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The map label for this gene is siaT [H]

Identifier: 170749669

GI number: 170749669

Start: 3459818

End: 3461101

Strand: Direct

Name: siaT [H]

Synonym: Mrad2831_3266

Alternate gene names: 170749669

Gene position: 3459818-3461101 (Clockwise)

Preceding gene: 170749668

Following gene: 170749673

Centisome position: 56.93

GC content: 66.9

Gene sequence:

>1284_bases
ATGAGCGGCCTGATCATCTTCGGGCTGCTCATCGCCCTCATGCTCACCGGCATGCCGATCTCGATCGCGCTCGGCCTGAC
GGTGCTGACCTTCCTGTTCACGCTGACGCAGGTGCCGATCGAGAGCGTCGCGCTCAAGCTGTTCACCGGGATCGAGAACT
TCTCGATCATGGCGATCCCGTTCTTCATCCTCGCCGGCAACTTCCTGGCCCATGGCGGCGTGGCGCGGCGGATGATCGCC
TTCACGACCTCGCTCGTCGGGCACTGGCCGGGCGGCCTCGGCCTCGCGGGCGTGGTCGCCTGCGCGCTGTTCGCCGCCGT
GTCGGGATCGAGCGTGGCGACGGTCGTGGCGATCGGCTCGATCATCCTGCCGGCCATGGTGGCCGAGGGCTACCCGCGGC
GCTTCGGCGCCGGGGTGATCACCACGTCGGGGGCGCTCGGCATCCTCGTGCCGCCCTCGATCATCCTCGTGCTCTACGGG
GTGTCGACGAATTCCTCAATCGGCAACCTGTTCCTGGCCGGGGTGATGCCCGGCATCGTCCTGTCGGCGATGCTGGCGAC
CGTCACCTTCGTCATCGCCAAGCGCCGGGGCTATCCGCGCATGCCCAGGGCCTCCTGGGCCGAGCGCCTGCGCGCCTTCC
GCGAGAGCGCCTGGGGCCTGTTCCTCGTGGTGATGGTGATCGGCGGCATCTACGCGGGCATCTTCACGCCGACCGAGGCG
GCGGCGACCGCCGCCGTCTACGCCTTCGTCATCGCGGTGTTCGTCTACCGCGACCTGAAGCTGTCGGACGTGCCTCGGGT
GCTCCTCGCCTCCGCCAACATGAGCGCGATGCTGCTCTACATCATCACCAACGCGGTGCTGTTCTCGTTCCTGATGACCT
CCGAGAACATCCCGCAGACGATGGCGGCGTGGCTGATCGCCATGAACTTCAGCCCGCTGGTCTTCCTGCTCGTCGTCAAC
ATCATCCTGCTGATCGCCGGCAACGTGATGGAGCCGTCCTCGATCCTGCTGATCATGGCGCCGATCCTGTTCCCGATCGC
CGTCAAGCTCGGGATCGATCCGATCCATTTCGGGATCATCATGGCGGTCAACATGGAGGTCGGCCTGTGCCACCCGCCGG
TCGGGCTCAACCTCTACGTGGCCAGCGGCATCGCCCATATGGGCATCTCCGAGCTGACGGTGGCGGTGCTGCCCTGGCTC
CTGACGATGCTGGCCTTCCTGGTCCTGGTGACCTACTGGCCGGCCCTCTCCCTGTGGCTCCCGCGGGCGCTCGGGGCGAT
GTGA

Upstream 100 bases:

>100_bases
CGACCGGGCACCTGCCCGCGCGCGACCACGCCCATGTCGACGGCGTCCCGACCGTCGAGGGCGTCGACCCGGTCCAGCTC
GGCCGCGAGGGAGGCCCCGC

Downstream 100 bases:

>100_bases
CGGGCGCGCGCCGCGCGGGTGCAGCCCAGGGCTCGGCCGGCGTTGCGGCGCCCGGGGCACGCGCAGATCGACGCGCGCCA
CCGGCCCCGCCCGCTCGGCA

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSGLIIFGLLIALMLTGMPISIALGLTVLTFLFTLTQVPIESVALKLFTGIENFSIMAIPFFILAGNFLAHGGVARRMIA
FTTSLVGHWPGGLGLAGVVACALFAAVSGSSVATVVAIGSIILPAMVAEGYPRRFGAGVITTSGALGILVPPSIILVLYG
VSTNSSIGNLFLAGVMPGIVLSAMLATVTFVIAKRRGYPRMPRASWAERLRAFRESAWGLFLVVMVIGGIYAGIFTPTEA
AATAAVYAFVIAVFVYRDLKLSDVPRVLLASANMSAMLLYIITNAVLFSFLMTSENIPQTMAAWLIAMNFSPLVFLLVVN
IILLIAGNVMEPSSILLIMAPILFPIAVKLGIDPIHFGIIMAVNMEVGLCHPPVGLNLYVASGIAHMGISELTVAVLPWL
LTMLAFLVLVTYWPALSLWLPRALGAM

