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The map label for this gene is yogA [H]

Identifier: 170749472

GI number: 170749472

Start: 3240061

End: 3241083

Strand: Reverse

Name: yogA [H]

Synonym: Mrad2831_3067

Alternate gene names: 170749472

Gene position: 3241083-3240061 (Counterclockwise)

Preceding gene: 170749473

Following gene: 170749471

Centisome position: 53.33

GC content: 70.09

Gene sequence:

>1023_bases
ATGCGAGCCCTCCAGCTTTTCGGCGACCGCGACCTGCGCCTCACCGAGATCGAGCCGCCGCCCGCGCCCGGGGCCGACGA
GGTCCGGATCCGCATCCGCGCGGTCGGCCTCAACTTCATCGACGTCTGGGGCTTCCGCGGCATGGCCTTCGCCAAGCGGA
AGATGCCGCTGATCGTCGGCGCGGAGGCGGCCGGGACCGTCGAGTCGGTCGGGGCGGGCGTCACCGGCCTCGTCGCGGGC
GACCGGGTCGTGCCCTACGGCGCCATGACCTGCGGCCGGTGCAAGGCCTGCCGCGAGGGGCGCGACAACCTCTGCGAGGA
CGTGTCCGGCGTGATGGGCTTCCATCTCGACGGCTTCGCCCGGGAGCTCGTGACCATGCCGGCCCGCCTCGTCGTGAAGG
TGCCGGACGGCGTCAGCGACACCGACGCCGCCTGCGCGGGCATCGCCTTCGGCACGGTCCAGCACATGCTGTTCGACAAC
GCCCGCCTGGAGCCCGGCGAGAGCGTCCTGGTCCATGCCGGCGGCTCGGGAATCGGCACCGCGGCGATCCGCATGGCCAA
GGCGATCGGCTGCACGGTCTACACGACGGTCGGCGACGACGAGAAGGGCCGTAAGGCGGCAGAACTCGGCGCCGACCACG
TCATCAACTACCGCACCGAGCGGTTCGAGGGCGAGGTCCGCCGGCTGACGAAGCGCAAGGGCGTCGACGTGGTGTTCGAG
CACGTCGGCGCCGACACCTGGAACGGCTCCCTGCTCTGCCTGAAGCGCGGCGGTCGCCTCGTGACCTGCGGATCGACCTC
GGGCGTCTCGGCGACGATGAACCTGATGCAGCTGTTCCAGCAGCAGTACCGCATCACCGGCTCGTTCGGCTGCTCGCTCG
CGAATATCGGTCAGGCCCTCGCCAAGATGGACGCGGGTATTCGACCGGTTGTCGATACCGTGTACCCGCTGGCGGACTTC
GCGCAGGGTCTGGAGCGACTCGAATCGCGCCGGGTCTTCGGCAAGATCCTCGTCAGCCTGTAG

Upstream 100 bases:

>100_bases
ACGACACGCCGAGCCGCACCACGTGGTGCCGGGTGAAGGCCGGACGCGCCCTGGGGTGGGCGCGGCGCCGCTACCTGGCG
CCGGAGTGACGAGAGACACG

Downstream 100 bases:

>100_bases
CGCCGGCCACGGCACACCGGCACGGCGCGACACCGGACCGTAGGCGGCGATCCGCATTTCGCGCCGCGACAGACTTGGCG
TAAACGTCGCCGTACGGGTC

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRALQLFGDRDLRLTEIEPPPAPGADEVRIRIRAVGLNFIDVWGFRGMAFAKRKMPLIVGAEAAGTVESVGAGVTGLVAG
DRVVPYGAMTCGRCKACREGRDNLCEDVSGVMGFHLDGFARELVTMPARLVVKVPDGVSDTDAACAGIAFGTVQHMLFDN
ARLEPGESVLVHAGGSGIGTAAIRMAKAIGCTVYTTVGDDEKGRKAAELGADHVINYRTERFEGEVRRLTKRKGVDVVFE
HVGADTWNGSLLCLKRGGRLVTCGSTSGVSATMNLMQLFQQQYRITGSFGCSLANIGQALAKMDAGIRPVVDTVYPLADF
AQGLERLESRRVFGKILVSL

Sequences:

>Translated_340_residues
MRALQLFGDRDLRLTEIEPPPAPGADEVRIRIRAVGLNFIDVWGFRGMAFAKRKMPLIVGAEAAGTVESVGAGVTGLVAG
DRVVPYGAMTCGRCKACREGRDNLCEDVSGVMGFHLDGFARELVTMPARLVVKVPDGVSDTDAACAGIAFGTVQHMLFDN
ARLEPGESVLVHAGGSGIGTAAIRMAKAIGCTVYTTVGDDEKGRKAAELGADHVINYRTERFEGEVRRLTKRKGVDVVFE
HVGADTWNGSLLCLKRGGRLVTCGSTSGVSATMNLMQLFQQQYRITGSFGCSLANIGQALAKMDAGIRPVVDTVYPLADF
AQGLERLESRRVFGKILVSL
>Mature_340_residues
MRALQLFGDRDLRLTEIEPPPAPGADEVRIRIRAVGLNFIDVWGFRGMAFAKRKMPLIVGAEAAGTVESVGAGVTGLVAG
DRVVPYGAMTCGRCKACREGRDNLCEDVSGVMGFHLDGFARELVTMPARLVVKVPDGVSDTDAACAGIAFGTVQHMLFDN
ARLEPGESVLVHAGGSGIGTAAIRMAKAIGCTVYTTVGDDEKGRKAAELGADHVINYRTERFEGEVRRLTKRKGVDVVFE
HVGADTWNGSLLCLKRGGRLVTCGSTSGVSATMNLMQLFQQQYRITGSFGCSLANIGQALAKMDAGIRPVVDTVYPLADF
AQGLERLESRRVFGKILVSL

