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The map label for this gene is yciR [C]

Identifier: 170749699

GI number: 170749699

Start: 3496744

End: 3498525

Strand: Reverse

Name: yciR [C]

Synonym: Mrad2831_3297

Alternate gene names: 170749699

Gene position: 3498525-3496744 (Counterclockwise)

Preceding gene: 170749700

Following gene: 170749695

Centisome position: 57.56

GC content: 70.03

Gene sequence:

>1782_bases
GTGCCGCATACCAGTCTCCGGCGCAGCGAGACTTCGGACAGTTCGCAGTGCGTTCCGGTTCTGCGGCCGAGAGCCGAGGG
CATCGACCGGCTCGCGGCGCTGAACGCGGCCCTCTCGGAGCAGATCCGCCTGTTCGAGGGCGCGCTGCAGAACATGAACC
AGGGCCTGTGCATGTTCGACGCGCAGTCCCGCCTCGTCGTGTCGAACAAGCGCTACCGCGATATCTTCAACATCCCGCAG
GACATGGTCCTCACGGGCATGGCCCAGCACGCGATCTGCTCAGCTCTGGTCGCGCGCGGCCTCTACTCGCCGGAGGTCAC
CGTCGCGGAGATCGAGCGCAGCACCCGCGCCGCCCTTCAGGCCGCCGAGCCCGCGCCGATCACGCGCGAACTCTGCGACG
GGCGCACGCTGGCGATCAATCACCGGGTCATGGACGGCGGCGGCTGGGTCTCGACATTCGAGGACATCACCGAGCAGCGG
CGGAGTGCGGAGCGCATCGCCCACCTGGCCCATCACGACGCCCTGACCGACCTCGCCAACACGCGGGCGATGCGCCAGGG
CTACCGAGATCTGATCGCGGCGCAGGACGACGAGCGACCGCTGCTCGCCATGTATTACATCGACCTCGACCGGTTCAAAT
TCGTCAACGACACCTACGGACATGCCGCCGGCGACGAGCTCCTGCAGGAGGTCGCCGCGCGGCTGCGGAGGAACACGCGG
CGGGGTGACGTCGTGGCCCGCCTCGGCGGCGACGAGTTCGCGCTGGTCCACAGGGTCGTCGACGCGGCCGCCGCGACGTC
GACCGCCCAGCGCCTCGTCAACGTTCTGTCGGAGCCGTTCGATCTCGCGAGCGGGCGCGTCCATACCGGCGCCAGCATCG
GCCTCGCGATCCGCGCGGTGCAGGACCTGGACATGGACCCGTTGCTGCACGACGCCGATCTCGCCCTGCGGCACTCGAAG
ACCGAGGGGCGCGGCGTCTTCAGCGTCTTCGAGGCCAGCATGTCCGAGGCCTTCGAGGCGCGCCGCCAGATCGAGGCCGA
CCTCCAGGCCGCCCTGGCGGCGGATCAGTTCGAGCTGCACTATCAGACCCTCGTCGATGCCCGCGACGGGCATGTCGCCT
GCGTCGAGGCGCTGGTGCGCTGGCGCCATCCCACGCGCGGCCTGGTCCCGCCGCTGTCCTTCATCCCCCTGGCCGAGGAG
ACCGGTCTCATCCTGCCGCTCGGCCGCTGGGTCCTGGAGCGCGCCTGCCGGGATGCCCTGGCGTGGCCCGAGAGCGTCGA
CGTCGCCGTCAACGTCTCCAGCGTCCAGATGCGTCAGAAGGGGTTCGGCGCGGAAGTGCTCGCCGTGCTGGCGGAGACCG
GTCTGGCCGCGGCGCGGCTGGAGGTCGAGATCACCGAGACGTCGCTGCTGGAGGAGAGCGAGGCGACGCGGGAGAATCTC
GCCACGCTCCACGGCGCCGGCATCCGGATCGCCATGGACGATTTCGGCACCGGGTACTCGTCCCTGAGCTATCTGCGCCG
GTTCCCGATCGACAAGATCAAGATCGATCGCTCGTTCATGAGCGAGGCCGAGACGAGCGCCGACGCGCGCGCCATCATCC
GGGCGGTGGCGGGGCTGGGGGTCAGCCTCGGCATCACGACGGTGGTCGAGGGCGTCGAGACGGCGCAGCAGCTGGAACTC
GCGCGGGCCGAGGGTGTCGGGCAGGTTCAGGGCTATCTCCTGGGACGTCCGCAGCCGCAGGCGTCGCTGTCGCGCGCGGG
CCTGCCGACGCATCGATGGTGA

Upstream 100 bases:

>100_bases
CAGACCTGCGCGGCGGCCTCCCGGACGATCGCTTAGCGCGCCCGACCGATCGCGCCGCCCCGCGCGGCTCGGCGCCCCTT
TCCCACTCGAGGACATCATC

Downstream 100 bases:

>100_bases
TCCGATCGGCCATCCGCGGGGCCTCGGACCCGCGTCTCCGTAACGCCACCGGGCCGGAGACGGGTCATCGAGCGGGCGCG
CCGGAGCCGCGCCGCTCAGG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MPHTSLRRSETSDSSQCVPVLRPRAEGIDRLAALNAALSEQIRLFEGALQNMNQGLCMFDAQSRLVVSNKRYRDIFNIPQ
DMVLTGMAQHAICSALVARGLYSPEVTVAEIERSTRAALQAAEPAPITRELCDGRTLAINHRVMDGGGWVSTFEDITEQR
RSAERIAHLAHHDALTDLANTRAMRQGYRDLIAAQDDERPLLAMYYIDLDRFKFVNDTYGHAAGDELLQEVAARLRRNTR
RGDVVARLGGDEFALVHRVVDAAAATSTAQRLVNVLSEPFDLASGRVHTGASIGLAIRAVQDLDMDPLLHDADLALRHSK
TEGRGVFSVFEASMSEAFEARRQIEADLQAALAADQFELHYQTLVDARDGHVACVEALVRWRHPTRGLVPPLSFIPLAEE
TGLILPLGRWVLERACRDALAWPESVDVAVNVSSVQMRQKGFGAEVLAVLAETGLAAARLEVEITETSLLEESEATRENL
ATLHGAGIRIAMDDFGTGYSSLSYLRRFPIDKIKIDRSFMSEAETSADARAIIRAVAGLGVSLGITTVVEGVETAQQLEL
ARAEGVGQVQGYLLGRPQPQASLSRAGLPTHRW

Sequences:

>Translated_593_residues
MPHTSLRRSETSDSSQCVPVLRPRAEGIDRLAALNAALSEQIRLFEGALQNMNQGLCMFDAQSRLVVSNKRYRDIFNIPQ
DMVLTGMAQHAICSALVARGLYSPEVTVAEIERSTRAALQAAEPAPITRELCDGRTLAINHRVMDGGGWVSTFEDITEQR
RSAERIAHLAHHDALTDLANTRAMRQGYRDLIAAQDDERPLLAMYYIDLDRFKFVNDTYGHAAGDELLQEVAARLRRNTR
RGDVVARLGGDEFALVHRVVDAAAATSTAQRLVNVLSEPFDLASGRVHTGASIGLAIRAVQDLDMDPLLHDADLALRHSK
TEGRGVFSVFEASMSEAFEARRQIEADLQAALAADQFELHYQTLVDARDGHVACVEALVRWRHPTRGLVPPLSFIPLAEE
TGLILPLGRWVLERACRDALAWPESVDVAVNVSSVQMRQKGFGAEVLAVLAETGLAAARLEVEITETSLLEESEATRENL
ATLHGAGIRIAMDDFGTGYSSLSYLRRFPIDKIKIDRSFMSEAETSADARAIIRAVAGLGVSLGITTVVEGVETAQQLEL
ARAEGVGQVQGYLLGRPQPQASLSRAGLPTHRW
>Mature_592_residues
PHTSLRRSETSDSSQCVPVLRPRAEGIDRLAALNAALSEQIRLFEGALQNMNQGLCMFDAQSRLVVSNKRYRDIFNIPQD
MVLTGMAQHAICSALVARGLYSPEVTVAEIERSTRAALQAAEPAPITRELCDGRTLAINHRVMDGGGWVSTFEDITEQRR
SAERIAHLAHHDALTDLANTRAMRQGYRDLIAAQDDERPLLAMYYIDLDRFKFVNDTYGHAAGDELLQEVAARLRRNTRR
GDVVARLGGDEFALVHRVVDAAAATSTAQRLVNVLSEPFDLASGRVHTGASIGLAIRAVQDLDMDPLLHDADLALRHSKT
EGRGVFSVFEASMSEAFEARRQIEADLQAALAADQFELHYQTLVDARDGHVACVEALVRWRHPTRGLVPPLSFIPLAEET
GLILPLGRWVLERACRDALAWPESVDVAVNVSSVQMRQKGFGAEVLAVLAETGLAAARLEVEITETSLLEESEATRENLA
TLHGAGIRIAMDDFGTGYSSLSYLRRFPIDKIKIDRSFMSEAETSADARAIIRAVAGLGVSLGITTVVEGVETAQQLELA
RAEGVGQVQGYLLGRPQPQASLSRAGLPTHRW