Sequences:

>Translated_427_residues
MSGLIIFGLLIALMLTGMPISIALGLTVLTFLFTLTQVPIESVALKLFTGIENFSIMAIPFFILAGNFLAHGGVARRMIA
FTTSLVGHWPGGLGLAGVVACALFAAVSGSSVATVVAIGSIILPAMVAEGYPRRFGAGVITTSGALGILVPPSIILVLYG
VSTNSSIGNLFLAGVMPGIVLSAMLATVTFVIAKRRGYPRMPRASWAERLRAFRESAWGLFLVVMVIGGIYAGIFTPTEA
AATAAVYAFVIAVFVYRDLKLSDVPRVLLASANMSAMLLYIITNAVLFSFLMTSENIPQTMAAWLIAMNFSPLVFLLVVN
IILLIAGNVMEPSSILLIMAPILFPIAVKLGIDPIHFGIIMAVNMEVGLCHPPVGLNLYVASGIAHMGISELTVAVLPWL
LTMLAFLVLVTYWPALSLWLPRALGAM
>Mature_426_residues
SGLIIFGLLIALMLTGMPISIALGLTVLTFLFTLTQVPIESVALKLFTGIENFSIMAIPFFILAGNFLAHGGVARRMIAF
TTSLVGHWPGGLGLAGVVACALFAAVSGSSVATVVAIGSIILPAMVAEGYPRRFGAGVITTSGALGILVPPSIILVLYGV
STNSSIGNLFLAGVMPGIVLSAMLATVTFVIAKRRGYPRMPRASWAERLRAFRESAWGLFLVVMVIGGIYAGIFTPTEAA
ATAAVYAFVIAVFVYRDLKLSDVPRVLLASANMSAMLLYIITNAVLFSFLMTSENIPQTMAAWLIAMNFSPLVFLLVVNI
ILLIAGNVMEPSSILLIMAPILFPIAVKLGIDPIHFGIIMAVNMEVGLCHPPVGLNLYVASGIAHMGISELTVAVLPWLL
TMLAFLVLVTYWPALSLWLPRALGAM

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=398, Percent_Identity=36.1809045226131, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45214; Mature: 45082

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLIIFGLLIALMLTGMPISIALGLTVLTFLFTLTQVPIESVALKLFTGIENFSIMAIP
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHH
FFILAGNFLAHGGVARRMIAFTTSLVGHWPGGLGLAGVVACALFAAVSGSSVATVVAIGS
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
IILPAMVAEGYPRRFGAGVITTSGALGILVPPSIILVLYGVSTNSSIGNLFLAGVMPGIV
HHHHHHHHCCCCCHHCCCEEECCCCCEEECCCHHEEEEECCCCCCCHHHHHHHHHHHHHH
LSAMLATVTFVIAKRRGYPRMPRASWAERLRAFRESAWGLFLVVMVIGGIYAGIFTPTEA
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AATAAVYAFVIAVFVYRDLKLSDVPRVLLASANMSAMLLYIITNAVLFSFLMTSENIPQT
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
MAAWLIAMNFSPLVFLLVVNIILLIAGNVMEPSSILLIMAPILFPIAVKLGIDPIHFGII
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHEE
MAVNMEVGLCHPPVGLNLYVASGIAHMGISELTVAVLPWLLTMLAFLVLVTYWPALSLWL
EEEECEEECCCCCCCCEEHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PRALGAM
HHHHCCC
>Mature Secondary Structure 
SGLIIFGLLIALMLTGMPISIALGLTVLTFLFTLTQVPIESVALKLFTGIENFSIMAIP
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHH
FFILAGNFLAHGGVARRMIAFTTSLVGHWPGGLGLAGVVACALFAAVSGSSVATVVAIGS
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
IILPAMVAEGYPRRFGAGVITTSGALGILVPPSIILVLYGVSTNSSIGNLFLAGVMPGIV
HHHHHHHHCCCCCHHCCCEEECCCCCEEECCCHHEEEEECCCCCCCHHHHHHHHHHHHHH
LSAMLATVTFVIAKRRGYPRMPRASWAERLRAFRESAWGLFLVVMVIGGIYAGIFTPTEA
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AATAAVYAFVIAVFVYRDLKLSDVPRVLLASANMSAMLLYIITNAVLFSFLMTSENIPQT
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
MAAWLIAMNFSPLVFLLVVNIILLIAGNVMEPSSILLIMAPILFPIAVKLGIDPIHFGII
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHEE
MAVNMEVGLCHPPVGLNLYVASGIAHMGISELTVAVLPWLLTMLAFLVLVTYWPALSLWL
EEEECEEECCCCCCCCEEHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PRALGAM
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]