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The map label for this gene is atoS [H]

Identifier: 170749823

GI number: 170749823

Start: 3634777

End: 3636240

Strand: Direct

Name: atoS [H]

Synonym: Mrad2831_3423

Alternate gene names: 170749823

Gene position: 3634777-3636240 (Clockwise)

Preceding gene: 170749822

Following gene: 170749824

Centisome position: 59.8

GC content: 74.86

Gene sequence:

>1464_bases
GTGACGGCCTACAGCCTGCGCGCCCGGCTGCTCGCGCTCTGGGTCCTGCTGCTCGCCTCCGCGGCCGCGACCGCCTACCT
GATGCTCGGCGTCTACGACCAGTCGACGGGTGTCCAGGTGGCGCAGGCCGACCTCGCGGTCGGGCGGGCCTGCCGCGAGA
TCATCGACCGGTACGCCGCCCTGGTCCGGGCCCGCGGCAAGGGTAGCGCAGAGGCCGACCTGGTCGGCACCCTGTCGACC
GCGCTGGCGCGCTTCCCGGGCCTCGAGGGCGGGATCTGGAGCGCCGCCCGCGGATCCGTGGCCTACGCCTATCCGACCTA
CGAGGGATCCGGGCCGAAGACCGACTTTCCGGCGGCCGAGCGCGACGCCATCGCGGCGCTGAACGCGCAGGCGCTGCGGG
TCGACCACGCGATCTCGGAGCGCCGGCCGAGCCGGACCCAGGTCCTGATGCTCCAGGCCTGTCCCCTTCACGGGCCGGAG
GCCGGCCTGACCGCGTGGTCGATGACGCGCGCGCACGTCAACGACGGCCCCACCTACACGCGCTTCCTCGCGGGCCTCGG
CTTCCTGGCCGTGACGGTGCTCGGATCGGCCGCGTTCCTGAGCTGGTTCCTGTACGGGTTCTCAGGGCGGATCGCCCGGC
TGGAGGCCGCGCTCGCCGCGCCGCGCCCGGACGGCCAGGATCTGCCCCATCTCGACCGCACCGGCGAGCGCGAACTCGAC
CGGCTGGTGGACGCCCTGAACGCCGCCGGCGGGCGGCTGCGGGAGGCTCAGGCGCGCATCGTGGCGACCGAGCGACTGGC
CGCCGTCGGCCGGCTGGCGGCGAGCGTCGCCCACGAGATCCGCAATCCCATCGCGGCGATGCGCCTGAAAGCCGAGAACG
CCCTGGTCAGCGGCGATCCCCACCGGACCGCCGCCGCCCTCGAGGCGGTGCTCGGCCAGATCGCCCGGGTCGACACGCTG
CTGCGCGACCTCCTCAACCTGACCCAGGCGCGGCCGCTCAACCGGATGCCCACGCCGGTAGAGCCGCTCCTGGCCGAGTG
CGCGCACCTGCACGAGGAGCTGGCGAGCGCGCGGTCGGTCCGGATCGCGGTCGCCGCCGACGGGCTGCCCGCCACGGACC
ATCCGCATCTCGACCGGGCGCAGATCGCCCGGGCCGTCGACAACCTGCTGCTGAACGCCCTGCAGCACGCGCCGCCGGGC
GGCCGGATCCGCCTCGGTGCCGAGCGGGCGACGGTCGACGGCGCGCTGCGGCTGCGCCTCAGCGTCGCCGATACCGGCGC
CGGCGTCGATCCGGTGATCCGCGCCGGCCTGTTCGAGCCGTTCGTCACCGGCCGGCCCGACGGGACCGGCCTCGGGCTCG
CGATCGTGCGCGAGATCGCCCTGGCCCATCGGGGCGAGGCGAGGCTGGTCGAGGGCGCTCCGGAGACCACCTTTGTCCTG
GACCTGCCATGGCAACCATCCTGA

Upstream 100 bases:

>100_bases
CGCGTCGTCGAGTGGTCACGGGGCCGGGCCTTGGCGTAGGAACGGGGTCCGGGCGCGACGCCGCCGCAGGAGCCAGCGCC
ATGCCGGGTCGGACACCGCC

Downstream 100 bases:

>100_bases
TCGTCGACGACGACAGAGCCCTGCGCGACGGGCTCGCCGAGACGGTGACCGATCTCGGGCACACCGCGCTCCCGGTCGCC
TCCGGCTCGGAGGCCCTGGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MTAYSLRARLLALWVLLLASAAATAYLMLGVYDQSTGVQVAQADLAVGRACREIIDRYAALVRARGKGSAEADLVGTLST
ALARFPGLEGGIWSAARGSVAYAYPTYEGSGPKTDFPAAERDAIAALNAQALRVDHAISERRPSRTQVLMLQACPLHGPE
AGLTAWSMTRAHVNDGPTYTRFLAGLGFLAVTVLGSAAFLSWFLYGFSGRIARLEAALAAPRPDGQDLPHLDRTGERELD
RLVDALNAAGGRLREAQARIVATERLAAVGRLAASVAHEIRNPIAAMRLKAENALVSGDPHRTAAALEAVLGQIARVDTL
LRDLLNLTQARPLNRMPTPVEPLLAECAHLHEELASARSVRIAVAADGLPATDHPHLDRAQIARAVDNLLLNALQHAPPG
GRIRLGAERATVDGALRLRLSVADTGAGVDPVIRAGLFEPFVTGRPDGTGLGLAIVREIALAHRGEARLVEGAPETTFVL
DLPWQPS

Sequences:

>Translated_487_residues
MTAYSLRARLLALWVLLLASAAATAYLMLGVYDQSTGVQVAQADLAVGRACREIIDRYAALVRARGKGSAEADLVGTLST
ALARFPGLEGGIWSAARGSVAYAYPTYEGSGPKTDFPAAERDAIAALNAQALRVDHAISERRPSRTQVLMLQACPLHGPE
AGLTAWSMTRAHVNDGPTYTRFLAGLGFLAVTVLGSAAFLSWFLYGFSGRIARLEAALAAPRPDGQDLPHLDRTGERELD
RLVDALNAAGGRLREAQARIVATERLAAVGRLAASVAHEIRNPIAAMRLKAENALVSGDPHRTAAALEAVLGQIARVDTL
LRDLLNLTQARPLNRMPTPVEPLLAECAHLHEELASARSVRIAVAADGLPATDHPHLDRAQIARAVDNLLLNALQHAPPG
GRIRLGAERATVDGALRLRLSVADTGAGVDPVIRAGLFEPFVTGRPDGTGLGLAIVREIALAHRGEARLVEGAPETTFVL
DLPWQPS
>Mature_486_residues
TAYSLRARLLALWVLLLASAAATAYLMLGVYDQSTGVQVAQADLAVGRACREIIDRYAALVRARGKGSAEADLVGTLSTA
LARFPGLEGGIWSAARGSVAYAYPTYEGSGPKTDFPAAERDAIAALNAQALRVDHAISERRPSRTQVLMLQACPLHGPEA
GLTAWSMTRAHVNDGPTYTRFLAGLGFLAVTVLGSAAFLSWFLYGFSGRIARLEAALAAPRPDGQDLPHLDRTGERELDR
LVDALNAAGGRLREAQARIVATERLAAVGRLAASVAHEIRNPIAAMRLKAENALVSGDPHRTAAALEAVLGQIARVDTLL
RDLLNLTQARPLNRMPTPVEPLLAECAHLHEELASARSVRIAVAADGLPATDHPHLDRAQIARAVDNLLLNALQHAPPGG
RIRLGAERATVDGALRLRLSVADTGAGVDPVIRAGLFEPFVTGRPDGTGLGLAIVREIALAHRGEARLVEGAPETTFVLD
LPWQPS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=29.8387096774194, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=30.4721030042918, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=29.7709923664122, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787894, Length=285, Percent_Identity=29.4736842105263, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790861, Length=277, Percent_Identity=29.6028880866426, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081816, Length=296, Percent_Identity=31.0810810810811, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=243, Percent_Identity=31.6872427983539, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=27.9835390946502, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51647; Mature: 51516

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYSLRARLLALWVLLLASAAATAYLMLGVYDQSTGVQVAQADLAVGRACREIIDRYAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LVRARGKGSAEADLVGTLSTALARFPGLEGGIWSAARGSVAYAYPTYEGSGPKTDFPAAE
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCH
RDAIAALNAQALRVDHAISERRPSRTQVLMLQACPLHGPEAGLTAWSMTRAHVNDGPTYT
HHHHHHHCHHHHHHHHHHHHCCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHH
RFLAGLGFLAVTVLGSAAFLSWFLYGFSGRIARLEAALAAPRPDGQDLPHLDRTGERELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
RLVDALNAAGGRLREAQARIVATERLAAVGRLAASVAHEIRNPIAAMRLKAENALVSGDP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEECCCC
HRTAAALEAVLGQIARVDTLLRDLLNLTQARPLNRMPTPVEPLLAECAHLHEELASARSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCE
RIAVAADGLPATDHPHLDRAQIARAVDNLLLNALQHAPPGGRIRLGAERATVDGALRLRL
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCCEEEEEE
SVADTGAGVDPVIRAGLFEPFVTGRPDGTGLGLAIVREIALAHRGEARLVEGAPETTFVL
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCEEEE
DLPWQPS
ECCCCCC
>Mature Secondary Structure 
TAYSLRARLLALWVLLLASAAATAYLMLGVYDQSTGVQVAQADLAVGRACREIIDRYAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LVRARGKGSAEADLVGTLSTALARFPGLEGGIWSAARGSVAYAYPTYEGSGPKTDFPAAE
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCH
RDAIAALNAQALRVDHAISERRPSRTQVLMLQACPLHGPEAGLTAWSMTRAHVNDGPTYT
HHHHHHHCHHHHHHHHHHHHCCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHH
RFLAGLGFLAVTVLGSAAFLSWFLYGFSGRIARLEAALAAPRPDGQDLPHLDRTGERELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
RLVDALNAAGGRLREAQARIVATERLAAVGRLAASVAHEIRNPIAAMRLKAENALVSGDP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEECCCC
HRTAAALEAVLGQIARVDTLLRDLLNLTQARPLNRMPTPVEPLLAECAHLHEELASARSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCE
RIAVAADGLPATDHPHLDRAQIARAVDNLLLNALQHAPPGGRIRLGAERATVDGALRLRL
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCCEEEEEE
SVADTGAGVDPVIRAGLFEPFVTGRPDGTGLGLAIVREIALAHRGEARLVEGAPETTFVL
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCEEEE
DLPWQPS
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]