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The map label for this gene is cph2 [H]

Identifier: 170749579

GI number: 170749579

Start: 3352040

End: 3353632

Strand: Reverse

Name: cph2 [H]

Synonym: Mrad2831_3174

Alternate gene names: 170749579

Gene position: 3353632-3352040 (Counterclockwise)

Preceding gene: 170749580

Following gene: 170749577

Centisome position: 55.18

GC content: 72.13

Gene sequence:

>1593_bases
GTGAACCGCAATGACGCGGCCGGCGGCAGCCCGAACGAGTCCATGCTCCTGCGCGCGACCGCCACAGCGATCCGAGCCCA
TCTCGACGATCGCGCCTCGCGCCTGATCGCGGTGGGCGGCACGTGCCTGCTGGTCTGCCTGGCCCTGCTCGGCGTCTATC
TCTGCCTCGATCTGCGCGACGTCGCCTGGCACAACGCGCGCCGCAACGCGTCGAACCTGCTGGCGGTCATCGAGGAGGGC
GTCGGCCACAGCCTGCGGGTCTACGATCTCTCCCTGCAGAACTCCGCGCGCCTCGCGAGCCGCACCGACATCGGGGCCCT
GGAGCCGGAGATCCGGCGCTTGGCGCTGTTCGACACGGCGGTGGCGGGGTCCGGGCTCGGTCCGATCGCCGTCACGGACG
CGGCCGGCGATGTCCGTCTGACCAGTGATCCGTCCGTTCACGCCCGGCCCAACCTGCGCGCGCTGCCGGAATTCGAGTTC
CACCGGTCGAACCCCGATGGCGGCCTGATCCTGTCCGGCCCGACCGTGTCGCGGCTGACCGGGGAGCCGATCATCCGCAT
GACCCGCCGGATCCGGACGCCGGACGGTTCGTTCGCCGGGATCGTCTCGGGATCGATCAAGCTCGCGCATTTCCAGGCCT
TGTTCGAGCGTCTGCACTTCGACGACGGCATCGCCCTGAACGTCTTCCACCGGGACGGAACGCTCCTGATCCGGGCGCCG
GCCCTCCCGCAGGCGCTCGGCCTGAGCATCAGCGCGAGCACGGGCTACAAGATGTACCGGGCCACGCCGCGCGGCGAGTT
CCAGGGGCGCTCGTTCCTGGACGGCGTCGAGCGGGTCTACAGCTTCGCCGACCTCGGCGACCTGCCGCTGATCGTGACCG
TGGCGACGGATGTCGACAGCATCCGCGGCGTCTGGATCTACAAGGCCGCGATCGTCGGCGTCCTGATCCTGTGCCTCTGC
GGCCTGTCCTTCGGCCTGACGGTCCTGCTGCACCGGGAGGTGGGGCGCCATGTGGCCGCCGAGGCCTCCACCCGCGAGGC
GAACGCCGCGCTCGCCGTGCTCGCGCGGACCGACGGCCTGACCGGCCTGCCGAACCGGCGCAGCTACGACGAGCACTTCG
CCGTGGAGTGGAAGCGTGCCGTCCAGCTCCGGACACCCCTGGCGCTGATGATCGTCGATGCCGACCACTTCAAGCAGTTC
AACGACCGCTTCGGCCACCAGCGCGGCGACGAGGTGCTGAGGGCGGTGGCGGACTGCCTGCAGCGGACCCTCGATACCGC
CGGGCTCAGCTTCCGGATCGGCGGCGAGGAGTTCGTCGCCCTGCTGCCGGGCCTCGACGCGACGGCCGCCAGCGTCGCGG
CGGAGCGCATCCGCCGCGCGGTGGTGAACCTCCGCATCCCCCACGCCCCGGAGGTCGGGGGCAGCGCCACGGTGAGCATC
GGCGTCGCCAGCGCAGATCCCGGCGGCGGCGATCCGCCCGAGGGCCTGTTCCCGGCGGCGGACGCGGCCCTCTACGCGGC
CAAGAAGGCCGGCCGCAACCGCGTCCGGGCCGCCGCGCCGGCCGATCCCGTGACCCTGGCGCTGCGGGCCTGA

