Click here to switch to the map view.

The map label for this gene is oxyR [H]

Identifier: 170749628

GI number: 170749628

Start: 3413364

End: 3414311

Strand: Reverse

Name: oxyR [H]

Synonym: Mrad2831_3225

Alternate gene names: 170749628

Gene position: 3414311-3413364 (Counterclockwise)

Preceding gene: 170749629

Following gene: 170749627

Centisome position: 56.18

GC content: 70.57

Gene sequence:

>948_bases
ATGCGGTTCACCCTGCGCCAGCTCGAATACTTCATCGCCGCCGGCCAGACCGGCAGCATCACGCTCGCTTCCGAGCGCAT
CCACATCTCGCAGCCCTCGATCTCGACGGCCATCGCGCATCTGGAGCGGGAACTCTCCGTGCAGCTCTTCGTCCGTCACC
ACGCGCAGGGGCTCACGCTGACGCCGATCGGCCGCGAGGTGCTGCGCGAAGCCAAGGCCCTCGTGGAGCAGGCCGAAGGC
CTCTACACCCTGGCGTCCGAGGCGGGGGGACAGGTGCGGGGCCCCCTCTCGCTCGGCTGCATGGTGACGCTCGCGCCGAT
GCTGGTGCCCGAACTCGCCCACGCCTTCACCACCGCCTTCCCGGCCACGCAGATCCGCTACGTCGAGGGCGACCAGGAAC
AGCTCATCGTCGGCCTGCGCCGCTCCGAGACCGAGGTCGTGCTGACCTACGACCTGCACGTGCCGGACGACATCCACTTC
ACCCCGCTCGTCGACCTGCCGCCGCACGTCCTGGTGGCGGAGGGGCACCCGCTGGCGGAGCAGGCCGCCGTCGCGATGAC
CGACATCGTGGACGAGCCGATGATCCTGCTCGACCTGCCGCTGAGCCGCGAATACTTCCTCGCCCTGTTCATGGCCGAGG
GCCTGCAGCCGAAGATCGCCGCGCGCTCCGCCCACCAGGAGGTGGTGCGCACGATGGTGGCCAACGGCCACGGCTACACC
CTGTTCAACGTGCGCCCGCGCTCCGACCTCGCGCTCGACGGGAAGCGGCTCCGGCGGGTGCGGCTCGCCGGCACGCATCG
CCCGATGCGCATCGGCCTCGCGCGCCTGAAGCAGCTCAACCGCTCGCGCCTCGTGGAGGCCTTCGAGACCCATTGCCGGG
CCTTCATCTCGGACGCCTACATCCCCGGCATGGTCGCGCCCGCCATCGAGCGGCGGGTGCCGCGCTGA

Upstream 100 bases:

>100_bases
CGGTCTCCGCCCCGAGCTACGGAGTCCCGGGCGACCTATGATCGAGGACGGGACGCGAGGCGGCATCGAGGTCGGGCCGG
CCGCTCGCTGAAGGCAGCGA

Downstream 100 bases:

>100_bases
AGCCCAGCCCGGCGCGGCGAGCCCCTGAGGAACGCCCGAGGAAAGACCCGAGGAAAGCTCCATGACCGCGCCGATCCCGA
TCCTCTTCCTGAACGGCCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MRFTLRQLEYFIAAGQTGSITLASERIHISQPSISTAIAHLERELSVQLFVRHHAQGLTLTPIGREVLREAKALVEQAEG
LYTLASEAGGQVRGPLSLGCMVTLAPMLVPELAHAFTTAFPATQIRYVEGDQEQLIVGLRRSETEVVLTYDLHVPDDIHF
TPLVDLPPHVLVAEGHPLAEQAAVAMTDIVDEPMILLDLPLSREYFLALFMAEGLQPKIAARSAHQEVVRTMVANGHGYT
LFNVRPRSDLALDGKRLRRVRLAGTHRPMRIGLARLKQLNRSRLVEAFETHCRAFISDAYIPGMVAPAIERRVPR

Sequences:

>Translated_315_residues
MRFTLRQLEYFIAAGQTGSITLASERIHISQPSISTAIAHLERELSVQLFVRHHAQGLTLTPIGREVLREAKALVEQAEG
LYTLASEAGGQVRGPLSLGCMVTLAPMLVPELAHAFTTAFPATQIRYVEGDQEQLIVGLRRSETEVVLTYDLHVPDDIHF
TPLVDLPPHVLVAEGHPLAEQAAVAMTDIVDEPMILLDLPLSREYFLALFMAEGLQPKIAARSAHQEVVRTMVANGHGYT
LFNVRPRSDLALDGKRLRRVRLAGTHRPMRIGLARLKQLNRSRLVEAFETHCRAFISDAYIPGMVAPAIERRVPR
>Mature_315_residues
MRFTLRQLEYFIAAGQTGSITLASERIHISQPSISTAIAHLERELSVQLFVRHHAQGLTLTPIGREVLREAKALVEQAEG
LYTLASEAGGQVRGPLSLGCMVTLAPMLVPELAHAFTTAFPATQIRYVEGDQEQLIVGLRRSETEVVLTYDLHVPDDIHF
TPLVDLPPHVLVAEGHPLAEQAAVAMTDIVDEPMILLDLPLSREYFLALFMAEGLQPKIAARSAHQEVVRTMVANGHGYT
LFNVRPRSDLALDGKRLRRVRLAGTHRPMRIGLARLKQLNRSRLVEAFETHCRAFISDAYIPGMVAPAIERRVPR

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=247, Percent_Identity=29.5546558704453, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787530, Length=237, Percent_Identity=24.0506329113924, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=195, Percent_Identity=25.6410256410256, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789204, Length=301, Percent_Identity=28.2392026578073, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI157672245, Length=218, Percent_Identity=30.2752293577982, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788887, Length=242, Percent_Identity=30.1652892561983, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=175, Percent_Identity=28, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788296, Length=232, Percent_Identity=25.4310344827586, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790262, Length=218, Percent_Identity=23.8532110091743, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787806, Length=138, Percent_Identity=32.6086956521739, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=200, Percent_Identity=23.5, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34962; Mature: 34962

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTLRQLEYFIAAGQTGSITLASERIHISQPSISTAIAHLERELSVQLFVRHHAQGLTL
CCCHHHHHHHHHCCCCCCCEEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
TPIGREVLREAKALVEQAEGLYTLASEAGGQVRGPLSLGCMVTLAPMLVPELAHAFTTAF
CCCCHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PATQIRYVEGDQEQLIVGLRRSETEVVLTYDLHVPDDIHFTPLVDLPPHVLVAEGHPLAE
CCCEEEEEECCHHHEEEEEECCCCEEEEEEEECCCCCCCEEEECCCCCCEEEECCCCCHH
QAAVAMTDIVDEPMILLDLPLSREYFLALFMAEGLQPKIAARSAHQEVVRTMVANGHGYT
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LFNVRPRSDLALDGKRLRRVRLAGTHRPMRIGLARLKQLNRSRLVEAFETHCRAFISDAY
EEEECCCCCCCCCHHHHHEEHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPGMVAPAIERRVPR
CCCHHHHHHHHCCCC
>Mature Secondary Structure
MRFTLRQLEYFIAAGQTGSITLASERIHISQPSISTAIAHLERELSVQLFVRHHAQGLTL
CCCHHHHHHHHHCCCCCCCEEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
TPIGREVLREAKALVEQAEGLYTLASEAGGQVRGPLSLGCMVTLAPMLVPELAHAFTTAF
CCCCHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PATQIRYVEGDQEQLIVGLRRSETEVVLTYDLHVPDDIHFTPLVDLPPHVLVAEGHPLAE
CCCEEEEEECCHHHEEEEEECCCCEEEEEEEECCCCCCCEEEECCCCCCEEEECCCCCHH
QAAVAMTDIVDEPMILLDLPLSREYFLALFMAEGLQPKIAARSAHQEVVRTMVANGHGYT
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LFNVRPRSDLALDGKRLRRVRLAGTHRPMRIGLARLKQLNRSRLVEAFETHCRAFISDAY
EEEECCCCCCCCCHHHHHEEHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPGMVAPAIERRVPR
CCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA