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The map label for this gene is moxY [H]

Identifier: 170749795

GI number: 170749795

Start: 3602471

End: 3603952

Strand: Reverse

Name: moxY [H]

Synonym: Mrad2831_3394

Alternate gene names: 170749795

Gene position: 3603952-3602471 (Counterclockwise)

Preceding gene: 170749797

Following gene: 170749794

Centisome position: 59.3

GC content: 73.62

Gene sequence:

>1482_bases
ATGGACTTCGCCGGCGCGGTCGCTATGCGTCACCGCGTGGATACCCGCCCGAACCTGCCCCCGCGTTCCGAGACGGCCGC
CGCGCCGGACGGCCCGCGGCTCCGCCGCTGGCCCTGGTCGGCGTGGTCCACCCGCGCGCGGCTCGTCGCGGTGGTCCTGC
TCATCGACGCCTTCGCGGCCGTGATTTCCTGCGCGGTCATCGTGCTGAACGCCCGGTCGGCGGTGCGCGTCGAGACCCGC
GCGTCACTCGCCACCGTCGAGTCTCTGGTGGCCGACACGATCCGCCTGTCGGACACGGCCGCGCCCGACACGCTGCTCCA
GACCCTCGACCTGCGCTTCAAGGTCCTGCGACACGTCCGGGTCGCGGTGCTCGACGCGGACGGCGACCAGGTCGGCCGGC
CGCTGCCGCCCCCGCGCGCCGACCGGGAGGCGCCGCACTGGTTCGCCGACCTGATCATGCCGCCGATCGAGCGCCACGTC
CTGCCGATCGTCGTCAACGGGCATCGGCTCGGCACGGCGCAGATCACCACGCAGCCGATGGACGAGATCGACGAGATCTG
GGGCTACGCCCGGGCGCTCTCGCTCACCACTTTGGCGATCAACGCCGCGATGCTGATCGCCCTCTACATCGCGCTGGGCC
GGATCCTCGCGCCGCTGCGGCGGCTCGGCGCCGGCCTGACCCAGCTGGAGCATCACGACTACACCGCCCGCCTGGAGCCG
CCCGGCGCGCGGGAGCTGGCGGTGATCGCCGAGCGGTTCAACAAGGTCGCCGAGGCCCTGGGCGAGGTCCGGGCCGCCAA
CGGCCGCCTCAACCGCCAACTCCTGACCGTGCAGGACGACGAGCGCCGCCGGACGGCCCTGGAGCTGCACGACGAGTTCG
GCCCGTGCCTGTTCGCCCTGGAGGCGAACGCGGCCTCGATCGGCCGCATCGCCTCCGGTGCGGCCGAGCCGAGCCGCGAG
AAGCTCGCCGCCCGGGCGGCCGAGATCAGCGCCATCGTCGGGCAGGTCCAGACCGTCAACCGGGAACTCCTGAACCGCCT
GCGACCGCACGGCCTCGGGCAGGCGCCCCTGGCGACCTGCCTCGACCTGCTCCTGCGCGGCTTCGGGCAGCGCCATCCCG
GCATCACCTTCGCGGGCCGGTTCGACGGGCTGGCCCGGGGCTACGGCGACCTCGTGGACCTCACGGTGTTCCGCTGCGTG
CAGGAGAGCGCGACCAACGCCGTGCGGCACGGCGCCGCGACCCGGGTAGAGGCGGAGGCGGCCGAGACCGGCGGCCGGAT
CGACCTCACCATCCGCGACAACGGCACCGGCATCCCGCCGGAACACGGCACCGGCCTCGGTCTGTCGGGGATGCGCGAGC
GTGTGGAGGCCCTCGACGGCACCTTCGCCCTTGACAATGCCGGCCCCGGGGCGATCGTCCGGATCACGATCCCCGTTCCG
CCTGACCGGGGCGACGAGAACAACACCGCGCCGAGCGCATGA

Upstream 100 bases:

>100_bases
GCCGCTTAAGATTCGGTGTTCGGGCCGTCGGCGCCGGTGCGGGCGGTGCGACCCGAGCGCGTTCGGGCCGGCAGCCCGCG
CGCCGCCCGCCGCGGGCACG

Downstream 100 bases:

>100_bases
ACGCCATCGCATCCCAGATCGACGCCGCCGCCACCCGCCTGCCGGTCCTCGTCATCGATGATCACCCCATCGTCCTGCAG
GGCTGTCGACGGGTGCTGGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MDFAGAVAMRHRVDTRPNLPPRSETAAAPDGPRLRRWPWSAWSTRARLVAVVLLIDAFAAVISCAVIVLNARSAVRVETR
ASLATVESLVADTIRLSDTAAPDTLLQTLDLRFKVLRHVRVAVLDADGDQVGRPLPPPRADREAPHWFADLIMPPIERHV
LPIVVNGHRLGTAQITTQPMDEIDEIWGYARALSLTTLAINAAMLIALYIALGRILAPLRRLGAGLTQLEHHDYTARLEP
PGARELAVIAERFNKVAEALGEVRAANGRLNRQLLTVQDDERRRTALELHDEFGPCLFALEANAASIGRIASGAAEPSRE
KLAARAAEISAIVGQVQTVNRELLNRLRPHGLGQAPLATCLDLLLRGFGQRHPGITFAGRFDGLARGYGDLVDLTVFRCV
QESATNAVRHGAATRVEAEAAETGGRIDLTIRDNGTGIPPEHGTGLGLSGMRERVEALDGTFALDNAGPGAIVRITIPVP
PDRGDENNTAPSA

