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The map label for this gene is glpT [H]

Identifier: 170749670

GI number: 170749670

Start: 3461782

End: 3463122

Strand: Reverse

Name: glpT [H]

Synonym: Mrad2831_3268

Alternate gene names: 170749670

Gene position: 3463122-3461782 (Counterclockwise)

Preceding gene: 170749671

Following gene: 170749661

Centisome position: 56.98

GC content: 66.74

Gene sequence:

>1341_bases
ATGATCGGCTTCCTCGCTCCCGCGGCCCATCGGCCACCCATTCAGACGGATCGCGTCGATCCGACCTACCGCAAGCTGCG
TTGGCAGATCTTCGCGGGAATCTTCCTGGGCTATGCGGGCTATTACCTGCTGCGCAAGAACTTCTCGCTGGCCATGCCCT
ACTTGGTCGAGCAGGGCTACAGCCGCGGTGAGCTCGGCACTGCGCTCTCCGCGGTGGCGATCGCGTACGGCCTGTCCAAG
TTCCTGATGGGCATGGTCTCGGACCGCTCCAACCCGCGCTACTTCCTGCCGATCGGCCTCGTGCTCTCGGCGCTGGTGAT
GTTCCTGTTCGGCTTCGTGCCCTGGGCGACGTCCAGCGTCGGCATCATGTTCGTGCTGCTCTTCCTCAACGGCTGGTTCC
AGGGCATGGGCTGGCCGCCGAGCGGTCGCACGATGGTGCACTGGTGGTCGCAGAAGGAGCGCGGCGGCGTCGTCTCGGTC
TGGAACGTGGCGCACAACGTCGGCGGTGGCCTGATCGGGCCGCTGTTCCTGCTCGGCCTGGCCTGGTTCAACGACTGGCA
CGCGGCCTTCTACGTGCCCGCCGCCGTGGCGCTCGGCGTCGCGGTCTTCGCCTTCCTGACCATGCGGGACACGCCGCAAT
CCTGCGGGCTGCCGTCCGTGGAGACCTGGAAGAACGATTACCCGGAGGGCTACGACGCCAACCACGAGCGCGAGTTCTCC
ACGCGCGAGATCTTCGTCGAGCACGTCCTGAAGAACCGGATGCTCTGGTACATCGCCTTCGCCAACGTGTTCGTCTACCT
GCTCCGCTACGGTGTGCTGGACTGGGCGCCGACCTACCTGAAGGAGGCCAAGCACTTCTCGGTGGACAAGACCTCCTGGG
CCTACTTCCTCTACGAGTGGGCCGGCATCCCCGGCACCCTGCTCTGCGGCTGGCTGTCCGACAAACTGTTCCGCGGCAAT
CGCGGCGCGACGGGCGTGGTGTTCATGTTCGGCGTCATGGCGGCGACGCTGGTCTACTGGCTCAACCCCGAGGGCAACCC
GGGCGTCGATCTCGCGGCCCTGATCTGCATCGGCTTCCTGATCTACGGGCCGGTGATGCTGATCGGTCTCCAGGCCCTCG
AGCTCGTGCCCAAGAAGGCGGCCGGGACGGCGGCGGGCTTCACGGGCCTGTTCGGGTATCTGGGGGGCTCCGTCGCGGCG
AGCGCGCTGGTCGGCTACACGACCGACCATTACGGCTGGAACGGTTGCTTCATCCTCCTGCTGGCGGCCTGCGTCCTCGC
GATCGTCTGCCTGGCCCTGACCCTGCGGCACACCGGCACCGCGGCCCCGCAATTCGCCTGA

Upstream 100 bases:

>100_bases
GCTTCGGCGCGACGCTGAGCGCGGCCCGTCACCACCCCGTCCAATCCGAGATGCGCCCGGGATGAGCCTGGGTCCGTCCG
CGATCTCACGAAGGCGCGCC

Downstream 100 bases:

>100_bases
CCGCCGGTCCTGTCGGCGCGGCAGGGAGGCTGAAGCCCCCCTGCCGATCCCGTGCCGGCGGATCAGGCCGGAGCGCCCAG
AGCGGCCGACTGGCCCGCGC

Product: sn-glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MIGFLAPAAHRPPIQTDRVDPTYRKLRWQIFAGIFLGYAGYYLLRKNFSLAMPYLVEQGYSRGELGTALSAVAIAYGLSK
FLMGMVSDRSNPRYFLPIGLVLSALVMFLFGFVPWATSSVGIMFVLLFLNGWFQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLLGLAWFNDWHAAFYVPAAVALGVAVFAFLTMRDTPQSCGLPSVETWKNDYPEGYDANHEREFS
TREIFVEHVLKNRMLWYIAFANVFVYLLRYGVLDWAPTYLKEAKHFSVDKTSWAYFLYEWAGIPGTLLCGWLSDKLFRGN
RGATGVVFMFGVMAATLVYWLNPEGNPGVDLAALICIGFLIYGPVMLIGLQALELVPKKAAGTAAGFTGLFGYLGGSVAA
SALVGYTTDHYGWNGCFILLLAACVLAIVCLALTLRHTGTAAPQFA

Sequences:

>Translated_446_residues
MIGFLAPAAHRPPIQTDRVDPTYRKLRWQIFAGIFLGYAGYYLLRKNFSLAMPYLVEQGYSRGELGTALSAVAIAYGLSK
FLMGMVSDRSNPRYFLPIGLVLSALVMFLFGFVPWATSSVGIMFVLLFLNGWFQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLLGLAWFNDWHAAFYVPAAVALGVAVFAFLTMRDTPQSCGLPSVETWKNDYPEGYDANHEREFS
TREIFVEHVLKNRMLWYIAFANVFVYLLRYGVLDWAPTYLKEAKHFSVDKTSWAYFLYEWAGIPGTLLCGWLSDKLFRGN
RGATGVVFMFGVMAATLVYWLNPEGNPGVDLAALICIGFLIYGPVMLIGLQALELVPKKAAGTAAGFTGLFGYLGGSVAA
SALVGYTTDHYGWNGCFILLLAACVLAIVCLALTLRHTGTAAPQFA
>Mature_446_residues
MIGFLAPAAHRPPIQTDRVDPTYRKLRWQIFAGIFLGYAGYYLLRKNFSLAMPYLVEQGYSRGELGTALSAVAIAYGLSK
FLMGMVSDRSNPRYFLPIGLVLSALVMFLFGFVPWATSSVGIMFVLLFLNGWFQGMGWPPSGRTMVHWWSQKERGGVVSV
WNVAHNVGGGLIGPLFLLGLAWFNDWHAAFYVPAAVALGVAVFAFLTMRDTPQSCGLPSVETWKNDYPEGYDANHEREFS
TREIFVEHVLKNRMLWYIAFANVFVYLLRYGVLDWAPTYLKEAKHFSVDKTSWAYFLYEWAGIPGTLLCGWLSDKLFRGN
RGATGVVFMFGVMAATLVYWLNPEGNPGVDLAALICIGFLIYGPVMLIGLQALELVPKKAAGTAAGFTGLFGYLGGSVAA
SALVGYTTDHYGWNGCFILLLAACVLAIVCLALTLRHTGTAAPQFA

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=423, Percent_Identity=28.3687943262411, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI4503847, Length=423, Percent_Identity=28.3687943262411, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI256219483, Length=423, Percent_Identity=28.3687943262411, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI256219543, Length=445, Percent_Identity=28.0898876404494, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI38093649, Length=399, Percent_Identity=26.8170426065163, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI223717983, Length=399, Percent_Identity=26.8170426065163, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI256219564, Length=337, Percent_Identity=25.8160237388724, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI46361976, Length=400, Percent_Identity=25, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI49619231, Length=420, Percent_Identity=24.2857142857143, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI14150047, Length=163, Percent_Identity=30.6748466257669, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788573, Length=435, Percent_Identity=70.5747126436782, Blast_Score=658, Evalue=0.0,
Organism=Escherichia coli, GI87082310, Length=435, Percent_Identity=38.1609195402299, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI2367259, Length=420, Percent_Identity=34.2857142857143, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1789515, Length=436, Percent_Identity=24.5412844036697, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=22.5581395348837, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI2367379, Length=362, Percent_Identity=25.414364640884, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789152, Length=436, Percent_Identity=22.9357798165138, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI2367193, Length=407, Percent_Identity=24.0786240786241, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI133901854, Length=437, Percent_Identity=24.4851258581236, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI133901856, Length=437, Percent_Identity=24.4851258581236, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI133930953, Length=473, Percent_Identity=21.3530655391121, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17564204, Length=371, Percent_Identity=25.3369272237197, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564202, Length=439, Percent_Identity=24.1457858769932, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17542316, Length=438, Percent_Identity=22.6027397260274, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24656861, Length=465, Percent_Identity=22.1505376344086, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24656866, Length=465, Percent_Identity=22.1505376344086, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550478, Length=465, Percent_Identity=22.1505376344086, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49177; Mature: 49177

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3329281; 9205837; 9278503; 3141744; 12893936 [H]