Upstream 100 bases:

>100_bases
GGGCCTCTATTTGTATAGGCAGCGATTTGGCGCTTCTTAATGCTGCTAATAACCGCTTTTTCAATCTTCGCCGACGTAAG
ATCGGGTCAACAGCAAGTCC

Downstream 100 bases:

>100_bases
GCCGGCCCGCGCTCAGAGCATCGGCAGCATCCGGGGGCGCGGTCCGCGCGGGAAATGCGCGTCGATCAGGGCGATCTCGG
CCGCGCCGAGGTGCAGGTCC

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MNRNDAAGGSPNESMLLRATATAIRAHLDDRASRLIAVGGTCLLVCLALLGVYLCLDLRDVAWHNARRNASNLLAVIEEG
VGHSLRVYDLSLQNSARLASRTDIGALEPEIRRLALFDTAVAGSGLGPIAVTDAAGDVRLTSDPSVHARPNLRALPEFEF
HRSNPDGGLILSGPTVSRLTGEPIIRMTRRIRTPDGSFAGIVSGSIKLAHFQALFERLHFDDGIALNVFHRDGTLLIRAP
ALPQALGLSISASTGYKMYRATPRGEFQGRSFLDGVERVYSFADLGDLPLIVTVATDVDSIRGVWIYKAAIVGVLILCLC
GLSFGLTVLLHREVGRHVAAEASTREANAALAVLARTDGLTGLPNRRSYDEHFAVEWKRAVQLRTPLALMIVDADHFKQF
NDRFGHQRGDEVLRAVADCLQRTLDTAGLSFRIGGEEFVALLPGLDATAASVAAERIRRAVVNLRIPHAPEVGGSATVSI
GVASADPGGGDPPEGLFPAADAALYAAKKAGRNRVRAAAPADPVTLALRA

Sequences:

>Translated_530_residues
MNRNDAAGGSPNESMLLRATATAIRAHLDDRASRLIAVGGTCLLVCLALLGVYLCLDLRDVAWHNARRNASNLLAVIEEG
VGHSLRVYDLSLQNSARLASRTDIGALEPEIRRLALFDTAVAGSGLGPIAVTDAAGDVRLTSDPSVHARPNLRALPEFEF
HRSNPDGGLILSGPTVSRLTGEPIIRMTRRIRTPDGSFAGIVSGSIKLAHFQALFERLHFDDGIALNVFHRDGTLLIRAP
ALPQALGLSISASTGYKMYRATPRGEFQGRSFLDGVERVYSFADLGDLPLIVTVATDVDSIRGVWIYKAAIVGVLILCLC
GLSFGLTVLLHREVGRHVAAEASTREANAALAVLARTDGLTGLPNRRSYDEHFAVEWKRAVQLRTPLALMIVDADHFKQF
NDRFGHQRGDEVLRAVADCLQRTLDTAGLSFRIGGEEFVALLPGLDATAASVAAERIRRAVVNLRIPHAPEVGGSATVSI
GVASADPGGGDPPEGLFPAADAALYAAKKAGRNRVRAAAPADPVTLALRA
>Mature_530_residues
MNRNDAAGGSPNESMLLRATATAIRAHLDDRASRLIAVGGTCLLVCLALLGVYLCLDLRDVAWHNARRNASNLLAVIEEG
VGHSLRVYDLSLQNSARLASRTDIGALEPEIRRLALFDTAVAGSGLGPIAVTDAAGDVRLTSDPSVHARPNLRALPEFEF
HRSNPDGGLILSGPTVSRLTGEPIIRMTRRIRTPDGSFAGIVSGSIKLAHFQALFERLHFDDGIALNVFHRDGTLLIRAP
ALPQALGLSISASTGYKMYRATPRGEFQGRSFLDGVERVYSFADLGDLPLIVTVATDVDSIRGVWIYKAAIVGVLILCLC
GLSFGLTVLLHREVGRHVAAEASTREANAALAVLARTDGLTGLPNRRSYDEHFAVEWKRAVQLRTPLALMIVDADHFKQF
NDRFGHQRGDEVLRAVADCLQRTLDTAGLSFRIGGEEFVALLPGLDATAASVAAERIRRAVVNLRIPHAPEVGGSATVSI
GVASADPGGGDPPEGLFPAADAALYAAKKAGRNRVRAAAPADPVTLALRA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=184, Percent_Identity=37.5, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787262, Length=222, Percent_Identity=31.5315315315315, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI87081881, Length=164, Percent_Identity=41.4634146341463, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082007, Length=174, Percent_Identity=39.0804597701149, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=37.9746835443038, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081977, Length=199, Percent_Identity=33.1658291457286, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=38.4146341463415, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787802, Length=131, Percent_Identity=38.1679389312977, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787541, Length=179, Percent_Identity=31.8435754189944, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788381, Length=181, Percent_Identity=32.0441988950276, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=31.9018404907975, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081974, Length=231, Percent_Identity=25.1082251082251, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 56499; Mature: 56499

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNDAAGGSPNESMLLRATATAIRAHLDDRASRLIAVGGTCLLVCLALLGVYLCLDLRD
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHH
VAWHNARRNASNLLAVIEEGVGHSLRVYDLSLQNSARLASRTDIGALEPEIRRLALFDTA
HHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHH
VAGSGLGPIAVTDAAGDVRLTSDPSVHARPNLRALPEFEFHRSNPDGGLILSGPTVSRLT
HCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCEECCCCCCCEEECCCCHHHCC
GEPIIRMTRRIRTPDGSFAGIVSGSIKLAHFQALFERLHFDDGIALNVFHRDGTLLIRAP
CCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECC
ALPQALGLSISASTGYKMYRATPRGEFQGRSFLDGVERVYSFADLGDLPLIVTVATDVDS
CCCHHHCCEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
IRGVWIYKAAIVGVLILCLCGLSFGLTVLLHREVGRHVAAEASTREANAALAVLARTDGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
TGLPNRRSYDEHFAVEWKRAVQLRTPLALMIVDADHFKQFNDRFGHQRGDEVLRAVADCL
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHH
QRTLDTAGLSFRIGGEEFVALLPGLDATAASVAAERIRRAVVNLRIPHAPEVGGSATVSI
HHHHHHCCCEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEE
GVASADPGGGDPPEGLFPAADAALYAAKKAGRNRVRAAAPADPVTLALRA
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEC
>Mature Secondary Structure
MNRNDAAGGSPNESMLLRATATAIRAHLDDRASRLIAVGGTCLLVCLALLGVYLCLDLRD
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHH
VAWHNARRNASNLLAVIEEGVGHSLRVYDLSLQNSARLASRTDIGALEPEIRRLALFDTA
HHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHH
VAGSGLGPIAVTDAAGDVRLTSDPSVHARPNLRALPEFEFHRSNPDGGLILSGPTVSRLT
HCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCEECCCCCCCEEECCCCHHHCC
GEPIIRMTRRIRTPDGSFAGIVSGSIKLAHFQALFERLHFDDGIALNVFHRDGTLLIRAP
CCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECC
ALPQALGLSISASTGYKMYRATPRGEFQGRSFLDGVERVYSFADLGDLPLIVTVATDVDS
CCCHHHCCEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
IRGVWIYKAAIVGVLILCLCGLSFGLTVLLHREVGRHVAAEASTREANAALAVLARTDGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
TGLPNRRSYDEHFAVEWKRAVQLRTPLALMIVDADHFKQFNDRFGHQRGDEVLRAVADCL
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHH
QRTLDTAGLSFRIGGEEFVALLPGLDATAASVAAERIRRAVVNLRIPHAPEVGGSATVSI
HHHHHHCCCEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEE
GVASADPGGGDPPEGLFPAADAALYAAKKAGRNRVRAAAPADPVTLALRA
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]