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The map label for this gene is cya2 [H]

Identifier: 170749577

GI number: 170749577

Start: 3349818

End: 3350891

Strand: Reverse

Name: cya2 [H]

Synonym: Mrad2831_3172

Alternate gene names: 170749577

Gene position: 3350891-3349818 (Counterclockwise)

Preceding gene: 170749579

Following gene: 170749576

Centisome position: 55.13

GC content: 72.72

Gene sequence:

>1074_bases
ATGCTGCCGGCCCACCGGATATTCTGGGGTCTGATCCTGCTGGCGGCGGCCGGCGCGGGGTTGCTCTACAACATCATCTT
CGCGGCCGGAGCCTCGCCGCTCGCCGGATTTACCTACGGCCTCTGCATGGGCGCCACGGTGCTGGCCTTCGACCGCGGGC
TGATCCTGGCCGGGCTGCAGGCGCGGATCCGCCGGCTGCCGGCCTGGCTCTACGTGCTGGCCGCGGAACTCGCCTACGTG
CTGATGATCATGGCGGGCAACGCGCTGGGCGGCCTGGTCGTCTGGGCGTTCGCCCTGACACCGGACGACCTCACGACCGC
GACCCGCATGACGGCGCGGGTCCTGGCCTACGCCCTGGCGGTGTCGGGCCTGCTGGTCTTCGTCATCCGGATGCGCGACC
TGATCGGCGGCGAGGTGTTCGTGAACTTCATGATCGGCCGCTACCACAAGCCGGTGGCGGAGGAGCGGGTCTTCCTGTTC
CTCGACGTCGTCGGCTCCACGGCCTTCGCGGAGACTCACGGCGACCTCCGCGCGCAGGAATATCTCAGCGCGGTGTTCGC
GACGCTCGCCGAGCCGGTGCGGCGCAACGGCGGCTCGGTGGACGACTACGTCGGCGATCTCGCCATGGTGACGTGGCCGA
TGGCCCGCGGCCTGAAGGACGCGCGCTGCGTGACCTGCGTGTTCGAGGTGCTCGATCGGATCGAGGCGGACGCCGCGGCC
TGGCAAGCCCGGTTCGGCACGGTGCCGCGGCTGCGGGCGGCCCTGCACGGCGGCTCGGTGGTCACGGCCGAAGTCGGGGT
CGACCGCCACAAGATCGCGTATTTCGGCGACGCCGTGAACGTGACGTCGCGGATCGAGGCCCTGTGCCGCCCCCTCGGCG
TCGGCATCCTGATCTCGCAGGATCTCCTCAACCGCCTGCCGCGCCTGCCGGCCGGGGTGCGGGCGCGGTCCCTCGGCGCC
CACGCGCTCCGCGGCCGCGGTGCGCCGCTGTCCGTCGCGACGCTGGAGCGCGGGCCCGCCGAGACCGCGCCGGTGGCGGA
CCTGTCGCCCCGGCGCGCCGCGGTCGCCCGCTGA

Upstream 100 bases:

>100_bases
TTGCCGAGCCTGCGCTGCCCCGCGCAGCGCCGCCGCGCAGGGCCACGCGACACCCGGACCCGCGCACGGTCCGTCGGCTG
GCCCTGCTGGAGATGCGTCG

Downstream 100 bases:

>100_bases
TGTCCGGGTCGAGCACCGCGCGGGCGAACGCCCTGATCGCCGTGAAGATGGCGCTGCGCTTCGGGCTGCCGCTGATCGGA
CTCGTCGTCTTCGGCCGCGC

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2 [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLPAHRIFWGLILLAAAGAGLLYNIIFAAGASPLAGFTYGLCMGATVLAFDRGLILAGLQARIRRLPAWLYVLAAELAYV
LMIMAGNALGGLVVWAFALTPDDLTTATRMTARVLAYALAVSGLLVFVIRMRDLIGGEVFVNFMIGRYHKPVAEERVFLF
LDVVGSTAFAETHGDLRAQEYLSAVFATLAEPVRRNGGSVDDYVGDLAMVTWPMARGLKDARCVTCVFEVLDRIEADAAA
WQARFGTVPRLRAALHGGSVVTAEVGVDRHKIAYFGDAVNVTSRIEALCRPLGVGILISQDLLNRLPRLPAGVRARSLGA
HALRGRGAPLSVATLERGPAETAPVADLSPRRAAVAR

