Click here to switch to the map view.

The map label for this gene is ytxM [H]

Identifier: 170749773

GI number: 170749773

Start: 3579719

End: 3580603

Strand: Reverse

Name: ytxM [H]

Synonym: Mrad2831_3372

Alternate gene names: 170749773

Gene position: 3580603-3579719 (Counterclockwise)

Preceding gene: 170749774

Following gene: 170749770

Centisome position: 58.91

GC content: 72.43

Gene sequence:

>885_bases
ATGCCGAGCGCCACGACGGACGACGGGATACGGCTCCATTACGAGGAGAGCGGCGAGGGGACGCCGCTGATCTTCGTCCA
CGAATTCGCCGGCGACCATCGCAGCTACGAGGCCCAGCTGCGCCATTTCGGCCGCCGCTACCGCGCGGTCGCGTTCAATG
CCCGGGGCTACCCGCCCTCCGACGTGCCGGAGGCCGTCTCGGCCTACGCGCAGGCGCGCGCCGCCGACGACATCCTGGCC
ATCGTCGATCATCTCGGCGCGCCGAAGGCCCACGTCGCCGGCATCTCGATGGGCGCCTTCGCGACCCTGCATTTCGGCCT
GCGGCATCCTGACCGCGCGCTGTCGCTCTGCCTCGGCGGCTGCGGCTACGGCGCGGAGCCCGAGCGGCAGGCCCTGTTCC
GCGCCGAGGCGGACGCCACCGCCGAGATGCTGCGCCGCGACGGCATGGCGGCCTTCGCGGAGCGCTACGCCGTCGGGCCG
ACGCGGGTGCAGTTCGAGACCAAGGACCCGCGCGGGCACGCCGAGTTCAAGCGGATGCTCGCTGAGCACTCGGCCCTCGG
CTCGGCCAACACCCAGGCCGGCGTGCAGAAGGGGCGGCCGTCGCTCTACGACCTCACGGATGAGCTGGGCCGCATGACCG
TCCCGACCCTGATCGTCGCCGGCGACGAGGACTGGCCCTGCCTCGCCCCGAGCCTGATGCTCAAGCGGGTCATCCCCTCC
GCGGCCCTCGCCATGCTGCCCAATACCGGCCACGCCCTCTCGGTCGAGGAGCCCGACGCCTACAACCGGCTCCTCGACGA
CTTCCTGGCGCAGGTGGAGAGCGGCCGCTGGCCGATGCGCGATCCCCGCGCGACCTCGGCGACGATCACCGGGATCAGGG
GCTGA

Upstream 100 bases:

>100_bases
GGCTTCGTCGTGCCCGACACGAAGTCCGGCCTCGGCTCTCGACCGGGTGCCCCGTCGCGCCATCTCGGAGTCCTGGGGGG
TGGTCGGTGAGAGGATCGAC

Downstream 100 bases:

>100_bases
GCGGCTCGCGGGGGATCAGCCGGAACCGGGCCGGCCGGTCCGGCTGGGTCGTGACGACCGCCTGGGGCAGCACCGGCTCG
CGCTCGTCGAGCACCAGCCG

Product: alpha/beta hydrolase fold protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MPSATTDDGIRLHYEESGEGTPLIFVHEFAGDHRSYEAQLRHFGRRYRAVAFNARGYPPSDVPEAVSAYAQARAADDILA
IVDHLGAPKAHVAGISMGAFATLHFGLRHPDRALSLCLGGCGYGAEPERQALFRAEADATAEMLRRDGMAAFAERYAVGP
TRVQFETKDPRGHAEFKRMLAEHSALGSANTQAGVQKGRPSLYDLTDELGRMTVPTLIVAGDEDWPCLAPSLMLKRVIPS
AALAMLPNTGHALSVEEPDAYNRLLDDFLAQVESGRWPMRDPRATSATITGIRG

Sequences:

>Translated_294_residues
MPSATTDDGIRLHYEESGEGTPLIFVHEFAGDHRSYEAQLRHFGRRYRAVAFNARGYPPSDVPEAVSAYAQARAADDILA
IVDHLGAPKAHVAGISMGAFATLHFGLRHPDRALSLCLGGCGYGAEPERQALFRAEADATAEMLRRDGMAAFAERYAVGP
TRVQFETKDPRGHAEFKRMLAEHSALGSANTQAGVQKGRPSLYDLTDELGRMTVPTLIVAGDEDWPCLAPSLMLKRVIPS
AALAMLPNTGHALSVEEPDAYNRLLDDFLAQVESGRWPMRDPRATSATITGIRG
>Mature_293_residues
PSATTDDGIRLHYEESGEGTPLIFVHEFAGDHRSYEAQLRHFGRRYRAVAFNARGYPPSDVPEAVSAYAQARAADDILAI
VDHLGAPKAHVAGISMGAFATLHFGLRHPDRALSLCLGGCGYGAEPERQALFRAEADATAEMLRRDGMAAFAERYAVGPT
RVQFETKDPRGHAEFKRMLAEHSALGSANTQAGVQKGRPSLYDLTDELGRMTVPTLIVAGDEDWPCLAPSLMLKRVIPSA
ALAMLPNTGHALSVEEPDAYNRLLDDFLAQVESGRWPMRDPRATSATITGIRG

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=107, Percent_Identity=36.4485981308411, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI13376164, Length=107, Percent_Identity=36.4485981308411, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR022485 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 31912; Mature: 31781

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSATTDDGIRLHYEESGEGTPLIFVHEFAGDHRSYEAQLRHFGRRYRAVAFNARGYPPS
CCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCC
DVPEAVSAYAQARAADDILAIVDHLGAPKAHVAGISMGAFATLHFGLRHPDRALSLCLGG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCC
CGYGAEPERQALFRAEADATAEMLRRDGMAAFAERYAVGPTRVQFETKDPRGHAEFKRML
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
AEHSALGSANTQAGVQKGRPSLYDLTDELGRMTVPTLIVAGDEDWPCLAPSLMLKRVIPS
HHHHHCCCCCCHHHHHHCCCHHHHHHHHHCCCEECEEEEECCCCCCCCCHHHHHHHHHHH
AALAMLPNTGHALSVEEPDAYNRLLDDFLAQVESGRWPMRDPRATSATITGIRG
HHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure 
PSATTDDGIRLHYEESGEGTPLIFVHEFAGDHRSYEAQLRHFGRRYRAVAFNARGYPPS
CCCCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCC
DVPEAVSAYAQARAADDILAIVDHLGAPKAHVAGISMGAFATLHFGLRHPDRALSLCLGG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCC
CGYGAEPERQALFRAEADATAEMLRRDGMAAFAERYAVGPTRVQFETKDPRGHAEFKRML
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
AEHSALGSANTQAGVQKGRPSLYDLTDELGRMTVPTLIVAGDEDWPCLAPSLMLKRVIPS
HHHHHCCCCCCHHHHHHCCCHHHHHHHHHCCCEECEEEEECCCCCCCCCHHHHHHHHHHH
AALAMLPNTGHALSVEEPDAYNRLLDDFLAQVESGRWPMRDPRATSATITGIRG
HHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8566759; 9387221; 9384377 [H]