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=513, Percent_Identity=34.1130604288499, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI87081921, Length=426, Percent_Identity=33.0985915492958, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1788502, Length=334, Percent_Identity=33.8323353293413, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI226510982, Length=412, Percent_Identity=27.6699029126214, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786507, Length=236, Percent_Identity=34.7457627118644, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081845, Length=248, Percent_Identity=35.0806451612903, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081980, Length=243, Percent_Identity=35.8024691358025, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790496, Length=235, Percent_Identity=32.3404255319149, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788381, Length=444, Percent_Identity=26.1261261261261, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787055, Length=272, Percent_Identity=30.8823529411765, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1788849, Length=438, Percent_Identity=26.9406392694064, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=30.5785123966942, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI87082096, Length=203, Percent_Identity=31.5270935960591, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=37.8531073446328, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788956, Length=130, Percent_Identity=40.7692307692308, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081977, Length=170, Percent_Identity=33.5294117647059, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=34.1463414634146, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786584, Length=282, Percent_Identity=26.9503546099291, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787056, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787410, Length=148, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787262, Length=171, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=32.0754716981132, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=27.710843373494, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=27.710843373494, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787816, Length=155, Percent_Identity=29.6774193548387, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 64921; Mature: 64790

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHTSLRRSETSDSSQCVPVLRPRAEGIDRLAALNAALSEQIRLFEGALQNMNQGLCMFD
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AQSRLVVSNKRYRDIFNIPQDMVLTGMAQHAICSALVARGLYSPEVTVAEIERSTRAALQ
CCCCEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AAEPAPITRELCDGRTLAINHRVMDGGGWVSTFEDITEQRRSAERIAHLAHHDALTDLAN
CCCCCCCHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRAMRQGYRDLIAAQDDERPLLAMYYIDLDRFKFVNDTYGHAAGDELLQEVAARLRRNTR
HHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
RGDVVARLGGDEFALVHRVVDAAAATSTAQRLVNVLSEPFDLASGRVHTGASIGLAIRAV
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEECCCHHHHHHHHH
QDLDMDPLLHDADLALRHSKTEGRGVFSVFEASMSEAFEARRQIEADLQAALAADQFELH
HHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQTLVDARDGHVACVEALVRWRHPTRGLVPPLSFIPLAEETGLILPLGRWVLERACRDAL
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCEEEHHHHHHHHHHHHHH
AWPESVDVAVNVSSVQMRQKGFGAEVLAVLAETGLAAARLEVEITETSLLEESEATRENL
CCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHHHHHH
ATLHGAGIRIAMDDFGTGYSSLSYLRRFPIDKIKIDRSFMSEAETSADARAIIRAVAGLG
HHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEECHHHHHHHHCCHHHHHHHHHHHHCC
VSLGITTVVEGVETAQQLELARAEGVGQVQGYLLGRPQPQASLSRAGLPTHRW
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
PHTSLRRSETSDSSQCVPVLRPRAEGIDRLAALNAALSEQIRLFEGALQNMNQGLCMFD
CCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AQSRLVVSNKRYRDIFNIPQDMVLTGMAQHAICSALVARGLYSPEVTVAEIERSTRAALQ
CCCCEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AAEPAPITRELCDGRTLAINHRVMDGGGWVSTFEDITEQRRSAERIAHLAHHDALTDLAN
CCCCCCCHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRAMRQGYRDLIAAQDDERPLLAMYYIDLDRFKFVNDTYGHAAGDELLQEVAARLRRNTR
HHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
RGDVVARLGGDEFALVHRVVDAAAATSTAQRLVNVLSEPFDLASGRVHTGASIGLAIRAV
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEECCCHHHHHHHHH
QDLDMDPLLHDADLALRHSKTEGRGVFSVFEASMSEAFEARRQIEADLQAALAADQFELH
HHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQTLVDARDGHVACVEALVRWRHPTRGLVPPLSFIPLAEETGLILPLGRWVLERACRDAL
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCEEEHHHHHHHHHHHHHH
AWPESVDVAVNVSSVQMRQKGFGAEVLAVLAETGLAAARLEVEITETSLLEESEATRENL
CCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHHHHHH
ATLHGAGIRIAMDDFGTGYSSLSYLRRFPIDKIKIDRSFMSEAETSADARAIIRAVAGLG
HHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEECHHHHHHHHCCHHHHHHHHHHHHCC
VSLGITTVVEGVETAQQLELARAEGVGQVQGYLLGRPQPQASLSRAGLPTHRW
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]