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The map label for this gene is cobK [H]

Identifier: 170749525

GI number: 170749525

Start: 3300177

End: 3300974

Strand: Reverse

Name: cobK [H]

Synonym: Mrad2831_3120

Alternate gene names: 170749525

Gene position: 3300974-3300177 (Counterclockwise)

Preceding gene: 170749530

Following gene: 170749515

Centisome position: 54.31

GC content: 76.57

Gene sequence:

>798_bases
ATGAAAACGCCGCCCTCCACCGCCGGCACGCTGCGGGTCCTGATCCTCGGCGGGACCGGCGAGGCGAGCGCCCTGGTCCG
GTCGCTCGCCGGCCGGGCGGATCGCGCCGTGACGCTCTCGCTGGCAGGCCGGACCGCGGCGCCGAAGCCCGAGCCGGTGC
CGACCCGGATCGGCGGGTTCGGCGGCGCCGAGGGTCTCGCCCGCTACCTGCGGACCGAGGCGATCAGCCGCCTGATCGAC
GCGACCCACCCGTTCGCCGCGCAGATGTCGATCAACGCCGCGCGCGCGGCGGCCCTGACGGGGGTGCCGCTCCTCGCGAT
CCGCCGGCCCGCCTGGAGCCGCGAGCGCGGCGACGACTGGATCGAGGTCGACGGGATGGCGGAGGCGATCGCCGCCCTCG
GCGCGGAACCCCGGCGCGTGTTCCTGACGATCGGTCGGCAGGAGGCCGGGGCCTTCGCGGCGGCGCCCCAGCACAGCTAT
CTGGCCCGGACGGTCGAGCCGCTGGCCGGGATCCTGCCGGTGCCGCATCTCACCGCCCTGGAGGCGCGCGGGCCCTTCGA
CGCCGCGTCCGAGGCGGCCCTGATGCGGGCGAACCGGATCGAGATCGTGGTCAGCAAGAACGCCGGCGGCGCGGCGACCT
ACGGCAAGATCGCGGCGGCGCGCAGCCTCGGCCTCCCGGTCGTGATGGTGCGCCGGCCGGCCAAGCCCGACGTGCCCCGC
GTCGCGGACGAAGCGGGCGCGCGCCGCTGGCTGGACGCAAGCGATCACGCCGGTCCCTCGACCTTGCGGGCGGTGTAG

Upstream 100 bases:

>100_bases
GGCGGACGGCGTCAGCCCGGCCCGCCCGTCCTCGCCGATCCCGACGATCGACAGCCACGGGACGCTCGACAGGCGATCAG
CGCTCATGGACAAGACGCCC

Downstream 100 bases:

>100_bases
ACGAACGGCGCCCGGCCGGCGCGCGGGATCAGCCGCGTCGTCGAGGCGCCCAGGATCACCATCGTGGCCATGTCGGCCGC
CACCGCGGGCGCCTCCGCGA

Product: precorrin-6A reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKTPPSTAGTLRVLILGGTGEASALVRSLAGRADRAVTLSLAGRTAAPKPEPVPTRIGGFGGAEGLARYLRTEAISRLID
ATHPFAAQMSINAARAAALTGVPLLAIRRPAWSRERGDDWIEVDGMAEAIAALGAEPRRVFLTIGRQEAGAFAAAPQHSY
LARTVEPLAGILPVPHLTALEARGPFDAASEAALMRANRIEIVVSKNAGGAATYGKIAAARSLGLPVVMVRRPAKPDVPR
VADEAGARRWLDASDHAGPSTLRAV

Sequences:

>Translated_265_residues
MKTPPSTAGTLRVLILGGTGEASALVRSLAGRADRAVTLSLAGRTAAPKPEPVPTRIGGFGGAEGLARYLRTEAISRLID
ATHPFAAQMSINAARAAALTGVPLLAIRRPAWSRERGDDWIEVDGMAEAIAALGAEPRRVFLTIGRQEAGAFAAAPQHSY
LARTVEPLAGILPVPHLTALEARGPFDAASEAALMRANRIEIVVSKNAGGAATYGKIAAARSLGLPVVMVRRPAKPDVPR
VADEAGARRWLDASDHAGPSTLRAV
>Mature_265_residues
MKTPPSTAGTLRVLILGGTGEASALVRSLAGRADRAVTLSLAGRTAAPKPEPVPTRIGGFGGAEGLARYLRTEAISRLID
ATHPFAAQMSINAARAAALTGVPLLAIRRPAWSRERGDDWIEVDGMAEAIAALGAEPRRVFLTIGRQEAGAFAAAPQHSY
LARTVEPLAGILPVPHLTALEARGPFDAASEAALMRANRIEIVVSKNAGGAATYGKIAAARSLGLPVVMVRRPAKPDVPR
VADEAGARRWLDASDHAGPSTLRAV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 27547; Mature: 27547

Theoretical pI: Translated: 11.25; Mature: 11.25

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPPSTAGTLRVLILGGTGEASALVRSLAGRADRAVTLSLAGRTAAPKPEPVPTRIGGF
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
GGAEGLARYLRTEAISRLIDATHPFAAQMSINAARAAALTGVPLLAIRRPAWSRERGDDW
CCHHHHHHHHHHHHHHHHHHCCCCCHHHEECHHHHHHHHCCCCEEEEECCCCCCCCCCCE
IEVDGMAEAIAALGAEPRRVFLTIGRQEAGAFAAAPQHSYLARTVEPLAGILPVPHLTAL
EEECHHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCEEE
EARGPFDAASEAALMRANRIEIVVSKNAGGAATYGKIAAARSLGLPVVMVRRPAKPDVPR
CCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCH
VADEAGARRWLDASDHAGPSTLRAV
HHHHHHHHHCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MKTPPSTAGTLRVLILGGTGEASALVRSLAGRADRAVTLSLAGRTAAPKPEPVPTRIGGF
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
GGAEGLARYLRTEAISRLIDATHPFAAQMSINAARAAALTGVPLLAIRRPAWSRERGDDW
CCHHHHHHHHHHHHHHHHHHCCCCCHHHEECHHHHHHHHCCCCEEEEECCCCCCCCCCCE
IEVDGMAEAIAALGAEPRRVFLTIGRQEAGAFAAAPQHSYLARTVEPLAGILPVPHLTAL
EEECHHHHHHHHHCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCEEE
EARGPFDAASEAALMRANRIEIVVSKNAGGAATYGKIAAARSLGLPVVMVRRPAKPDVPR
CCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCH
VADEAGARRWLDASDHAGPSTLRAV
HHHHHHHHHCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]