Click here to switch to the map view.

The map label for this gene is minC [H]

Identifier: 170749776

GI number: 170749776

Start: 3581933

End: 3582661

Strand: Reverse

Name: minC [H]

Synonym: Mrad2831_3375

Alternate gene names: 170749776

Gene position: 3582661-3581933 (Counterclockwise)

Preceding gene: 170749777

Following gene: 170749775

Centisome position: 58.95

GC content: 72.29

Gene sequence:

>729_bases
ATGAGCGACACCCTCCCCGAGCCGATCGATCCGGAGACCGCCCGCGCGGCGGCTCCTTCCGCGCCCCGGCCGCTCAGCCT
GCGCGGACGGGCCTTCAAGGCCCTGGCCCTCTGCCCCGAGCCGCCGCTTCCGGAGTGGCTCGCGGGACTCGACGCGGCGC
TCAAGCGCTCGCCGACCCTGCTGAAAGGCCGGGCCGTCATCCTGGACTGCGCCCAGCTCAAGCCCGAGCCGGACGCGCTC
GAGACGCTCATGAACGAGCTCAAGGCCCGCGGCATCGCGGTCCTGGGCATCGAGGGTGCCGACGCGGTCGCGGACGGTCT
GCCGCCGCTGCTGGTCAAGGGGCACCCGTCCGAGAAGGTCGAGATCCCGAGCGTCCCGGCCGAGCCGGAGCCGCAGGTGG
TCACCTCGATCACCGTCGAGGGCTCGGTCCGCTCCGGCCAGAGCGTCATCAACCCGACCGGCGACGTCACCGTGATGGGG
TCGGTCTCCTCCGGGGCCGAGATCCTGGCCGGCGGCTCCATCCACGTCTACGGCGCCCTGCGCGGTCGCGCGATCGCCGG
AGCCGCGCGCAACCCGCGCGCACGAATCTACTGCCGCAAATTCGAGCCCGAGTTGCTGGGGATCGACCGCCTCGTGCGGA
CGGCGGAGGACATGGGCACGGCCCTGCGCGGCAAGGCCGCCCAGGTCTGGCTCGATGGCGGCAACATCCGAATGGCAAGC
CTGGATTAA

Upstream 100 bases:

>100_bases
ACCAGGATCCCGGCAGAATTTGCCGACCGGATCAGAAACTTAACCCTTCGGTAACCATACCCGCCGTCAATGGTCCGGTA
AGGACTCTTAACGGGCGGAC

Downstream 100 bases:

>100_bases
GGGAGATCGACGCGTGGCAAAGGTTCTCGTCGTCACATCGGGCAAGGGCGGCGTCGGCAAGACGACGACGACCGCGGCCC
TCGGAGCGGCCCTGGCCCAG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSDTLPEPIDPETARAAAPSAPRPLSLRGRAFKALALCPEPPLPEWLAGLDAALKRSPTLLKGRAVILDCAQLKPEPDAL
ETLMNELKARGIAVLGIEGADAVADGLPPLLVKGHPSEKVEIPSVPAEPEPQVVTSITVEGSVRSGQSVINPTGDVTVMG
SVSSGAEILAGGSIHVYGALRGRAIAGAARNPRARIYCRKFEPELLGIDRLVRTAEDMGTALRGKAAQVWLDGGNIRMAS
LD

Sequences:

>Translated_242_residues
MSDTLPEPIDPETARAAAPSAPRPLSLRGRAFKALALCPEPPLPEWLAGLDAALKRSPTLLKGRAVILDCAQLKPEPDAL
ETLMNELKARGIAVLGIEGADAVADGLPPLLVKGHPSEKVEIPSVPAEPEPQVVTSITVEGSVRSGQSVINPTGDVTVMG
SVSSGAEILAGGSIHVYGALRGRAIAGAARNPRARIYCRKFEPELLGIDRLVRTAEDMGTALRGKAAQVWLDGGNIRMAS
LD
>Mature_241_residues
SDTLPEPIDPETARAAAPSAPRPLSLRGRAFKALALCPEPPLPEWLAGLDAALKRSPTLLKGRAVILDCAQLKPEPDALE
TLMNELKARGIAVLGIEGADAVADGLPPLLVKGHPSEKVEIPSVPAEPEPQVVTSITVEGSVRSGQSVINPTGDVTVMGS
VSSGAEILAGGSIHVYGALRGRAIAGAARNPRARIYCRKFEPELLGIDRLVRTAEDMGTALRGKAAQVWLDGGNIRMASL
D

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=220, Percent_Identity=30.4545454545455, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C [H]

EC number: NA

Molecular weight: Translated: 25294; Mature: 25163

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTLPEPIDPETARAAAPSAPRPLSLRGRAFKALALCPEPPLPEWLAGLDAALKRSPTL
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCE
LKGRAVILDCAQLKPEPDALETLMNELKARGIAVLGIEGADAVADGLPPLLVKGHPSEKV
ECCCEEEEEHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHCCCCCEEEECCCCCCE
EIPSVPAEPEPQVVTSITVEGSVRSGQSVINPTGDVTVMGSVSSGAEILAGGSIHVYGAL
ECCCCCCCCCCCEEEEEEEECCCCCCCEEECCCCCEEEEEECCCCCEEEECCCEEEEEEE
RGRAIAGAARNPRARIYCRKFEPELLGIDRLVRTAEDMGTALRGKAAQVWLDGGNIRMAS
CCCEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEE
LD
CC
>Mature Secondary Structure 
SDTLPEPIDPETARAAAPSAPRPLSLRGRAFKALALCPEPPLPEWLAGLDAALKRSPTL
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCE
LKGRAVILDCAQLKPEPDALETLMNELKARGIAVLGIEGADAVADGLPPLLVKGHPSEKV
ECCCEEEEEHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHCCCCCEEEECCCCCCE
EIPSVPAEPEPQVVTSITVEGSVRSGQSVINPTGDVTVMGSVSSGAEILAGGSIHVYGAL
ECCCCCCCCCCCEEEEEEEECCCCCCCEEECCCCCEEEEEECCCCCEEEECCCEEEEEEE
RGRAIAGAARNPRARIYCRKFEPELLGIDRLVRTAEDMGTALRGKAAQVWLDGGNIRMAS
CCCEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEE
LD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA