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The map label for this gene is glpD [H]

Identifier: 170749671

GI number: 170749671

Start: 3463393

End: 3464895

Strand: Reverse

Name: glpD [H]

Synonym: Mrad2831_3269

Alternate gene names: 170749671

Gene position: 3464895-3463393 (Counterclockwise)

Preceding gene: 170749672

Following gene: 170749670

Centisome position: 57.01

GC content: 72.26

Gene sequence:

>1503_bases
ATGCGCACGTTCGACGTTGCCGTCATCGGCGGGGGGATCAACGGCTGCGGGATCGCGCGGGACGCGGCCGGCCGCGGATA
CTCGGTCTCGCTGACCGAGCAGAACGACCTCGGCAGCGGCACCTCGTCATGGTCGACCAAACTGATCCACGGCGGCCTGC
GCTACCTGGAGCACTACGAGTTTCGCCTCGTGCGCGAGGCGCTGGCCGAGCGCGAGGTGCTCTGGGGCATCGCGCCCCAC
ATCGTGCGCCCGCTGCGCTTCGTCCTGCCGCTGCATACCGGCCTGCGTCCGGCCTGGCTGCTGCGGATCGGGCTGTTCCT
CTACGACCATCTCGGCGGCCGCAAGCGCCTGCCCGGCACGCGCCCCGTGGATCTCTCCGGCCCGATCGGCGCCCCGCTCA
AATCCGAGTTCCGGCGCGGCTTCGAGTATTCGGACGCGCGCGTCGACGACACGCGGCTCGTGGTGCTCAACGCGCGCGAT
GCCGAGGCGCGGGGCGCCGAGATCGCGGTGGGAACCCGCGTCGTCTCGGTCCGCCGCGAGGGCGATCTGTGGCGCATCGT
CCGGCGCGAGCTGCAGACCGGCCGCGAGGACGAGATCGCCGCGCGCTTCCTCGTGAACGCGGCCGGACCCTGGGTCGACC
GGGTGATCCAGGGGCCGCTCGGCCGGAGCGAGGCGAAGCACGTGCGCCTCGTGCAGGGCTCGCACATCGTGACGCGCAAG
CTCTACGACCACGACCGGGCCTTCATCTTCCAGAACGCGGACGGGCGCATCATCTTCGCGATCCCCTACGCGAACGACAC
GACCCTGGTCGGCACGACGGACCGTGATTTCTCCGGCGATCCCGCCGACGCGGCGATCACCGAGGAGGAGACCGCGTATC
TGCTGAGCGCCGCCAGCGAGTACTTCGCGACGCCGCTGCGCCGCGACGACATCGTCTGGTCCTTCTCGGGCGTGCGCCCC
CTCTACGACGATCACGCCTCCGCGGCGCAGGAGGCGACGCGCGACTACGTGCTGAAGACGGACGGCGCGGCCGGCGAGGC
GGCGGTGCTCAACATCTTCGGCGGAAAGATCACGACCTACCGCAAGCTGGCCGAGGATGCCCTGAAGGAGATCGGTCAGC
GCCTCGGCGCGCGCGGCCGCTCTTGGACCGGAAGCGCCGCGCTGCCGGGCGGCGATTTTCCGGTGGACGGGGTGGCCGAG
CTCGAGGCGCGCCTCGCCCGCGCCGCGCCCCAGCTCGCGGCCGCCACGGTCCAGCGCCTGGTGGCCGCCTACGGGACGGA
CGCGCTGCGCATCGCCGCGAATCTCGGGCCCGACCTCGGGCACGGCCTCCACGAAGGCGAGCTGCGCTGGATGATGGACC
GGGAATGGGCCCGCACCGCCGAGGACGTGCTCTGGCGTCGGTCCAAGCTCGGCCTCGCCTTCTCGGCCGACGAGGTCGCG
GCGCTGCGGGCGAAGATCGCGACCATGACCGGCCGGCACGCCGGCGCGATGGCCGCCGGCTGA

Upstream 100 bases:

>100_bases
TGAGCGTATCGCTTTCGATTGACTTTCCTTTGGTTTCGTATTCAATTCCTCTGCTTTCGCAGTCGCGCGCCGGACGCCGC
GACACGAAAGGGGGAGGATC

Downstream 100 bases:

>100_bases
GCCGGCCGCCCCGCGCGGGCGGCAGGGGAACCGCACGACGGCGACCCGGCCGAGCCGGAGATGCGCCGCACCACAGGGAG
GAAACGATGCCGCGACCGGA

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MRTFDVAVIGGGINGCGIARDAAGRGYSVSLTEQNDLGSGTSSWSTKLIHGGLRYLEHYEFRLVREALAEREVLWGIAPH
IVRPLRFVLPLHTGLRPAWLLRIGLFLYDHLGGRKRLPGTRPVDLSGPIGAPLKSEFRRGFEYSDARVDDTRLVVLNARD
AEARGAEIAVGTRVVSVRREGDLWRIVRRELQTGREDEIAARFLVNAAGPWVDRVIQGPLGRSEAKHVRLVQGSHIVTRK
LYDHDRAFIFQNADGRIIFAIPYANDTTLVGTTDRDFSGDPADAAITEEETAYLLSAASEYFATPLRRDDIVWSFSGVRP
LYDDHASAAQEATRDYVLKTDGAAGEAAVLNIFGGKITTYRKLAEDALKEIGQRLGARGRSWTGSAALPGGDFPVDGVAE
LEARLARAAPQLAAATVQRLVAAYGTDALRIAANLGPDLGHGLHEGELRWMMDREWARTAEDVLWRRSKLGLAFSADEVA
ALRAKIATMTGRHAGAMAAG

Sequences:

>Translated_500_residues
MRTFDVAVIGGGINGCGIARDAAGRGYSVSLTEQNDLGSGTSSWSTKLIHGGLRYLEHYEFRLVREALAEREVLWGIAPH
IVRPLRFVLPLHTGLRPAWLLRIGLFLYDHLGGRKRLPGTRPVDLSGPIGAPLKSEFRRGFEYSDARVDDTRLVVLNARD
AEARGAEIAVGTRVVSVRREGDLWRIVRRELQTGREDEIAARFLVNAAGPWVDRVIQGPLGRSEAKHVRLVQGSHIVTRK
LYDHDRAFIFQNADGRIIFAIPYANDTTLVGTTDRDFSGDPADAAITEEETAYLLSAASEYFATPLRRDDIVWSFSGVRP
LYDDHASAAQEATRDYVLKTDGAAGEAAVLNIFGGKITTYRKLAEDALKEIGQRLGARGRSWTGSAALPGGDFPVDGVAE
LEARLARAAPQLAAATVQRLVAAYGTDALRIAANLGPDLGHGLHEGELRWMMDREWARTAEDVLWRRSKLGLAFSADEVA
ALRAKIATMTGRHAGAMAAG
>Mature_500_residues
MRTFDVAVIGGGINGCGIARDAAGRGYSVSLTEQNDLGSGTSSWSTKLIHGGLRYLEHYEFRLVREALAEREVLWGIAPH
IVRPLRFVLPLHTGLRPAWLLRIGLFLYDHLGGRKRLPGTRPVDLSGPIGAPLKSEFRRGFEYSDARVDDTRLVVLNARD
AEARGAEIAVGTRVVSVRREGDLWRIVRRELQTGREDEIAARFLVNAAGPWVDRVIQGPLGRSEAKHVRLVQGSHIVTRK
LYDHDRAFIFQNADGRIIFAIPYANDTTLVGTTDRDFSGDPADAAITEEETAYLLSAASEYFATPLRRDDIVWSFSGVRP
LYDDHASAAQEATRDYVLKTDGAAGEAAVLNIFGGKITTYRKLAEDALKEIGQRLGARGRSWTGSAALPGGDFPVDGVAE
LEARLARAAPQLAAATVQRLVAAYGTDALRIAANLGPDLGHGLHEGELRWMMDREWARTAEDVLWRRSKLGLAFSADEVA
ALRAKIATMTGRHAGAMAAG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=530, Percent_Identity=32.8301886792453, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI285002231, Length=530, Percent_Identity=32.8301886792453, Blast_Score=186, Evalue=5e-47,
Organism=Escherichia coli, GI2367226, Length=457, Percent_Identity=46.3894967177243, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1788574, Length=488, Percent_Identity=27.8688524590164, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17509253, Length=520, Percent_Identity=29.8076923076923, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI115534726, Length=515, Percent_Identity=29.7087378640777, Blast_Score=152, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6322036, Length=565, Percent_Identity=27.9646017699115, Blast_Score=159, Evalue=8e-40,
Organism=Drosophila melanogaster, GI161077125, Length=509, Percent_Identity=30.0589390962672, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24653942, Length=509, Percent_Identity=30.0589390962672, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24653944, Length=509, Percent_Identity=30.0589390962672, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20130025, Length=509, Percent_Identity=30.0589390962672, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24586295, Length=517, Percent_Identity=29.4003868471954, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19921278, Length=525, Percent_Identity=22.2857142857143, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 54594; Mature: 54594

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTFDVAVIGGGINGCGIARDAAGRGYSVSLTEQNDLGSGTSSWSTKLIHGGLRYLEHYE
CCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
FRLVREALAEREVLWGIAPHIVRPLRFVLPLHTGLRPAWLLRIGLFLYDHLGGRKRLPGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
RPVDLSGPIGAPLKSEFRRGFEYSDARVDDTRLVVLNARDAEARGAEIAVGTRVVSVRRE
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECEEEEEEECC
GDLWRIVRRELQTGREDEIAARFLVNAAGPWVDRVIQGPLGRSEAKHVRLVQGSHIVTRK
CHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEECCCEEEHHH
LYDHDRAFIFQNADGRIIFAIPYANDTTLVGTTDRDFSGDPADAAITEEETAYLLSAASE
HHCCCCEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHH
YFATPLRRDDIVWSFSGVRPLYDDHASAAQEATRDYVLKTDGAAGEAAVLNIFGGKITTY
HHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEECCCCCCCEEEEEECCCCHHHH
RKLAEDALKEIGQRLGARGRSWTGSAALPGGDFPVDGVAELEARLARAAPQLAAATVQRL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHH
VAAYGTDALRIAANLGPDLGHGLHEGELRWMMDREWARTAEDVLWRRSKLGLAFSADEVA
HHHHCCCCEEEEECCCCHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCEEECHHHHH
ALRAKIATMTGRHAGAMAAG
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRTFDVAVIGGGINGCGIARDAAGRGYSVSLTEQNDLGSGTSSWSTKLIHGGLRYLEHYE
CCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
FRLVREALAEREVLWGIAPHIVRPLRFVLPLHTGLRPAWLLRIGLFLYDHLGGRKRLPGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
RPVDLSGPIGAPLKSEFRRGFEYSDARVDDTRLVVLNARDAEARGAEIAVGTRVVSVRRE
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECEEEEEEECC
GDLWRIVRRELQTGREDEIAARFLVNAAGPWVDRVIQGPLGRSEAKHVRLVQGSHIVTRK
CHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEECCCEEEHHH
LYDHDRAFIFQNADGRIIFAIPYANDTTLVGTTDRDFSGDPADAAITEEETAYLLSAASE
HHCCCCEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHH
YFATPLRRDDIVWSFSGVRPLYDDHASAAQEATRDYVLKTDGAAGEAAVLNIFGGKITTY
HHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEECCCCCCCEEEEEECCCCHHHH
RKLAEDALKEIGQRLGARGRSWTGSAALPGGDFPVDGVAELEARLARAAPQLAAATVQRL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHH
VAAYGTDALRIAANLGPDLGHGLHEGELRWMMDREWARTAEDVLWRRSKLGLAFSADEVA
HHHHCCCCEEEEECCCCHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCEEECHHHHH
ALRAKIATMTGRHAGAMAAG
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]