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The map label for this gene is potC [H]

Identifier: 170749633

GI number: 170749633

Start: 3417558

End: 3418376

Strand: Reverse

Name: potC [H]

Synonym: Mrad2831_3230

Alternate gene names: 170749633

Gene position: 3418376-3417558 (Counterclockwise)

Preceding gene: 170749634

Following gene: 170749632

Centisome position: 56.24

GC content: 69.35

Gene sequence:

>819_bases
ATGCGCCGCGGCCTCCGCACCCGGCTTCTCGGGATCTCCGGCAGGGTCCTCGTCGGGCTGATCCTCGCCTTCATCGTGCT
GCCGGCCTTCGTGGTGACGCTCGCCGCGTTCAACGACCGGGCGATCCTGAGCTTCCCGCCGGCCAAGTACTCGACGCGCT
GGTTCACCCGGGCCCTGACCTACCGGGATTTCCAGACGGGCCTGTGGAACAGCCTCGTCGTCACCGCCTGGGCCTCCACG
CTCGCGCTCGCCGTGGGCACCGGCTTCGCGATCGCCCTGAAGCGATACGCTTTCCGCTTCAAGGCGGCGCTGGAGGGCGT
GCTGCTCTCGCCGCTGATCGTGCCGCACTTCACCATCGGCCTCGGCCTCCTGGTCCTGGCCACCGGCATCGGTGCGGCGC
GGGGCTTCTCCGTCGTGGTCCTCACCCACGTCGTGGTGGTGCTGCCCTTCGTGATCCGCTCGGTCTACATCTCGCTGCAG
AACATCGACGAGCGGCTGGAGCTGGCCGCCGCGAGCCTCGGCGCCCGGCCGGGCCGCGTGCTCACCACCGTGACCCTGCC
GCTCCTCGCGCCCGGCCTCGCCAGCGGCTGGCTGTTCGCGGCGATCCTGTCCTTCAACGAGTTCACCGCCTCGCTCTTCG
TGACGGGGCAGGCGACCCAGACCCTGCCGGTGGCGATGTACGGCTACGTCCGCGAGTTCGCGGACCCGACGCTCGCGGCC
GTCTCGGTGATCTACATCGCGGTCACGGCCCTCGCCCTGATTGTCGCCAACACGTTCCTCGGGCTCGGCAAGGTTCTGAA
TGTTGAGCAAGGCTCTTGA

Upstream 100 bases:

>100_bases
TCGCGGCGTCCCTGAGCCTCGCCGGCCTCGTCCTGGCGCTCGGAACGATGTGGCTCGTGCGCCGCTGCGCCCGCCCGCTC
GAAGCGCTCGGAGGCCACTG

Downstream 100 bases:

>100_bases
TCTCACCGCGGCGGGACCCCGGCCCGCCACGGCCGCGGCGCCCCGGGCAAGACCGGCGGTCCGCCTCGACGGCGTGGTCA
AGCGCTTCGGCGCGGTCACC

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MRRGLRTRLLGISGRVLVGLILAFIVLPAFVVTLAAFNDRAILSFPPAKYSTRWFTRALTYRDFQTGLWNSLVVTAWAST
LALAVGTGFAIALKRYAFRFKAALEGVLLSPLIVPHFTIGLGLLVLATGIGAARGFSVVVLTHVVVVLPFVIRSVYISLQ
NIDERLELAAASLGARPGRVLTTVTLPLLAPGLASGWLFAAILSFNEFTASLFVTGQATQTLPVAMYGYVREFADPTLAA
VSVIYIAVTALALIVANTFLGLGKVLNVEQGS

Sequences:

>Translated_272_residues
MRRGLRTRLLGISGRVLVGLILAFIVLPAFVVTLAAFNDRAILSFPPAKYSTRWFTRALTYRDFQTGLWNSLVVTAWAST
LALAVGTGFAIALKRYAFRFKAALEGVLLSPLIVPHFTIGLGLLVLATGIGAARGFSVVVLTHVVVVLPFVIRSVYISLQ
NIDERLELAAASLGARPGRVLTTVTLPLLAPGLASGWLFAAILSFNEFTASLFVTGQATQTLPVAMYGYVREFADPTLAA
VSVIYIAVTALALIVANTFLGLGKVLNVEQGS
>Mature_272_residues
MRRGLRTRLLGISGRVLVGLILAFIVLPAFVVTLAAFNDRAILSFPPAKYSTRWFTRALTYRDFQTGLWNSLVVTAWAST
LALAVGTGFAIALKRYAFRFKAALEGVLLSPLIVPHFTIGLGLLVLATGIGAARGFSVVVLTHVVVVLPFVIRSVYISLQ
NIDERLELAAASLGARPGRVLTTVTLPLLAPGLASGWLFAAILSFNEFTASLFVTGQATQTLPVAMYGYVREFADPTLAA
VSVIYIAVTALALIVANTFLGLGKVLNVEQGS

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=215, Percent_Identity=30.6976744186047, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787081, Length=228, Percent_Identity=30.7017543859649, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787714, Length=235, Percent_Identity=31.4893617021277, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786980, Length=204, Percent_Identity=33.8235294117647, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29053; Mature: 29053

Theoretical pI: Translated: 11.17; Mature: 11.17

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRGLRTRLLGISGRVLVGLILAFIVLPAFVVTLAAFNDRAILSFPPAKYSTRWFTRALT
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHH
YRDFQTGLWNSLVVTAWASTLALAVGTGFAIALKRYAFRFKAALEGVLLSPLIVPHFTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLLVLATGIGAARGFSVVVLTHVVVVLPFVIRSVYISLQNIDERLELAAASLGARPGRV
HHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LTTVTLPLLAPGLASGWLFAAILSFNEFTASLFVTGQATQTLPVAMYGYVREFADPTLAA
HHEEEHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHCCHHHHH
VSVIYIAVTALALIVANTFLGLGKVLNVEQGS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRRGLRTRLLGISGRVLVGLILAFIVLPAFVVTLAAFNDRAILSFPPAKYSTRWFTRALT
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHH
YRDFQTGLWNSLVVTAWASTLALAVGTGFAIALKRYAFRFKAALEGVLLSPLIVPHFTIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLLVLATGIGAARGFSVVVLTHVVVVLPFVIRSVYISLQNIDERLELAAASLGARPGRV
HHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LTTVTLPLLAPGLASGWLFAAILSFNEFTASLFVTGQATQTLPVAMYGYVREFADPTLAA
HHEEEHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHCCHHHHH
VSVIYIAVTALALIVANTFLGLGKVLNVEQGS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]