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=339, Percent_Identity=28.023598820059, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI194239674, Length=337, Percent_Identity=25.8160237388724, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI13236495, Length=337, Percent_Identity=25.8160237388724, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI22538446, Length=348, Percent_Identity=26.7241379310345, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI22538444, Length=348, Percent_Identity=26.7241379310345, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI24308257, Length=352, Percent_Identity=27.5568181818182, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4501929, Length=361, Percent_Identity=29.9168975069252, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI34577061, Length=268, Percent_Identity=32.089552238806, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI71565154, Length=258, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI71565152, Length=319, Percent_Identity=30.4075235109718, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4501933, Length=267, Percent_Identity=32.2097378277154, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI156627571, Length=334, Percent_Identity=29.0419161676647, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI41872631, Length=252, Percent_Identity=29.7619047619048, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI194239676, Length=331, Percent_Identity=24.4712990936556, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI71743840, Length=256, Percent_Identity=29.296875, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI262073058, Length=256, Percent_Identity=29.296875, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI197927207, Length=178, Percent_Identity=28.0898876404494, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI28557745, Length=258, Percent_Identity=29.4573643410853, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4501939, Length=305, Percent_Identity=27.2131147540984, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI156523966, Length=305, Percent_Identity=27.2131147540984, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1790485, Length=342, Percent_Identity=31.5789473684211, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790045, Length=349, Percent_Identity=28.080229226361, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788073, Length=335, Percent_Identity=29.5522388059701, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787863, Length=219, Percent_Identity=31.5068493150685, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081918, Length=289, Percent_Identity=27.681660899654, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI226510992, Length=316, Percent_Identity=27.8481012658228, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082125, Length=311, Percent_Identity=28.2958199356913, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788075, Length=262, Percent_Identity=26.7175572519084, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=266, Percent_Identity=30.8270676691729, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562878, Length=225, Percent_Identity=32.8888888888889, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562584, Length=324, Percent_Identity=24.3827160493827, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=231, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565904, Length=300, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25146526, Length=260, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562582, Length=329, Percent_Identity=23.7082066869301, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997431, Length=262, Percent_Identity=28.6259541984733, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=356, Percent_Identity=26.685393258427, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=325, Percent_Identity=22.7692307692308, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=325, Percent_Identity=24.3076923076923, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=323, Percent_Identity=25.3869969040248, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=339, Percent_Identity=24.188790560472, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=339, Percent_Identity=25.9587020648968, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319955, Length=339, Percent_Identity=25.6637168141593, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330659, Length=140, Percent_Identity=33.5714285714286, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19920632, Length=140, Percent_Identity=33.5714285714286, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24581345, Length=225, Percent_Identity=25.7777777777778, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17737895, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17737897, Length=251, Percent_Identity=30.2788844621514, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17137530, Length=231, Percent_Identity=29.4372294372294, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550770, Length=332, Percent_Identity=27.710843373494, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221457811, Length=332, Percent_Identity=27.710843373494, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45551930, Length=332, Percent_Identity=27.710843373494, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36310; Mature: 36310

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALQLFGDRDLRLTEIEPPPAPGADEVRIRIRAVGLNFIDVWGFRGMAFAKRKMPLIVG
CCCEECCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCEEECCCCCCHHHHHHCCCEEEE
AEAAGTVESVGAGVTGLVAGDRVVPYGAMTCGRCKACREGRDNLCEDVSGVMGFHLDGFA
CCCCCCHHHHCCCEEEEEECCEECCCCCCCHHHHHHHHHCHHHHHHHHHHHHCCCHHHHH
RELVTMPARLVVKVPDGVSDTDAACAGIAFGTVQHMLFDNARLEPGESVLVHAGGSGIGT
HHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
AAIRMAKAIGCTVYTTVGDDEKGRKAAELGADHVINYRTERFEGEVRRLTKRKGVDVVFE
HHHHHHHHHCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
HVGADTWNGSLLCLKRGGRLVTCGSTSGVSATMNLMQLFQQQYRITGSFGCSLANIGQAL
HCCCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH
AKMDAGIRPVVDTVYPLADFAQGLERLESRRVFGKILVSL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRALQLFGDRDLRLTEIEPPPAPGADEVRIRIRAVGLNFIDVWGFRGMAFAKRKMPLIVG
CCCEECCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCEEECCCCCCHHHHHHCCCEEEE
AEAAGTVESVGAGVTGLVAGDRVVPYGAMTCGRCKACREGRDNLCEDVSGVMGFHLDGFA
CCCCCCHHHHCCCEEEEEECCEECCCCCCCHHHHHHHHHCHHHHHHHHHHHHCCCHHHHH
RELVTMPARLVVKVPDGVSDTDAACAGIAFGTVQHMLFDNARLEPGESVLVHAGGSGIGT
HHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
AAIRMAKAIGCTVYTTVGDDEKGRKAAELGADHVINYRTERFEGEVRRLTKRKGVDVVFE
HHHHHHHHHCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
HVGADTWNGSLLCLKRGGRLVTCGSTSGVSATMNLMQLFQQQYRITGSFGCSLANIGQAL
HCCCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH
AKMDAGIRPVVDTVYPLADFAQGLERLESRRVFGKILVSL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]