Sequences:

>Translated_357_residues
MLPAHRIFWGLILLAAAGAGLLYNIIFAAGASPLAGFTYGLCMGATVLAFDRGLILAGLQARIRRLPAWLYVLAAELAYV
LMIMAGNALGGLVVWAFALTPDDLTTATRMTARVLAYALAVSGLLVFVIRMRDLIGGEVFVNFMIGRYHKPVAEERVFLF
LDVVGSTAFAETHGDLRAQEYLSAVFATLAEPVRRNGGSVDDYVGDLAMVTWPMARGLKDARCVTCVFEVLDRIEADAAA
WQARFGTVPRLRAALHGGSVVTAEVGVDRHKIAYFGDAVNVTSRIEALCRPLGVGILISQDLLNRLPRLPAGVRARSLGA
HALRGRGAPLSVATLERGPAETAPVADLSPRRAAVAR
>Mature_357_residues
MLPAHRIFWGLILLAAAGAGLLYNIIFAAGASPLAGFTYGLCMGATVLAFDRGLILAGLQARIRRLPAWLYVLAAELAYV
LMIMAGNALGGLVVWAFALTPDDLTTATRMTARVLAYALAVSGLLVFVIRMRDLIGGEVFVNFMIGRYHKPVAEERVFLF
LDVVGSTAFAETHGDLRAQEYLSAVFATLAEPVRRNGGSVDDYVGDLAMVTWPMARGLKDARCVTCVFEVLDRIEADAAA
WQARFGTVPRLRAALHGGSVVTAEVGVDRHKIAYFGDAVNVTSRIEALCRPLGVGILISQDLLNRLPRLPAGVRARSLGA
HALRGRGAPLSVATLERGPAETAPVADLSPRRAAVAR

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 38163; Mature: 38163

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPAHRIFWGLILLAAAGAGLLYNIIFAAGASPLAGFTYGLCMGATVLAFDRGLILAGLQ
CCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
ARIRRLPAWLYVLAAELAYVLMIMAGNALGGLVVWAFALTPDDLTTATRMTARVLAYALA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VSGLLVFVIRMRDLIGGEVFVNFMIGRYHKPVAEERVFLFLDVVGSTAFAETHGDLRAQE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHEEEEEHHCCHHHHHCCCCHHHHH
YLSAVFATLAEPVRRNGGSVDDYVGDLAMVTWPMARGLKDARCVTCVFEVLDRIEADAAA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WQARFGTVPRLRAALHGGSVVTAEVGVDRHKIAYFGDAVNVTSRIEALCRPLGVGILISQ
HHHHHCCCHHHHHHHCCCCEEEEECCCCCHHEEEECCHHHHHHHHHHHHHHHCCHHEEHH
DLLNRLPRLPAGVRARSLGAHALRGRGAPLSVATLERGPAETAPVADLSPRRAAVAR
HHHHHCCCCCCCCHHHHCCHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MLPAHRIFWGLILLAAAGAGLLYNIIFAAGASPLAGFTYGLCMGATVLAFDRGLILAGLQ
CCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
ARIRRLPAWLYVLAAELAYVLMIMAGNALGGLVVWAFALTPDDLTTATRMTARVLAYALA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VSGLLVFVIRMRDLIGGEVFVNFMIGRYHKPVAEERVFLFLDVVGSTAFAETHGDLRAQE
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHEEEEEHHCCHHHHHCCCCHHHHH
YLSAVFATLAEPVRRNGGSVDDYVGDLAMVTWPMARGLKDARCVTCVFEVLDRIEADAAA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
WQARFGTVPRLRAALHGGSVVTAEVGVDRHKIAYFGDAVNVTSRIEALCRPLGVGILISQ
HHHHHCCCHHHHHHHCCCCEEEEECCCCCHHEEEECCHHHHHHHHHHHHHHHCCHHEEHH
DLLNRLPRLPAGVRARSLGAHALRGRGAPLSVATLERGPAETAPVADLSPRRAAVAR
HHHHHCCCCCCCCHHHHCCHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7750735; 11481430 [H]