Sequences:

>Translated_493_residues
MDFAGAVAMRHRVDTRPNLPPRSETAAAPDGPRLRRWPWSAWSTRARLVAVVLLIDAFAAVISCAVIVLNARSAVRVETR
ASLATVESLVADTIRLSDTAAPDTLLQTLDLRFKVLRHVRVAVLDADGDQVGRPLPPPRADREAPHWFADLIMPPIERHV
LPIVVNGHRLGTAQITTQPMDEIDEIWGYARALSLTTLAINAAMLIALYIALGRILAPLRRLGAGLTQLEHHDYTARLEP
PGARELAVIAERFNKVAEALGEVRAANGRLNRQLLTVQDDERRRTALELHDEFGPCLFALEANAASIGRIASGAAEPSRE
KLAARAAEISAIVGQVQTVNRELLNRLRPHGLGQAPLATCLDLLLRGFGQRHPGITFAGRFDGLARGYGDLVDLTVFRCV
QESATNAVRHGAATRVEAEAAETGGRIDLTIRDNGTGIPPEHGTGLGLSGMRERVEALDGTFALDNAGPGAIVRITIPVP
PDRGDENNTAPSA
>Mature_493_residues
MDFAGAVAMRHRVDTRPNLPPRSETAAAPDGPRLRRWPWSAWSTRARLVAVVLLIDAFAAVISCAVIVLNARSAVRVETR
ASLATVESLVADTIRLSDTAAPDTLLQTLDLRFKVLRHVRVAVLDADGDQVGRPLPPPRADREAPHWFADLIMPPIERHV
LPIVVNGHRLGTAQITTQPMDEIDEIWGYARALSLTTLAINAAMLIALYIALGRILAPLRRLGAGLTQLEHHDYTARLEP
PGARELAVIAERFNKVAEALGEVRAANGRLNRQLLTVQDDERRRTALELHDEFGPCLFALEANAASIGRIASGAAEPSRE
KLAARAAEISAIVGQVQTVNRELLNRLRPHGLGQAPLATCLDLLLRGFGQRHPGITFAGRFDGLARGYGDLVDLTVFRCV
QESATNAVRHGAATRVEAEAAETGGRIDLTIRDNGTGIPPEHGTGLGLSGMRERVEALDGTFALDNAGPGAIVRITIPVP
PDRGDENNTAPSA

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression. May function as a membrane-associated protein kinase that phosphorylates moxX in response to environmental signals [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=229, Percent_Identity=29.2576419213974, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR011712 [H]

Pfam domain/function: PF00672 HAMP; PF07730 HisKA_3 [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 53134; Mature: 53134

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFAGAVAMRHRVDTRPNLPPRSETAAAPDGPRLRRWPWSAWSTRARLVAVVLLIDAFAA
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VISCAVIVLNARSAVRVETRASLATVESLVADTIRLSDTAAPDTLLQTLDLRFKVLRHVR
HHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHE
VAVLDADGDQVGRPLPPPRADREAPHWFADLIMPPIERHVLPIVVNGHRLGTAQITTQPM
EEEEECCCHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHCEEEEEECCCEECEEEECCCCH
DEIDEIWGYARALSLTTLAINAAMLIALYIALGRILAPLRRLGAGLTQLEHHDYTARLEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECC
PGARELAVIAERFNKVAEALGEVRAANGRLNRQLLTVQDDERRRTALELHDEFGPCLFAL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEE
EANAASIGRIASGAAEPSREKLAARAAEISAIVGQVQTVNRELLNRLRPHGLGQAPLATC
ECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LDLLLRGFGQRHPGITFAGRFDGLARGYGDLVDLTVFRCVQESATNAVRHGAATRVEAEA
HHHHHHHCCCCCCCCEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHH
AETGGRIDLTIRDNGTGIPPEHGTGLGLSGMRERVEALDGTFALDNAGPGAIVRITIPVP
HHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECC
PDRGDENNTAPSA
CCCCCCCCCCCCC
>Mature Secondary Structure
MDFAGAVAMRHRVDTRPNLPPRSETAAAPDGPRLRRWPWSAWSTRARLVAVVLLIDAFAA
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VISCAVIVLNARSAVRVETRASLATVESLVADTIRLSDTAAPDTLLQTLDLRFKVLRHVR
HHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHE
VAVLDADGDQVGRPLPPPRADREAPHWFADLIMPPIERHVLPIVVNGHRLGTAQITTQPM
EEEEECCCHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHCEEEEEECCCEECEEEECCCCH
DEIDEIWGYARALSLTTLAINAAMLIALYIALGRILAPLRRLGAGLTQLEHHDYTARLEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECC
PGARELAVIAERFNKVAEALGEVRAANGRLNRQLLTVQDDERRRTALELHDEFGPCLFAL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEE
EANAASIGRIASGAAEPSREKLAARAAEISAIVGQVQTVNRELLNRLRPHGLGQAPLATC
ECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LDLLLRGFGQRHPGITFAGRFDGLARGYGDLVDLTVFRCVQESATNAVRHGAATRVEAEA
HHHHHHHCCCCCCCCEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHH
AETGGRIDLTIRDNGTGIPPEHGTGLGLSGMRERVEALDGTFALDNAGPGAIVRITIPVP
HHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECC
PDRGDENNTAPSA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]