRHRIGRLGIRSPAGS
CCHHHHHEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCC
EARLVHYGALDSLNLGVKETYFVVERTFSYLGKLVTGRESADQLSGPIGIARVSGEVAKT
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCHHHC
GGVGGLVGLIALLSVSIGLLNLFPVPLLDGGHLLFYAFEVVRGRPLSERAQEIGFRIGLA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LVLMLMLFAAWNDILNLGASWRNT
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDFLNAMGGTAGGFFGAVIPFLFVLTVVVFVHEMGHFLVGRWCGVGVHAFSLGFGPELFG
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCC
FNDRRGTRWKVCAIPLGGYVKFHGDVNGASMPDPEAVARMSPQERAISFPTQPVSKRAAI
CCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHCCCHHHHCCCCCCCCCCCEEE
VAAGPVANFILAILLFAGAIWLGGRYELPARVSSVEPNSVAAQAGFQPGDVITAIDGEKI
EECCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCC
GDFNAMYRTVTGSAGTPLTFTVERNDQPITIQATPATFEEKTPFGRHRIGRLGIRSPAGS
CCHHHHHEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCC
EARLVHYGALDSLNLGVKETYFVVERTFSYLGKLVTGRESADQLSGPIGIARVSGEVAKT
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCHHHC
GGVGGLVGLIALLSVSIGLLNLFPVPLLDGGHLLFYAFEVVRGRPLSERAQEIGFRIGLA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LVLMLMLFAAWNDILNLGASWRNT
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]